RPS-BLAST 2.2.4 [Aug-26-2002]

Query= gi|1786183|gb|AAC73113.1| (AE000111) aspartokinase I,
homoserine dehydrogenase I [Escherichia coli]
         (820 letters)



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gnl|CDD|3919 smart00483, POLXc, DNA polymerase X family; include...    28   0.064
gnl|CDD|7379 smart00533, MUTSd, DNA-binding domain of DNA mismat...    26   0.47 
gnl|CDD|178 smart00202, SR, Scavenger receptor Cys-rich; The sea...    22   4.5  
gnl|CDD|8977 smart00359, PUA, Putative RNA-binding Domain in Pse...    22   7.0  
gnl|CDD|7370 smart00486, POLBc, DNA polymerase type-B family; DN...    22   7.6  
gnl|CDD|28 smart00035, CLa, CLUSTERIN alpha chain;                     21   7.6  
gnl|CDD|8994 smart00450, RHOD, Rhodanese Homology Domain; An alp...    22   8.0  

>gnl|CDD|3919 smart00483, POLXc, DNA polymerase X family; includes vertebrate
           polymerase beta and terminal
           deoxynucleotidyltransferases
          Length = 335

 Score = 28.3 bits (63), Expect = 0.064
 Identities = 11/57 (19%), Positives = 21/57 (36%), Gaps = 3/57 (5%)

Query: 599 SRRKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSE 655
           ++RK  Y         V+++L   +N+  +L    GI       I   ++ G     
Sbjct: 23  NKRKCSY---FRKAASVLKSLPFPINSMKDLKGLPGIGDKIKKKIEEIIETGKLSKA 76


>gnl|CDD|7379 smart00533, MUTSd, DNA-binding domain of DNA mismatch repair MUTS
           family;
          Length = 310

 Score = 25.7 bits (56), Expect = 0.47
 Identities = 19/107 (17%), Positives = 36/107 (32%), Gaps = 21/107 (19%)

Query: 9   TSVANAERFLR------VADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDALP 62
                 +R LR      + D+ E N R                 L+   E     +  L 
Sbjct: 13  CKTPMGKRLLRRWLLQPLTDLKEINERL-----------DAVEELLENPELRQDLRGLLK 61

Query: 63  NISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGIS 109
            I D ER+ + +    A+ +    L +L   ++    +I+ +L  + 
Sbjct: 62  RIPDLERLLSRIKLSRASPR---DLLRLYDSLEG-LKEIRKLLESLE 104


>gnl|CDD|178 smart00202, SR, Scavenger receptor Cys-rich; The sea urchin egg
           peptide speract contains 4 repeats of SR domains that
           contain 6 conserved cysteines. May bind bacterial
           antigens in the protein MARCO
          Length = 101

 Score = 22.2 bits (47), Expect = 4.5
 Identities = 13/53 (24%), Positives = 20/53 (37%), Gaps = 2/53 (3%)

Query: 648 DEGMSFSEATTLAREMGYTEP--DPRDDLSGMDVARKLLILARETGRELELAD 698
           D+G    +A  + R++G+            G       L   R TG E  L+D
Sbjct: 27  DDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCTGTEASLSD 79


>gnl|CDD|8977 smart00359, PUA, Putative RNA-binding Domain in PseudoUridine
           synthase and Archaeosine transglycosylase;
          Length = 78

 Score = 21.8 bits (46), Expect = 7.0
 Identities = 10/40 (25%), Positives = 17/40 (42%), Gaps = 5/40 (12%)

Query: 135 AGVLEARGH-----NVTVIDPVEKLLAVGHYLESTVDIAE 169
            GV+   G       V ++D   + L +G    S+ +IA 
Sbjct: 22  PGVVRVDGDIKEGDVVVIVDEKGEPLGIGLANMSSEEIAR 61


>gnl|CDD|7370 smart00486, POLBc, DNA polymerase type-B family; DNA polymerase
           alpha, delta, epsilon and zeta chain (eukaryota), DNA
           polymerases in archaea, DNA polymerase II in e. coli,
           mitochondrial DNA polymerases and and virus DNA
           polymerases
          Length = 475

 Score = 21.7 bits (45), Expect = 7.6
 Identities = 8/33 (24%), Positives = 14/33 (42%), Gaps = 3/33 (9%)

Query: 247 KSMSYQEAMELSYFGAKVLHPRTI---TPIAQF 276
           K +  +   ++ Y G KVL P+      P+   
Sbjct: 275 KGLEPELKKKVKYEGGKVLEPKKGFYENPVLVL 307


>gnl|CDD|28 smart00035, CLa, CLUSTERIN alpha chain;
          Length = 215

 Score = 21.5 bits (45), Expect = 7.6
 Identities = 7/13 (53%), Positives = 9/13 (68%)

Query: 479 ALLEQLKRQQSWL 491
           +LLEQL  Q  W+
Sbjct: 129 SLLEQLNEQFGWV 141


>gnl|CDD|8994 smart00450, RHOD, Rhodanese Homology Domain; An alpha beta fold
           found duplicated in the Rhodanese protein. The the
           Cysteine containing enzymatically active version of the
           domain is also found in the CDC25 class of protein
           phosphatases and a variety of proteins such as sulfide
           dehydrogenases and stress proteins such as Senesence
           specific protein 1 in plants, PspE and GlpE in bacteria
           and cyanide and arsenate resistance proteins. Inactive
           versions with a loss of the cysteine are also seen in
           Dual specificity phosphatases, ubiquitin hydrolases from
           yeast and in sulfuryltransferases. These are likely to
           play a role in protein interactions
          Length = 109

 Score = 21.7 bits (45), Expect = 8.0
 Identities = 14/56 (25%), Positives = 17/56 (30%)

Query: 520 NWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVV 575
              E L +  E  +L   +          PVIV C S    A         GF  V
Sbjct: 38  PLSELLDRRGETDSLFEELLGSLGLDKDKPVIVYCRSGNRSAKAAWLLRELGFKNV 93


Lambda     K      H
   0.319    0.136    0.384 

Gapped
Lambda     K      H
   0.267   0.0574    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 1100, Extension: 100
Number of Hits to DB: 194,372
Number of Sequences: 0
Number of extensions: 14001
Number of successful extensions: 17
Number of sequences better than 10.0: 1
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17
length of query: 438
length of database: 75,508
effective HSP length: 68
effective length of query: 438
effective length of database: 31,988
effective search space: 14010744
effective search space used: 24054976
T: 11
A: 40
X1: 1600 (737.2 bits)
X2: 3800 (1463.8 bits)
X3: 6400 (2465.3 bits)
S1: 4100 (1892.0 bits)
S2: 43 (20.7 bits)
