!autogenerated-by:     Pathbase version 2.0
!saved-by:             	mgruenb
!date:                 	Mon Oct 20 20:15:35 BST 2003
!version: $Revision: 1.1 $
!The Pathbase mouse pathology ontology provides a description of mutant and transgenic mouse pathology phenotypes and incorporates 425 known mouse pathologies hierarchically organised as "instances of" pathological processes.
!Questions, comments and suggestions for amendment should be sent to the Co-ordinator, Dr. Paul Schofield, Dept. of Anatomy, University of Cambridge (PS@mole.bio.cam.ac.uk).
!The ontology was developed by the Pathbase consortium (http://www.pathbase.net) funded under the European Commission's Fifth Framework programme, Contract number QLRI-CT-1999-00320.
$pathology_ontology ; MPATH:0
 %cell and tissue damage ; MPATH:1
  %cell death ; MPATH:2
   %apoptosis ; MPATH:3 ; synonym:programmed cell death
   %necrosis ; MPATH:4
    %bridging necrosis ; MPATH:5
    %caseous necrosis ; MPATH:6
    %coagulation necrosis ; MPATH:7
    %fat necrosis ; MPATH:8
    %fibrinoid necrosis ; MPATH:9
    %gangrene ; MPATH:10 ; synonym:mortification
    %hemorrhagic necrosis ; MPATH:11
    %liquefactive necrosis ; MPATH:12
    %piecemeal necrosis ; MPATH:13
  %degenerative change ; MPATH:14
   %general degenerative change ; MPATH:15
    %myxoid/myxomatous degeneration ; MPATH:16 ; synonym:mucoid degeneration ; synonym:myxomatosis
   %subcellular defect ; MPATH:17
    %cytoskeletal defect ; MPATH:18
    %endoplasmic reticulum defect ; MPATH:19
    %golgi defect ; MPATH:20
    %lysosomal defect ; MPATH:21
    %mitochondrial defect ; MPATH:22
    %peroxysomal defect ; MPATH:23
    %plasma membrane defect ; MPATH:24
    %nuclear defect ; MPATH:460
   %tissue specific degenerative process ; MPATH:25
    %alopecia ; MPATH:26
    %arthrosis ; MPATH:27 ; synonym:osteoarthritis ; synonym:degenerative joint disease ; synonym:osteoarthrosis
    %atherosclerosis ; MPATH:28 ; synonym:nodular sclerosis
    %cataract ; MPATH:29
     %cataract- capsular-epithelial ; MPATH:461
     %cataract- nuclear and cortical ; MPATH:462
     %cataract- cortical liquefactive ; MPATH:463
     %cataract- lens extrusion ; MPATH:464
    %cystic medial necrosis ; MPATH:30 ; synonym:erdheim disease ; synonym:mucoid medial degeneration ; synonym:media necrosis aortae idiopathica cystica ; synonym:media necrosis of the aorta
    %emphysema ; MPATH:31
    %glaucoma ; MPATH:32
     %glaucoma developmental ; MPATH:465
     %glaucoma- open angle ; MPATH:466
     %glaucoma- angle closure ; MPATH:467
   %dystrophy ; MPATH:554
  %intracellular and extracellular accumulation ; MPATH:33
   %amyloid deposition ; MPATH:34
   %bile deposition ; MPATH:35
   %ceroid deposition ; MPATH:37
   %glycogen deposition ; MPATH:39
   %hyalinosis ; MPATH:40 ; synonym:hyaline degeneration, eosinophilic cytoplasmic change
   %lipid deposition ; MPATH:42
   %lipofuscin deposition ; MPATH:43
   %melanin deposition ; MPATH:44
   %protein deposition ; MPATH:45
    %copper deposition ; MPATH:38  % mineralisation ; MPATH:555
    %iron deposition ; MPATH:41  % mineralisation ; MPATH:555
   %uric acid deposition ; MPATH:46
   %pseudocyst ; MPATH:468
   %mucous secretions ; MPATH:547
   %mineralisation ; MPATH:555
    %calcium deposition ; MPATH:36
    %copper deposition ; MPATH:38  % protein deposition ; MPATH:45
    %iron deposition ; MPATH:41  % protein deposition ; MPATH:45
  %intracellular and extracellular depletion ; MPATH:47
   %decalcification ; MPATH:48
   %demyelination ; MPATH:49
   %glycogen depletion ; MPATH:50
   %hypocalcification ; MPATH:51
   %lipid depletion ; MPATH:52
   %osteopenia ; MPATH:53
   %osteoporosis ; MPATH:54
 %developmental and structural abnormality ; MPATH:55
  %general developmental defect ; MPATH:56
   %agenesis ; MPATH:57 ; synonym:agenesia
   %aplasia ; MPATH:58
   %branching morphogenesis defect ; MPATH:59
   %communication defect ; MPATH:60
   %curvature defect ; MPATH:61
   %cyst ; MPATH:62
   %depletion ; MPATH:63
   %developmental dysplasia ; MPATH:64
    %developmental cystic dysplasia ; MPATH:473
   %developmental hypoplasia ; MPATH:65
   %dilatation ; MPATH:66
    %ectasia ; MPATH:474
     %lymphangiectasis ; MPATH:98  % cardiovascular developmental defect ; MPATH:89
     %ductal ectasia ; MPATH:475
     %telangiectasia ; MPATH:476
   %displacement and deformity ; MPATH:67
   %diverticulum ; MPATH:68
   %fistula ; MPATH:70
   %fusion defect ; MPATH:71
   %growth acceleration ; MPATH:72
   %growth arrest ; MPATH:73
   %hamartoma ; MPATH:74
