Entrezgene ::= {
  track-info {
    geneid 1 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 14 ,
        hour 13 ,
        minute 15 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "19" } } } ,
  gene {
    locus "A1BG" ,
    desc "alpha-1-B glycoprotein" ,
    maploc "19q13.4" ,
    db {
      {
        db "MIM" ,
        tag
          id 138670 } } ,
    syn {
      "A1B" ,
      "ABG" ,
      "GAB" ,
      "HYST2477" ,
      "DKFZp686F0970" } ,
    locus-tag "HGNC:5" } ,
  prot {
    name {
      "alpha 1B-glycoprotein" ,
      "alpha-1B-glycoprotein" } } ,
  summary "The protein encoded by this gene is a plasma glycoprotein of
 unknown function. The protein shows sequence similarity to the variable
 regions of some immunoglobulin supergene family member proteins." ,
  location {
    {
      display-str "19q13.4" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 1 ,
    src-str2 "1" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000019" ,
      version 8 ,
      seqs {
        int {
          from 63548355 ,
          to 63556668 ,
          strand minus ,
          id
            gi 42406306 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_130786" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 63548355 ,
                to 63550206 ,
                strand minus ,
                id
                  gi 42406306 } ,
              int {
                from 63550530 ,
                to 63550817 ,
                strand minus ,
                id
                  gi 42406306 } ,
              int {
                from 63553547 ,
                to 63553828 ,
                strand minus ,
                id
                  gi 42406306 } ,
              int {
                from 63554568 ,
                to 63554864 ,
                strand minus ,
                id
                  gi 42406306 } ,
              int {
                from 63555460 ,
                to 63555732 ,
                strand minus ,
                id
                  gi 42406306 } ,
              int {
                from 63556105 ,
                to 63556374 ,
                strand minus ,
                id
                  gi 42406306 } ,
              int {
                from 63556469 ,
                to 63556504 ,
                strand minus ,
                id
                  gi 42406306 } ,
              int {
                from 63556581 ,
                to 63556668 ,
                strand minus ,
                id
                  gi 42406306 } } } ,
          seqs {
            whole
              gi 21071029 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_570602" ,
              version 2 ,
              genomic-coords {
                packed-int {
                  {
                    from 63550199 ,
                    to 63550206 ,
                    strand minus ,
                    id
                      gi 42406306 } ,
                  {
                    from 63550530 ,
                    to 63550817 ,
                    strand minus ,
                    id
                      gi 42406306 } ,
                  {
                    from 63553547 ,
                    to 63553828 ,
                    strand minus ,
                    id
                      gi 42406306 } ,
                  {
                    from 63554568 ,
                    to 63554864 ,
                    strand minus ,
                    id
                      gi 42406306 } ,
                  {
                    from 63555460 ,
                    to 63555732 ,
                    strand minus ,
                    id
                      gi 42406306 } ,
                  {
                    from 63556105 ,
                    to 63556374 ,
                    strand minus ,
                    id
                      gi 42406306 } ,
                  {
                    from 63556469 ,
                    to 63556504 ,
                    strand minus ,
                    id
                      gi 42406306 } ,
                  {
                    from 63556581 ,
                    to 63556614 ,
                    strand minus ,
                    id
                      gi 42406306 } } } ,
              seqs {
                whole
                  gi 21071030 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_011109" ,
      version 15 ,
      seqs {
        int {
          from 31124733 ,
          to 31133046 ,
          strand minus ,
          id
            gi 29800594 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_130786" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 31124733 ,
                to 31126584 ,
                strand minus ,
                id
                  gi 29800594 } ,
              int {
                from 31126908 ,
                to 31127195 ,
                strand minus ,
                id
                  gi 29800594 } ,
              int {
                from 31129925 ,
                to 31130206 ,
                strand minus ,
                id
                  gi 29800594 } ,
              int {
                from 31130946 ,
                to 31131242 ,
                strand minus ,
                id
                  gi 29800594 } ,
              int {
                from 31131838 ,
                to 31132110 ,
                strand minus ,
                id
                  gi 29800594 } ,
              int {
                from 31132483 ,
                to 31132752 ,
                strand minus ,
                id
                  gi 29800594 } ,
              int {
                from 31132847 ,
                to 31132882 ,
                strand minus ,
                id
                  gi 29800594 } ,
              int {
                from 31132959 ,
                to 31133046 ,
                strand minus ,
                id
                  gi 29800594 } } } ,
          seqs {
            whole
              gi 21071029 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_570602" ,
              version 2 ,
              genomic-coords {
                packed-int {
                  {
                    from 31126577 ,
                    to 31126584 ,
                    strand minus ,
                    id
                      gi 29800594 } ,
                  {
                    from 31126908 ,
                    to 31127195 ,
                    strand minus ,
                    id
                      gi 29800594 } ,
                  {
                    from 31129925 ,
                    to 31130206 ,
                    strand minus ,
                    id
                      gi 29800594 } ,
                  {
                    from 31130946 ,
                    to 31131242 ,
                    strand minus ,
                    id
                      gi 29800594 } ,
                  {
                    from 31131838 ,
                    to 31132110 ,
                    strand minus ,
                    id
                      gi 29800594 } ,
                  {
                    from 31132483 ,
                    to 31132752 ,
                    strand minus ,
                    id
                      gi 29800594 } ,
                  {
                    from 31132847 ,
                    to 31132882 ,
                    strand minus ,
                    id
                      gi 29800594 } ,
                  {
                    from 31132959 ,
                    to 31132992 ,
                    strand minus ,
                    id
                      gi 29800594 } } } ,
              seqs {
                whole
                  gi 21071030 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086907" ,
      version 1 ,
      seqs {
        int {
          from 8163589 ,
          to 8172398 ,
          strand minus ,
          id
            gi 51475048 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_130786" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 8163589 ,
                to 8165440 ,
                strand minus ,
                id
                  gi 51475048 } ,
              int {
                from 8165763 ,
                to 8166050 ,
                strand minus ,
                id
                  gi 51475048 } ,
              int {
                from 8169274 ,
                to 8169555 ,
                strand minus ,
                id
                  gi 51475048 } ,
              int {
                from 8170297 ,
                to 8170593 ,
                strand minus ,
                id
                  gi 51475048 } ,
              int {
                from 8171190 ,
                to 8171462 ,
                strand minus ,
                id
                  gi 51475048 } ,
              int {
                from 8171835 ,
                to 8172104 ,
                strand minus ,
                id
                  gi 51475048 } ,
              int {
                from 8172199 ,
                to 8172234 ,
                strand minus ,
                id
                  gi 51475048 } ,
              int {
                from 8172311 ,
                to 8172398 ,
                strand minus ,
                id
                  gi 51475048 } } } ,
          seqs {
            whole
              gi 21071029 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_570602" ,
              version 2 ,
              genomic-coords {
                packed-int {
                  {
                    from 8165433 ,
                    to 8165440 ,
                    strand minus ,
                    id
                      gi 51475048 } ,
                  {
                    from 8165763 ,
                    to 8166050 ,
                    strand minus ,
                    id
                      gi 51475048 } ,
                  {
                    from 8169274 ,
                    to 8169555 ,
                    strand minus ,
                    id
                      gi 51475048 } ,
                  {
                    from 8170297 ,
                    to 8170593 ,
                    strand minus ,
                    id
                      gi 51475048 } ,
                  {
                    from 8171190 ,
                    to 8171462 ,
                    strand minus ,
                    id
                      gi 51475048 } ,
                  {
                    from 8171835 ,
                    to 8172104 ,
                    strand minus ,
                    id
                      gi 51475048 } ,
                  {
                    from 8172199 ,
                    to 8172234 ,
                    strand minus ,
                    id
                      gi 51475048 } ,
                  {
                    from 8172311 ,
                    to 8172344 ,
                    strand minus ,
                    id
                      gi 51475048 } } } ,
              seqs {
                whole
                  gi 21071030 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "A1BG" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "alpha-1-B glycoprotein" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "GOA" ,
          url "http://www.ebi.ac.uk/GOA/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 3458201 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5554 } ,
                  anchor "molecular_function unknown" ,
                  post-text "evidence: ND" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4 } ,
                  anchor "biological_process unknown" ,
                  post-text "evidence: ND" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 3458201 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5576 } ,
                  anchor "extracellular region" ,
                  post-text "evidence: IDA" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 11167 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=19&
MAPS=genes-r-org/rat-chr/human%3A19,genes-r-org/mouse-chr/human%3A19,genes-r-o
rg/human-chr19&query=e%3A1[id]+AND+gene[obj_type]&QSTR=a1bg&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 5 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 15461460 ,
        pmid 15221005 ,
        pmid 14702039 ,
        pmid 12477932 ,
        pmid 8889549 ,
        pmid 3610142 ,
        pmid 3458201 ,
        pmid 2591067 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 89991 } ,
              anchor "SHGC-67307" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "RH80032" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH86145" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 152074 } ,
              anchor "D11S2921" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "GDB:461809" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 155756 } ,
              anchor "D10S16" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "D10S23" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "GDB:193809" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_130786" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 21071029 } ,
              anchor "NM_130786" } } ,
          seqs {
            whole
              gi 21071029 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_570602" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 21071030 } ,
                  anchor "NP_570602" ,
                  post-text "alpha 1B-glycoprotein" } } ,
              seqs {
                whole
                  gi 21071030 } ,
              comment {
                {
                  type other ,
                  heading "Consensus CDS (CCDS)" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "CCDS" ,
                        tag
                          str "CCDS12976.1" } ,
                      anchor "CCDS12976.1" } } } ,
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 21071030 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 365 } ,
                          anchor "smart00408: IGc2; Immunoglobulin C-2 Type" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 223 - 282  Blast Score: 103" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "AF414429,AK055885,AK056201" } ,
                  anchor "AF414429,AK055885,AK056201" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "AC010642" ,
          version 5 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 9929687 } ,
              anchor "AC010642" } } ,
          seqs {
            int {
              from 41119 ,
              to 43581 ,
              strand plus ,
              id
                gi 9929687 } } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AB073611" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 51555784 } ,
              anchor "AB073611" } } ,
          seqs {
            whole
              gi 51555784 } ,
          products {
            {
              type peptide ,
              accession "BAD38648" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 51555785 } ,
                  anchor "BAD38648" } } ,
              seqs {
                whole
                  gi 51555785 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AF414429" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 15778555 } ,
              anchor "AF414429" } } ,
          seqs {
            whole
              gi 15778555 } ,
          products {
            {
              type peptide ,
              accession "AAL07469" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 15778556 } ,
                  anchor "AAL07469" } } ,
              seqs {
                whole
                  gi 15778556 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK055885" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 16550723 } ,
              anchor "AK055885" } } ,
          seqs {
            whole
              gi 16550723 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK056201" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 16551539 } ,
              anchor "AK056201" } } ,
          seqs {
            whole
              gi 16551539 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC035719" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 23273475 } ,
              anchor "BC035719" } } ,
          seqs {
            whole
              gi 23273475 } ,
          products {
            {
              type peptide ,
              accession "AAH35719" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 23273476 } ,
                  anchor "AAH35719" } } ,
              seqs {
                whole
                  gi 23273476 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BX537419" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 31873339 } ,
              anchor "BX537419" } } ,
          seqs {
            whole
              gi 31873339 } ,
          products {
            {
              type peptide ,
              accession "CAD97661" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 31873340 } ,
                  anchor "CAD97661" } } ,
              seqs {
                whole
                  gi 31873340 } } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "P04217" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 46577680 } ,
                  anchor "P04217" } } ,
              seqs {
                whole
                  gi 46577680 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "1" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_011109.15&gene=A1BG&lid=1&from=31124734&to=31133047" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "1" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96
06&contig=NT_011109.15&gene=A1BG&lid=1" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Hs.529161" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Hs.529161" } ,
              anchor "Hs.529161" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=52
9161" } } } ,
        {
          type comment ,
          text "MIM" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  str "138670" } ,
              anchor "138670" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "1" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
1[loc]&TAXID=9606" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "AceView" ,
                tag
                  id 1 } ,
              anchor "AceView" ,
              url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l
ocusid&org=9606&l=1" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:119638" } } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=AK055
885" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
AK055885" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGC" ,
                tag
                  str "BC035719" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC035719" } } } } } ,
    {
      type generif ,
      text "A1BG-cysteine-rich secretory protein 3 complex displays a similar
 function in protecting the circulation from a potentially harmful effect of
 free CRISP-3" ,
      version 0 ,
      refs {
        pmid 15461460 } ,
      create-date
        str "Nov  6 2004 10:01AM" ,
      update-date
        str "Nov  6 2004  3:27PM" } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 1 } ,
    {
      db "MIM" ,
      tag
        id 138670 } } ,
  xtra-index-terms {
    "LOC1" } }
Entrezgene ::= {
  track-info {
    geneid 2 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 14 ,
        hour 13 ,
        minute 15 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "12" } } } ,
  gene {
    locus "A2M" ,
    desc "alpha-2-macroglobulin" ,
    maploc "12p13.3-p12.3" ,
    db {
      {
        db "MIM" ,
        tag
          id 103950 } } ,
    syn {
      "FWP007" ,
      "S863-7" ,
      "DKFZp779B086" } ,
    locus-tag "HGNC:7" } ,
  prot {
    name {
      "alpha-2-macroglobulin" } } ,
  summary "Alpha-2-macroglobulin is a protease inhibitor and cytokine
 transporter. It inhibits many proteases, including trypsin, thrombin and
 collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability
 to mediate the clearance and degradation of A-beta, the major component of
 beta-amyloid deposits." ,
  location {
    {
      display-str "12p13.3-p12.3" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 2 ,
    src-str2 "2" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000012" ,
      version 9 ,
      seqs {
        int {
          from 9111576 ,
          to 9159755 ,
          strand minus ,
          id
            gi 51511728 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000014" ,
          version 3 ,
          genomic-coords {
            mix {
              int {
                from 9111576 ,
                to 9111701 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9112045 ,
                to 9112086 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9112602 ,
                to 9112704 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9113607 ,
                to 9113675 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9114350 ,
                to 9114440 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9116221 ,
                to 9116348 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9116515 ,
                to 9116733 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9118422 ,
                to 9118645 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9120618 ,
                to 9120798 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9121208 ,
                to 9121282 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9121563 ,
                to 9121719 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9123106 ,
                to 9123193 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9123501 ,
                to 9123677 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9123956 ,
                to 9124039 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9133062 ,
                to 9133113 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9133764 ,
                to 9133885 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9134218 ,
                to 9134344 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9135063 ,
                to 9135291 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9137327 ,
                to 9137441 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9138835 ,
                to 9138946 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9139401 ,
                to 9139562 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9142469 ,
                to 9142618 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9143243 ,
                to 9143385 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9145006 ,
                to 9145069 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9145309 ,
                to 9145536 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9148101 ,
                to 9148262 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9150098 ,
                to 9150207 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9150353 ,
                to 9150467 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9151386 ,
                to 9151506 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9153183 ,
                to 9153267 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9153729 ,
                to 9153897 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9154176 ,
                to 9154196 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9156021 ,
                to 9156073 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9156239 ,
                to 9156398 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9157222 ,
                to 9157405 ,
                strand minus ,
                id
                  gi 51511728 } ,
              int {
                from 9159626 ,
                to 9159755 ,
                strand minus ,
                id
                  gi 51511728 } } } ,
          seqs {
            whole
              gi 6226959 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              label "precursor" ,
              accession "NP_000005" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 9111685 ,
                    to 9111701 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9112045 ,
                    to 9112086 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9112602 ,
                    to 9112704 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9113607 ,
                    to 9113675 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9114350 ,
                    to 9114440 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9116221 ,
                    to 9116348 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9116515 ,
                    to 9116733 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9118422 ,
                    to 9118645 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9120618 ,
                    to 9120798 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9121208 ,
                    to 9121282 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9121563 ,
                    to 9121719 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9123106 ,
                    to 9123193 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9123501 ,
                    to 9123677 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9123956 ,
                    to 9124039 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9133062 ,
                    to 9133113 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9133764 ,
                    to 9133885 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9134218 ,
                    to 9134344 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9135063 ,
                    to 9135291 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9137327 ,
                    to 9137441 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9138835 ,
                    to 9138946 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9139401 ,
                    to 9139562 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9142469 ,
                    to 9142618 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9143243 ,
                    to 9143385 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9145006 ,
                    to 9145069 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9145309 ,
                    to 9145536 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9148101 ,
                    to 9148262 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9150098 ,
                    to 9150207 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9150353 ,
                    to 9150467 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9151386 ,
                    to 9151506 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9153183 ,
                    to 9153267 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9153729 ,
                    to 9153897 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9154176 ,
                    to 9154196 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9156021 ,
                    to 9156073 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9156239 ,
                    to 9156398 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9157222 ,
                    to 9157405 ,
                    strand minus ,
                    id
                      gi 51511728 } ,
                  {
                    from 9159626 ,
                    to 9159711 ,
                    strand minus ,
                    id
                      gi 51511728 } } } ,
              seqs {
                whole
                  gi 4557225 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_009714" ,
      version 16 ,
      seqs {
        int {
          from 1979283 ,
          to 2027462 ,
          strand minus ,
          id
            gi 37543832 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000014" ,
          version 3 ,
          genomic-coords {
            mix {
              int {
                from 1979283 ,
                to 1979408 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1979752 ,
                to 1979793 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1980309 ,
                to 1980411 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1981314 ,
                to 1981382 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1982057 ,
                to 1982147 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1983928 ,
                to 1984055 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1984222 ,
                to 1984440 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1986129 ,
                to 1986352 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1988325 ,
                to 1988505 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1988915 ,
                to 1988989 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1989270 ,
                to 1989426 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1990813 ,
                to 1990900 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1991208 ,
                to 1991384 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 1991663 ,
                to 1991746 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2000769 ,
                to 2000820 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2001471 ,
                to 2001592 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2001925 ,
                to 2002051 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2002770 ,
                to 2002998 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2005034 ,
                to 2005148 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2006542 ,
                to 2006653 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2007108 ,
                to 2007269 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2010176 ,
                to 2010325 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2010950 ,
                to 2011092 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2012713 ,
                to 2012776 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2013016 ,
                to 2013243 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2015808 ,
                to 2015969 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2017805 ,
                to 2017914 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2018060 ,
                to 2018174 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2019093 ,
                to 2019213 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2020890 ,
                to 2020974 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2021436 ,
                to 2021604 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2021883 ,
                to 2021903 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2023728 ,
                to 2023780 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2023946 ,
                to 2024105 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2024929 ,
                to 2025112 ,
                strand minus ,
                id
                  gi 37543832 } ,
              int {
                from 2027333 ,
                to 2027462 ,
                strand minus ,
                id
                  gi 37543832 } } } ,
          seqs {
            whole
              gi 6226959 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              label "precursor" ,
              accession "NP_000005" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 1979392 ,
                    to 1979408 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1979752 ,
                    to 1979793 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1980309 ,
                    to 1980411 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1981314 ,
                    to 1981382 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1982057 ,
                    to 1982147 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1983928 ,
                    to 1984055 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1984222 ,
                    to 1984440 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1986129 ,
                    to 1986352 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1988325 ,
                    to 1988505 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1988915 ,
                    to 1988989 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1989270 ,
                    to 1989426 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1990813 ,
                    to 1990900 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1991208 ,
                    to 1991384 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 1991663 ,
                    to 1991746 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2000769 ,
                    to 2000820 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2001471 ,
                    to 2001592 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2001925 ,
                    to 2002051 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2002770 ,
                    to 2002998 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2005034 ,
                    to 2005148 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2006542 ,
                    to 2006653 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2007108 ,
                    to 2007269 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2010176 ,
                    to 2010325 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2010950 ,
                    to 2011092 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2012713 ,
                    to 2012776 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2013016 ,
                    to 2013243 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2015808 ,
                    to 2015969 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2017805 ,
                    to 2017914 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2018060 ,
                    to 2018174 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2019093 ,
                    to 2019213 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2020890 ,
                    to 2020974 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2021436 ,
                    to 2021604 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2021883 ,
                    to 2021903 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2023728 ,
                    to 2023780 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2023946 ,
                    to 2024105 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2024929 ,
                    to 2025112 ,
                    strand minus ,
                    id
                      gi 37543832 } ,
                  {
                    from 2027333 ,
                    to 2027418 ,
                    strand minus ,
                    id
                      gi 37543832 } } } ,
              seqs {
                whole
                  gi 4557225 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086792" ,
      version 1 ,
      seqs {
        int {
          from 4173171 ,
          to 4221277 ,
          strand minus ,
          id
            gi 51471135 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000014" ,
          version 3 ,
          genomic-coords {
            mix {
              int {
                from 4173171 ,
                to 4173296 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4173640 ,
                to 4173681 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4174197 ,
                to 4174299 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4175201 ,
                to 4175269 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4175944 ,
                to 4176034 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4177816 ,
                to 4177943 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4178110 ,
                to 4178328 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4180017 ,
                to 4180240 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4182213 ,
                to 4182393 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4182803 ,
                to 4182877 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4183158 ,
                to 4183314 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4184702 ,
                to 4184789 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4185097 ,
                to 4185273 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4185552 ,
                to 4185635 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4194661 ,
                to 4194712 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4195363 ,
                to 4195484 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4195817 ,
                to 4195943 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4196662 ,
                to 4196890 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4198926 ,
                to 4199040 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4200364 ,
                to 4200475 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4200930 ,
                to 4201091 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4203997 ,
                to 4204146 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4204771 ,
                to 4204913 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4206534 ,
                to 4206597 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4206837 ,
                to 4207064 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4209629 ,
                to 4209790 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4211627 ,
                to 4211736 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4211882 ,
                to 4211996 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4212916 ,
                to 4213036 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4214705 ,
                to 4214789 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4215251 ,
                to 4215419 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4215698 ,
                to 4215718 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4217543 ,
                to 4217595 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4217761 ,
                to 4217920 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4218744 ,
                to 4218927 ,
                strand minus ,
                id
                  gi 51471135 } ,
              int {
                from 4221148 ,
                to 4221277 ,
                strand minus ,
                id
                  gi 51471135 } } } ,
          seqs {
            whole
              gi 6226959 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              label "precursor" ,
              accession "NP_000005" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 4173280 ,
                    to 4173296 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4173640 ,
                    to 4173681 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4174197 ,
                    to 4174299 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4175201 ,
                    to 4175269 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4175944 ,
                    to 4176034 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4177816 ,
                    to 4177943 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4178110 ,
                    to 4178328 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4180017 ,
                    to 4180240 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4182213 ,
                    to 4182393 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4182803 ,
                    to 4182877 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4183158 ,
                    to 4183314 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4184702 ,
                    to 4184789 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4185097 ,
                    to 4185273 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4185552 ,
                    to 4185635 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4194661 ,
                    to 4194712 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4195363 ,
                    to 4195484 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4195817 ,
                    to 4195943 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4196662 ,
                    to 4196890 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4198926 ,
                    to 4199040 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4200364 ,
                    to 4200475 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4200930 ,
                    to 4201091 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4203997 ,
                    to 4204146 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4204771 ,
                    to 4204913 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4206534 ,
                    to 4206597 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4206837 ,
                    to 4207064 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4209629 ,
                    to 4209790 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4211627 ,
                    to 4211736 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4211882 ,
                    to 4211996 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4212916 ,
                    to 4213036 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4214705 ,
                    to 4214789 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4215251 ,
                    to 4215419 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4215698 ,
                    to 4215718 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4217543 ,
                    to 4217595 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4217761 ,
                    to 4217920 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4218744 ,
                    to 4218927 ,
                    strand minus ,
                    id
                      gi 51471135 } ,
                  {
                    from 4221148 ,
                    to 4221233 ,
                    strand minus ,
                    id
                      gi 51471135 } } } ,
              seqs {
                whole
                  gi 4557225 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "A2M" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "alpha-2-macroglobulin" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "GOA" ,
          url "http://www.ebi.ac.uk/GOA/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 11435418 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 19899 } ,
                  anchor "enzyme binding" ,
                  post-text "evidence: IPI" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9714181 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 19966 } ,
                  anchor "interleukin-1 binding" ,
                  post-text "evidence: IDA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 10880251 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 19959 } ,
                  anchor "interleukin-8 binding" ,
                  post-text "evidence: IPI" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8320 } ,
                  anchor "protein carrier activity" ,
                  post-text "evidence: NR" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4867 } ,
                  anchor "serine-type endopeptidase inhibitor activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9714181 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 43120 } ,
                  anchor "tumor necrosis factor binding" ,
                  post-text "evidence: IDA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 17114 } ,
                  anchor "wide-spectrum protease inhibitor activity" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6886 } ,
                  anchor "intracellular protein transport" ,
                  post-text "evidence: NR" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 51260 } ,
                  anchor "protein homooligomerization" ,
                  post-text "evidence: NAS" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 14718574 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5576 } ,
                  anchor "extracellular region" ,
                  post-text "evidence: NAS" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 37248 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=12&
MAPS=genes-r-org/rat-chr/human%3A12,genes-r-org/mouse-chr/human%3A12,genes-r-o
rg/human-chr12&query=e%3A2[id]+AND+gene[obj_type]&QSTR=a2m&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 7 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 15511627 ,
        pmid 15023809 ,
        pmid 14760718 ,
        pmid 14718574 ,
        pmid 14715656 ,
        pmid 14678766 ,
        pmid 14675603 ,
        pmid 14637088 ,
        pmid 14506912 ,
        pmid 12966032 ,
        pmid 12755687 ,
        pmid 12755614 ,
        pmid 12631277 ,
        pmid 12477932 ,
        pmid 12221172 ,
        pmid 12194978 ,
        pmid 12175343 ,
        pmid 12062545 ,
        pmid 12042276 ,
        pmid 12015318 ,
        pmid 11916201 ,
        pmid 11910179 ,
        pmid 11901360 ,
        pmid 11823454 ,
        pmid 11811950 ,
        pmid 11435418 ,
        pmid 11162584 ,
        pmid 11100124 ,
        pmid 11023837 ,
        pmid 10880251 ,
        pmid 10731476 ,
        pmid 10714547 ,
        pmid 10652313 ,
        pmid 10373500 ,
        pmid 9831625 ,
        pmid 9724081 ,
        pmid 9714181 ,
        pmid 8583572 ,
        pmid 7680268 ,
        pmid 7533769 ,
        pmid 7533162 ,
        pmid 7519849 ,
        pmid 6191979 ,
        pmid 6153632 ,
        pmid 3289986 ,
        pmid 2581245 ,
        pmid 2476070 ,
        pmid 2460294 ,
        pmid 2459995 ,
        pmid 2408344 ,
        pmid 1707161 ,
        pmid 1697852 ,
        pmid 1370808 ,
        pmid 1281457 ,
        pmid 89758 } } ,
    {
      type comment ,
      heading "Phenotypes" ,
      version 0 ,
      comment {
        {
          type phenotype ,
          text "Alzheimer disease, susceptibility to" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  id 103950 } ,
              anchor "MIM: 103950" } } } ,
        {
          type phenotype ,
          text "Emphysema due to alpha-2-macroglobulin deficiency" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  id 103950 } ,
              anchor "MIM: 103950" } } } } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 25036 } ,
              anchor "RH1601" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "RH44109" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "stSG1293" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 40245 } ,
              anchor "SGC31674" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "EST130345" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH52474" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "WI-219" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 46849 } ,
              anchor "RH11157" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "RH44108" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "stSG1290R" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 95143 } ,
              anchor "G44356" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "WIAF-1430-STS" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 147540 } ,
              anchor "NoName" ,
              post-text "(e-PCR)" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 151442 } ,
              anchor "NoName" ,
              post-text "(e-PCR)" } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_000014" ,
          version 3 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 6226959 } ,
              anchor "NM_000014" } } ,
          seqs {
            whole
              gi 6226959 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_000005" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 4557225 } ,
                  anchor "NP_000005" ,
                  post-text "alpha-2-macroglobulin precursor" } } ,
              seqs {
                whole
                  gi 4557225 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 4557225 } ,
                      pre-text "(2)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5952 } ,
                          anchor "pfam00207: A2M; Alpha-2-macroglobulin family" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 725 - 1463  Blast Score: 2322" ,
                          version 0 } } } ,
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 25832 } ,
                          anchor "pfam01835: A2M_N; Alpha-2-macroglobulin
 family N-terminal region" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 21 - 628  Blast Score: 1948" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "M11313" } ,
                  anchor "M11313" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF349032" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 13661813 } ,
              anchor "AF349032" } } ,
          seqs {
            whole
              gi 13661813 } ,
          products {
            {
              type peptide ,
              accession "AAK38109" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 13661814 } ,
                  anchor "AAK38109" } } ,
              seqs {
                whole
                  gi 13661814 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF349033" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 13661815 } ,
              anchor "AF349033" } } ,
          seqs {
            whole
              gi 13661815 } ,
          products {
            {
              type peptide ,
              accession "AAK38110" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 13661816 } ,
                  anchor "AAK38110" } } ,
              seqs {
                whole
                  gi 13661816 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "X68728" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 450521 } ,
              anchor "X68728" } } ,
          seqs {
            whole
              gi 450521 } ,
          products {
            {
              type peptide ,
              accession "CAA48670" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 825615 } ,
                  anchor "CAA48670" } } ,
              seqs {
                whole
                  gi 825615 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "Z11711" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 24760 } ,
              anchor "Z11711" } } ,
          seqs {
            whole
              gi 24760 } ,
          products {
            {
              type peptide ,
              accession "CAA77774" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 24761 } ,
                  anchor "CAA77774" } } ,
              seqs {
                whole
                  gi 24761 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AB209614" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 62088807 } ,
              anchor "AB209614" } } ,
          seqs {
            whole
              gi 62088807 } ,
          products {
            {
              type peptide ,
              accession "BAD92851" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 62088808 } ,
                  anchor "BAD92851" } } ,
              seqs {
                whole
                  gi 62088808 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AF109189" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 33337723 } ,
              anchor "AF109189" } } ,
          seqs {
            whole
              gi 33337723 } ,
          products {
            {
              type peptide ,
              accession "AAQ13498" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 33337724 } ,
                  anchor "AAQ13498" } } ,
              seqs {
                whole
                  gi 33337724 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AY591530" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 46812314 } ,
              anchor "AY591530" } } ,
          seqs {
            whole
              gi 46812314 } ,
          products {
            {
              type peptide ,
              accession "AAT02228" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 46812315 } ,
                  anchor "AAT02228" } } ,
              seqs {
                whole
                  gi 46812315 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC026246" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 45708660 } ,
              anchor "BC026246" } } ,
          seqs {
            whole
              gi 45708660 } ,
          products {
            {
              type peptide ,
              accession "AAH26246" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 45708661 } ,
                  anchor "AAH26246" } } ,
              seqs {
                whole
                  gi 45708661 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC040071" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 25303945 } ,
              anchor "BC040071" } } ,
          seqs {
            whole
              gi 25303945 } ,
          products {
            {
              type peptide ,
              accession "AAH40071" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 25303946 } ,
                  anchor "AAH40071" } } ,
              seqs {
                whole
                  gi 25303946 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BX647329" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 34366357 } ,
              anchor "BX647329" } } ,
          seqs {
            whole
              gi 34366357 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "CR749334" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 51476395 } ,
              anchor "CR749334" } } ,
          seqs {
            whole
              gi 51476395 } ,
          products {
            {
              type peptide ,
              accession "CAH18188" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 51476396 } ,
                  anchor "CAH18188" } } ,
              seqs {
                whole
                  gi 51476396 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "M11313" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 177869 } ,
              anchor "M11313" } } ,
          seqs {
            whole
              gi 177869 } ,
          products {
            {
              type peptide ,
              accession "AAA51551" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 177870 } ,
                  anchor "AAA51551" } } ,
              seqs {
                whole
                  gi 177870 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "M36501" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 177871 } ,
              anchor "M36501" } } ,
          seqs {
            whole
              gi 177871 } ,
          products {
            {
              type peptide ,
              accession "AAA51552" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 177872 } ,
                  anchor "AAA51552" } } ,
              seqs {
                whole
                  gi 177872 } } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "P01023" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 112911 } ,
                  anchor "P01023" } } ,
              seqs {
                whole
                  gi 112911 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "2" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_009714.16&gene=A2M&lid=2&from=1979284&to=2027463" } } } ,
        {
          type comment ,
          version 0 ,
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            {
              src {
                db "ModelMaker" ,
                tag
                  str "2" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96
06&contig=NT_009714.16&gene=A2M&lid=2" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Hs.212838" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Hs.212838" } ,
              anchor "Hs.212838" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=21
2838" } } } ,
        {
          type comment ,
          text "MIM" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  str "103950" } ,
              anchor "103950" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "2" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
2[loc]&TAXID=9606" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "AceView" ,
                tag
                  id 2 } ,
              anchor "AceView" ,
              url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l
ocusid&org=9606&l=2" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:119639" } } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HGMD" ,
                tag
                  str "" } ,
              url "http://www.uwcm.ac.uk/uwcm/mg/search/119639.html" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=CR749
334" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
CR749334" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "KEGG" ,
                tag
                  str "" } ,
              url "http://www.genome.ad.jp/dbget-bin/www_bget?hsa:2" } } } ,
        {
          type comment ,
          text "PharmGKB" ,
          version 0 ,
          source {
            {
              src {
                db "PharmGKB" ,
                tag
                  str "PA24357" } ,
              anchor "PA24357" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGC" ,
                tag
                  str "BC040071" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC040071" } } } } } ,
    {
      type comment ,
      heading "Pathways" ,
      version 0 ,
      comment {
        {
          type comment ,
          text "KEGG pathway: Alzheimer's disease" ,
          version 0 ,
          source {
            {
              src {
                db "05010" ,
                tag
                  str "05010" } ,
              anchor "05010" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa05010+2" } } } ,
        {
          type comment ,
          text "KEGG pathway: Coagulation cascade" ,
          version 0 ,
          source {
            {
              src {
                db "04610" ,
                tag
                  str "04610" } ,
              anchor "04610" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa04610+2" } } } ,
        {
          type comment ,
          text "KEGG pathway: Complement and coagulation cascades" ,
          version 0 ,
          source {
            {
              src {
                db "04610" ,
                tag
                  str "04610" } ,
              anchor "04610" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa04610+2" } } } ,
        {
          type comment ,
          text "Reactome: Hemostasis" ,
          version 0 ,
          source {
            {
              anchor "49292" ,
              url "http://www.reactome.org/cgi-bin/link?SOURCE=UniProt&ID=P010
23" } } } } } ,
    {
      type generif ,
      text "an important involvement of alpha2M in regulation of increased
 proteolytic activity occurring in multiple sclerosis disease" ,
      version 0 ,
      refs {
        pmid 15511627 } ,
      create-date
        str "Dec 18 2004 10:01AM" ,
      update-date
        str "Dec 18 2004  1:19PM" } ,
    {
      type generif ,
      text "alpha2-macroglobulin inhibits human pepsin and gastricsin" ,
      version 0 ,
      refs {
        pmid 14506912 } ,
      create-date
        str "Oct  7 2003 12:00AM" ,
      update-date
        str "Jul  7 2004  1:36PM" } ,
    {
      type generif ,
      text "There is a significant genetic association of the 5 bp deletion
 and two novel polymorphisms in alpha-2-macroglobulin alpha-2-macroglobulin
 precursor with AD" ,
      version 0 ,
      refs {
        pmid 12966032 } ,
      create-date
        str "Jun 27 2004  5:41PM" ,
      update-date
        str "Jun 27 2004  6:18PM" } ,
    {
      type generif ,
      text "Alpha2-macroglobulin is a substrate and an endogenous inhibitor
 for ADAMTS-4 and ADAMTS-5" ,
      version 0 ,
      refs {
        pmid 14715656 } ,
      create-date
        str "Jun 14 2004  4:41PM" ,
      update-date
        str "Jun 14 2004  5:44PM" } ,
    {
      type generif ,
      text "A2M-D allele played a weak Alzheimer disease protective role, and
 APOE-E4 and A2M-G alleles might act synergistically in Alzheimer disease risk
 for mainland Han Chinese." ,
      version 0 ,
      refs {
        pmid 14675603 } ,
      create-date
        str "Feb 17 2004 12:00AM" ,
      update-date
        str "Apr 13 2004  1:35PM" } ,
    {
      type generif ,
      text "Plasma from patients homozygous for the intronic deletion (DD)
 showed normal alpha(2)M subunit size, conformation, and proteinase inhibitory
 activity. Plasma alpha(2)M from two DD patients showed markedly increased
 TGF-beta1 binding." ,
      version 0 ,
      refs {
        pmid 14678766 } ,
      create-date
        str "Jan 20 2004 12:00AM" ,
      update-date
        str "Mar  7 2004  7:01AM" } ,
    {
      type generif ,
      text "The presence of MPO-G/G and A2M-Val/Val genotypes synergistically
 increased the risk of AD (OR, 25.5; 95% CI, 4.65-139.75)." ,
      version 0 ,
      refs {
        pmid 15023809 } ,
      create-date
        str "Mar 25 2004 12:00AM" ,
      update-date
        str "Apr 18 2004  7:02AM" } ,
    {
      type generif ,
      text "alpha2-M deletion polymorphism is probably not associated with
 functional deficiencies important in Alzheimer's disease pathology" ,
      version 0 ,
      refs {
        pmid 14637088 } ,
      create-date
        str "Dec 31 2003 12:00AM" ,
      update-date
        str "Jan 11 2004  7:02AM" } ,
    {
      type generif ,
      text "FGF-2 and this protein interact at specific binding sites,
 involving different FGF-2 sequences." ,
      version 0 ,
      refs {
        pmid 12755687 } ,
      create-date
        str "Sep  7 2003 12:00AM" ,
      update-date
        str "Sep 28 2003  7:01AM" } ,
    {
      type generif ,
      text "alpha(2)M-derived peptides target the receptor-binding sequence in
 TGF-beta" ,
      version 0 ,
      refs {
        pmid 12755614 } ,
      create-date
        str "Jun 25 2003 12:00AM" ,
      update-date
        str "Jul  6 2003  7:01AM" } ,
    {
      type generif ,
      text "These results suggest the possible involvement of cathepsin E in
 disruption of the structural and functional integrity of alpha
 2-macroglobulin in the endolysosome system." ,
      version 0 ,
      refs {
        pmid 12631277 } ,
      create-date
        str "May  8 2003 12:00AM" ,
      update-date
        str "May 11 2003  7:01AM" } ,
    {
      type generif ,
      text "Alpha 2-macroglobulin enhances prothrombin activation and thrombin
 potential by inhibiting the anticoagulant protein C/protein S system in cord
 and adult plasma." ,
      version 0 ,
      refs {
        pmid 12062545 } ,
      create-date
        str "Feb  6 2003 12:00AM" ,
      update-date
        str "Aug 17 2003  7:01AM" } ,
    {
      type generif ,
      text "relationship between serum VEGF levels, alpha(2)M levels and the
 development of OHSS in hyperstimulated subjects undergoing IVF" ,
      version 0 ,
      refs {
        pmid 12042276 } ,
      create-date
        str "Dec 16 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:00AM" } ,
    {
      type generif ,
      text "Genetic association of alpha2-macroglobulin polymorphisms with
 Alzheimer's disease" ,
      version 0 ,
      refs {
        pmid 12221172 } ,
      create-date
        str "Sep 27 2002 12:00AM" ,
      update-date
        str "Oct  7 2002  8:10AM" } ,
    {
      type generif ,
      text "Genetic association of argyrophilic grain disease with
 polymorphisms in alpha-2 macroglobulin." ,
      version 0 ,
      refs {
        pmid 12175343 } ,
      create-date
        str "Sep 24 2002 12:00AM" ,
      update-date
        str "Oct  7 2002  8:10AM" } ,
    {
      type generif ,
      text "The three-dimensional structure of the dimer reveals its
 structural organization in the tetrameric native and chymotrypsin alpha
 2-macroglobulin complexes." ,
      version 0 ,
      refs {
        pmid 12015318 } ,
      create-date
        str "Sep  5 2002 12:00AM" ,
      update-date
        str "Sep 23 2002  6:27AM" } ,
    {
      type generif ,
      text "has an important role in the AD-specific neurodegenerative process
 but its exon 24 Val-1000-Ile polymorphism is not likely to be associated with
 late-onset sporadic AD in the Hungarian population" ,
      version 0 ,
      refs {
        pmid 11901360 } ,
      create-date
        str "Aug  6 2002 12:00AM" ,
      update-date
        str "Aug 28 2002  6:15PM" } ,
    {
      type generif ,
      text "REVIEW: binds and neutralizes alfimeprase, which has direct
 proteolytic activity against the fibrinogen Aalpha chain" ,
      version 0 ,
      refs {
        pmid 11910179 } ,
      create-date
        str "Jun 12 2002 12:00AM" ,
      update-date
        str "Sep  7 2003  7:01AM" } ,
    {
      type generif ,
      text "distinct binding sites mediate interaction with beta-amyloid
 peptide and growth factors" ,
      version 0 ,
      refs {
        pmid 11823454 } ,
      create-date
        str "May  4 2002 12:00AM" ,
      update-date
        str "May 18 2002  6:08AM" } ,
    {
      type generif ,
      text "Differential binding to ldl receptor related protein" ,
      version 0 ,
      refs {
        pmid 11811950 } ,
      create-date
        str "Feb 14 2002 12:00AM" ,
      update-date
        str "Mar  4 2002  7:46AM" } ,
    {
      type generif ,
      heading "HIV-1 protein interactions" ,
      version 0 ,
      comment {
        {
          type generif ,
          text "Binding of HIV-1 Tat to LRP inhibits neuronal binding, uptake
 and degradation of physiological ligands for LRP, including
 alpha2-macroglobulin, apolipoprotein E4, amyloid precursor and amyloid
 beta-protein" ,
          version 0 ,
          refs {
            pmid 11100124 } ,
          comment {
            {
              type comment ,
              label "Tat" ,
              accession "NP_057853" ,
              version 1 ,
              source {
                {
                  src {
                    db "GeneID" ,
                    tag
                      id 155871 } } } } ,
            {
              type comment ,
              accession "NP_000005" ,
              version 1 } } ,
          create-date
            str "May 11 2004 12:48PM" ,
          update-date
            str "May 11 2004  1:10PM" } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 2 } ,
    {
      db "MIM" ,
      tag
        id 103950 } } ,
  xtra-index-terms {
    "LOC2" } ,
  xtra-properties {
    {
      tag "PROP" ,
      value "phenotype" } } }
Entrezgene ::= {
  track-info {
    geneid 3 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 9 ,
        second 0 } } ,
  type pseudo ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "12" } } } ,
  gene {
    locus "A2MP" ,
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    maploc "12p13.3-p12.3" ,
    locus-tag "HGNC:8" } ,
  location {
    {
      display-str "12p13.3-p12.3" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 3 ,
    src-str2 "3" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000012" ,
      version 9 ,
      seqs {
        int {
          from 9275468 ,
          to 9278174 ,
          strand minus ,
          id
            gi 51511728 ,
          fuzz-from
            lim lt ,
          fuzz-to
            lim gt } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_009714" ,
      version 16 ,
      seqs {
        int {
          from 2143175 ,
          to 2145881 ,
          strand minus ,
          id
            gi 37543832 ,
          fuzz-from
            lim lt ,
          fuzz-to
            lim gt } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086792" ,
      version 1 ,
      seqs {
        int {
          from 4337316 ,
          to 4340022 ,
          strand minus ,
          id
            gi 51471135 ,
          fuzz-from
            lim lt ,
          fuzz-to
            lim gt } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NG_001067" ,
      version 1 ,
      seqs {
        int {
          from 176 ,
          to 2880 ,
          strand plus ,
          id
            gi 20270626 ,
          fuzz-from
            lim lt ,
          fuzz-to
            lim gt } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "A2MP" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "alpha-2-macroglobulin pseudogene" ,
          version 0 } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 8 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "PROVISIONAL" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 2478422 } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      comment {
        {
          type genomic ,
          heading "Reference" ,
          accession "NG_001067" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 20270626 } ,
              anchor "NG_001067" } } ,
          seqs {
            int {
              from 1 ,
              to 3003 ,
              strand plus ,
              id
                gi 20270626 } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "M24415" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 187575 } ,
              anchor "M24415" } } ,
          seqs {
            int {
              from 177 ,
              to 2881 ,
              strand plus ,
              id
                gi 187575 } } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "3" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_009714.16&gene=A2MP&lid=3&from=2143176&to=2145882" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "3" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96
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        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "AceView" ,
                tag
                  id 3 } ,
              anchor "AceView" ,
              url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l
ocusid&org=9606&l=3" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:128103" } } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 3 } } ,
  xtra-index-terms {
    "LOC3" } }
Entrezgene ::= {
  track-info {
    geneid 4 ,
    status discontinued ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 9 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "1" } } } ,
  gene {
    desc "adenovirus-12 chromosome modification site 1C" ,
    maploc "1q42-q43" ,
    syn {
      "A12M1" } } ,
  prot {
    name {
      "adenovirus-12 chromosome modification site 1C" ,
      "Adenovirus-12 chromosome modification site-1q1" } } ,
  location {
    {
      display-str "1q42-q43" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 4 ,
    src-str2 "4" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  comments {
    {
      type comment ,
      heading "RefSeq Status" ,
      label "WITHDRAWN" ,
      version 0 } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:118950" } } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 4 } } ,
  xtra-index-terms {
    "LOC4" } }
Entrezgene ::= {
  track-info {
    geneid 5 ,
    status discontinued ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 9 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "1" } } } ,
  gene {
    desc "adenovirus-12 chromosome modification site 1A" ,
    maploc "1p36" ,
    syn {
      "A12M2" } } ,
  prot {
    name {
      "adenovirus-12 chromosome modification site 1A" ,
      "Adenovirus-12 chromosome modification site-1p" } } ,
  location {
    {
      display-str "1p36" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 5 ,
    src-str2 "5" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  comments {
    {
      type comment ,
      heading "RefSeq Status" ,
      label "WITHDRAWN" ,
      version 0 } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:118951" } } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 5 } } ,
  xtra-index-terms {
    "LOC5" } }
Entrezgene ::= {
  track-info {
    geneid 6 ,
    status discontinued ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 9 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "1" } } } ,
  gene {
    desc "adenovirus-12 chromosome modification site 1B" ,
    maploc "1q21" ,
    syn {
      "A12M3" } } ,
  prot {
    name {
      "adenovirus-12 chromosome modification site 1B" ,
      "Adenovirus-12 chromosome modification site-1q2" } } ,
  location {
    {
      display-str "1q21" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 6 ,
    src-str2 "6" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  comments {
    {
      type comment ,
      heading "RefSeq Status" ,
      label "WITHDRAWN" ,
      version 0 } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:118952" } } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 6 } } ,
  xtra-index-terms {
    "LOC6" } }
Entrezgene ::= {
  track-info {
    geneid 7 ,
    status discontinued ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 9 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "17" } } } ,
  gene {
    desc "adenovirus-12 chromosome modification site 17" ,
    maploc "17q21-q22" ,
    syn {
      "A12M4" } } ,
  prot {
    name {
      "adenovirus-12 chromosome modification site 17" } } ,
  location {
    {
      display-str "17q21-q22" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 7 ,
    src-str2 "7" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  comments {
    {
      type comment ,
      heading "RefSeq Status" ,
      label "WITHDRAWN" ,
      version 0 } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:118953" } } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 7 } } ,
  xtra-index-terms {
    "LOC7" } }
Entrezgene ::= {
  track-info {
    geneid 8 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 3 ,
        day 16 ,
        hour 16 ,
        minute 24 ,
        second 0 } } ,
  type unknown ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "11" } } } ,
  gene {
    locus "AA" ,
    desc "atrophia areata, peripapillary chorioretinal degeneration" ,
    maploc "11p15" ,
    db {
      {
        db "MIM" ,
        tag
          id 108985 } } ,
    locus-tag "HGNC:11" } ,
  location {
    {
      display-str "11p15" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 8 ,
    src-str2 "8" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "AA" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "atrophia areata, peripapillary chorioretinal degeneration" ,
          version 0 } } } ,
    {
      type property ,
      label "Property" ,
      text "phenotype only" ,
      version 0 } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 11 } } } } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 7795606 } } ,
    {
      type comment ,
      heading "Phenotypes" ,
      version 0 ,
      comment {
        {
          type phenotype ,
          text "Atrophia areata" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  id 108985 } ,
              anchor "MIM: 108985" } } } ,
        {
          type phenotype ,
          label "AA" ,
          text "atrophia areata, peripapillary chorioretinal degeneration" ,
          version 0 ,
          source {
            {
              src {
                db "HGNC" ,
                tag
                  id 11 } ,
              anchor "HGNC:11" } } } } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 31863 } ,
              anchor "D11S902" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "072YD3" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "AFM072yd3" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "GDB:187919" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "HS072YD3" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH15041" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH3044" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH51860" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 31863 } ,
              anchor "D11S902 (flanking)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "072YD3" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "AFM072yd3" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "GDB:187919" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "HS072YD3" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH15041" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH3044" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH51860" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 67612 } ,
              anchor "D11S1323" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "AFM248xf9" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH31202" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH73986" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "SHGC-2070" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 67612 } ,
              anchor "D11S1323 (flanking)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "AFM248xf9" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH31202" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH73986" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "SHGC-2070" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          text "MIM" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  str "108985" } ,
              anchor "108985" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:568984" } } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 8 } ,
    {
      db "MIM" ,
      tag
        id 108985 } } ,
  xtra-index-terms {
    "LOC8" } ,
  xtra-properties {
    {
      tag "PROP" ,
      value "phenotype" } ,
    {
      tag "PROP" ,
      value "phenotype only" } } }
Entrezgene ::= {
  track-info {
    geneid 9 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 15 ,
        hour 9 ,
        minute 40 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "8" } } } ,
  gene {
    locus "NAT1" ,
    desc "N-acetyltransferase 1 (arylamine N-acetyltransferase)" ,
    maploc "8p23.1-p21.3" ,
    db {
      {
        db "MIM" ,
        tag
          id 108345 } } ,
    syn {
      "AAC1" } ,
    locus-tag "HGNC:7645" } ,
  prot {
    name {
      "N-acetyltransferase 1" ,
      "arylamine N-acetyltransferase 1" ,
      "arylamide acetylase 1 (N-acetyltransferase 1)" } } ,
  location {
    {
      display-str "8p23.1-p21.3" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 9 ,
    src-str2 "9" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000008" ,
      version 9 ,
      seqs {
        int {
          from 18111894 ,
          to 18125099 ,
          strand plus ,
          id
            gi 51511724 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000662" ,
          version 4 ,
          genomic-coords {
            mix {
              int {
                from 18111894 ,
                to 18111968 ,
                strand plus ,
                id
                  gi 51511724 } ,
              int {
                from 18121199 ,
                to 18121277 ,
                strand plus ,
                id
                  gi 51511724 } ,
              int {
                from 18123830 ,
                to 18125099 ,
                strand plus ,
                id
                  gi 51511724 } } } ,
          seqs {
            whole
              gi 42741670 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_000653" ,
              version 3 ,
              genomic-coords {
                int {
                  from 18123836 ,
                  to 18124708 ,
                  strand plus ,
                  id
                    gi 51511724 } } ,
              seqs {
                whole
                  gi 42741671 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.5" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.5" } } } } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_030737" ,
      version 9 ,
      seqs {
        int {
          from 5912542 ,
          to 5925747 ,
          strand plus ,
          id
            gi 51466871 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000662" ,
          version 4 ,
          genomic-coords {
            mix {
              int {
                from 5912542 ,
                to 5912616 ,
                strand plus ,
                id
                  gi 51466871 } ,
              int {
                from 5921847 ,
                to 5921925 ,
                strand plus ,
                id
                  gi 51466871 } ,
              int {
                from 5924478 ,
                to 5925747 ,
                strand plus ,
                id
                  gi 51466871 } } } ,
          seqs {
            whole
              gi 42741670 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_000653" ,
              version 3 ,
              genomic-coords {
                int {
                  from 5924484 ,
                  to 5925356 ,
                  strand plus ,
                  id
                    gi 51466871 } } ,
              seqs {
                whole
                  gi 42741671 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.5" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.5" } } } } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086740" ,
      version 1 ,
      seqs {
        int {
          from 5593338 ,
          to 5606579 ,
          strand plus ,
          id
            gi 51467159 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000662" ,
          version 4 ,
          genomic-coords {
            mix {
              int {
                from 5593338 ,
                to 5593412 ,
                strand plus ,
                id
                  gi 51467159 } ,
              int {
                from 5602680 ,
                to 5602758 ,
                strand plus ,
                id
                  gi 51467159 } ,
              int {
                from 5605310 ,
                to 5606579 ,
                strand plus ,
                id
                  gi 51467159 } } } ,
          seqs {
            whole
              gi 42741670 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_000653" ,
              version 3 ,
              genomic-coords {
                int {
                  from 5605316 ,
                  to 5606188 ,
                  strand plus ,
                  id
                    gi 51467159 } } ,
              seqs {
                whole
                  gi 42741671 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.5" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.5" } } } } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "NAT1" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "N-acetyltransferase 1 (arylamine N-acetyltransferase)" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "GOA" ,
          url "http://www.ebi.ac.uk/GOA/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16407 } ,
                  anchor "acetyltransferase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 10908296 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4060 } ,
                  anchor "arylamine N-acetyltransferase activity" ,
                  post-text "evidence: TAS" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16740 } ,
                  anchor "transferase activity" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8152 } ,
                  anchor "metabolism" ,
                  post-text "evidence: IEA" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 37329 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=8&M
APS=genes-r-org/rat-chr/human%3A8,genes-r-org/mouse-chr/human%3A8,genes-r-org/
human-chr8&query=e%3A9[id]+AND+gene[obj_type]&QSTR=nat1&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 7645 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "VALIDATED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 15487985 ,
        pmid 15320760 ,
        pmid 15226672 ,
        pmid 15039438 ,
        pmid 14705222 ,
        pmid 14672957 ,
        pmid 14608357 ,
        pmid 14517345 ,
        pmid 12946272 ,
        pmid 12902152 ,
        pmid 12888564 ,
        pmid 12860276 ,
        pmid 12832400 ,
        pmid 12692115 ,
        pmid 12682333 ,
        pmid 12485520 ,
        pmid 12477932 ,
        pmid 12355549 ,
        pmid 12052143 ,
        pmid 12037388 ,
        pmid 11955677 ,
        pmid 11955676 ,
        pmid 11927838 ,
        pmid 11470991 ,
        pmid 10908296 ,
        pmid 10862520 ,
        pmid 10767335 ,
        pmid 9168895 ,
        pmid 8110178 ,
        pmid 7773298 ,
        pmid 2340091 ,
        pmid 1968463 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 24445 } ,
              anchor "STS-R79401" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "RH40594" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "sts-R79401" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 57372 } ,
              anchor "STS-D90041" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
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            {
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    {
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        {
          type comment ,
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                  str "108345" } ,
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          type comment ,
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                  str "9" } ,
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              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
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          type comment ,
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              src {
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        {
          type comment ,
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                  str "" } ,
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        {
          type comment ,
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              src {
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                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
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        {
          type comment ,
          text "PharmGKB" ,
          version 0 ,
          source {
            {
              src {
                db "PharmGKB" ,
                tag
                  str "PA17" } ,
              anchor "PA17" } } } ,
        {
          type comment ,
          text "Arylamine N-Acetyltransferase Nomenclature" ,
          version 0 ,
          source {
            {
              src {
                db "Arylamine N-Acetyltransferase Nomenclature" ,
                tag
                  str "Arylamine N-Acetyltransferase Nomenclature" } ,
              anchor "Arylamine N-Acetyltransferase Nomenclature" ,
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        {
          type comment ,
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          source {
            {
              src {
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                tag
                  str "BC047666" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC047666" } } } } } ,
    {
      type generif ,
      text "In breast, NAT1 mRNA is transcribed from a strong promoter located
 11.8 kb upstream of the translated exon, and the mature spliced mRNA includes
 at least one additional non-coding exon." ,
      version 0 ,
      refs {
        pmid 15226672 } ,
      create-date
        str "Mar 26 2005 10:01AM" ,
      update-date
        str "Mar 26 2005  1:53PM" } ,
    {
      type generif ,
      text "Polymorphism at the NAT1 locus has been associated with the
 existence of at least 26 allelic variants, generating phenotypic variations
 in terms NAT-1 catalytic activity. This genetic variation affects the
 acetylator status of individuals." ,
      version 0 ,
      refs {
        pmid 15320760 } ,
      create-date
        str "Dec 18 2004 10:01AM" ,
      update-date
        str "Mar 17 2005  6:52AM" } ,
    {
      type generif ,
      text "NAT1 exists in the cell in either a stable acetylated state or an
 unstable non-acetylated state and mutations in the NAT1 gene that prevent
 protein acetylation produce a slow acetylator phenotype" ,
      version 0 ,
      refs {
        pmid 15039438 } ,
      create-date
        str "Jul  6 2004 11:50AM" ,
      update-date
        str "Jul  6 2004 12:11PM" } ,
    {
      type generif ,
      text "Analysis of the effect of active NAT-1 overexpression in a normal
 luminal epithelial-derived cell line demonstrated enhanced growth properties
 and etoposide resistance relative to control cells." ,
      version 0 ,
      refs {
        pmid 14517345 } ,
      create-date
        str "Jun 23 2004  4:43PM" ,
      update-date
        str "Jun 23 2004  5:16PM" } ,
    {
      type generif ,
      text "cellular generation of peroxynitrite may contribute to
 carcinogenesis and tumor progression by weakening key cellular defense
 enzymes such as arylamine N-acetyltransferase 1 (NAT1)" ,
      version 0 ,
      refs {
        pmid 14672957 } ,
      create-date
        str "Mar 24 2004 12:00AM" ,
      update-date
        str "May  9 2004  7:01AM" } ,
    {
      type generif ,
      text "although there is little overall association between NAT genotypes
 and risk of developing systemic lupus erythematosus, the interaction between
 NAT1 and NAT2 and specific exposures such as hair dyes may be important." ,
      version 0 ,
      refs {
        pmid 14705222 } ,
      create-date
        str "Apr 16 2004 12:00AM" ,
      update-date
        str "May  2 2004  7:01AM" } ,
    {
      type generif ,
      text "A putative RUNX1 binding site variant of NAT9 is associated with
 susceptibility to psoriasis" ,
      version 0 ,
      refs {
        pmid 14608357 } ,
      create-date
        str "Dec 18 2003 12:00AM" ,
      update-date
        str "Jan 11 2004  7:03AM" } ,
    {
      type generif ,
      text "Identification of minimal promoter sequences for transcription
 factor binding sites in the human N-acetyltransferase Type I gene. that binds" ,
      version 0 ,
      refs {
        pmid 12946272 } ,
      create-date
        str "Nov 24 2003 12:00AM" ,
      update-date
        str "Dec  7 2003  7:02AM" } ,
    {
      type generif ,
      text "Oxidative stress and cellular redox status may regulate NAT1
 activity and have important consequences with regard to drug
 biotransformation and cancer risk." ,
      version 0 ,
      refs {
        pmid 12832400 } ,
      create-date
        str "Oct  7 2003 12:00AM" ,
      update-date
        str "Nov 16 2003  7:02AM" } ,
    {
      type generif ,
      text "Variation in capacity for acetylation of 4ABP and PABA resulting
 from human NAT1 transgene is insufficient to affect 4ABP genotoxicity in
 mouse liver." ,
      version 0 ,
      refs {
        pmid 12902152 } ,
      create-date
        str "Sep  6 2003 12:00AM" ,
      update-date
        str "Sep 14 2003  7:01AM" } ,
    {
      type generif ,
      text "It is unlikely that the NAT1*10 or NAT2 rapid/intermediate
 genotypes are related to stomach cancer risk." ,
      version 0 ,
      refs {
        pmid 12692115 } ,
      create-date
        str "Sep  4 2003 12:00AM" ,
      update-date
        str "Sep 28 2003  7:01AM" } ,
    {
      type generif ,
      text "genetic polymorphisms of NAT1 and NAT2 have no independent effect
 on breast cancer risk, but they modulate breast cancer risk in the presence
 of GSTM1 and GSTT1 null genotypes." ,
      version 0 ,
      refs {
        pmid 12860276 } ,
      create-date
        str "Aug 18 2003 12:00AM" ,
      update-date
        str "Aug 24 2003  7:01AM" } ,
    {
      type generif ,
      text "NAT1 * 10 has increased risk of sporadic colorectal adenocarcinoma
 and significantly related to the later stage tumors, is not significantly
 related to the tumor location" ,
      version 0 ,
      refs {
        pmid 12485520 } ,
      create-date
        str "Jun 25 2003 12:00AM" ,
      update-date
        str "Jul 13 2003  7:01AM" } ,
    {
      type generif ,
      text "Single nucleotide polymorphisms of NAT1 and NAT2, and acetylation
 haplotype were not associated with increased risk for Parkinson disease" ,
      version 0 ,
      refs {
        pmid 12682333 } ,
      create-date
        str "Apr 11 2003 12:00AM" ,
      update-date
        str "Apr 27 2003  7:01AM" } ,
    {
      type generif ,
      text "NAT1 polymorphism (NAT1*10) indicates increased susceptibility to
 prostate cancer" ,
      version 0 ,
      refs {
        pmid 12355549 } ,
      create-date
        str "Oct 31 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:01AM" } ,
    {
      type generif ,
      text "susceptibility gene for multifactorial adverse effects and
 xenobiotic-related diseases (review)" ,
      version 0 ,
      refs {
        pmid 12052143 } ,
      create-date
        str "Sep 12 2002 12:00AM" ,
      update-date
        str "Sep 16 2002  5:48AM" } ,
    {
      type generif ,
      text "NAT1 genotype acts as a modifier of diisothionate
 exposure-associated asthma risk" ,
      version 0 ,
      refs {
        pmid 11927838 } ,
      create-date
        str "Aug 30 2002 12:00AM" ,
      update-date
        str "Sep 16 2002  5:48AM" } ,
    {
      type generif ,
      text "NAT1 polymorphisms may be correlated with an increased risk of
 larynx cancer" ,
      version 0 ,
      refs {
        pmid 12037388 } ,
      create-date
        str "Aug 19 2002 12:00AM" ,
      update-date
        str "Aug 28 2002  6:15PM" } ,
    {
      type generif ,
      text "paclitaxel affected human leukemia HL-60 cells arylamine
 N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adduct formation." ,
      version 0 ,
      refs {
        pmid 11955677 } ,
      create-date
        str "Jun 19 2002 12:00AM" ,
      update-date
        str "Jun 24 2002  6:31AM" } ,
    {
      type generif ,
      text "paclitaxel is an uncompetitive inhibitor to arylamine
 N-acetyltransferase (NAT) enzyme" ,
      version 0 ,
      refs {
        pmid 11955676 } ,
      create-date
        str "Jun 19 2002 12:00AM" ,
      update-date
        str "Jun 24 2002  6:31AM" } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 9 } ,
    {
      db "MIM" ,
      tag
        id 108345 } } ,
  xtra-index-terms {
    "LOC9" } }
Entrezgene ::= {
  track-info {
    geneid 10 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 17 ,
        hour 11 ,
        minute 9 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "8" } } } ,
  gene {
    locus "NAT2" ,
    desc "N-acetyltransferase 2 (arylamine N-acetyltransferase)" ,
    maploc "8p22" ,
    db {
      {
        db "MIM" ,
        tag
          id 243400 } } ,
    syn {
      "AAC2" } ,
    locus-tag "HGNC:7646" } ,
  prot {
    name {
      "arylamide acetylase 2" ,
      "Arylamine N-acetyltransferase-2" ,
      "arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation)" } } ,
  summary "The intronless NAT2 gene encodes N-acetyltransferase 2 (arylamine
 N-acetyltransferase 2). This enzyme functions to both activate and deactivate
 arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are
 reponsible for the N-acetylation polymorphism in which human populations
 segregate into rapid,intermediate, and slow acetylator phenotypes.
 Polymorphisms in NAT2 are also associated with higher incidences of cancer
 and drug toxicity.A second arylamine N-acetyltransferase gene (NAT1) is
 located near NAT2." ,
  location {
    {
      display-str "8p22" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 10 ,
    src-str2 "10" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000008" ,
      version 9 ,
      seqs {
        int {
          from 18293034 ,
          to 18302961 ,
          strand plus ,
          id
            gi 51511724 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000015" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 18293034 ,
                to 18293134 ,
                strand plus ,
                id
                  gi 51511724 } ,
              int {
                from 18301787 ,
                to 18302961 ,
                strand plus ,
                id
                  gi 51511724 } } } ,
          seqs {
            whole
              gi 4557782 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_000006" ,
              version 1 ,
              genomic-coords {
                int {
                  from 18301793 ,
                  to 18302665 ,
                  strand plus ,
                  id
                    gi 51511724 } } ,
              seqs {
                whole
                  gi 4557783 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.5" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.5" } } } } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_030737" ,
      version 9 ,
      seqs {
        int {
          from 6093682 ,
          to 6103609 ,
          strand plus ,
          id
            gi 51466871 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000015" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 6093682 ,
                to 6093782 ,
                strand plus ,
                id
                  gi 51466871 } ,
              int {
                from 6102435 ,
                to 6103609 ,
                strand plus ,
                id
                  gi 51466871 } } } ,
          seqs {
            whole
              gi 4557782 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_000006" ,
              version 1 ,
              genomic-coords {
                int {
                  from 6102441 ,
                  to 6103313 ,
                  strand plus ,
                  id
                    gi 51466871 } } ,
              seqs {
                whole
                  gi 4557783 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.5" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.5" } } } } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086740" ,
      version 1 ,
      seqs {
        int {
          from 5773920 ,
          to 5783845 ,
          strand plus ,
          id
            gi 51467159 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_000015" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 5773920 ,
                to 5774020 ,
                strand plus ,
                id
                  gi 51467159 } ,
              int {
                from 5782671 ,
                to 5783845 ,
                strand plus ,
                id
                  gi 51467159 } } } ,
          seqs {
            whole
              gi 4557782 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_000006" ,
              version 1 ,
              genomic-coords {
                int {
                  from 5782677 ,
                  to 5783549 ,
                  strand plus ,
                  id
                    gi 51467159 } } ,
              seqs {
                whole
                  gi 4557783 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.5" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.5" } } } } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "NAT2" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "N-acetyltransferase 2 (arylamine N-acetyltransferase)" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "GOA" ,
          url "http://www.ebi.ac.uk/GOA/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16407 } ,
                  anchor "acetyltransferase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 2340091 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4060 } ,
                  anchor "arylamine N-acetyltransferase activity" ,
                  post-text "evidence: TAS" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16740 } ,
                  anchor "transferase activity" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8152 } ,
                  anchor "metabolism" ,
                  post-text "evidence: IEA" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 32047 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=8&M
APS=genes-r-org/rat-chr/human%3A8,genes-r-org/mouse-chr/human%3A8,genes-r-org/
human-chr8&query=e%3A10[id]+AND+gene[obj_type]&QSTR=nat2&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 7646 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 15671210 ,
        pmid 15637738 ,
        pmid 15609332 ,
        pmid 15588473 ,
        pmid 15225898 ,
        pmid 15162844 ,
        pmid 15005011 ,
        pmid 14747882 ,
        pmid 14705222 ,
        pmid 14648207 ,
        pmid 14618622 ,
        pmid 14528063 ,
        pmid 12884528 ,
        pmid 12877350 ,
        pmid 12860276 ,
        pmid 12835615 ,
        pmid 12773763 ,
        pmid 12760253 ,
        pmid 12724621 ,
        pmid 12692115 ,
        pmid 12682333 ,
        pmid 12654968 ,
        pmid 12622714 ,
        pmid 12611196 ,
        pmid 12477932 ,
        pmid 12474054 ,
        pmid 12469231 ,
        pmid 12465141 ,
        pmid 12430181 ,
        pmid 12397635 ,
        pmid 12360107 ,
        pmid 12355549 ,
        pmid 12235453 ,
        pmid 12222688 ,
        pmid 12163321 ,
        pmid 12037388 ,
        pmid 12016157 ,
        pmid 12015038 ,
        pmid 11915035 ,
        pmid 11872636 ,
        pmid 11846845 ,
        pmid 11470991 ,
        pmid 9202751 ,
        pmid 8460648 ,
        pmid 8110178 ,
        pmid 8102597 ,
        pmid 7915226 ,
        pmid 7902079 ,
        pmid 7773298 ,
        pmid 2734109 ,
        pmid 2340091 ,
        pmid 2068113 ,
        pmid 1996083 ,
        pmid 1968463 ,
        pmid 1676262 ,
        pmid 1441598 ,
        pmid 1381364 ,
        pmid 1306121 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 17088 } ,
              anchor "G06461" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "WI-7224" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 44576 } ,
              anchor "WIAF-2120" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "RH11442" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH20" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "WIAF-2120-STS" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "gdb:4559542" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "stSG40" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 137181 } ,
              anchor "G59899" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "SHGC-130680" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 155563 } ,
              anchor "GDB:187676" ,
              post-text "(e-PCR)" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 156422 } ,
              anchor "GDB:310612" ,
              post-text "(e-PCR)" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 156423 } ,
              anchor "GDB:310613" ,
              post-text "(e-PCR)" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 157141 } ,
              anchor "GDB:386004" ,
              post-text "(e-PCR)" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 272646 } ,
              anchor "PMC310725P3" ,
              post-text "(e-PCR)" } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_000015" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 4557782 } ,
              anchor "NM_000015" } } ,
          seqs {
            whole
              gi 4557782 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_000006" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 4557783 } ,
                  anchor "NP_000006" ,
                  post-text "arylamide acetylase 2" } } ,
              seqs {
                whole
                  gi 4557783 } ,
              comment {
                {
                  type other ,
                  heading "Consensus CDS (CCDS)" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "CCDS" ,
                        tag
                          str "CCDS6008.1" } ,
                      anchor "CCDS6008.1" } } } ,
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 4557783 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 1353 } ,
                          anchor "pfam00797: Acetyltransf_2;
 N-acetyltransferase" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 20 - 280  Blast Score: 1005" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "D90042" } ,
                  anchor "D90042" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF042740" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 2801806 } ,
              anchor "AF042740" } } ,
          seqs {
            whole
              gi 2801806 } ,
          products {
            {
              type peptide ,
              accession "AAC03773" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 2801807 } ,
                  anchor "AAC03773" } } ,
              seqs {
                whole
                  gi 2801807 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF055874" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 3063613 } ,
              anchor "AF055874" } } ,
          seqs {
            whole
              gi 3063613 } ,
          products {
            {
              type peptide ,
              accession "AAC14117" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 3063614 } ,
                  anchor "AAC14117" } } ,
              seqs {
                whole
                  gi 3063614 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF055875" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 3063615 } ,
              anchor "AF055875" } } ,
          seqs {
            whole
              gi 3063615 } ,
          products {
            {
              type peptide ,
              accession "AAC14118" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 3063616 } ,
                  anchor "AAC14118" } } ,
              seqs {
                whole
                  gi 3063616 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF320309" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 11321494 } ,
              anchor "AF320309" } } ,
          seqs {
            whole
              gi 11321494 } ,
          products {
            {
              type peptide ,
              accession "AAG34181" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 11321495 } ,
                  anchor "AAG34181" } } ,
              seqs {
                whole
                  gi 11321495 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF348074" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 14009675 } ,
              anchor "AF348074" } } ,
          seqs {
            whole
              gi 14009675 } ,
          products {
            {
              type peptide ,
              accession "AAK51710" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 14009676 } ,
                  anchor "AAK51710" } } ,
              seqs {
                whole
                  gi 14009676 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AF348075" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 14009677 } ,
              anchor "AF348075" } } ,
          seqs {
            whole
              gi 14009677 } ,
          products {
            {
              type peptide ,
              accession "AAK51711" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 14009678 } ,
                  anchor "AAK51711" } } ,
              seqs {
                whole
                  gi 14009678 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AY230251" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 29423785 } ,
              anchor "AY230251" } } ,
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            whole
              gi 29423785 } ,
          products {
            {
              type peptide ,
              accession "AAO73561" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 29423786 } ,
                  anchor "AAO73561" } } ,
              seqs {
                whole
                  gi 29423786 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AY230252" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 29423789 } ,
              anchor "AY230252" } } ,
          seqs {
            whole
              gi 29423789 } ,
          products {
            {
              type peptide ,
              accession "AAO73562" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 29423790 } ,
                  anchor "AAO73562" } } ,
              seqs {
                whole
                  gi 29423790 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "AY331807" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 32402490 } ,
              anchor "AY331807" } } ,
          seqs {
            whole
              gi 32402490 } ,
          products {
            {
              type peptide ,
              accession "AAP81164" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 32402491 } ,
                  anchor "AAP81164" } } ,
              seqs {
                whole
                  gi 32402491 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "D10870" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 219871 } ,
              anchor "D10870" } } ,
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              gi 219871 } ,
          products {
            {
              type peptide ,
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              version 1 ,
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                {
                  src {
                    db "Protein" ,
                    tag
                      id 219872 } ,
                  anchor "BAA01640" } } ,
              seqs {
                whole
                  gi 219872 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "D10871" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 219874 } ,
              anchor "D10871" } } ,
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              gi 219874 } ,
          products {
            {
              type peptide ,
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                {
                  src {
                    db "Protein" ,
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                      id 219875 } ,
                  anchor "BAA01641" } } ,
              seqs {
                whole
                  gi 219875 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "D10872" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 219877 } ,
              anchor "D10872" } } ,
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            whole
              gi 219877 } ,
          products {
            {
              type peptide ,
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              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
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        {
          type comment ,
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          version 0 ,
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            {
              src {
                db "PharmGKB" ,
                tag
                  str "PA18" } ,
              anchor "PA18" } } } ,
        {
          type comment ,
          text "Arylamine N-Acetyltransferase Nomenclature" ,
          version 0 ,
          source {
            {
              src {
                db "Arylamine N-Acetyltransferase Nomenclature" ,
                tag
                  str "Arylamine N-Acetyltransferase Nomenclature" } ,
              anchor "Arylamine N-Acetyltransferase Nomenclature" ,
              url "http://www.louisville.edu/medschool/pharmacology/NAT.html" } } } ,
        {
          type comment ,
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              src {
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    {
      type generif ,
      text "there is no association between endometriosis and NAT2 in South
 Indian women" ,
      version 0 ,
      refs {
        pmid 15588473 } ,
      create-date
        str "Mar 19 2005 10:01AM" ,
      update-date
        str "Mar 19 2005 11:47AM" } ,
    {
      type generif ,
      text "Risks for colorectal cancer are significantly associated with the
 genetic polymorphisms of GSTT1 deletion, NAT2-rapid acetylator phenotype and
 genotye and NAT2-rapid acetylator phenotype." ,
      version 0 ,
      refs {
        pmid 15637738 } ,
      create-date
        str "Mar  7 2005  7:07PM" ,
      update-date
        str "Mar  8 2005 12:10AM" } ,
    {
      type generif ,
      text "Cigarette smoking is associated with increased risk of breast
 cancer in women with the NAT2 slow acetylator genotype." ,
      version 0 ,
      refs {
        pmid 15225898 } ,
      create-date
        str "Nov 13 2004 10:01AM" ,
      update-date
        str "Nov 13 2004 10:50AM" } ,
    {
      type generif ,
      text "N-acetyltransferase 2 polymorphism does not play an important role
 in breast cancer risk of Turkish women by altering the capacity in
 deactivation of environmental carcinogens" ,
      version 0 ,
      refs {
        pmid 15162844 } ,
      create-date
        str "Oct  4 2004 10:33AM" ,
      update-date
        str "Oct  4 2004 11:19AM" } ,
    {
      type generif ,
      text "NAT2 slow acetylator genotypes might modulate the effect of
 carcinogenic arylamines contained in tobacco smoke." ,
      version 0 ,
      refs {
        pmid 14648207 } ,
      create-date
        str "Sep 27 2004  4:34PM" ,
      update-date
        str "Sep 27 2004  5:11PM" } ,
    {
      type generif ,
      text "Arylamine N-acetyltransferase 2 is a genetically polymorphic phase
 II enzyme with a role in the metabolism of many xenobiotics." ,
      version 0 ,
      refs {
        pmid 14747882 } ,
      create-date
        str "Aug  2 2004  1:09PM" ,
      update-date
        str "Aug  2 2004  1:38PM" } ,
    {
      type generif ,
      text "although there is little overall association between NAT genotypes
 and risk of developing systemic lupus erythematosus, the interaction between
 NAT1 and NAT2 and specific exposures such as hair dyes may be important" ,
      version 0 ,
      refs {
        pmid 14705222 } ,
      create-date
        str "Apr 16 2004 12:00AM" ,
      update-date
        str "May  2 2004  7:01AM" } ,
    {
      type generif ,
      text "The NAT2 acetylator genotype may modify esophageal cancer risk in
 humans from exposure to barbecued/grilled meat." ,
      version 0 ,
      refs {
        pmid 12773763 } ,
      create-date
        str "Feb 13 2004 12:00AM" ,
      update-date
        str "Feb 22 2004  7:01AM" } ,
    {
      type generif ,
      text "N-acetyltransferase 2 polymorphism does not differ between
 patients suffering from atopic dermatitis and healthy subjects" ,
      version 0 ,
      refs {
        pmid 14528063 } ,
      create-date
        str "Feb  5 2004 12:00AM" ,
      update-date
        str "Feb 15 2004  6:33PM" } ,
    {
      type generif ,
      text "Genetic NAT2 polymorphism may play a role in lifestyle
 factors-related hepato- carcinogenesis, particulary critical in smoking
 related hepatocarcinogenesis." ,
      version 0 ,
      refs {
        pmid 12877350 } ,
      create-date
        str "Feb  4 2004 12:00AM" ,
      update-date
        str "Feb 15 2004  6:32PM" } ,
    {
      type generif ,
      text "Slow acetylation activity is associated with age-related cataract
 formation." ,
      version 0 ,
      refs {
        pmid 12724621 } ,
      create-date
        str "Jan  6 2004 12:00AM" ,
      update-date
        str "Feb 22 2004  7:01AM" } ,
    {
      type generif ,
      text "A significant association between Parkinson disease & the slow
 acetylator genotype for N-acetyltransferase 2 in Hong Kong Chinesed provides
 evidence for a possible functional relationship between NAT2 slow acetylator
 genotype & PD in both racial groups." ,
      version 0 ,
      refs {
        pmid 12654968 } ,
      create-date
        str "Dec 23 2003 12:00AM" ,
      update-date
        str "Jan 18 2004  7:01AM" } ,
    {
      type generif ,
      text "RFLP of the gene coding for N-acetyltransferase 2 (NAT2) was typed
 in populations of the Volga-Ural region (Bashkirs, Tatars, Chuvashes,
 Udmurts, and Russians) and in patients with chronic obstructive pulmonary
 disease (COPD) and in healthy individuals" ,
      version 0 ,
      refs {
        pmid 12884528 } ,
      create-date
        str "Dec 18 2003 12:00AM" ,
      update-date
        str "Jan 25 2004  7:01AM" } ,
    {
      type generif ,
      text "We conclude that smoking increases risk of colorectal adenomas and
 that SULT1A1 and NAT2 only modestly modify this association." ,
      version 0 ,
      refs {
        pmid 14618622 } ,
      create-date
        str "Dec 11 2003 12:00AM" ,
      update-date
        str "Dec 21 2003  7:01AM" } ,
    {
      type generif ,
      text "In human, NAT2 polymorphism may be a genetic risk factor for joint
 destruction." ,
      version 0 ,
      refs {
        pmid 15005011 } ,
      create-date
        str "May  7 2004 12:00AM" ,
      update-date
        str "May 16 2004  7:01AM" } ,
    {
      type generif ,
      text "It is unlikely that the NAT1*10 or NAT2 rapid/intermediate
 genotypes are related to stomach cancer risk." ,
      version 0 ,
      refs {
        pmid 12692115 } ,
      create-date
        str "Sep  4 2003 12:00AM" ,
      update-date
        str "Sep 28 2003  7:01AM" } ,
    {
      type generif ,
      text "genetic polymorphisms of NAT1 and NAT2 have no independent effect
 on breast cancer risk, but they modulate breast cancer risk in the presence
 of GSTM1 and GSTT1 null genotypes." ,
      version 0 ,
      refs {
        pmid 12860276 } ,
      create-date
        str "Aug 18 2003 12:00AM" ,
      update-date
        str "Aug 24 2003  7:01AM" } ,
    {
      type generif ,
      text "NAT2 slow acetylator genotype plays an important role in
 determining the risk of developing prostate cancer in Japanese men and is
 also associated with more clinically advanced and pathologically aggressive
 disease." ,
      version 0 ,
      refs {
        pmid 12622714 } ,
      create-date
        str "Aug  9 2003 12:00AM" ,
      update-date
        str "Aug 24 2003  7:01AM" } ,
    {
      type generif ,
      text "Polymorphism of Nat2 encoding phase 2 xenobiotic detoxication
 enzyme was studied." ,
      version 0 ,
      refs {
        pmid 12760253 } ,
      create-date
        str "Jun 26 2003 12:00AM" ,
      update-date
        str "Aug 10 2003  7:01AM" } ,
    {
      type generif ,
      text "This enzyme is polymorphic in various ethnic populations of South
 India." ,
      version 0 ,
      refs {
        pmid 12469231 } ,
      create-date
        str "May 24 2003 12:00AM" ,
      update-date
        str "Jul 27 2003  7:01AM" } ,
    {
      type generif ,
      text "Maternal NAT2 acetylator status seems not to be an important
 factor in the etiology of orofacial clefts." ,
      version 0 ,
      refs {
        pmid 12397635 } ,
      create-date
        str "May  7 2003 12:00AM" ,
      update-date
        str "Jun  1 2003  7:01AM" } ,
    {
      type generif ,
      text "Genotyping the NAT2 gene and estimating diplotype configuration
 before administration of SSZ may reduce the frequency of adverse effects in
 Japanese patients with RA." ,
      version 0 ,
      refs {
        pmid 12465141 } ,
      create-date
        str "May  2 2003 12:00AM" ,
      update-date
        str "May 11 2003  7:01AM" } ,
    {
      type generif ,
      text "Single nucleotide polymorphisms of NAT1 and NAT2, and acetylation
 haplotype were not associated with increased risk for Parkinson disease" ,
      version 0 ,
      refs {
        pmid 12682333 } ,
      create-date
        str "Apr 11 2003 12:00AM" ,
      update-date
        str "Apr 27 2003  7:01AM" } ,
    {
      type generif ,
      text "lack of association between polymorphism of this gene and systemic
 lupus erythematosus" ,
      version 0 ,
      refs {
        pmid 12360107 } ,
      create-date
        str "Apr  9 2003 12:00AM" ,
      update-date
        str "Apr 27 2003  7:01AM" } ,
    {
      type generif ,
      text "Polymorphic N-acetyltransferase (NAT2) is involved in the
 metabolism of several compounds relevant in pharmacology or toxicology, with
 diverse clinical consequences--review" ,
      version 0 ,
      refs {
        pmid 12611196 } ,
      create-date
        str "Mar 24 2003 12:00AM" ,
      update-date
        str "Mar 31 2003  6:30AM" } ,
    {
      type generif ,
      text "N-acetyltransferase 2*19 possessing the C190T (R64W) single
 nucleotide polymorphisms encodes a slow acetylator phenotype for both N- and
 O-acetylation, due to a reduction in the amount and stability of the NAT2 19
 allozyme" ,
      version 0 ,
      refs {
        pmid 12222688 } ,
      create-date
        str "Mar 10 2003 12:00AM" ,
      update-date
        str "Apr 13 2003  7:01AM" } ,
    {
      type generif ,
      text "NAT2 slow acetylation and GSTM1 null genotypes may increase
 postmenopausal breast cancer risk in long-term smoking women." ,
      version 0 ,
      refs {
        pmid 12835615 } ,
      create-date
        str "Mar  7 2004 12:00AM" ,
      update-date
        str "Apr 18 2004  7:02AM" } ,
    {
      type generif ,
      text "A slow acetylator genotype of this enzyme is associated with an
 increased risk of advanced cervical cancer." ,
      version 0 ,
      refs {
        pmid 12474054 } ,
      create-date
        str "Feb 27 2003 12:00AM" ,
      update-date
        str "Apr 13 2003  7:01AM" } ,
    {
      type generif ,
      text "Women with the GSTT1 null genotype were found to have a
 significant 3.15-fold increased risk of breast cancer (95% CI = 1.7-5.8),
 while GSTM1 and NAT2 genotypes were not associated with breast cancer risk." ,
      version 0 ,
      refs {
        pmid 12430181 } ,
      create-date
        str "Nov 25 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:01AM" } ,
    {
      type generif ,
      text "NAT2 slow genotype with NAT1 polymorphism indicates increased
 susceptibility to prostate cancer" ,
      version 0 ,
      refs {
        pmid 12355549 } ,
      create-date
        str "Oct 31 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:01AM" } ,
    {
      type generif ,
      text "NAT2 slow acetylation genotype may be a risk factor of individual
 susceptibility to rheumatoid arthritis." ,
      version 0 ,
      refs {
        pmid 12235453 } ,
      create-date
        str "Oct  7 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:01AM" } ,
    {
      type generif ,
      text "NAT2 acetylator status can influence susceptibility to breast
 cancer after exposure to tobacco smoke carcinogens; effect appears to be
 differential for active and passive smoke exposure" ,
      version 0 ,
      refs {
        pmid 12163321 } ,
      create-date
        str "Sep  7 2002 12:00AM" ,
      update-date
        str "Sep 16 2002  5:48AM" } ,
    {
      type generif ,
      text "NAT2 polymorphisms may be correlated with an increased risk of
 larynx cancer" ,
      version 0 ,
      refs {
        pmid 12037388 } ,
      create-date
        str "Aug 19 2002 12:00AM" ,
      update-date
        str "Aug 28 2002  6:15PM" } ,
    {
      type generif ,
      text "The combined effect of N-acetyltransferase 2 (NAT2) slow genotype
 and exposure to smoking is observed during the development of laryngeal
 cancer." ,
      version 0 ,
      refs {
        pmid 12015038 } ,
      create-date
        str "Aug  9 2002 12:00AM" ,
      update-date
        str "Sep 16 2002  5:48AM" } ,
    {
      type generif ,
      text "urinary excretion of
 N(2)-(beta-1-glucos-iduronyl)-2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]p
yridine relationship to activity levels of NAT2" ,
      version 0 ,
      refs {
        pmid 12016157 } ,
      create-date
        str "Jun 12 2002 12:00AM" ,
      update-date
        str "Jun 24 2002  6:31AM" } ,
    {
      type generif ,
      text "Polymorphism of the N-acetyltransferase 2 gene as a susceptibility
 risk factor for antituberculosis drug-induced hepatitis." ,
      version 0 ,
      refs {
        pmid 11915035 } ,
      create-date
        str "Apr 15 2002 12:00AM" ,
      update-date
        str "Apr 28 2002  6:17PM" } ,
    {
      type generif ,
      text "Association between bone loss in periodontal disease and
 polymorphism of N-acetyltransferase (NAT2)" ,
      version 0 ,
      refs {
        pmid 11846845 } ,
      create-date
        str "Apr  9 2002 12:00AM" ,
      update-date
        str "May 14 2002  5:48AM" } ,
    {
      type generif ,
      text "we investigated the relationship between the levels of aromatic
 DNA adducts in breast tissues and polymorphisms of the drug-metabolizing
 genes CYP1A1, NAT2, and GSTM1 in 166 women having breast cancer" ,
      version 0 ,
      refs {
        pmid 11872636 } ,
      create-date
        str "Apr  2 2002 12:00AM" ,
      update-date
        str "Apr  8 2002  3:24PM" } } ,
  unique-keys {
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        id 10 } ,
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      db "MIM" ,
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        id 243400 } } ,
  xtra-index-terms {
    "LOC10" } }
Entrezgene ::= {
  track-info {
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    create-date
      std {
        year 2003 ,
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        minute 30 ,
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    update-date
      std {
        year 2005 ,
        month 3 ,
        day 5 ,
        hour 11 ,
        minute 30 ,
        second 0 } } ,
  type pseudo ,
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      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "8" } } } ,
  gene {
    locus "AACP" ,
    desc "arylamide acetylase pseudogene" ,
    maploc "8p22" ,
    syn {
      "NATP" } ,
    locus-tag "HGNC:15" } ,
  location {
    {
      display-str "8p22" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 11 ,
    src-str2 "11" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "AACP" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "arylamide acetylase pseudogene" ,
          version 0 } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 15 } } } } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 2340091 } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "X17060" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 34995 } ,
              anchor "X17060" } } ,
          seqs {
            whole
              gi 34995 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:132838" } } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11 } } ,
  xtra-index-terms {
    "LOC11" } }
Entrezgene ::= {
  track-info {
    geneid 12 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 14 ,
        hour 13 ,
        minute 15 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "14" } } } ,
  gene {
    locus "SERPINA3" ,
    desc "serine (or cysteine) proteinase inhibitor, clade A (alpha-1
 antiproteinase, antitrypsin), member 3" ,
    maploc "14q32.1" ,
    db {
      {
        db "MIM" ,
        tag
          id 107280 } } ,
    syn {
      "ACT" ,
      "AACT" ,
      "MGC88254" } ,
    locus-tag "HGNC:16" } ,
  prot {
    name {
      "serine (or cysteine) proteinase inhibitor, clade A, member 3" ,
      "antichymotrypsin" ,
      "alpha-1-antichymotrypsin" ,
      "serine (or cysteine) proteinase inhibitor, clade A, member 3" } } ,
  summary "The protein encoded by this gene is a plasma protease inhibitor and
 member of the serine protease inhibitor class.  Polymorphisms in this protein
 appear to be tissue specific and influence protease targeting.  Variation in
 this protein's sequence have been implicated in Alzheimer's disease, and
 deficiency of this protein has been associated with liver disease.  Mutations
 have been identified in patients with Parkinson disease and chronic
 obstructive pulmonary disease." ,
  location {
    {
      display-str "14q32.1" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 12 ,
    src-str2 "12" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000014" ,
      version 7 ,
      seqs {
        int {
          from 94150523 ,
          to 94160143 ,
          strand plus ,
          id
            gi 51511730 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001085" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 94150523 ,
                to 94151173 ,
                strand plus ,
                id
                  gi 51511730 } ,
              int {
                from 94155284 ,
                to 94155557 ,
                strand plus ,
                id
                  gi 51511730 } ,
              int {
                from 94158430 ,
                to 94158580 ,
                strand plus ,
                id
                  gi 51511730 } ,
              int {
                from 94159700 ,
                to 94160143 ,
                strand plus ,
                id
                  gi 51511730 } } } ,
          seqs {
            whole
              gi 9665246 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              label "precursor" ,
              accession "NP_001076" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 94150531 ,
                    to 94151173 ,
                    strand plus ,
                    id
                      gi 51511730 } ,
                  {
                    from 94155284 ,
                    to 94155557 ,
                    strand plus ,
                    id
                      gi 51511730 } ,
                  {
                    from 94158430 ,
                    to 94158580 ,
                    strand plus ,
                    id
                      gi 51511730 } ,
                  {
                    from 94159700 ,
                    to 94159935 ,
                    strand plus ,
                    id
                      gi 51511730 } } } ,
              seqs {
                whole
                  gi 4501843 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_026437" ,
      version 11 ,
      seqs {
        int {
          from 76080523 ,
          to 76090143 ,
          strand plus ,
          id
            gi 51493278 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001085" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 76080523 ,
                to 76081173 ,
                strand plus ,
                id
                  gi 51493278 } ,
              int {
                from 76085284 ,
                to 76085557 ,
                strand plus ,
                id
                  gi 51493278 } ,
              int {
                from 76088430 ,
                to 76088580 ,
                strand plus ,
                id
                  gi 51493278 } ,
              int {
                from 76089700 ,
                to 76090143 ,
                strand plus ,
                id
                  gi 51493278 } } } ,
          seqs {
            whole
              gi 9665246 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              label "precursor" ,
              accession "NP_001076" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 76080531 ,
                    to 76081173 ,
                    strand plus ,
                    id
                      gi 51493278 } ,
                  {
                    from 76085284 ,
                    to 76085557 ,
                    strand plus ,
                    id
                      gi 51493278 } ,
                  {
                    from 76088430 ,
                    to 76088580 ,
                    strand plus ,
                    id
                      gi 51493278 } ,
                  {
                    from 76089700 ,
                    to 76089935 ,
                    strand plus ,
                    id
                      gi 51493278 } } } ,
              seqs {
                whole
                  gi 4501843 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086807" ,
      version 1 ,
      seqs {
        int {
          from 23153523 ,
          to 23163143 ,
          strand plus ,
          id
            gi 51472322 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001085" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 23153523 ,
                to 23154173 ,
                strand plus ,
                id
                  gi 51472322 } ,
              int {
                from 23158284 ,
                to 23158557 ,
                strand plus ,
                id
                  gi 51472322 } ,
              int {
                from 23161430 ,
                to 23161580 ,
                strand plus ,
                id
                  gi 51472322 } ,
              int {
                from 23162700 ,
                to 23163143 ,
                strand plus ,
                id
                  gi 51472322 } } } ,
          seqs {
            whole
              gi 9665246 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              label "precursor" ,
              accession "NP_001076" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 23153531 ,
                    to 23154173 ,
                    strand plus ,
                    id
                      gi 51472322 } ,
                  {
                    from 23158284 ,
                    to 23158557 ,
                    strand plus ,
                    id
                      gi 51472322 } ,
                  {
                    from 23161430 ,
                    to 23161580 ,
                    strand plus ,
                    id
                      gi 51472322 } ,
                  {
                    from 23162700 ,
                    to 23162935 ,
                    strand plus ,
                    id
                      gi 51472322 } } } ,
              seqs {
                whole
                  gi 4501843 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "SERPINA3" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "serine (or cysteine) proteinase inhibitor, clade A (alpha-1
 antiproteinase, antitrypsin), member 3" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "GOA" ,
          url "http://www.ebi.ac.uk/GOA/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9880565 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 3677 } ,
                  anchor "DNA binding" ,
                  post-text "evidence: IC" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9880565 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 30569 } ,
                  anchor "chymotrypsin inhibitor activity" ,
                  post-text "evidence: NAS" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12709365 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5515 } ,
                  anchor "protein binding" ,
                  post-text "evidence: IPI" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4867 } ,
                  anchor "serine-type endopeptidase inhibitor activity" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6953 } ,
                  anchor "acute-phase response" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12475184 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6954 } ,
                  anchor "inflammatory response" ,
                  post-text "evidence: NAS" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 11835318 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 19216 } ,
                  anchor "regulation of lipid metabolism" ,
                  post-text "evidence: NAS" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6810 } ,
                  anchor "transport" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9880565 ,
                pmid 14718574 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5576 } ,
                  anchor "extracellular region" ,
                  post-text "evidence: NAS" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9880565 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5622 } ,
                  anchor "intracellular" ,
                  post-text "evidence: NAS" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5634 } ,
                  anchor "nucleus" ,
                  post-text "evidence: IEA" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 40658 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=14&
MAPS=genes-r-org/rat-chr/human%3A14,genes-r-org/mouse-chr/human%3A14,genes-r-o
rg/human-chr14&query=e%3A12[id]+AND+gene[obj_type]&QSTR=serpina3&cmd=focus&fil
l=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 16 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 15546506 ,
        pmid 15542006 ,
        pmid 15530656 ,
        pmid 15014966 ,
        pmid 14718574 ,
        pmid 14702039 ,
        pmid 14668352 ,
        pmid 12709365 ,
        pmid 12600202 ,
        pmid 12477932 ,
        pmid 12475184 ,
        pmid 12324297 ,
        pmid 12023832 ,
        pmid 11992569 ,
        pmid 11959399 ,
        pmid 11936240 ,
        pmid 11835318 ,
        pmid 11798857 ,
        pmid 11735417 ,
        pmid 11692021 ,
        pmid 11317942 ,
        pmid 11289720 ,
        pmid 11274154 ,
        pmid 11096092 ,
        pmid 10829039 ,
        pmid 10759471 ,
        pmid 10660528 ,
        pmid 10512690 ,
        pmid 10228625 ,
        pmid 10048303 ,
        pmid 9880565 ,
        pmid 9824262 ,
        pmid 9698370 ,
        pmid 9635374 ,
        pmid 9580375 ,
        pmid 9428387 ,
        pmid 9261179 ,
        pmid 9042371 ,
        pmid 8849841 ,
        pmid 8739078 ,
        pmid 8732755 ,
        pmid 8718849 ,
        pmid 8376411 ,
        pmid 8365378 ,
        pmid 8267879 ,
        pmid 8244391 ,
        pmid 8226889 ,
        pmid 8216224 ,
        pmid 8011628 ,
        pmid 7966721 ,
        pmid 7924407 ,
        pmid 7873202 ,
        pmid 7759598 ,
        pmid 7588564 ,
        pmid 7528097 ,
        pmid 6762318 ,
        pmid 6687683 ,
        pmid 6606438 ,
        pmid 6556193 ,
        pmid 6547997 ,
        pmid 3637050 ,
        pmid 3492865 ,
        pmid 3490907 ,
        pmid 3485824 ,
        pmid 3260956 ,
        pmid 3257719 ,
        pmid 3028924 ,
        pmid 2945424 ,
        pmid 2456771 ,
        pmid 2435303 ,
        pmid 2432851 ,
        pmid 2404007 ,
        pmid 2190106 ,
        pmid 1618300 ,
        pmid 1351206 ,
        pmid 1311327 } } ,
    {
      type comment ,
      heading "Phenotypes" ,
      version 0 ,
      comment {
        {
          type phenotype ,
          text "Alpha-1-antichymotrypsin deficiency" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  id 107280 } ,
              anchor "MIM: 107280" } } } ,
        {
          type phenotype ,
          text "Cerebrovascular disease, occlusive" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  id 107280 } ,
              anchor "MIM: 107280" } } } } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 32177 } ,
              anchor "RH1625" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "RH77711" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "stSG1393" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 37467 } ,
              anchor "SHGC-32982" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "EST128561" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH32590" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH53830" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "SGC32982" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 64155 } ,
              anchor "D14S845" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "GDB:588356" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH53900" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "UTR-04554" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "WI-7103" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 66238 } ,
              anchor "G31126" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "SHGC-19718" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 74665 } ,
              anchor "RH78280" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "stSG41027" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 86678 } ,
              anchor "RH91507" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "stSG44830" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 272387 } ,
              anchor "PMC27764P1" ,
              post-text "(e-PCR)" } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_001085" ,
          version 3 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 50659079 } ,
              anchor "NM_001085" } } ,
          seqs {
            whole
              gi 50659079 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_001076" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 50659080 } ,
                  anchor "NP_001076" ,
                  post-text "serine (or cysteine) proteinase inhibitor, clade
 A, member 3 precursor" } } ,
              seqs {
                whole
                  gi 50659080 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 50659080 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 28234 } ,
                          anchor "cd02056: alpha-1-antitrypsin_like;
 alpha-1-antitrypsin_like" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 52 - 417  Blast Score: 1367" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "BC003559,BG565041" } ,
                  anchor "BC003559,BG565041" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "X00947" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 28331 } ,
              anchor "X00947" } } ,
          seqs {
            whole
              gi 28331 } ,
          products {
            {
              type peptide ,
              accession "CAA25459" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 28332 } ,
                  anchor "CAA25459" } } ,
              seqs {
                whole
                  gi 28332 } } } } ,
        {
          type genomic ,
          heading "Genomic" ,
          accession "X68733" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 439137 } ,
              anchor "X68733" } } ,
          seqs {
            whole
              gi 439137 } ,
          products {
            {
              type peptide ,
              accession "CAA48671" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 1340142 } ,
                  anchor "CAA48671" } } ,
              seqs {
                whole
                  gi 1340142 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AB209060" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 62087699 } ,
              anchor "AB209060" } } ,
          seqs {
            whole
              gi 62087699 } ,
          products {
            {
              type peptide ,
              accession "BAD92297" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 62087700 } ,
                  anchor "BAD92297" } } ,
              seqs {
                whole
                  gi 62087700 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AF089747" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 4165889 } ,
              anchor "AF089747" } } ,
          seqs {
            whole
              gi 4165889 } ,
          products {
            {
              type peptide ,
              accession "AAD08810" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 4165890 } ,
                  anchor "AAD08810" } } ,
              seqs {
                whole
                  gi 4165890 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK093049" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 21751790 } ,
              anchor "AK093049" } } ,
          seqs {
            whole
              gi 21751790 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK096120" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 21755531 } ,
              anchor "AK096120" } } ,
          seqs {
            whole
              gi 21755531 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
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            {
              src {
                db "Nucleotide" ,
                tag
                  id 34528556 } ,
              anchor "AK123091" } } ,
          seqs {
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              gi 34528556 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
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          accession "BC003559" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 13097704 } ,
              anchor "BC003559" } } ,
          seqs {
            whole
              gi 13097704 } ,
          products {
            {
              type peptide ,
              accession "AAH03559" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 13097705 } ,
                  anchor "AAH03559" } } ,
              seqs {
                whole
                  gi 13097705 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC010530" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 14714765 } ,
              anchor "BC010530" } } ,
          seqs {
            whole
              gi 14714765 } ,
          products {
            {
              type peptide ,
              accession "AAH10530" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 14714766 } ,
                  anchor "AAH10530" } } ,
              seqs {
                whole
                  gi 14714766 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
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          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 15341984 } ,
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          seqs {
            whole
              gi 15341984 } ,
          products {
            {
              type peptide ,
              accession "AAH13189" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 15341985 } ,
                  anchor "AAH13189" } } ,
              seqs {
                whole
                  gi 15341985 } } } } ,
        {
          type mRNA ,
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            {
              src {
                db "Nucleotide" ,
                tag
                  id 21961492 } ,
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            whole
              gi 21961492 } ,
          products {
            {
              type peptide ,
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                {
                  src {
                    db "Protein" ,
                    tag
                      id 21961493 } ,
                  anchor "AAH34554" } } ,
              seqs {
                whole
                  gi 21961493 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC070265" ,
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            {
              src {
                db "Nucleotide" ,
                tag
                  id 47124537 } ,
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          seqs {
            whole
              gi 47124537 } ,
          products {
            {
              type peptide ,
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              version 1 ,
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                {
                  src {
                    db "Protein" ,
                    tag
                      id 47124538 } ,
                  anchor "AAH70265" } } ,
              seqs {
                whole
                  gi 47124538 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BG565041" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 13572694 } ,
              anchor "BG565041" } } ,
          seqs {
            whole
              gi 13572694 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "J05176" ,
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          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 177932 } ,
              anchor "J05176" } } ,
          seqs {
            whole
              gi 177932 } ,
          products {
            {
              type peptide ,
              accession "AAA51560" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 177933 } ,
                  anchor "AAA51560" } } ,
              seqs {
                whole
                  gi 177933 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "K01500" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 177808 } ,
              anchor "K01500" } } ,
          seqs {
            whole
              gi 177808 } ,
          products {
            {
              type peptide ,
              accession "AAA51543" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 177809 } ,
                  anchor "AAA51543" } } ,
              seqs {
                whole
                  gi 177809 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "M18906" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 177928 } ,
              anchor "M18906" } } ,
          seqs {
            whole
              gi 177928 } ,
          products {
            {
              type peptide ,
              accession "AAA51559" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 177931 } ,
                  anchor "AAA51559" } } ,
              seqs {
                whole
                  gi 177931 } } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "P01011" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 112874 } ,
                  anchor "P01011" } } ,
              seqs {
                whole
                  gi 112874 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "12" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_026437.11&gene=SERPINA3&lid=12&from=76080524&to=76090144" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "12" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96
06&contig=NT_026437.11&gene=SERPINA3&lid=12" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Hs.534293" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Hs.534293" } ,
              anchor "Hs.534293" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=53
4293" } } } ,
        {
          type comment ,
          text "MIM" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  str "107280" } ,
              anchor "107280" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "12" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
12[loc]&TAXID=9606" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "AceView" ,
                tag
                  id 12 } ,
              anchor "AceView" ,
              url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l
ocusid&org=9606&l=12" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:118955" } } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=AK093
049" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
AK093049" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "KEGG" ,
                tag
                  str "" } ,
              url "http://www.genome.ad.jp/dbget-bin/www_bget?hsa:12" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGC" ,
                tag
                  str "BC003559,BC010530,BC034554" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC003559
,BC010530,BC034554" } } } } } ,
    {
      type comment ,
      heading "Pathways" ,
      version 0 ,
      comment {
        {
          type comment ,
          text "KEGG pathway: Alzheimer's disease" ,
          version 0 ,
          source {
            {
              src {
                db "05010" ,
                tag
                  str "05010" } ,
              anchor "05010" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa05010+12" } } } } } ,
    {
      type generif ,
      text "overexpression of ACT by astrocytes could thus contribute to
 increased beta-amyloid fibril formation in Alzheimer's disease" ,
      version 0 ,
      refs {
        pmid 15530656 } ,
      create-date
        str "Jan 29 2005 10:01AM" ,
      update-date
        str "Jan 29 2005  1:54PM" } ,
    {
      type generif ,
      text "Multivariate analysis showed that ACT mRNA level, but not STC2
 mRNA level, in HR-positive patients, was a significant prognostic factor (P =
 0.042), which was independent of tumor size and lymph node metastases." ,
      version 0 ,
      refs {
        pmid 15546506 } ,
      create-date
        str "Jan 15 2005 10:01AM" ,
      update-date
        str "Jan 15 2005  4:35PM" } ,
    {
      type generif ,
      text "Alpha1-antichymotrypsin-AA may confer a modest protection against
 developing early-onset Parkinson disease in women" ,
      version 0 ,
      refs {
        pmid 15542006 } ,
      create-date
        str "Jan 15 2005 10:01AM" ,
      update-date
        str "Jan 15 2005  1:01PM" } ,
    {
      type generif ,
      text "Polymeric AACT specifically seeds the polymerization of native
 protein by a serpin-dependent process that occurs under physiological
 conditions and may be important in the deposition of AACT in plaques in
 patients with Alzheimer's disease." ,
      version 0 ,
      refs {
        pmid 12600202 } ,
      create-date
        str "May 26 2003 12:00AM" ,
      update-date
        str "Jun  1 2003  7:01AM" } ,
    {
      type generif ,
      text "alpha(1)-antichymotrypsin polymorphism: a risk factor for
 hemorrhagic stroke in normotensive subjects." ,
      version 0 ,
      refs {
        pmid 11692021 } ,
      create-date
        str "Mar  5 2003 12:00AM" ,
      update-date
        str "Mar 23 2003  7:01AM" } ,
    {
      type generif ,
      text "alpha(1)-antitrypsin and antichymotrypsin are produced by the
 mammary gland and are present in milk in relatively high amounts in early
 lactation" ,
      version 0 ,
      refs {
        pmid 12324297 } ,
      create-date
        str "Oct 11 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:01AM" } ,
    {
      type generif ,
      text "Gene regulation of the serine proteinase inhibitors
 alpha1-antitrypsin and alpha1-antichymotrypsin." ,
      version 0 ,
      refs {
        pmid 12023832 } ,
      create-date
        str "Oct  9 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:01AM" } ,
    {
      type generif ,
      text "data suggested that the ApoE epsilon2/epsilon4 genotype might be a
 susceptibility variant of moderate effect for sporadic idiopathic Parkinson
 disease in our samples, whereas the ACT gene signal peptide polymorphism
 might not" ,
      version 0 ,
      refs {
        pmid 11992569 } ,
      create-date
        str "Sep 26 2002 12:00AM" ,
      update-date
        str "Oct  7 2002  8:10AM" } ,
    {
      type generif ,
      text "no association seen between alpha 1-antichymotrypsin and time to
 psychosis in Alzheimer's disease" ,
      version 0 ,
      refs {
        pmid 11936240 } ,
      create-date
        str "Aug 28 2002 12:00AM" ,
      update-date
        str "Sep 16 2002  5:48AM" } ,
    {
      type generif ,
      text "significantly higher in plasma of Alzheimer patients compared to
 controls" ,
      version 0 ,
      refs {
        pmid 11959399 } ,
      create-date
        str "Jul 22 2002 12:00AM" ,
      update-date
        str "Jul 29 2002  6:27PM" } ,
    {
      type generif ,
      text "A25G and G39A substitutions in the AACT gene are probably one of
 the risk factors to Alzheimer's disease (AD) in Han Chinese." ,
      version 0 ,
      refs {
        pmid 11798857 } ,
      create-date
        str "Apr  7 2002 12:00AM" ,
      update-date
        str "Apr 13 2002  5:25PM" } ,
    {
      type generif ,
      heading "Interactions" ,
      version 0 ,
      comment {
        {
          type generif ,
          text "Alpha-1 ACT interacts with and inhibits cathepsin G." ,
          version 0 ,
          refs {
            pmid 15131125 } ,
          source {
            {
              src {
                db "BIND" ,
                tag
                  id 149291 } ,
              anchor "BIND" } } ,
          comment {
            {
              type comment ,
              label "SERPINA3" ,
              accession "NP_001076" ,
              version 1 } ,
            {
              type comment ,
              label "CTSG" ,
              accession "NP_001902" ,
              version 1 ,
              source {
                {
                  src {
                    db "GeneID" ,
                    tag
                      id 1511 } } } } } ,
          create-date
            str "2005-01-21 20:10 EDT" ,
          update-date
            str "2005-01-21 20:19 EDT" } ,
        {
          type generif ,
          text "LRP interacts with alpha-1-ACT." ,
          version 0 ,
          refs {
            pmid 15131125 } ,
          source {
            {
              src {
                db "BIND" ,
                tag
                  id 149296 } ,
              anchor "BIND" } } ,
          comment {
            {
              type comment ,
              label "SERPINA3" ,
              accession "NP_001076" ,
              version 1 } ,
            {
              type comment ,
              label "LRP1" ,
              accession "NP_002323" ,
              version 1 ,
              source {
                {
                  src {
                    db "GeneID" ,
                    tag
                      id 4035 } } } } } ,
          create-date
            str "2005-01-21 20:10 EDT" ,
          update-date
            str "2005-01-21 20:19 EDT" } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 12 } ,
    {
      db "MIM" ,
      tag
        id 107280 } } ,
  xtra-index-terms {
    "LOC12" } ,
  xtra-properties {
    {
      tag "PROP" ,
      value "phenotype" } } }
Entrezgene ::= {
  track-info {
    geneid 13 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 3 ,
        day 5 ,
        hour 11 ,
        minute 30 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "3" } } } ,
  gene {
    locus "AADAC" ,
    desc "arylacetamide deacetylase (esterase)" ,
    maploc "3q21.3-q25.2" ,
    db {
      {
        db "MIM" ,
        tag
          id 600338 } } ,
    syn {
      "DAC" } ,
    locus-tag "HGNC:17" } ,
  prot {
    name {
      "arylacetamide deacetylase" } } ,
  summary "Microsomal arylacetamide deacetylase competes against the activity
 of cytosolic arylamine N-acetyltransferase, which catalyzes one of the
 initial biotransformation pathways for arylamine and heterocyclic amine
 carcinogens" ,
  location {
    {
      display-str "3q21.3-q25.2" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 13 ,
    src-str2 "13" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000003" ,
      version 9 ,
      seqs {
        int {
          from 153014563 ,
          to 153028971 ,
          strand plus ,
          id
            gi 51511463 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001086" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 153014563 ,
                to 153014785 ,
                strand plus ,
                id
                  gi 51511463 } ,
              int {
                from 153017851 ,
                to 153018073 ,
                strand plus ,
                id
                  gi 51511463 } ,
              int {
                from 153020868 ,
                to 153020937 ,
                strand plus ,
                id
                  gi 51511463 } ,
              int {
                from 153025148 ,
                to 153025319 ,
                strand plus ,
                id
                  gi 51511463 } ,
              int {
                from 153028061 ,
                to 153028971 ,
                strand plus ,
                id
                  gi 51511463 } } } ,
          seqs {
            whole
              gi 4557226 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001077" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 153014648 ,
                    to 153014785 ,
                    strand plus ,
                    id
                      gi 51511463 } ,
                  {
                    from 153017851 ,
                    to 153018073 ,
                    strand plus ,
                    id
                      gi 51511463 } ,
                  {
                    from 153020868 ,
                    to 153020937 ,
                    strand plus ,
                    id
                      gi 51511463 } ,
                  {
                    from 153025148 ,
                    to 153025319 ,
                    strand plus ,
                    id
                      gi 51511463 } ,
                  {
                    from 153028061 ,
                    to 153028657 ,
                    strand plus ,
                    id
                      gi 51511463 } } } ,
              seqs {
                whole
                  gi 4557227 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "3.1.1.-" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "3.1.1.-" } } } } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_005612" ,
      version 14 ,
      seqs {
        int {
          from 58027019 ,
          to 58041427 ,
          strand plus ,
          id
            gi 37550867 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001086" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 58027019 ,
                to 58027241 ,
                strand plus ,
                id
                  gi 37550867 } ,
              int {
                from 58030307 ,
                to 58030529 ,
                strand plus ,
                id
                  gi 37550867 } ,
              int {
                from 58033324 ,
                to 58033393 ,
                strand plus ,
                id
                  gi 37550867 } ,
              int {
                from 58037604 ,
                to 58037775 ,
                strand plus ,
                id
                  gi 37550867 } ,
              int {
                from 58040517 ,
                to 58041427 ,
                strand plus ,
                id
                  gi 37550867 } } } ,
          seqs {
            whole
              gi 4557226 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001077" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 58027104 ,
                    to 58027241 ,
                    strand plus ,
                    id
                      gi 37550867 } ,
                  {
                    from 58030307 ,
                    to 58030529 ,
                    strand plus ,
                    id
                      gi 37550867 } ,
                  {
                    from 58033324 ,
                    to 58033393 ,
                    strand plus ,
                    id
                      gi 37550867 } ,
                  {
                    from 58037604 ,
                    to 58037775 ,
                    strand plus ,
                    id
                      gi 37550867 } ,
                  {
                    from 58040517 ,
                    to 58041113 ,
                    strand plus ,
                    id
                      gi 37550867 } } } ,
              seqs {
                whole
                  gi 4557227 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "3.1.1.-" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "3.1.1.-" } } } } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086641" ,
      version 1 ,
      seqs {
        int {
          from 24339789 ,
          to 24354221 ,
          strand plus ,
          id
            gi 51464125 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001086" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 24339789 ,
                to 24340011 ,
                strand plus ,
                id
                  gi 51464125 } ,
              int {
                from 24343078 ,
                to 24343300 ,
                strand plus ,
                id
                  gi 51464125 } ,
              int {
                from 24346094 ,
                to 24346163 ,
                strand plus ,
                id
                  gi 51464125 } ,
              int {
                from 24350369 ,
                to 24350540 ,
                strand plus ,
                id
                  gi 51464125 } ,
              int {
                from 24353311 ,
                to 24354221 ,
                strand plus ,
                id
                  gi 51464125 } } } ,
          seqs {
            whole
              gi 4557226 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001077" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 24339874 ,
                    to 24340011 ,
                    strand plus ,
                    id
                      gi 51464125 } ,
                  {
                    from 24343078 ,
                    to 24343300 ,
                    strand plus ,
                    id
                      gi 51464125 } ,
                  {
                    from 24346094 ,
                    to 24346163 ,
                    strand plus ,
                    id
                      gi 51464125 } ,
                  {
                    from 24350369 ,
                    to 24350540 ,
                    strand plus ,
                    id
                      gi 51464125 } ,
                  {
                    from 24353311 ,
                    to 24353907 ,
                    strand plus ,
                    id
                      gi 51464125 } } } ,
              seqs {
                whole
                  gi 4557227 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "3.1.1.-" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "3.1.1.-" } } } } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "AADAC" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "arylacetamide deacetylase (esterase)" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "GOA" ,
          url "http://www.ebi.ac.uk/GOA/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9665742 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 19213 } ,
                  anchor "deacetylase activity" ,
                  post-text "evidence: IDA" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8152 } ,
                  anchor "metabolism" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 10318829 ,
                pmid 15152005 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5789 } ,
                  anchor "endoplasmic reticulum membrane" ,
                  post-text "evidence: IDA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16021 } ,
                  anchor "integral to membrane" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 8063807 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5792 } ,
                  anchor "microsome" ,
                  post-text "evidence: TAS" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 37436 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=3&M
APS=genes-r-org/rat-chr/human%3A3,genes-r-org/mouse-chr/human%3A3,genes-r-org/
human-chr3&query=e%3A13[id]+AND+gene[obj_type]&QSTR=aadac&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 17 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 15152005 ,
        pmid 12721789 ,
        pmid 12477932 ,
        pmid 10318829 ,
        pmid 9665742 ,
        pmid 9299245 ,
        pmid 8063807 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 13170 } ,
              anchor "STS-L32179" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "RH41545" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "sts-L32179" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 18863 } ,
              anchor "D3S4189" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "SHGC-9733" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 24707 } ,
              anchor "RH36344" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "stSG13141" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 136046 } ,
              anchor "RH124029" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "SHGC-105511" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_001086" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 4557226 } ,
              anchor "NM_001086" } } ,
          seqs {
            whole
              gi 4557226 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_001077" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 4557227 } ,
                  anchor "NP_001077" ,
                  post-text "arylacetamide deacetylase" } } ,
              seqs {
                whole
                  gi 4557227 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 4557227 } ,
                      pre-text "(2)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 10527 } ,
                          anchor "COG0657: Aes; Esterase/lipase [Lipid
 metabolism]" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 33 - 399  Blast Score: 380" ,
                          version 0 } } } ,
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 16555 } ,
                          anchor "cd00312: Esterase_lipase; Esterases and
 lipases (includes fungal lipases, cholinesterases, etc" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 91 - 203  Blast Score: 144" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "L32179" } ,
                  anchor "L32179" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC020706" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 18088402 } ,
              anchor "BC020706" } } ,
          seqs {
            whole
              gi 18088402 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC032309" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 21595550 } ,
              anchor "BC032309" } } ,
          seqs {
            whole
              gi 21595550 } ,
          products {
            {
              type peptide ,
              accession "AAH32309" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 21595551 } ,
                  anchor "AAH32309" } } ,
              seqs {
                whole
                  gi 21595551 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "L32179" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 537513 } ,
              anchor "L32179" } } ,
          seqs {
            whole
              gi 537513 } ,
          products {
            {
              type peptide ,
              accession "AAA35551" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 537514 } ,
                  anchor "AAA35551" } } ,
              seqs {
                whole
                  gi 537514 } } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "P22760" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 57015294 } ,
                  anchor "P22760" } } ,
              seqs {
                whole
                  gi 57015294 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "13" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_005612.14&gene=AADAC&lid=13&from=58027020&to=58041428" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "13" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96
06&contig=NT_005612.14&gene=AADAC&lid=13" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Hs.506908" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Hs.506908" } ,
              anchor "Hs.506908" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=50
6908" } } } ,
        {
          type comment ,
          text "MIM" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  str "600338" } ,
              anchor "600338" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "13" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
13[loc]&TAXID=9606" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "AceView" ,
                tag
                  id 13 } ,
              anchor "AceView" ,
              url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l
ocusid&org=9606&l=13" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:392587" } } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=BC032
309" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
BC032309" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "KEGG" ,
                tag
                  str "" } ,
              url "http://www.genome.ad.jp/dbget-bin/www_bget?hsa:13" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGC" ,
                tag
                  str "BC032309" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC032309" } } } } } ,
    {
      type comment ,
      heading "Pathways" ,
      version 0 ,
      comment {
        {
          type comment ,
          text "KEGG pathway: Butanoate metabolism" ,
          version 0 ,
          source {
            {
              src {
                db "00650" ,
                tag
                  str "00650" } ,
              anchor "00650" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa00650+13" } } } ,
        {
          type comment ,
          text "KEGG pathway: Alkaloid biosynthesis II" ,
          version 0 ,
          source {
            {
              src {
                db "00960" ,
                tag
                  str "00960" } ,
              anchor "00960" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa00960+13" } } } ,
        {
          type comment ,
          text "KEGG pathway: 2,4-Dichlorobenzoate degradation" ,
          version 0 ,
          source {
            {
              src {
                db "00623" ,
                tag
                  str "00623" } ,
              anchor "00623" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa00623+13" } } } ,
        {
          type comment ,
          text "KEGG pathway: Pentose and glucuronate interconversions" ,
          version 0 ,
          source {
            {
              src {
                db "00040" ,
                tag
                  str "00040" } ,
              anchor "00040" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa00040+13" } } } ,
        {
          type comment ,
          text "KEGG pathway: Glycosylphosphatidylinositol(GPI)-anchor
 biosynthesis" ,
          version 0 ,
          source {
            {
              src {
                db "00563" ,
                tag
                  str "00563" } ,
              anchor "00563" ,
              url "http://www.genome.jp/dbget-bin/show_pathway?hsa00563+13" } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 13 } ,
    {
      db "MIM" ,
      tag
        id 600338 } } ,
  xtra-index-terms {
    "LOC13" } }
Entrezgene ::= {
  track-info {
    geneid 14 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 14 ,
        hour 13 ,
        minute 15 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "2" } } } ,
  gene {
    locus "AAMP" ,
    desc "angio-associated, migratory cell protein" ,
    maploc "2q35" ,
    db {
      {
        db "MIM" ,
        tag
          id 603488 } } ,
    locus-tag "HGNC:18" } ,
  prot {
    name {
      "angio-associated, migratory cell protein" } } ,
  summary "The gene product is an immunoglobulin-type protein. It is found to
 be expressed strongly in endothelial cells, cytotrophoblasts, and poorly
 differentiated colon adenocarcinoma cells found in lymphatics. The protein
 contains a heparin-binding domain and mediates heparin-sensitive cell
 adhesion." ,
  location {
    {
      display-str "2q35" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 14 ,
    src-str2 "14" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000002" ,
      version 9 ,
      seqs {
        int {
          from 218954357 ,
          to 218960364 ,
          strand minus ,
          id
            gi 51511462 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001087" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 218954357 ,
                to 218954835 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218955247 ,
                to 218955401 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218955598 ,
                to 218955688 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218955806 ,
                to 218955909 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218956058 ,
                to 218956173 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218956291 ,
                to 218956374 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218956670 ,
                to 218956814 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218957074 ,
                to 218957213 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218957721 ,
                to 218957840 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218959609 ,
                to 218959761 ,
                strand minus ,
                id
                  gi 51511462 } ,
              int {
                from 218960193 ,
                to 218960364 ,
                strand minus ,
                id
                  gi 51511462 } } } ,
          seqs {
            whole
              gi 4557228 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001078" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 218954760 ,
                    to 218954835 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218955247 ,
                    to 218955401 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218955598 ,
                    to 218955688 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218955806 ,
                    to 218955909 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218956058 ,
                    to 218956173 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218956291 ,
                    to 218956374 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218956670 ,
                    to 218956814 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218957074 ,
                    to 218957213 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218957721 ,
                    to 218957840 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218959609 ,
                    to 218959761 ,
                    strand minus ,
                    id
                      gi 51511462 } ,
                  {
                    from 218960193 ,
                    to 218960364 ,
                    strand minus ,
                    id
                      gi 51511462 } } } ,
              seqs {
                whole
                  gi 4557229 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_005403" ,
      version 15 ,
      seqs {
        int {
          from 69338267 ,
          to 69344274 ,
          strand minus ,
          id
            gi 51461028 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001087" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 69338267 ,
                to 69338745 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69339157 ,
                to 69339311 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69339508 ,
                to 69339598 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69339716 ,
                to 69339819 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69339968 ,
                to 69340083 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69340201 ,
                to 69340284 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69340580 ,
                to 69340724 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69340984 ,
                to 69341123 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69341631 ,
                to 69341750 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69343519 ,
                to 69343671 ,
                strand minus ,
                id
                  gi 51461028 } ,
              int {
                from 69344103 ,
                to 69344274 ,
                strand minus ,
                id
                  gi 51461028 } } } ,
          seqs {
            whole
              gi 4557228 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001078" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 69338670 ,
                    to 69338745 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69339157 ,
                    to 69339311 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69339508 ,
                    to 69339598 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69339716 ,
                    to 69339819 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69339968 ,
                    to 69340083 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69340201 ,
                    to 69340284 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69340580 ,
                    to 69340724 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69340984 ,
                    to 69341123 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69341631 ,
                    to 69341750 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69343519 ,
                    to 69343671 ,
                    strand minus ,
                    id
                      gi 51461028 } ,
                  {
                    from 69344103 ,
                    to 69344274 ,
                    strand minus ,
                    id
                      gi 51461028 } } } ,
              seqs {
                whole
                  gi 4557229 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_086634" ,
      version 1 ,
      seqs {
        int {
          from 23772483 ,
          to 23778490 ,
          strand minus ,
          id
            gi 51463854 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001087" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 23772483 ,
                to 23772961 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23773373 ,
                to 23773527 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23773724 ,
                to 23773814 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23773932 ,
                to 23774035 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23774184 ,
                to 23774299 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23774417 ,
                to 23774500 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23774796 ,
                to 23774940 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23775200 ,
                to 23775339 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23775847 ,
                to 23775966 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23777735 ,
                to 23777887 ,
                strand minus ,
                id
                  gi 51463854 } ,
              int {
                from 23778319 ,
                to 23778490 ,
                strand minus ,
                id
                  gi 51463854 } } } ,
          seqs {
            whole
              gi 4557228 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001078" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 23772886 ,
                    to 23772961 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23773373 ,
                    to 23773527 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23773724 ,
                    to 23773814 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23773932 ,
                    to 23774035 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23774184 ,
                    to 23774299 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23774417 ,
                    to 23774500 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23774796 ,
                    to 23774940 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23775200 ,
                    to 23775339 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23775847 ,
                    to 23775966 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23777735 ,
                    to 23777887 ,
                    strand minus ,
                    id
                      gi 51463854 } ,
                  {
                    from 23778319 ,
                    to 23778490 ,
                    strand minus ,
                    id
                      gi 51463854 } } } ,
              seqs {
                whole
                  gi 4557229 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "AAMP" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "angio-associated, migratory cell protein" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "GOA" ,
          url "http://www.ebi.ac.uk/GOA/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 7743515 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8201 } ,
                  anchor "heparin binding" ,
                  post-text "evidence: TAS" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6928 } ,
                  anchor "cell motility" ,
                  post-text "evidence: NR" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 846 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=2&M
APS=genes-r-org/rat-chr/human%3A2,genes-r-org/mouse-chr/human%3A2,genes-r-org/
human-chr2&query=e%3A14[id]+AND+gene[obj_type]&QSTR=aamp&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "HGNC" ,
            tag
              id 18 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 12477932 ,
        pmid 11969303 ,
        pmid 10329261 ,
        pmid 8660919 ,
        pmid 7743515 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 52581 } ,
              anchor "SGC31591" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "CM4.18" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "GC" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "RH23156" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "STS4-18" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_001087" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 55743074 } ,
              anchor "NM_001087" } } ,
          seqs {
            whole
              gi 55743074 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_001078" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 55743075 } ,
                  anchor "NP_001078" ,
                  post-text "angio-associated, migratory cell protein" } } ,
              seqs {
                whole
                  gi 55743075 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 55743075 } ,
                      pre-text "(2)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5398 } ,
                          anchor "cd00200: WD40; WD40 domain, found in a
 number of eukaryotic proteins that cover a wide variety of functions
 including adaptor/regulatory modules in signal transduction, pre-mRNA
 processing and cytoskeleton assembly" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 86 - 386  Blast Score: 457" ,
                          version 0 } ,
                        {
                          type other ,
                          text "Location: 325 - 430  Blast Score: 176" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "BG534787,CN277005,M95627" } ,
                  anchor "BG534787,CN277005,M95627" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AB209790" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 62089165 } ,
              anchor "AB209790" } } ,
          seqs {
            whole
              gi 62089165 } ,
          products {
            {
              type peptide ,
              accession "BAD93027" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 62089166 } ,
                  anchor "BAD93027" } } ,
              seqs {
                whole
                  gi 62089166 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK131047" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 34528300 } ,
              anchor "AK131047" } } ,
          seqs {
            whole
              gi 34528300 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC008809" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 39644831 } ,
              anchor "BC008809" } } ,
          seqs {
            whole
              gi 39644831 } ,
          products {
            {
              type peptide ,
              accession "AAH08809" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 39644832 } ,
                  anchor "AAH08809" } } ,
              seqs {
                whole
                  gi 39644832 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC014122" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 33874729 } ,
              anchor "BC014122" } } ,
          seqs {
            whole
              gi 33874729 } ,
          products {
            {
              type peptide ,
              accession "AAH14122" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 33874730 } ,
                  anchor "AAH14122" } } ,
              seqs {
                whole
                  gi 33874730 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC020244" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 18044383 } ,
              anchor "BC020244" } } ,
          seqs {
            whole
              gi 18044383 } ,
          products {
            {
              type peptide ,
              accession "AAH20244" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 18044384 } ,
                  anchor "AAH20244" } } ,
              seqs {
                whole
                  gi 18044384 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC039866" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 25123215 } ,
              anchor "BC039866" } } ,
          seqs {
            whole
              gi 25123215 } ,
          products {
            {
              type peptide ,
              accession "AAH39866" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 56200511 } ,
                  anchor "AAH39866" } } ,
              seqs {
                whole
                  gi 56200511 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "CR456755" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 48145626 } ,
              anchor "CR456755" } } ,
          seqs {
            whole
              gi 48145626 } ,
          products {
            {
              type peptide ,
              accession "CAG33036" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 48145627 } ,
                  anchor "CAG33036" } } ,
              seqs {
                whole
                  gi 48145627 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "M95627" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 870802 } ,
              anchor "M95627" } } ,
          seqs {
            whole
              gi 870802 } ,
          products {
            {
              type peptide ,
              accession "AAA68889" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 870803 } ,
                  anchor "AAA68889" } } ,
              seqs {
                whole
                  gi 870803 } } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "Q13685" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 3121739 } ,
                  anchor "Q13685" } } ,
              seqs {
                whole
                  gi 3121739 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "14" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=9606&conti
g=NT_005403.15&gene=AAMP&lid=14&from=69338268&to=69344275" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "14" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=96
06&contig=NT_005403.15&gene=AAMP&lid=14" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Hs.83347" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Hs.83347" } ,
              anchor "Hs.83347" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=83
347" } } } ,
        {
          type comment ,
          text "MIM" ,
          version 0 ,
          source {
            {
              src {
                db "MIM" ,
                tag
                  str "603488" } ,
              anchor "603488" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "14" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
14[loc]&TAXID=9606" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "AceView" ,
                tag
                  id 14 } ,
              anchor "AceView" ,
              url "http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=l
ocusid&org=9606&l=14" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "GDB" ,
                tag
                  str "GDB:4573993" } } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Homo_sapiens/contigview?geneid=AB209
790" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=
AB209790" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGC" ,
                tag
                  str "BC014122" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Hs&LIST=BC014122" } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 14 } ,
    {
      db "MIM" ,
      tag
        id 603488 } } ,
  xtra-index-terms {
    "LOC14" } }
Entrezgene ::= {
  track-info {
    geneid 15 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 20 ,
        minute 30 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 14 ,
        hour 13 ,
        minute 15 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Homo sapiens" ,
      common "human" ,
      db {
        {
          db "taxon" ,
          tag
            id 9606 } } ,
      syn {
        "man" } ,
      orgname {
        name
          binomial {
            genus "Homo" ,
            species "sapiens" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini;
 Hominidae; Homo" ,
        gcode 1 ,
        mgcode 2 ,
        div "PRI" } } ,
    subtype {
      {
        subtype chromosome ,
        name "17" } } } ,
  gene {
    locus "AANAT" ,
    desc "arylalkylamine N-acetyltransferase" ,
    maploc "17q25" ,
    db {
      {
        db "MIM" ,
        tag
          id 600950 } } ,
    syn {
      "SNAT" ,
      "AA-NAT" } ,
    locus-tag "HGNC:19" } ,
  prot {
    name {
      "arylalkylamine N-acetyltransferase" ,
      "serotonin N-acetyltransferase" } } ,
  summary "Arylalkylamine N-acetyltransferase belongs to the superfamily of
 acetyltransferases. It is the penultimate enzyme in melatonin synthesis and
 controls the night/day rhythm in melatonin production in the vertebrate
 pineal gland. Melatonin is essential for seasonal reproduction, modulates the
 function of the circadian clock in the suprachiasmatic nucleus, and
 influences activity and sleep. This enzyme is rapidly inactivated when
 animals are exposed to light at night. This protein is 80% identical to sheep
 and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a
 multifactorial genetic diseases such as altered behavior in sleep/wake cycle." ,
  location {
    {
      display-str "17q25" ,
      method
        map-type cyto } } ,
  gene-source {
    src "LocusLink" ,
    src-int 15 ,
    src-str2 "15" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000017" ,
      version 9 ,
      seqs {
        int {
          from 71975245 ,
          to 71977793 ,
          strand plus ,
          id
            gi 51511734 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001088" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 71975245 ,
                to 71975403 ,
                strand plus ,
                id
                  gi 51511734 } ,
              int {
                from 71976348 ,
                to 71976585 ,
                strand plus ,
                id
                  gi 51511734 } ,
              int {
                from 71976849 ,
                to 71977003 ,
                strand plus ,
                id
                  gi 51511734 } ,
              int {
                from 71977341 ,
                to 71977793 ,
                strand plus ,
                id
                  gi 51511734 } } } ,
          seqs {
            whole
              gi 4501844 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001079" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 71976423 ,
                    to 71976585 ,
                    strand plus ,
                    id
                      gi 51511734 } ,
                  {
                    from 71976849 ,
                    to 71977003 ,
                    strand plus ,
                    id
                      gi 51511734 } ,
                  {
                    from 71977341 ,
                    to 71977646 ,
                    strand plus ,
                    id
                      gi 51511734 } } } ,
              seqs {
                whole
                  gi 4501845 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.87" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.87" } } } } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_010641" ,
      version 15 ,
      seqs {
        int {
          from 8389922 ,
          to 8392470 ,
          strand plus ,
          id
            gi 51474120 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_001088" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 8389922 ,
                to 8390080 ,
                strand plus ,
                id
                  gi 51474120 } ,
              int {
                from 8391025 ,
                to 8391262 ,
                strand plus ,
                id
                  gi 51474120 } ,
              int {
                from 8391526 ,
                to 8391680 ,
                strand plus ,
                id
                  gi 51474120 } ,
              int {
                from 8392018 ,
                to 8392470 ,
                strand plus ,
                id
                  gi 51474120 } } } ,
          seqs {
            whole
              gi 4501844 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_001079" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 8391100 ,
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                    strand plus ,
                    id
                      gi 51474120 } ,
                  {
                    from 8391526 ,
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                    strand plus ,
                    id
                      gi 51474120 } ,
                  {
                    from 8392018 ,
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                    strand plus ,
                    id
                      gi 51474120 } } } ,
              seqs {
                whole
                  gi 4501845 } ,
              comment {
                {
                  type property ,
                  label "EC" ,
                  text "2.3.1.87" ,
                  version 0 ,
                  xtra-properties {
                    {
                      tag "EC" ,
                      value "2.3.1.87" } } } } } } } } } ,
    {
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        int {
          from 11539555 ,
          to 11542103 ,
          strand plus ,
          id
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      products {
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                  {
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                  gi 4501845 } ,
              comment {
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      type comment ,
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      source {
        {
          anchor "HUGO Gene Nomenclature Committee" } } ,
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          type property ,
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          version 0 } ,
        {
          type property ,
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          version 0 } } } ,
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      type comment ,
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        {
          pre-text "Provided by" ,
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      comment {
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                  src {
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                    tag
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            {
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                  src {
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                    tag
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        {
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            {
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                  src {
                    db "GO" ,
                    tag
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                  anchor "circadian rhythm" ,
                  post-text "evidence: TAS" } } } } } } } } ,
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      type comment ,
      heading "Mouse, Rat" ,
      version 0 ,
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        {
          src {
            db "HomoloGene" ,
            tag
              id 31013 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=9606&chr=17&
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rg/human-chr17&query=e%3A15[id]+AND+gene[obj_type]&QSTR=aanat&cmd=focus&fill=1
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      source {
        {
          src {
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            tag
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    {
      type comment ,
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      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
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        pmid 15332344 ,
        pmid 12736803 ,
        pmid 12552951 ,
        pmid 12477932 ,
        pmid 12039872 ,
        pmid 11934439 ,
        pmid 11427721 ,
        pmid 11336675 ,
        pmid 11313340 ,
        pmid 9238858 ,
        pmid 8661026 ,
        pmid 7502081 ,
        pmid 2181999 } } ,
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          products {
            {
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                  anchor "NP_001079" ,
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              comment {
                {
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                      comment {
                        {
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            {
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              seqs {
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                  src {
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      type comment ,
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          type comment ,
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              tag "UNIGENE" ,
              value "Hs.431417" } } ,
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              src {
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          type comment ,
          text "MIM" ,
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            {
              src {
                db "MIM" ,
                tag
                  str "600950" } ,
              anchor "600950" } } } ,
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          type comment ,
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          type comment ,
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              src {
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          type comment ,
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                tag
                  str "" } ,
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              src {
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                  str "" } ,
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        {
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              src {
                db "KEGG" ,
                tag
                  str "" } ,
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    {
      type comment ,
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          type comment ,
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              src {
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              anchor "00380" ,
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    {
      type generif ,
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 arylalkylamine-N-acetyl-transferase (AA-NAT) may be an important determinant
 of the late/short sleep pattern." ,
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      refs {
        pmid 15332344 } ,
      create-date
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    {
      type generif ,
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 single nucleotide polymorphism (alanine 129--> threonine) at between patients
 with DSPS & controls.  AA-NAT could be a susceptibility gene for DSPS." ,
      version 0 ,
      refs {
        pmid 12736803 } ,
      create-date
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      update-date
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Entrezgene ::= {
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 Sciurognathi; Muridae; Murinae; Mus" ,
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    {
      type genomic ,
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      db "LocusID" ,
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      {
        db "GeneID" ,
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    update-date
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        minute 54 ,
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    genome genomic ,
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          db "taxon" ,
          tag
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
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    extra-terms FALSE } ,
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    {
      type genomic ,
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    {
      type property ,
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    {
      db "LocusID" ,
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    {
      tag "PROP" ,
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Entrezgene ::= {
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        year 2003 ,
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    update-date
      std {
        year 2005 ,
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    genome genomic ,
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          db "taxon" ,
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 Sciurognathi; Muridae; Murinae; Mus" ,
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    src "LocusLink" ,
    src-int 11287 ,
    src-str2 "11287" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000072" ,
      version 1 ,
      seqs {
        int {
          from 129138521 ,
          to 129181660 ,
          strand minus ,
          id
            gi 51863714 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007376" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 129138521 ,
                to 129138673 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129139811 ,
                to 129139852 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129140505 ,
                to 129140607 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129141065 ,
                to 129141133 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129141840 ,
                to 129141930 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129142350 ,
                to 129142480 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129142828 ,
                to 129143046 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129143853 ,
                to 129144094 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129144629 ,
                to 129144806 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129144966 ,
                to 129145040 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129145470 ,
                to 129145626 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129146112 ,
                to 129146202 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129146443 ,
                to 129146619 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129147104 ,
                to 129147187 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129149375 ,
                to 129149426 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129149655 ,
                to 129149776 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129150140 ,
                to 129150266 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129150847 ,
                to 129151075 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129151526 ,
                to 129151700 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129153906 ,
                to 129153993 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129157123 ,
                to 129157287 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129158420 ,
                to 129158569 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129161683 ,
                to 129161825 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129165292 ,
                to 129165355 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129167103 ,
                to 129167330 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129168683 ,
                to 129168844 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129171020 ,
                to 129171129 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129171763 ,
                to 129171877 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129174339 ,
                to 129174462 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129176048 ,
                to 129176132 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129176963 ,
                to 129177131 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129177687 ,
                to 129177707 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129178724 ,
                to 129178776 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129178917 ,
                to 129179070 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129180062 ,
                to 129180245 ,
                strand minus ,
                id
                  gi 51863714 } ,
              int {
                from 129181526 ,
                to 129181660 ,
                strand minus ,
                id
                  gi 51863714 } } } ,
          seqs {
            whole
              gi 6680607 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031402" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 129138651 ,
                    to 129138673 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129139811 ,
                    to 129139852 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129140505 ,
                    to 129140607 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129141065 ,
                    to 129141133 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129141840 ,
                    to 129141930 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129142350 ,
                    to 129142480 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129142828 ,
                    to 129143046 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129143853 ,
                    to 129144094 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129144629 ,
                    to 129144806 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129144966 ,
                    to 129145040 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129145470 ,
                    to 129145626 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129146112 ,
                    to 129146202 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129146443 ,
                    to 129146619 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129147104 ,
                    to 129147187 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129149375 ,
                    to 129149426 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129149655 ,
                    to 129149776 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129150140 ,
                    to 129150266 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129150847 ,
                    to 129151075 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129151526 ,
                    to 129151700 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129153906 ,
                    to 129153993 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129157123 ,
                    to 129157287 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129158420 ,
                    to 129158569 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129161683 ,
                    to 129161825 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129165292 ,
                    to 129165355 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129167103 ,
                    to 129167330 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129168683 ,
                    to 129168844 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129171020 ,
                    to 129171129 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129171763 ,
                    to 129171877 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129174339 ,
                    to 129174462 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129176048 ,
                    to 129176132 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129176963 ,
                    to 129177131 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129177687 ,
                    to 129177707 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129178724 ,
                    to 129178776 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129178917 ,
                    to 129179070 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129180062 ,
                    to 129180245 ,
                    strand minus ,
                    id
                      gi 51863714 } ,
                  {
                    from 129181526 ,
                    to 129181611 ,
                    strand minus ,
                    id
                      gi 51863714 } } } ,
              seqs {
                whole
                  gi 6680608 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_039356" ,
      version 3 ,
      seqs {
        int {
          from 3999237 ,
          to 4042376 ,
          strand minus ,
          id
            gi 51712708 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007376" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 3999237 ,
                to 3999389 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4000527 ,
                to 4000568 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4001221 ,
                to 4001323 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4001781 ,
                to 4001849 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4002556 ,
                to 4002646 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4003066 ,
                to 4003196 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4003544 ,
                to 4003762 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4004569 ,
                to 4004810 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4005345 ,
                to 4005522 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4005682 ,
                to 4005756 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4006186 ,
                to 4006342 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4006828 ,
                to 4006918 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4007159 ,
                to 4007335 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4007820 ,
                to 4007903 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4010091 ,
                to 4010142 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4010371 ,
                to 4010492 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4010856 ,
                to 4010982 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4011563 ,
                to 4011791 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4012242 ,
                to 4012416 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4014622 ,
                to 4014709 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4017839 ,
                to 4018003 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4019136 ,
                to 4019285 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4022399 ,
                to 4022541 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4026008 ,
                to 4026071 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4027819 ,
                to 4028046 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4029399 ,
                to 4029560 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4031736 ,
                to 4031845 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4032479 ,
                to 4032593 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4035055 ,
                to 4035178 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4036764 ,
                to 4036848 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4037679 ,
                to 4037847 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4038403 ,
                to 4038423 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4039440 ,
                to 4039492 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4039633 ,
                to 4039786 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4040778 ,
                to 4040961 ,
                strand minus ,
                id
                  gi 51712708 } ,
              int {
                from 4042242 ,
                to 4042376 ,
                strand minus ,
                id
                  gi 51712708 } } } ,
          seqs {
            whole
              gi 6680607 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031402" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 3999367 ,
                    to 3999389 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4000527 ,
                    to 4000568 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4001221 ,
                    to 4001323 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4001781 ,
                    to 4001849 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4002556 ,
                    to 4002646 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4003066 ,
                    to 4003196 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4003544 ,
                    to 4003762 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4004569 ,
                    to 4004810 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4005345 ,
                    to 4005522 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4005682 ,
                    to 4005756 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4006186 ,
                    to 4006342 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4006828 ,
                    to 4006918 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4007159 ,
                    to 4007335 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4007820 ,
                    to 4007903 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4010091 ,
                    to 4010142 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4010371 ,
                    to 4010492 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4010856 ,
                    to 4010982 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4011563 ,
                    to 4011791 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4012242 ,
                    to 4012416 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4014622 ,
                    to 4014709 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4017839 ,
                    to 4018003 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4019136 ,
                    to 4019285 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4022399 ,
                    to 4022541 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4026008 ,
                    to 4026071 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4027819 ,
                    to 4028046 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4029399 ,
                    to 4029560 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4031736 ,
                    to 4031845 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4032479 ,
                    to 4032593 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4035055 ,
                    to 4035178 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4036764 ,
                    to 4036848 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4037679 ,
                    to 4037847 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4038403 ,
                    to 4038423 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4039440 ,
                    to 4039492 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4039633 ,
                    to 4039786 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4040778 ,
                    to 4040961 ,
                    strand minus ,
                    id
                      gi 51712708 } ,
                  {
                    from 4042242 ,
                    to 4042327 ,
                    strand minus ,
                    id
                      gi 51712708 } } } ,
              seqs {
                whole
                  gi 6680608 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "Mouse Genome Informatics" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "Pzp" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "pregnancy zone protein" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "MGI" ,
          url "http://www.informatics.jax.org/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 5559967 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4866 } ,
                  anchor "endopeptidase inhibitor activity" ,
                  post-text "evidence: IDA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4867 } ,
                  anchor "serine-type endopeptidase inhibitor activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 17114 } ,
                  anchor "wide-spectrum protease inhibitor activity" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 5559967 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5576 } ,
                  anchor "extracellular region" ,
                  post-text "evidence: TAS" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12466851 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5615 } ,
                  anchor "extracellular space" ,
                  post-text "evidence: TAS" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 56378 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=6&
MAPS=genes-r-org/rat-chr/mouse%3A6,genes-r-org/mouse-chr6&query=e%3A11287[id]+
AND+gene[obj_type]&QSTR=pzp&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "MGI" ,
            tag
              id 87854 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "PROVISIONAL" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 12477932 ,
        pmid 12466851 ,
        pmid 7528166 ,
        pmid 5559967 ,
        pmid 1280217 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 140992 } ,
              anchor "A2m" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "D6Uwa7" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "MGI:893149" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "Pzp" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 179416 } ,
              anchor "AI838740" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "659717" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 179477 } ,
              anchor "AI893533" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "681710" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_007376" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 6680607 } ,
              anchor "NM_007376" } } ,
          seqs {
            whole
              gi 6680607 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_031402" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 6680608 } ,
                  anchor "NP_031402" ,
                  post-text "pregnancy zone protein" } } ,
              seqs {
                whole
                  gi 6680608 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 6680608 } ,
                      pre-text "(2)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5952 } ,
                          anchor "pfam00207: A2M; Alpha-2-macroglobulin family" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 738 - 1482  Blast Score: 1820" ,
                          version 0 } } } ,
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 25832 } ,
                          anchor "pfam01835: A2M_N; Alpha-2-macroglobulin
 family N-terminal region" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 22 - 622  Blast Score: 1231" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "M93264" } ,
                  anchor "M93264" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "U06977" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 463883 } ,
              anchor "U06977" } } ,
          seqs {
            whole
              gi 463883 } ,
          products {
            {
              type peptide ,
              accession "AAA87890" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 463884 } ,
                  anchor "AAA87890" } } ,
              seqs {
                whole
                  gi 463884 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC057983" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 34785995 } ,
              anchor "BC057983" } } ,
          seqs {
            whole
              gi 34785995 } ,
          products {
            {
              type peptide ,
              accession "AAH57983" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 34785996 } ,
                  anchor "AAH57983" } } ,
              seqs {
                whole
                  gi 34785996 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "FVB/N" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "M93264" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 199085 } ,
              anchor "M93264" } } ,
          seqs {
            whole
              gi 199085 } ,
          products {
            {
              type peptide ,
              accession "AAA39508" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 199086 } ,
                  anchor "AAA39508" } } ,
              seqs {
                whole
                  gi 199086 } } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "Q61838" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 2492496 } ,
                  anchor "Q61838" } } ,
              seqs {
                whole
                  gi 2492496 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "11287" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont
ig=NT_039356.3&gene=Pzp&lid=11287&from=3999238&to=4042377" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "11287" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10
090&contig=NT_039356.3&gene=Pzp&lid=11287" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Mm.260144" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Mm.260144" } ,
              anchor "Mm.260144" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=26
0144" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "11287" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
11287[loc]&TAXID=10090" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGI" ,
                tag
                  id 87854 } ,
              anchor "MGI" ,
              url "http://www.informatics.jax.org/searches/accession_report.cg
i?id=MGI:87854" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC057
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        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position=
BC057983" } } } ,
        {
          type comment ,
          text "Gene Expression Database (GXD) at MGI" ,
          version 0 ,
          source {
            {
              src {
                db "Gene Expression Database (GXD) at MGI" ,
                tag
                  str "MGI:87854" } ,
              anchor "MGI:87854" ,
              url "http://www.informatics.jax.org/searches/expression_report.c
gi?id=MGI:87854" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGC" ,
                tag
                  str "BC057983" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Mm&LIST=BC057983" } } } } } ,
    {
      type comment ,
      heading "Alleles" ,
      version 0 ,
      comment {
        {
          type comment ,
          text "The following allele types are documented at Mouse Genome
 Informatics" ,
          version 0 ,
          source {
            {
              anchor "(MGI)" ,
              url "http://www.informatics.jax.org/searches/allele_report.cgi?m
arkerID=MGI:87854" } } } ,
        {
          type comment ,
          heading "Targeted (knock-out) (1)" ,
          version 0 ,
          refs {
            pmid 7544347 } } } } } ,
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    {
      db "LocusID" ,
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    {
      db "MGI" ,
      tag
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  xtra-index-terms {
    "LOC11287" } }
Entrezgene ::= {
  track-info {
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        db "LocusID" ,
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      {
        db "GeneID" ,
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      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
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    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 54 ,
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  type unknown ,
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    genome genomic ,
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          db "taxon" ,
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
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     } ,
  gene-source {
    src "LocusLink" ,
    src-int 11288 ,
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    locus-display FALSE ,
    extra-terms FALSE } ,
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    {
      type genomic ,
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    {
      type property ,
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      std {
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    locus-display FALSE ,
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    {
      type genomic ,
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    {
      db "LocusID" ,
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    genome genomic ,
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      taxname "Mus musculus" ,
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          db "taxon" ,
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
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  gene-source {
    src "LocusLink" ,
    src-int 11293 ,
    src-str2 "11293" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
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  properties {
    {
      type property ,
      label "Property" ,
      text "phenotype only" ,
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      db "LocusID" ,
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  xtra-index-terms {
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  xtra-properties {
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      tag "PROP" ,
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Entrezgene ::= {
  track-info {
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      {
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      {
        db "GeneID" ,
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          id 109413 } } ,
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      std {
        year 2003 ,
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    update-date
      std {
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        minute 54 ,
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  type unknown ,
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    genome genomic ,
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      taxname "Mus musculus" ,
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          db "taxon" ,
          tag
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
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        mgcode 2 ,
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  gene {
     } ,
  gene-source {
    src "LocusLink" ,
    src-int 11294 ,
    src-str2 "11294" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  properties {
    {
      type property ,
      label "Property" ,
      text "phenotype only" ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
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  xtra-index-terms {
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  xtra-properties {
    {
      tag "PROP" ,
      value "phenotype only" } } }
Entrezgene ::= {
  track-info {
    geneid 11295 ,
    status secondary ,
    current-id {
      {
        db "LocusID" ,
        tag
          id 109414 } ,
      {
        db "GeneID" ,
        tag
          id 109414 } } ,
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      std {
        year 2003 ,
        month 8 ,
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        minute 39 ,
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    update-date
      std {
        year 2005 ,
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        hour 12 ,
        minute 54 ,
        second 0 } } ,
  type unknown ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Mus musculus" ,
      common "house mouse" ,
      db {
        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
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            species "musculus" } ,
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
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        mgcode 2 ,
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  gene {
     } ,
  gene-source {
    src "LocusLink" ,
    src-int 11295 ,
    src-str2 "11295" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  properties {
    {
      type property ,
      label "Property" ,
      text "phenotype only" ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
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  xtra-index-terms {
    "LOC109414" } ,
  xtra-properties {
    {
      tag "PROP" ,
      value "phenotype only" } } }
Entrezgene ::= {
  track-info {
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    status secondary ,
    current-id {
      {
        db "LocusID" ,
        tag
          id 104236 } ,
      {
        db "GeneID" ,
        tag
          id 104236 } } ,
    create-date
      std {
        year 2003 ,
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    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 54 ,
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    genome genomic ,
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          db "taxon" ,
          tag
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        name
          binomial {
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
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        mgcode 2 ,
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  gene {
     } ,
  gene-source {
    src "LocusLink" ,
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    src-str2 "11296" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
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  xtra-index-terms {
    "LOC104236" } }
Entrezgene ::= {
  track-info {
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    status secondary ,
    current-id {
      {
        db "LocusID" ,
        tag
          id 227290 } ,
      {
        db "GeneID" ,
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          id 227290 } } ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
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    update-date
      std {
        year 2005 ,
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        day 17 ,
        hour 12 ,
        minute 54 ,
        second 0 } } ,
  type protein-coding ,
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    genome genomic ,
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    org {
      taxname "Mus musculus" ,
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      db {
        {
          db "taxon" ,
          tag
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      orgname {
        name
          binomial {
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
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  gene {
     } ,
  gene-source {
    src "LocusLink" ,
    src-int 11297 ,
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    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11297 } } ,
  xtra-index-terms {
    "LOC227290" } }
Entrezgene ::= {
  track-info {
    geneid 11298 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 3 ,
        day 16 ,
        hour 16 ,
        minute 48 ,
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  type protein-coding ,
  source {
    genome genomic ,
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      taxname "Mus musculus" ,
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      db {
        {
          db "taxon" ,
          tag
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      syn {
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      orgname {
        name
          binomial {
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            species "musculus" } ,
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
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        mgcode 2 ,
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      {
        subtype chromosome ,
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      "Nat4" ,
      "SNAT" ,
      "Nat-2" } ,
    locus-tag "MGI:1328365" } ,
  prot {
    name {
      "arylalkylamine N-acetyltransferase" } } ,
  location {
    {
      display-str "11 E2" ,
      method
        map-type cyto } ,
    {
      display-str "11 70.0 cM" ,
      method
        map-type cM } } ,
  gene-source {
    src "LocusLink" ,
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    src-str2 "11298" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000077" ,
      version 1 ,
      seqs {
        int {
          from 116264815 ,
          to 116268672 ,
          strand plus ,
          id
            gi 51868608 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_009591" ,
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          genomic-coords {
            mix {
              int {
                from 116264815 ,
                to 116264902 ,
                strand plus ,
                id
                  gi 51868608 } ,
              int {
                from 116266704 ,
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                strand plus ,
                id
                  gi 51868608 } ,
              int {
                from 116267254 ,
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                strand plus ,
                id
                  gi 51868608 } ,
              int {
                from 116267917 ,
                to 116268672 ,
                strand plus ,
                id
                  gi 51868608 } } } ,
          seqs {
            whole
              gi 6752937 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_033721" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 116266765 ,
                    to 116266921 ,
                    strand plus ,
                    id
                      gi 51868608 } ,
                  {
                    from 116267254 ,
                    to 116267408 ,
                    strand plus ,
                    id
                      gi 51868608 } ,
                  {
                    from 116267917 ,
                    to 116268222 ,
                    strand plus ,
                    id
                      gi 51868608 } } } ,
              seqs {
                whole
                  gi 6752938 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_039521" ,
      version 3 ,
      seqs {
        int {
          from 27994169 ,
          to 27998026 ,
          strand plus ,
          id
            gi 51766637 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_009591" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 27994169 ,
                to 27994256 ,
                strand plus ,
                id
                  gi 51766637 } ,
              int {
                from 27996058 ,
                to 27996275 ,
                strand plus ,
                id
                  gi 51766637 } ,
              int {
                from 27996608 ,
                to 27996762 ,
                strand plus ,
                id
                  gi 51766637 } ,
              int {
                from 27997271 ,
                to 27998026 ,
                strand plus ,
                id
                  gi 51766637 } } } ,
          seqs {
            whole
              gi 6752937 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_033721" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 27996119 ,
                    to 27996275 ,
                    strand plus ,
                    id
                      gi 51766637 } ,
                  {
                    from 27996608 ,
                    to 27996762 ,
                    strand plus ,
                    id
                      gi 51766637 } ,
                  {
                    from 27997271 ,
                    to 27997576 ,
                    strand plus ,
                    id
                      gi 51766637 } } } ,
              seqs {
                whole
                  gi 6752938 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "Mouse Genome Informatics" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "Aanat" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "arylalkylamine N-acetyltransferase" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "MGI" ,
          url "http://www.informatics.jax.org/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8080 } ,
                  anchor "N-acetyltransferase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8415 } ,
                  anchor "acyltransferase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4060 } ,
                  anchor "arylamine N-acetyltransferase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16740 } ,
                  anchor "transferase activity" ,
                  post-text "evidence: IEA" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Human, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 31013 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=11
&MAPS=genes-r-org/human-chr/mouse%3A11,genes-r-org/rat-chr/mouse%3A11,genes-r-
org/mouse-chr11&query=e%3A11298[id]+AND+gene[obj_type]&QSTR=aanat&cmd=focus&fi
ll=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "MGI" ,
            tag
              id 1328365 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "PROVISIONAL" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 12138020 ,
        pmid 9838107 ,
        pmid 9708862 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 126289 } ,
              anchor "D11Mit102" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "MGI:707739" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "MPC786" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_009591" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 6752937 } ,
              anchor "NM_009591" } } ,
          seqs {
            whole
              gi 6752937 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_033721" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 6752938 } ,
                  anchor "NP_033721" ,
                  post-text "arylalkylamine N-acetyltransferase" } } ,
              seqs {
                whole
                  gi 6752938 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 6752938 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 25558 } ,
                          anchor "pfam00583: Acetyltransf_1; Acetyltransferase
 (GNAT) family" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 80 - 172  Blast Score: 118" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "AF004108" } ,
                  anchor "AF004108" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "U83462" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 4159794 } ,
              anchor "U83462" } } ,
          seqs {
            whole
              gi 4159794 } ,
          products {
            {
              type peptide ,
              accession "AAD08637" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 4099097 } ,
                  anchor "AAD08637" } } ,
              seqs {
                whole
                  gi 4099097 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "129/Sv" ,
              version 0 } } } ,
        {
          type mRNA ,
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          accession "AB013358" ,
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            {
              src {
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            whole
              gi 3298499 } ,
          products {
            {
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                {
                  src {
                    db "Protein" ,
                    tag
                      id 3298500 } ,
                  anchor "BAA31526" } } ,
              seqs {
                whole
                  gi 3298500 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "BALB/c" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AF004108" ,
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          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 4159890 } ,
              anchor "AF004108" } } ,
          seqs {
            whole
              gi 4159890 } ,
          products {
            {
              type peptide ,
              accession "AAD09408" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 4159891 } ,
                  anchor "AAD09408" } } ,
              seqs {
                whole
                  gi 4159891 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C3H/He" ,
              version 0 } } } ,
        {
          type mRNA ,
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          accession "AF004109" ,
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            {
              src {
                db "Nucleotide" ,
                tag
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          seqs {
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              gi 4159892 } ,
          products {
            {
              type peptide ,
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              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
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              seqs {
                whole
                  gi 4159893 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C3H/He" ,
              version 0 } } } ,
        {
          type mRNA ,
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          accession "AF004110" ,
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          source {
            {
              src {
                db "Nucleotide" ,
                tag
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              anchor "AF004110" } } ,
          seqs {
            whole
              gi 4159894 } ,
          products {
            {
              type peptide ,
              accession "AAD09410" ,
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              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 4159895 } ,
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              seqs {
                whole
                  gi 4159895 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6" ,
              version 0 } } } ,
        {
          type mRNA ,
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            {
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                db "Nucleotide" ,
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              gi 4159896 } ,
          products {
            {
              type peptide ,
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                {
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                  gi 4159897 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6" ,
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        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "O88816" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 11387071 } ,
                  anchor "O88816" } } ,
              seqs {
                whole
                  gi 11387071 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "11298" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont
ig=NT_039521.3&gene=Aanat&lid=11298&from=27994170&to=27998027" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "11298" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10
090&contig=NT_039521.3&gene=Aanat&lid=11298" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Mm.42233" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Mm.42233" } ,
              anchor "Mm.42233" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=42
233" } } } ,
        {
          type comment ,
          version 0 ,
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            {
              src {
                db "HomoloGene" ,
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                  str "11298" } ,
              anchor "HomoloGene" ,
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11298[loc]&TAXID=10090" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGI" ,
                tag
                  id 1328365 } ,
              anchor "MGI" ,
              url "http://www.informatics.jax.org/searches/accession_report.cg
i?id=MGI:1328365" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Mus_musculus/contigview?geneid=AF004
110" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position=
AF004110" } } } } } ,
    {
      type generif ,
      text "AANAT expression and synthesis of N-acetylserotonin/melatonin
 could play a role in addictive properties of cocaine" ,
      version 0 ,
      refs {
        pmid 12138020 } ,
      create-date
        str "Aug 19 2002 12:00AM" ,
      update-date
        str "Aug 28 2002  6:19PM" } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11298 } ,
    {
      db "MGI" ,
      tag
        id 1328365 } } ,
  xtra-index-terms {
    "LOC11298" } }
Entrezgene ::= {
  track-info {
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      {
        db "LocusID" ,
        tag
          id 20249 } ,
      {
        db "GeneID" ,
        tag
          id 20249 } } ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 54 ,
        second 0 } } ,
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    genome genomic ,
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      taxname "Mus musculus" ,
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        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
            genus "Mus" ,
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
        gcode 1 ,
        mgcode 2 ,
        div "ROD" } } } ,
  gene {
     } ,
  gene-source {
    src "LocusLink" ,
    src-int 11299 ,
    src-str2 "11299" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  properties {
    {
      type property ,
      label "Property" ,
      text "phenotype only" ,
      version 0 } } ,
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    {
      db "LocusID" ,
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  xtra-index-terms {
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  xtra-properties {
    {
      tag "PROP" ,
      value "phenotype only" } } }
Entrezgene ::= {
  track-info {
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      {
        db "GeneID" ,
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          id 112133 } } ,
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      std {
        year 2003 ,
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        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
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        day 17 ,
        hour 12 ,
        minute 54 ,
        second 0 } } ,
  type unknown ,
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    genome genomic ,
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      taxname "Mus musculus" ,
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        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
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            species "musculus" } ,
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 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
        gcode 1 ,
        mgcode 2 ,
        div "ROD" } } } ,
  gene {
     } ,
  gene-source {
    src "LocusLink" ,
    src-int 11300 ,
    src-str2 "11300" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  properties {
    {
      type property ,
      label "Property" ,
      text "phenotype only" ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11300 } } ,
  xtra-index-terms {
    "LOC112133" } ,
  xtra-properties {
    {
      tag "PROP" ,
      value "phenotype only" } } }
Entrezgene ::= {
  track-info {
    geneid 11301 ,
    status secondary ,
    current-id {
      {
        db "LocusID" ,
        tag
          id 20700 } ,
      {
        db "GeneID" ,
        tag
          id 20700 } } ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 3 ,
        day 9 ,
        hour 17 ,
        minute 35 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Mus musculus" ,
      common "house mouse" ,
      db {
        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
            genus "Mus" ,
            species "musculus" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
        gcode 1 ,
        mgcode 2 ,
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  gene {
     } ,
  gene-source {
    src "LocusLink" ,
    src-int 11301 ,
    src-str2 "11301" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11301 } } ,
  xtra-index-terms {
    "LOC20700" } }
Entrezgene ::= {
  track-info {
    geneid 11302 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 3 ,
        day 26 ,
        hour 10 ,
        minute 32 ,
        second 0 } } ,
  type protein-coding ,
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    genome genomic ,
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    org {
      taxname "Mus musculus" ,
      common "house mouse" ,
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        {
          db "taxon" ,
          tag
            id 10090 } } ,
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        "mouse" } ,
      orgname {
        name
          binomial {
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            species "musculus" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
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        mgcode 2 ,
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      {
        subtype chromosome ,
        name "11" } } } ,
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    maploc "11 E2" ,
    syn {
      "AATYK" ,
      "mKIAA0641" } ,
    locus-tag "MGI:1197518" } ,
  prot {
    name {
      "apoptosis-associated tyrosine kinase" } } ,
  location {
    {
      display-str "11 E2" ,
      method
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  gene-source {
    src "LocusLink" ,
    src-int 11302 ,
    src-str2 "11302" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000077" ,
      version 1 ,
      seqs {
        int {
          from 119678449 ,
          to 119692677 ,
          strand minus ,
          id
            gi 51868608 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007377" ,
          version 1 ,
          genomic-coords {
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              int {
                from 119678449 ,
                to 119679572 ,
                strand minus ,
                id
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              int {
                from 119680403 ,
                to 119680603 ,
                strand minus ,
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                  gi 51868608 } ,
              int {
                from 119680735 ,
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                strand minus ,
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                  gi 51868608 } ,
              int {
                from 119680962 ,
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                strand minus ,
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                  gi 51868608 } ,
              int {
                from 119683851 ,
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                strand minus ,
                id
                  gi 51868608 } ,
              int {
                from 119684576 ,
                to 119684697 ,
                strand minus ,
                id
                  gi 51868608 } ,
              int {
                from 119684778 ,
                to 119684862 ,
                strand minus ,
                id
                  gi 51868608 } ,
              int {
                from 119686587 ,
                to 119686720 ,
                strand minus ,
                id
                  gi 51868608 } ,
              int {
                from 119687234 ,
                to 119687321 ,
                strand minus ,
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                  gi 51868608 } ,
              int {
                from 119687441 ,
                to 119687559 ,
                strand minus ,
                id
                  gi 51868608 } ,
              int {
                from 119687856 ,
                to 119687935 ,
                strand minus ,
                id
                  gi 51868608 } ,
              int {
                from 119689873 ,
                to 119690020 ,
                strand minus ,
                id
                  gi 51868608 } ,
              int {
                from 119692530 ,
                to 119692677 ,
                strand minus ,
                id
                  gi 51868608 } } } ,
          seqs {
            whole
              gi 6680609 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031403" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 119679532 ,
                    to 119679572 ,
                    strand minus ,
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                      gi 51868608 } ,
                  {
                    from 119680403 ,
                    to 119680603 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119680735 ,
                    to 119680882 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119680962 ,
                    to 119683554 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119683851 ,
                    to 119684000 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119684576 ,
                    to 119684697 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119684778 ,
                    to 119684862 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119686587 ,
                    to 119686720 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119687234 ,
                    to 119687321 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119687441 ,
                    to 119687559 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119687856 ,
                    to 119687935 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119689873 ,
                    to 119690020 ,
                    strand minus ,
                    id
                      gi 51868608 } ,
                  {
                    from 119692530 ,
                    to 119692574 ,
                    strand minus ,
                    id
                      gi 51868608 } } } ,
              seqs {
                whole
                  gi 6680610 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_039521" ,
      version 3 ,
      seqs {
        int {
          from 31407803 ,
          to 31422031 ,
          strand minus ,
          id
            gi 51766637 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007377" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 31407803 ,
                to 31408926 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31409757 ,
                to 31409957 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31410089 ,
                to 31410236 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31410316 ,
                to 31412908 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31413205 ,
                to 31413354 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31413930 ,
                to 31414051 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31414132 ,
                to 31414216 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31415941 ,
                to 31416074 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31416588 ,
                to 31416675 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31416795 ,
                to 31416913 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31417210 ,
                to 31417289 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31419227 ,
                to 31419374 ,
                strand minus ,
                id
                  gi 51766637 } ,
              int {
                from 31421884 ,
                to 31422031 ,
                strand minus ,
                id
                  gi 51766637 } } } ,
          seqs {
            whole
              gi 6680609 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031403" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 31408886 ,
                    to 31408926 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31409757 ,
                    to 31409957 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31410089 ,
                    to 31410236 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31410316 ,
                    to 31412908 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31413205 ,
                    to 31413354 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31413930 ,
                    to 31414051 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31414132 ,
                    to 31414216 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31415941 ,
                    to 31416074 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31416588 ,
                    to 31416675 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31416795 ,
                    to 31416913 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31417210 ,
                    to 31417289 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31419227 ,
                    to 31419374 ,
                    strand minus ,
                    id
                      gi 51766637 } ,
                  {
                    from 31421884 ,
                    to 31421928 ,
                    strand minus ,
                    id
                      gi 51766637 } } } ,
              seqs {
                whole
                  gi 6680610 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "Mouse Genome Informatics" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "Aatk" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "apoptosis-associated tyrosine kinase" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "MGI" ,
          url "http://www.informatics.jax.org/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5524 } ,
                  anchor "ATP binding" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16301 } ,
                  anchor "kinase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12466851 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4672 } ,
                  anchor "protein kinase activity" ,
                  post-text "evidence: ISS" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12466851 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4674 } ,
                  anchor "protein serine/threonine kinase activity" ,
                  post-text "evidence: ISS" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9444961 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4713 } ,
                  anchor "protein-tyrosine kinase activity" ,
                  post-text "evidence: ISS" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16740 } ,
                  anchor "transferase activity" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9444961 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6915 } ,
                  anchor "apoptosis" ,
                  post-text "evidence: IDA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12466851 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6468 } ,
                  anchor "protein amino acid phosphorylation" ,
                  post-text "evidence: ISS" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 7223 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=11
&MAPS=genes-r-org/rat-chr/mouse%3A11,genes-r-org/mouse-chr11&query=e%3A11302[i
d]+AND+gene[obj_type]&QSTR=aatk&cmd=focus&fill=10" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "MGI" ,
            tag
              id 1197518 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "PROVISIONAL" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 12670708 ,
        pmid 12477932 ,
        pmid 12466851 ,
        pmid 11314039 ,
        pmid 11217851 ,
        pmid 11076861 ,
        pmid 11042159 ,
        pmid 10349636 ,
        pmid 9444961 } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_007377" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 52345410 } ,
              anchor "NM_007377" } } ,
          seqs {
            whole
              gi 52345410 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_031403" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 52345411 } ,
                  anchor "NP_031403" ,
                  post-text "apoptosis-associated tyrosine kinase" } } ,
              seqs {
                whole
                  gi 52345411 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 52345411 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5392 } ,
                          anchor "cd00192: TyrKc; Tyrosine kinase, catalytic
 domain" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 75 - 348  Blast Score: 588" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "BC080846" } ,
                  anchor "BC080846" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AB093253" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 39104554 } ,
              anchor "AB093253" } } ,
          seqs {
            whole
              gi 39104554 } ,
          products {
            {
              type peptide ,
              accession "BAC41437" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 39104555 } ,
                  anchor "BAC41437" } } ,
              seqs {
                whole
                  gi 39104555 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AF011908" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 2459992 } ,
              anchor "AF011908" } } ,
          seqs {
            whole
              gi 2459992 } ,
          products {
            {
              type peptide ,
              accession "AAB71837" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 2459993 } ,
                  anchor "AAB71837" } } ,
              seqs {
                whole
                  gi 2459993 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK036705" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 26331621 } ,
              anchor "AK036705" } } ,
          seqs {
            whole
              gi 26331621 } ,
          products {
            {
              type peptide ,
              accession "BAC29541" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 26331622 } ,
                  anchor "BAC29541" } } ,
              seqs {
                whole
                  gi 26331622 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK076214" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 26096668 } ,
              anchor "AK076214" } } ,
          seqs {
            whole
              gi 26096668 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AY236858" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 29824955 } ,
              anchor "AY236858" } } ,
          seqs {
            whole
              gi 29824955 } ,
          products {
            {
              type peptide ,
              accession "AAO92350" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 29824956 } ,
                  anchor "AAO92350" } } ,
              seqs {
                whole
                  gi 29824956 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AY236859" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 29824957 } ,
              anchor "AY236859" } } ,
          seqs {
            whole
              gi 29824957 } ,
          products {
            {
              type peptide ,
              accession "AAO92351" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 29824958 } ,
                  anchor "AAO92351" } } ,
              seqs {
                whole
                  gi 29824958 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "129/SvJ" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC042837" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 27769340 } ,
              anchor "BC042837" } } ,
          seqs {
            whole
              gi 27769340 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC052323" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 30410866 } ,
              anchor "BC052323" } } ,
          seqs {
            whole
              gi 30410866 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC080846" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 51593713 } ,
              anchor "BC080846" } } ,
          seqs {
            whole
              gi 51593713 } ,
          products {
            {
              type peptide ,
              accession "AAH80846" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 51593714 } ,
                  anchor "AAH80846" } } ,
              seqs {
                whole
                  gi 51593714 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "11302" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont
ig=NT_039521.3&gene=Aatk&lid=11302&from=31407804&to=31422032" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "11302" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10
090&contig=NT_039521.3&gene=Aatk&lid=11302" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Mm.6826" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Mm.6826" } ,
              anchor "Mm.6826" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=68
26" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "11302" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
11302[loc]&TAXID=10090" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGI" ,
                tag
                  id 1197518 } ,
              anchor "MGI" ,
              url "http://www.informatics.jax.org/searches/accession_report.cg
i?id=MGI:1197518" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC052
323" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position=
BC052323" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGC" ,
                tag
                  str "BC080846" } ,
              anchor "MGC" ,
              url "http://mgc.nci.nih.gov/Genes/CloneList?ORG=Mm&LIST=BC080846" } } } } } ,
    {
      type generif ,
      text "Expression of AATYK mRNA and protein increased during postnatal
 brain development. In immature granule cells, overexpression of AATYK
 promoted neurite outgrowth; a tyrosine kinase-defective mutant significantly
 inhibited it." ,
      version 0 ,
      refs {
        pmid 12670708 } ,
      create-date
        str "Jun 17 2003 12:00AM" ,
      update-date
        str "Aug  3 2003  7:06AM" } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11302 } ,
    {
      db "MGI" ,
      tag
        id 1197518 } } ,
  xtra-index-terms {
    "LOC11302" } }
Entrezgene ::= {
  track-info {
    geneid 11303 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 19 ,
        hour 12 ,
        minute 12 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Mus musculus" ,
      common "house mouse" ,
      db {
        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
            genus "Mus" ,
            species "musculus" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
        gcode 1 ,
        mgcode 2 ,
        div "ROD" } } ,
    subtype {
      {
        subtype chromosome ,
        name "4" } } } ,
  gene {
    locus "Abca1" ,
    desc "ATP-binding cassette, sub-family A (ABC1), member 1" ,
    maploc "4 23.1 cM" ,
    syn {
      "Abc1" } ,
    locus-tag "MGI:99607" } ,
  prot {
    name {
      "ATP-binding cassette 1, sub-family A, member 1" ,
      "ATP-binding cassette 1" } } ,
  summary "The membrane-associated protein encoded by this gene is a member of
 the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins
 transport various molecules across extra- and intracellular membranes. ABC
 genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD,
 OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members
 of the ABC1 subfamily comprise the only major ABC subfamily found exclusively
 in multicellular eukaryotes. In humans, this protein functions as a
 cholesterol efflux pump in the cellular lipid removal pathway. Mutations in
 the human gene have been associated with Tangier's disease and familial
 high-density lipoprotein deficiency." ,
  location {
    {
      display-str "4 A5-B3" ,
      method
        map-type cyto } ,
    {
      display-str "4 23.1 cM" ,
      method
        map-type cM } } ,
  gene-source {
    src "LocusLink" ,
    src-int 11303 ,
    src-str2 "11303" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000070" ,
      version 1 ,
      seqs {
        int {
          from 52275832 ,
          to 52404936 ,
          strand minus ,
          id
            gi 51860768 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_013454" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 52275832 ,
                to 52279127 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52280381 ,
                to 52280624 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52281306 ,
                to 52281398 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52281917 ,
                to 52282020 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52283201 ,
                to 52283335 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52283663 ,
                to 52283804 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52285763 ,
                to 52285869 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52286583 ,
                to 52286645 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52287358 ,
                to 52287478 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52287708 ,
                to 52287837 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52289159 ,
                to 52289282 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52290819 ,
                to 52290963 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52291074 ,
                to 52291189 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52294000 ,
                to 52294177 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52295333 ,
                to 52295502 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52295979 ,
                to 52296053 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52304301 ,
                to 52304406 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52305377 ,
                to 52305409 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52306531 ,
                to 52306625 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52307434 ,
                to 52307623 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52310945 ,
                to 52311043 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52312075 ,
                to 52312199 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52313731 ,
                to 52313879 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52314836 ,
                to 52314949 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52315120 ,
                to 52315168 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52316867 ,
                to 52317069 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52317942 ,
                to 52318014 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52319264 ,
                to 52319484 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52320175 ,
                to 52320312 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52320491 ,
                to 52320633 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52321935 ,
                to 52322066 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52322987 ,
                to 52323158 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52324615 ,
                to 52324728 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52325810 ,
                to 52326014 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52326966 ,
                to 52327187 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52328761 ,
                to 52328983 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52329428 ,
                to 52329604 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52330140 ,
                to 52330345 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52331037 ,
                to 52331234 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52334843 ,
                to 52334959 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52335298 ,
                to 52335437 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52337773 ,
                to 52338013 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52340629 ,
                to 52340721 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52352050 ,
                to 52352226 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52354208 ,
                to 52354329 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52372641 ,
                to 52372759 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52373765 ,
                to 52373906 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52377966 ,
                to 52378059 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52388974 ,
                to 52389139 ,
                strand minus ,
                id
                  gi 51860768 } ,
              int {
                from 52404720 ,
                to 52404936 ,
                strand minus ,
                id
                  gi 51860768 } } } ,
          seqs {
            whole
              gi 34577068 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_038482" ,
              version 2 ,
              genomic-coords {
                packed-int {
                  {
                    from 52278987 ,
                    to 52279127 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52280381 ,
                    to 52280624 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52281306 ,
                    to 52281398 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52281917 ,
                    to 52282020 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52283201 ,
                    to 52283335 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52283663 ,
                    to 52283804 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52285763 ,
                    to 52285869 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52286583 ,
                    to 52286645 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52287358 ,
                    to 52287478 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52287708 ,
                    to 52287837 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52289159 ,
                    to 52289282 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52290819 ,
                    to 52290963 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52291074 ,
                    to 52291189 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52294000 ,
                    to 52294177 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52295333 ,
                    to 52295502 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52295979 ,
                    to 52296053 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52304301 ,
                    to 52304406 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52305377 ,
                    to 52305409 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52306531 ,
                    to 52306625 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52307434 ,
                    to 52307623 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52310945 ,
                    to 52311043 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52312075 ,
                    to 52312199 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52313731 ,
                    to 52313879 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52314836 ,
                    to 52314949 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52315120 ,
                    to 52315168 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52316867 ,
                    to 52317069 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52317942 ,
                    to 52318014 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52319264 ,
                    to 52319484 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52320175 ,
                    to 52320312 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52320491 ,
                    to 52320633 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52321935 ,
                    to 52322066 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52322987 ,
                    to 52323158 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52324615 ,
                    to 52324728 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52325810 ,
                    to 52326014 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52326966 ,
                    to 52327187 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52328761 ,
                    to 52328983 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52329428 ,
                    to 52329604 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52330140 ,
                    to 52330345 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52331037 ,
                    to 52331234 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52334843 ,
                    to 52334959 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52335298 ,
                    to 52335437 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52337773 ,
                    to 52338013 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52340629 ,
                    to 52340721 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52352050 ,
                    to 52352226 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52354208 ,
                    to 52354329 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52372641 ,
                    to 52372759 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52373765 ,
                    to 52373906 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52377966 ,
                    to 52378059 ,
                    strand minus ,
                    id
                      gi 51860768 } ,
                  {
                    from 52388974 ,
                    to 52389039 ,
                    strand minus ,
                    id
                      gi 51860768 } } } ,
              seqs {
                whole
                  gi 34577069 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_039260" ,
      version 3 ,
      seqs {
        int {
          from 26554540 ,
          to 26683644 ,
          strand minus ,
          id
            gi 51709342 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_013454" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 26554540 ,
                to 26557835 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26559089 ,
                to 26559332 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26560014 ,
                to 26560106 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26560625 ,
                to 26560728 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26561909 ,
                to 26562043 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26562371 ,
                to 26562512 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26564471 ,
                to 26564577 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26565291 ,
                to 26565353 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26566066 ,
                to 26566186 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26566416 ,
                to 26566545 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26567867 ,
                to 26567990 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26569527 ,
                to 26569671 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26569782 ,
                to 26569897 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26572708 ,
                to 26572885 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26574041 ,
                to 26574210 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26574687 ,
                to 26574761 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26583009 ,
                to 26583114 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26584085 ,
                to 26584117 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26585239 ,
                to 26585333 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26586142 ,
                to 26586331 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26589653 ,
                to 26589751 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26590783 ,
                to 26590907 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26592439 ,
                to 26592587 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26593544 ,
                to 26593657 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26593828 ,
                to 26593876 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26595575 ,
                to 26595777 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26596650 ,
                to 26596722 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26597972 ,
                to 26598192 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26598883 ,
                to 26599020 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26599199 ,
                to 26599341 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26600643 ,
                to 26600774 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26601695 ,
                to 26601866 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26603323 ,
                to 26603436 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26604518 ,
                to 26604722 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26605674 ,
                to 26605895 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26607469 ,
                to 26607691 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26608136 ,
                to 26608312 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26608848 ,
                to 26609053 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26609745 ,
                to 26609942 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26613551 ,
                to 26613667 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26614006 ,
                to 26614145 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26616481 ,
                to 26616721 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26619337 ,
                to 26619429 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26630758 ,
                to 26630934 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26632916 ,
                to 26633037 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26651349 ,
                to 26651467 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26652473 ,
                to 26652614 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26656674 ,
                to 26656767 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26667682 ,
                to 26667847 ,
                strand minus ,
                id
                  gi 51709342 } ,
              int {
                from 26683428 ,
                to 26683644 ,
                strand minus ,
                id
                  gi 51709342 } } } ,
          seqs {
            whole
              gi 34577068 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_038482" ,
              version 2 ,
              genomic-coords {
                packed-int {
                  {
                    from 26557695 ,
                    to 26557835 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26559089 ,
                    to 26559332 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26560014 ,
                    to 26560106 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26560625 ,
                    to 26560728 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26561909 ,
                    to 26562043 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26562371 ,
                    to 26562512 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26564471 ,
                    to 26564577 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26565291 ,
                    to 26565353 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26566066 ,
                    to 26566186 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26566416 ,
                    to 26566545 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26567867 ,
                    to 26567990 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26569527 ,
                    to 26569671 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26569782 ,
                    to 26569897 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26572708 ,
                    to 26572885 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26574041 ,
                    to 26574210 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26574687 ,
                    to 26574761 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26583009 ,
                    to 26583114 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26584085 ,
                    to 26584117 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26585239 ,
                    to 26585333 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26586142 ,
                    to 26586331 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26589653 ,
                    to 26589751 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26590783 ,
                    to 26590907 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26592439 ,
                    to 26592587 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26593544 ,
                    to 26593657 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26593828 ,
                    to 26593876 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26595575 ,
                    to 26595777 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26596650 ,
                    to 26596722 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26597972 ,
                    to 26598192 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26598883 ,
                    to 26599020 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26599199 ,
                    to 26599341 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26600643 ,
                    to 26600774 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26601695 ,
                    to 26601866 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26603323 ,
                    to 26603436 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26604518 ,
                    to 26604722 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26605674 ,
                    to 26605895 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26607469 ,
                    to 26607691 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26608136 ,
                    to 26608312 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26608848 ,
                    to 26609053 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26609745 ,
                    to 26609942 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26613551 ,
                    to 26613667 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26614006 ,
                    to 26614145 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26616481 ,
                    to 26616721 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26619337 ,
                    to 26619429 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26630758 ,
                    to 26630934 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26632916 ,
                    to 26633037 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26651349 ,
                    to 26651467 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26652473 ,
                    to 26652614 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26656674 ,
                    to 26656767 ,
                    strand minus ,
                    id
                      gi 51709342 } ,
                  {
                    from 26667682 ,
                    to 26667747 ,
                    strand minus ,
                    id
                      gi 51709342 } } } ,
              seqs {
                whole
                  gi 34577069 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "Mouse Genome Informatics" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "Abca1" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "ATP-binding cassette, sub-family A (ABC1), member 1" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "MGI" ,
          url "http://www.informatics.jax.org/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5524 } ,
                  anchor "ATP binding" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
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                    tag
                      id 16887 } ,
                  anchor "ATPase activity" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Process" ,
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          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 11559713 } ,
              source {
                {
                  src {
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                    tag
                      id 8203 } ,
                  anchor "cholesterol metabolism" ,
                  post-text "evidence: IDA" } } } ,
            {
              type comment ,
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                    tag
                      id 30301 } ,
                  anchor "cholesterol transport" ,
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            {
              type comment ,
              version 0 ,
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                pmid 12859204 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 42158 } ,
                  anchor "lipoprotein biosynthesis" ,
                  post-text "evidence: IMP" } } } ,
            {
              type comment ,
              version 0 ,
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                pmid 10878804 } ,
              source {
                {
                  src {
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                    tag
                      id 6911 } ,
                  anchor "phagocytosis, engulfment" ,
                  post-text "evidence: IMP" } } } ,
            {
              type comment ,
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                  src {
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                    tag
                      id 45332 } ,
                  anchor "phospholipid translocation" ,
                  post-text "evidence: IMP" } } } ,
            {
              type comment ,
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                  src {
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                    tag
                      id 6810 } ,
                  anchor "transport" ,
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        {
          type comment ,
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            {
              type comment ,
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            {
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                  anchor "integral to membrane" ,
                  post-text "evidence: TAS" } } } ,
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                  anchor "integral to plasma membrane" ,
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                  src {
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                    tag
                      id 43231 } ,
                  anchor "intracellular membrane-bound organelle" ,
                  post-text "evidence: IDA" } } } } } } } } ,
  homology {
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      type comment ,
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          src {
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            tag
              id 21130 } ,
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  comments {
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          src {
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            tag
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    {
      type comment ,
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    {
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        pmid 15026428 ,
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        pmid 10349636 ,
        pmid 8889548 ,
        pmid 8088782 ,
        pmid 7774911 } } ,
    {
      type comment ,
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        {
          type comment ,
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            {
              src {
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                tag
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              anchor "X75926" ,
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              text "3512" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
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              gi 34577068 } ,
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                          type other ,
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                        {
                          type other ,
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                        {
                          type other ,
                          text "Location: 1912 - 2218  Blast Score: 360" ,
                          version 0 } } } } } } } } ,
          comment {
            {
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                      str "AK045442,BB657864,CA885568,X75926" } ,
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                {
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    {
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                      id 11611825 } ,
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                whole
                  gi 11611825 } } } ,
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              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
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              src {
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                tag
                  id 12859824 } ,
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          seqs {
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              gi 12859824 } ,
          products {
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              type peptide ,
              text "None" ,
              version 0 } } ,
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            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
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        {
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            {
              src {
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                tag
                  id 26090897 } ,
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          seqs {
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              gi 26090897 } ,
          products {
            {
              type peptide ,
              text "None" ,
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            {
              type other ,
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              text "C57BL/6J" ,
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        {
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            {
              src {
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                tag
                  id 26342297 } ,
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          seqs {
            whole
              gi 26342297 } ,
          products {
            {
              type peptide ,
              accession "BAC34811" ,
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                {
                  src {
                    db "Protein" ,
                    tag
                      id 26342298 } ,
                  anchor "BAC34811" } } ,
              seqs {
                whole
                  gi 26342298 } } } ,
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            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
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              src {
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                  id 16491690 } ,
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          seqs {
            whole
              gi 16491690 } ,
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            {
              type peptide ,
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        {
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              src {
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                  id 27337117 } ,
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              gi 27337117 } ,
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            {
              type peptide ,
              text "None" ,
              version 0 } } ,
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            {
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              text "CD-1" ,
              version 0 } } } ,
        {
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            {
              src {
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                tag
                  id 495256 } ,
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              gi 495256 } ,
          products {
            {
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                    tag
                      id 495257 } ,
                  anchor "CAA53530" } } ,
              seqs {
                whole
                  gi 495257 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "DBA/2" ,
              version 0 } } } ,
        {
          type other ,
          text "None" ,
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          products {
            {
              type peptide ,
              accession "P41233" ,
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              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 51338775 } ,
                  anchor "P41233" } } ,
              seqs {
                whole
                  gi 51338775 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
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      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "11303" } ,
              anchor "Evidence Viewer" ,
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        {
          type comment ,
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            {
              src {
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                  str "11303" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10
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        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Mm.277376" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Mm.277376" } ,
              anchor "Mm.277376" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=27
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        {
          type comment ,
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            {
              src {
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                  str "11303" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
11303[loc]&TAXID=10090" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGI" ,
                tag
                  id 99607 } ,
              anchor "MGI" ,
              url "http://www.informatics.jax.org/searches/accession_report.cg
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        {
          type comment ,
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          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Mus_musculus/contigview?geneid=X7592
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        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position=
X75926" } } } ,
        {
          type comment ,
          text "Gene Expression Database (GXD) at MGI" ,
          version 0 ,
          source {
            {
              src {
                db "Gene Expression Database (GXD) at MGI" ,
                tag
                  str "MGI:99607" } ,
              anchor "MGI:99607" ,
              url "http://www.informatics.jax.org/searches/expression_report.c
gi?id=MGI:99607" } } } ,
        {
          type comment ,
          text "Human ABC-Transporter Proteins" ,
          version 0 ,
          source {
            {
              src {
                db "Human ABC-Transporter Proteins" ,
                tag
                  str "Human ABC-Transporter Proteins" } ,
              anchor "Human ABC-Transporter Proteins" ,
              url "http://nutrigene.4t.com/humanabc.htm" } } } } } ,
    {
      type generif ,
      text "Gene deletion protects aginst cerebral malaria from Plasmodium
 berghei." ,
      version 0 ,
      refs {
        pmid 15632021 } ,
      create-date
        str "Mar  7 2005  7:07PM" ,
      update-date
        str "Mar  8 2005  3:26AM" } ,
    {
      type generif ,
      text "ABCA1-dependent cholesterol mobilization to apoA-I increased new
 cholesterol synthesis, indicating depletion of the regulatory pool of
 hepatocyte cholesterol during HDL formation" ,
      version 0 ,
      refs {
        pmid 14993246 } ,
      create-date
        str "Mar  7 2005  7:07PM" ,
      update-date
        str "Mar  8 2005 12:40AM" } ,
    {
      type generif ,
      text "a 21% decrease (P = 0.01) in fertility was observed between
 ABCA1(-/-) males compared with WT controls across their reproductive
 lifespans" ,
      version 0 ,
      refs {
        pmid 15026428 } ,
      create-date
        str "Mar  7 2005  7:07PM" ,
      update-date
        str "Mar  7 2005  9:28PM" } ,
    {
      type generif ,
      text "Verapamil increases ABCA1 expression through LXR-independent
 mechanism and thereby increases apoA-I-mediated cellular lipid release and
 production of HDL." ,
      version 0 ,
      refs {
        pmid 14726413 } ,
      create-date
        str "Jan  8 2005 10:01AM" ,
      update-date
        str "Jan  8 2005  2:49PM" } ,
    {
      type generif ,
      text "In murine macrophage cell line RAW264 cells, cAMP induced
 expression of ABCA1, release of cellular phospholipid and cholesterol by
 apoA-I, and reversible binding of apoA-I to the cell." ,
      version 0 ,
      refs {
        pmid 14729855 } ,
      create-date
        str "Dec  4 2004 10:01AM" ,
      update-date
        str "Dec  4 2004  2:26PM" } ,
    {
      type generif ,
      text "The time course and temperature dependence of ABCA1-mediated lipid
 efflux to apoA-I support a role for endocytosis in this process" ,
      version 0 ,
      refs {
        pmid 14703508 } ,
      create-date
        str "Dec  4 2004 10:01AM" ,
      update-date
        str "Dec  4 2004 11:09AM" } ,
    {
      type generif ,
      text "conclude that intact ATP binding cassette transporter A1 (ABCA1)
 function is necessary for proper maturation of dense bodies in platelets" ,
      version 0 ,
      refs {
        pmid 15163665 } ,
      create-date
        str "Oct 30 2004 10:01AM" ,
      update-date
        str "Oct 30 2004 10:58AM" } ,
    {
      type generif ,
      text "glial ABCA1 has a key role in apoE metabolism in the brain" ,
      version 0 ,
      refs {
        pmid 15269218 } ,
      create-date
        str "Oct 30 2004 10:01AM" ,
      update-date
        str "Oct 30 2004 10:43AM" } ,
    {
      type generif ,
      text "ABCA1 plays a critical role in central nervous system apoE
 metabolism" ,
      version 0 ,
      refs {
        pmid 15269217 } ,
      create-date
        str "Oct 30 2004 10:01AM" ,
      update-date
        str "Oct 30 2004 10:43AM" } ,
    {
      type generif ,
      text "PPAR alpha influences cholesterol absorption through modulating
 the ATP binding cassette transporter A1 activity in the intestine by a
 mechanism involving liver X receptor alpha" ,
      version 0 ,
      refs {
        pmid 12897186 } ,
      create-date
        str "Aug  9 2004  1:01PM" ,
      update-date
        str "Aug  9 2004  1:41PM" } ,
    {
      type generif ,
      text "When endotoxin or cytokines (tumor necrosis factor and
 interleukin-1) were incubated with J774 murine macrophages, the mRNA levels
 of ABCA1 were decreased." ,
      version 0 ,
      refs {
        pmid 12777468 } ,
      create-date
        str "Jul 12 2004 11:39AM" ,
      update-date
        str "Jul 12 2004 12:16PM" } ,
    {
      type generif ,
      text "ABCA1 is stabilized by a specific structural element possessing a
 linear array of acidic residues spanning two apoA-I amphipathic alpha-helices" ,
      version 0 ,
      refs {
        pmid 15051721 } ,
      create-date
        str "Jul 12 2004 11:39AM" ,
      update-date
        str "Jul 12 2004 11:52AM" } ,
    {
      type generif ,
      text "despite large induction of ABCA1 mRNA during differentiation,
 cholesterol efflux through the ABCA1 pathway remains limited in adipocytes
 and requires prolonged lipolysis" ,
      version 0 ,
      refs {
        pmid 12754274 } ,
      create-date
        str "Jun 23 2004  4:43PM" ,
      update-date
        str "Jun 23 2004  5:25PM" } ,
    {
      type generif ,
      text "ABCA1 turnover is modulated by alpha1-syntrophin" ,
      version 0 ,
      refs {
        pmid 14722086 } ,
      create-date
        str "Jun 14 2004  4:41PM" ,
      update-date
        str "Jun 14 2004  5:46PM" } ,
    {
      type generif ,
      text "Review. ABCA1-deficient mice are used to demonstrate the relation
 between ABCA1 expression, cellular lipid efflux, & HDL metabolism. The
 ABCA1-deficient mouse phenotype parallels that of human Tangier disease." ,
      version 0 ,
      refs {
        pmid 12615679 } ,
      create-date
        str "Jan 25 2004 12:00AM" ,
      update-date
        str "Feb 29 2004  7:03AM" } ,
    {
      type generif ,
      text "cellular ATP-binding cassette transporter A1 has a role in
 transporting cholesterol and phospholipids from cells to lipoprotein
 particles by a process involving PLTP interactions" ,
      version 0 ,
      refs {
        pmid 14559902 } ,
      create-date
        str "Jan 20 2004 12:00AM" ,
      update-date
        str "Feb 15 2004  6:35PM" } ,
    {
      type generif ,
      text "Results demonstrate that ABCA1 plays a key role in hepatic
 cholesterol efflux, inducing pathways that modulate cholesterol homeostasis
 in the liver, and establish the liver as a major source of plasma HDL-C." ,
      version 0 ,
      refs {
        pmid 12576511 } ,
      create-date
        str "Jan  5 2004 12:00AM" ,
      update-date
        str "Feb 29 2004  7:03AM" } ,
    {
      type generif ,
      text "ABCA1-mediated vesicle release involves lipid raft plasma membrane
 domains" ,
      version 0 ,
      refs {
        pmid 12928428 } ,
      create-date
        str "Nov 30 2003 12:00AM" ,
      update-date
        str "Jan  4 2004  7:03AM" } ,
    {
      type generif ,
      text "These studies indicate a direct role of retinoic acid receptor
 gamma/retinoid x receptor in induction of macrophage ABCA1." ,
      version 0 ,
      refs {
        pmid 14560020 } ,
      create-date
        str "Nov 17 2003 12:00AM" ,
      update-date
        str "Dec  7 2003  7:05AM" } ,
    {
      type generif ,
      text "As observed in knockout mice, ABCA1 is necessary for the adequate
 lipidation of apoAI, which enables the interaction with LCAT and subsequent
 maturation." ,
      version 0 ,
      refs {
        pmid 12859204 } ,
      create-date
        str "Sep 30 2003 12:00AM" ,
      update-date
        str "Oct 12 2003  7:03AM" } ,
    {
      type generif ,
      text "ABCA1 and SREBP1 are regulated by liver X receptor/corepressor
 complexes" ,
      version 0 ,
      refs {
        pmid 12897148 } ,
      create-date
        str "Aug 25 2003 12:00AM" ,
      update-date
        str "Aug 31 2003  7:04AM" } ,
    {
      type generif ,
      text "Estrogen's antiatherogenic effects may occur via ABCA1-mediated
 pathway, and circulating HDL levels may influence expression of ABCA1" ,
      version 0 ,
      refs {
        pmid 12487373 } ,
      create-date
        str "Jun  3 2003 12:00AM" ,
      update-date
        str "Jun  8 2003  7:28AM" } ,
    {
      type generif ,
      text "Hepatocyte expression of ABCA1 is central to the lipidation of
 newly synthesized apoA-I but also contributes to the lipidation of exogenous
 apoA-I." ,
      version 0 ,
      refs {
        pmid 12547832 } ,
      create-date
        str "Apr  2 2003 12:00AM" ,
      update-date
        str "May 11 2003  7:05AM" } ,
    {
      type generif ,
      text "Golgi is involved in ABCA1-mediated cholesterol efflux." ,
      version 0 ,
      refs {
        pmid 12551894 } ,
      create-date
        str "Apr  1 2003 12:00AM" ,
      update-date
        str "May 11 2003  7:05AM" } ,
    {
      type generif ,
      text "ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux
 is promoted by central helices of ApoA-I; amino acid residues 220-231 of the
 wild-type ApoA-I are required for lipid efflux and high density lipoprotein
 formation" ,
      version 0 ,
      refs {
        pmid 12488454 } ,
      create-date
        str "Mar 20 2003 12:00AM" ,
      update-date
        str "Apr 13 2003  7:04AM" } ,
    {
      type generif ,
      text "annexin I is externalized from pituitary folliculo-stellate cells
 by an ABC transporter and the ATP binding cassette transporter A1 is a likely
 candidate" ,
      version 0 ,
      refs {
        pmid 12586783 } ,
      create-date
        str "Mar 19 2003 12:00AM" ,
      update-date
        str "Mar 31 2003  6:34AM" } ,
    {
      type generif ,
      text "ATP-binding-cassette transporter A1 gene expression in macrophages
 is downregulated by statins" ,
      version 0 ,
      refs {
        pmid 15033469 } ,
      create-date
        str "Apr 26 2004 12:00AM" ,
      update-date
        str "May 23 2004  7:05AM" } ,
    {
      type generif ,
      text "ABCA1 is regulated by PEST sequence-mediated calpain proteolysis
 that appears to be reversed by apolipoprotein-mediated phospholipid efflux" ,
      version 0 ,
      refs {
        pmid 12511593 } ,
      create-date
        str "Feb  7 2003 12:00AM" ,
      update-date
        str "Mar  9 2003  7:04AM" } ,
    {
      type generif ,
      text "REVIEW: ATP-binding cassette transporter A1 and cholesterol
 trafficking" ,
      version 0 ,
      refs {
        pmid 12151852 } ,
      create-date
        str "Jan 24 2003 12:00AM" ,
      update-date
        str "Feb  2 2003  7:50AM" } ,
    {
      type generif ,
      text "mediates cholesterol efflux and is defective in free
 cholesterol-loaded macrophages; mechanism involves enhanced degradation and
 full npc1 activity." ,
      version 0 ,
      refs {
        pmid 12215451 } ,
      create-date
        str "Jan 16 2003 12:00AM" ,
      update-date
        str "Feb  9 2003  7:14AM" } ,
    {
      type generif ,
      text "induction as a result of liver X receptor agonism increases
 secreted Abeta levels" ,
      version 0 ,
      refs {
        pmid 12384498 } ,
      create-date
        str "Jan  9 2003 12:00AM" ,
      update-date
        str "Feb  2 2003  7:50AM" } ,
    {
      type generif ,
      text "Increased hepatobiliary and fecal cholesterol excretion upon
 activation of the liver X receptor is independent of ABCA1." ,
      version 0 ,
      refs {
        pmid 12105210 } ,
      create-date
        str "Nov 20 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:50AM" } ,
    {
      type generif ,
      text "A novel serine (Ser-2054) on the ABCA1 protein crucial for PKA
 phosphorylation and for regulation of ABCA1 transporter activity." ,
      version 0 ,
      refs {
        pmid 12196520 } ,
      create-date
        str "Nov 16 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:50AM" } ,
    {
      type generif ,
      text "studies establish a novel binding site for apoA-I on the
 macrophage extracellular matrix that may function together with ABCA1 in
 promoting cholesterol efflux" ,
      version 0 ,
      refs {
        pmid 12050168 } ,
      create-date
        str "Sep 27 2002 12:00AM" ,
      update-date
        str "Feb  2 2003  7:49AM" } ,
    {
      type generif ,
      text "Role as a phosphatidylserine translocase" ,
      version 0 ,
      refs {
        pmid 11893753 } ,
      create-date
        str "Jul  8 2002 12:00AM" ,
      update-date
        str "Jul 22 2002  5:59AM" } ,
    {
      type generif ,
      text "Leukocyte ABCA1 controls susceptibility to atherosclerosis and
 macrophage recruitment into tissues" ,
      version 0 ,
      refs {
        pmid 11972062 } ,
      create-date
        str "May 31 2002 12:00AM" ,
      update-date
        str "Jun 15 2002  8:10AM" } ,
    {
      type generif ,
      text "Conditional disruption of the peroxisome proliferator-activated
 receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1,
 and apoE in macrophages and reduced cholesterol efflux." ,
      version 0 ,
      refs {
        pmid 11909955 } ,
      create-date
        str "Apr 16 2002 12:00AM" ,
      update-date
        str "Apr 28 2002  6:21PM" } ,
    {
      type generif ,
      text "in the presence of apoE, overexpression of ABCA1 modulates HDL as
 well as apoB-containing lipoprotein metabolism and reduces atherosclerosis in
 vivo" ,
      version 0 ,
      refs {
        pmid 11752403 } ,
      create-date
        str "Apr  2 2002 12:00AM" ,
      update-date
        str "Apr 28 2002  6:21PM" } ,
    {
      type generif ,
      text "ABCA1 is expressed in a pattern consistent with its role in HDL-C
 metabolism" ,
      version 0 ,
      refs {
        pmid 11896206 } ,
      create-date
        str "Mar 27 2002 12:00AM" ,
      update-date
        str "Apr  8 2002  3:24PM" } ,
    {
      type generif ,
      text "unsaturated fatty acids reduce the macrophage ABCA1 content by
 enhancing its degradation rate" ,
      version 0 ,
      refs {
        pmid 11741998 } ,
      create-date
        str "Mar  5 2002 12:00AM" ,
      update-date
        str "Apr  1 2002  5:34AM" } ,
    {
      type comment ,
      heading "Alleles" ,
      version 0 ,
      comment {
        {
          type comment ,
          text "The following allele types are documented at Mouse Genome
 Informatics" ,
          version 0 ,
          source {
            {
              anchor "(MGI)" ,
              url "http://www.informatics.jax.org/searches/allele_report.cgi?m
arkerID=MGI:99607" } } } ,
        {
          type comment ,
          heading "Targeted (knock-out) (2)" ,
          version 0 ,
          refs {
            pmid 10760292 ,
            pmid 10980140 } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11303 } ,
    {
      db "MGI" ,
      tag
        id 99607 } } ,
  xtra-index-terms {
    "LOC11303" } }
Entrezgene ::= {
  track-info {
    geneid 11304 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 15 ,
        hour 9 ,
        minute 44 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Mus musculus" ,
      common "house mouse" ,
      db {
        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
            genus "Mus" ,
            species "musculus" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
        gcode 1 ,
        mgcode 2 ,
        div "ROD" } } ,
    subtype {
      {
        subtype chromosome ,
        name "3" } } } ,
  gene {
    locus "Abca4" ,
    desc "ATP-binding cassette, sub-family A (ABC1), member 4" ,
    maploc "3 61.8 cM" ,
    syn {
      "RmP" ,
      "Abcr" ,
      "Abc10" ,
      "D430003I15Rik" } ,
    locus-tag "MGI:109424" } ,
  prot {
    name {
      "ATP-binding cassette, sub-family A, member 4" ,
      "Rim protein" ,
      "ATP-binding cassette 10" } } ,
  summary "The membrane-associated protein encoded by this gene is a member of
 the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins
 transport various molecules across extra- and intracellular membranes. ABC
 genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD,
 OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members
 of the ABC1 subfamily comprise the only major ABC subfamily found exclusively
 in multicellular eukaryotes. This protein was the first of the ABC
 transporters to be observed in photoreceptors and may play a role in the
 photoresponse. Mutations in the human gene are found in patients diagnosed
 with Stargardt disease and are associated with retinitis pigmentosa-19 and
 macular degeneration age-related 2." ,
  location {
    {
      display-str "3 G1" ,
      method
        map-type cyto } ,
    {
      display-str "3 61.8 cM" ,
      method
        map-type cM } } ,
  gene-source {
    src "LocusLink" ,
    src-int 11304 ,
    src-str2 "11304" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000069" ,
      version 1 ,
      seqs {
        int {
          from 122426366 ,
          to 122561663 ,
          strand plus ,
          id
            gi 51860767 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007378" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 122426366 ,
                to 122426518 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122434867 ,
                to 122434960 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122436157 ,
                to 122436298 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122437283 ,
                to 122437422 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122444741 ,
                to 122444868 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122451134 ,
                to 122451331 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122462504 ,
                to 122462593 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122465447 ,
                to 122465687 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122467129 ,
                to 122467268 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122468154 ,
                to 122468270 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122468889 ,
                to 122469086 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122484278 ,
                to 122484483 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122485037 ,
                to 122485213 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122486910 ,
                to 122487132 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122492064 ,
                to 122492285 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122493968 ,
                to 122494172 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122498257 ,
                to 122498322 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122501632 ,
                to 122501721 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122503233 ,
                to 122503407 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122505161 ,
                to 122505292 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122507723 ,
                to 122507862 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122508424 ,
                to 122508561 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122509727 ,
                to 122509920 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122510918 ,
                to 122511002 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122514126 ,
                to 122514331 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122514655 ,
                to 122514703 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122516604 ,
                to 122516866 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122518583 ,
                to 122518707 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122519172 ,
                to 122519270 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122520026 ,
                to 122520212 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122523293 ,
                to 122523387 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122525002 ,
                to 122525034 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122528800 ,
                to 122528905 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122529033 ,
                to 122529107 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122529332 ,
                to 122529501 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122530477 ,
                to 122530654 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122536879 ,
                to 122536994 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122537940 ,
                to 122538087 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122539437 ,
                to 122539560 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122539916 ,
                to 122540045 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122543903 ,
                to 122544023 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122544463 ,
                to 122544525 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122545390 ,
                to 122545496 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122548250 ,
                to 122548391 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122551495 ,
                to 122551629 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122552344 ,
                to 122552447 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122552531 ,
                to 122552623 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122555381 ,
                to 122555630 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122557676 ,
                to 122557762 ,
                strand plus ,
                id
                  gi 51860767 } ,
              int {
                from 122561316 ,
                to 122561663 ,
                strand plus ,
                id
                  gi 51860767 } } } ,
          seqs {
            whole
              gi 6671494 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031404" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 122426453 ,
                    to 122426518 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122434867 ,
                    to 122434960 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122436157 ,
                    to 122436298 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122437283 ,
                    to 122437422 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122444741 ,
                    to 122444868 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122451134 ,
                    to 122451331 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122462504 ,
                    to 122462593 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122465447 ,
                    to 122465687 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122467129 ,
                    to 122467268 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122468154 ,
                    to 122468270 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122468889 ,
                    to 122469086 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122484278 ,
                    to 122484483 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122485037 ,
                    to 122485213 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122486910 ,
                    to 122487132 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122492064 ,
                    to 122492285 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122493968 ,
                    to 122494172 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122498257 ,
                    to 122498322 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122501632 ,
                    to 122501721 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122503233 ,
                    to 122503407 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122505161 ,
                    to 122505292 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122507723 ,
                    to 122507862 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122508424 ,
                    to 122508561 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122509727 ,
                    to 122509920 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122510918 ,
                    to 122511002 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122514126 ,
                    to 122514331 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122514655 ,
                    to 122514703 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122516604 ,
                    to 122516866 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122518583 ,
                    to 122518707 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122519172 ,
                    to 122519270 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122520026 ,
                    to 122520212 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122523293 ,
                    to 122523387 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122525002 ,
                    to 122525034 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122528800 ,
                    to 122528905 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122529033 ,
                    to 122529107 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122529332 ,
                    to 122529501 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122530477 ,
                    to 122530654 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122536879 ,
                    to 122536994 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122537940 ,
                    to 122538087 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122539437 ,
                    to 122539560 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122539916 ,
                    to 122540045 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122543903 ,
                    to 122544023 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122544463 ,
                    to 122544525 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122545390 ,
                    to 122545496 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122548250 ,
                    to 122548391 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122551495 ,
                    to 122551629 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122552344 ,
                    to 122552447 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122552531 ,
                    to 122552623 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122555381 ,
                    to 122555630 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122557676 ,
                    to 122557762 ,
                    strand plus ,
                    id
                      gi 51860767 } ,
                  {
                    from 122561316 ,
                    to 122561435 ,
                    strand plus ,
                    id
                      gi 51860767 } } } ,
              seqs {
                whole
                  gi 6671495 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_039240" ,
      version 3 ,
      seqs {
        int {
          from 8569036 ,
          to 8704333 ,
          strand plus ,
          id
            gi 51708444 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007378" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 8569036 ,
                to 8569188 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8577537 ,
                to 8577630 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8578827 ,
                to 8578968 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8579953 ,
                to 8580092 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8587411 ,
                to 8587538 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8593804 ,
                to 8594001 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8605174 ,
                to 8605263 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8608117 ,
                to 8608357 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8609799 ,
                to 8609938 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8610824 ,
                to 8610940 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8611559 ,
                to 8611756 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8626948 ,
                to 8627153 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8627707 ,
                to 8627883 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8629580 ,
                to 8629802 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8634734 ,
                to 8634955 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8636638 ,
                to 8636842 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8640927 ,
                to 8640992 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8644302 ,
                to 8644391 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8645903 ,
                to 8646077 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8647831 ,
                to 8647962 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8650393 ,
                to 8650532 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8651094 ,
                to 8651231 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8652397 ,
                to 8652590 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8653588 ,
                to 8653672 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8656796 ,
                to 8657001 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8657325 ,
                to 8657373 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8659274 ,
                to 8659536 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8661253 ,
                to 8661377 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8661842 ,
                to 8661940 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8662696 ,
                to 8662882 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8665963 ,
                to 8666057 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8667672 ,
                to 8667704 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8671470 ,
                to 8671575 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8671703 ,
                to 8671777 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8672002 ,
                to 8672171 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8673147 ,
                to 8673324 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8679549 ,
                to 8679664 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8680610 ,
                to 8680757 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8682107 ,
                to 8682230 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8682586 ,
                to 8682715 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8686573 ,
                to 8686693 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8687133 ,
                to 8687195 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8688060 ,
                to 8688166 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8690920 ,
                to 8691061 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8694165 ,
                to 8694299 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8695014 ,
                to 8695117 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8695201 ,
                to 8695293 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8698051 ,
                to 8698300 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8700346 ,
                to 8700432 ,
                strand plus ,
                id
                  gi 51708444 } ,
              int {
                from 8703986 ,
                to 8704333 ,
                strand plus ,
                id
                  gi 51708444 } } } ,
          seqs {
            whole
              gi 6671494 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031404" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 8569123 ,
                    to 8569188 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8577537 ,
                    to 8577630 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8578827 ,
                    to 8578968 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8579953 ,
                    to 8580092 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8587411 ,
                    to 8587538 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8593804 ,
                    to 8594001 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8605174 ,
                    to 8605263 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8608117 ,
                    to 8608357 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8609799 ,
                    to 8609938 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8610824 ,
                    to 8610940 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8611559 ,
                    to 8611756 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8626948 ,
                    to 8627153 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8627707 ,
                    to 8627883 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8629580 ,
                    to 8629802 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8634734 ,
                    to 8634955 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8636638 ,
                    to 8636842 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8640927 ,
                    to 8640992 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8644302 ,
                    to 8644391 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8645903 ,
                    to 8646077 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8647831 ,
                    to 8647962 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8650393 ,
                    to 8650532 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8651094 ,
                    to 8651231 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8652397 ,
                    to 8652590 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8653588 ,
                    to 8653672 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8656796 ,
                    to 8657001 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8657325 ,
                    to 8657373 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8659274 ,
                    to 8659536 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8661253 ,
                    to 8661377 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8661842 ,
                    to 8661940 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8662696 ,
                    to 8662882 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8665963 ,
                    to 8666057 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8667672 ,
                    to 8667704 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8671470 ,
                    to 8671575 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8671703 ,
                    to 8671777 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8672002 ,
                    to 8672171 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8673147 ,
                    to 8673324 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8679549 ,
                    to 8679664 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8680610 ,
                    to 8680757 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8682107 ,
                    to 8682230 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8682586 ,
                    to 8682715 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8686573 ,
                    to 8686693 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8687133 ,
                    to 8687195 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8688060 ,
                    to 8688166 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8690920 ,
                    to 8691061 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8694165 ,
                    to 8694299 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8695014 ,
                    to 8695117 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8695201 ,
                    to 8695293 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8698051 ,
                    to 8698300 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8700346 ,
                    to 8700432 ,
                    strand plus ,
                    id
                      gi 51708444 } ,
                  {
                    from 8703986 ,
                    to 8704105 ,
                    strand plus ,
                    id
                      gi 51708444 } } } ,
              seqs {
                whole
                  gi 6671495 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "Mouse Genome Informatics" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "Abca4" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "ATP-binding cassette, sub-family A (ABC1), member 4" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "MGI" ,
          url "http://www.informatics.jax.org/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5524 } ,
                  anchor "ATP binding" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16887 } ,
                  anchor "ATPase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9202155 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 42626 } ,
                  anchor "ATPase activity, coupled to transmembrane movement
 of substances" ,
                  post-text "evidence: TAS" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 10412977 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5548 } ,
                  anchor "phospholipid transporter activity" ,
                  post-text "evidence: IMP" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 10412977 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 4012 } ,
                  anchor "phospholipid-translocating ATPase activity" ,
                  post-text "evidence: IMP" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 10412977 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6649 } ,
                  anchor "phospholipid transfer to membrane" ,
                  post-text "evidence: IMP" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 11431429 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 45494 } ,
                  anchor "photoreceptor maintenance" ,
                  post-text "evidence: IMP" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 7600 } ,
                  anchor "sensory perception" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6810 } ,
                  anchor "transport" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 10412977 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 7601 } ,
                  anchor "visual perception" ,
                  post-text "evidence: IMP" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16021 } ,
                  anchor "integral to membrane" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 9202155 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5887 } ,
                  anchor "integral to plasma membrane" ,
                  post-text "evidence: TAS" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Human, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 298 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=3&
MAPS=genes-r-org/human-chr/mouse%3A3,genes-r-org/rat-chr/mouse%3A3,genes-r-org
/mouse-chr3&query=e%3A11304[id]+AND+gene[obj_type]&QSTR=abca4&cmd=focus&fill=1
0" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "MGI" ,
            tag
              id 109424 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "REVIEWED" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 12477932 ,
        pmid 12466851 ,
        pmid 11431429 ,
        pmid 11217851 ,
        pmid 11076861 ,
        pmid 11042159 ,
        pmid 10852960 ,
        pmid 10412977 ,
        pmid 10349636 ,
        pmid 9202155 ,
        pmid 8889548 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 140994 } ,
              anchor "Abca4" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "MGI:8523" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 159184 } ,
              anchor "AF000149" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "192133" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "693384" ,
              version 0 } ,
            {
              type other ,
              label "Alternate name" ,
              text "ND" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_007378" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 6671494 } ,
              anchor "NM_007378" } } ,
          seqs {
            whole
              gi 6671494 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_031404" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 6671495 } ,
                  anchor "NP_031404" ,
                  post-text "ATP-binding cassette, sub-family A, member 4" } } ,
              seqs {
                whole
                  gi 6671495 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 6671495 } ,
                      pre-text "(3)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5341 } ,
                          anchor "cd00267: ABC_ATPase; ABC (ATP-binding
 cassette) transporter nucleotide-binding domain" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 931 - 1144  Blast Score: 454" ,
                          version 0 } ,
                        {
                          type other ,
                          text "Location: 1937 - 2152  Blast Score: 353" ,
                          version 0 } } } ,
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 13428 } ,
                          anchor "COG4152: COG4152; ABC-type uncharacterized
 transport system, ATPase component [General function prediction only]" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 1937 - 2253  Blast Score: 387" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "AF000149" } ,
                  anchor "AF000149" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AF000149" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 3243083 } ,
              anchor "AF000149" } } ,
          seqs {
            whole
              gi 3243083 } ,
          products {
            {
              type peptide ,
              accession "AAC23916" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 2547314 } ,
                  anchor "AAC23916" } } ,
              seqs {
                whole
                  gi 2547314 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK053043" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 26095532 } ,
              anchor "AK053043" } } ,
          seqs {
            whole
              gi 26095532 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK084860" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 26102289 } ,
              anchor "AK084860" } } ,
          seqs {
            whole
              gi 26102289 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC043937" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 27882179 } ,
              anchor "BC043937" } } ,
          seqs {
            whole
              gi 27882179 } ,
          products {
            {
              type peptide ,
              accession "AAH43937" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 27882180 } ,
                  anchor "AAH43937" } } ,
              seqs {
                whole
                  gi 27882180 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC057853" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 34783941 } ,
              anchor "BC057853" } } ,
          seqs {
            whole
              gi 34783941 } ,
          products {
            {
              type peptide ,
              accession "AAH57853" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 34783942 } ,
                  anchor "AAH57853" } } ,
              seqs {
                whole
                  gi 34783942 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "11304" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont
ig=NT_039240.3&gene=Abca4&lid=11304&from=8569037&to=8704334" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "11304" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10
090&contig=NT_039240.3&gene=Abca4&lid=11304" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Mm.3918" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Mm.3918" } ,
              anchor "Mm.3918" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=39
18" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "11304" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
11304[loc]&TAXID=10090" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGI" ,
                tag
                  id 109424 } ,
              anchor "MGI" ,
              url "http://www.informatics.jax.org/searches/accession_report.cg
i?id=MGI:109424" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC057
853" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position=
BC057853" } } } ,
        {
          type comment ,
          text "Human ABC-Transporter Proteins" ,
          version 0 ,
          source {
            {
              src {
                db "Human ABC-Transporter Proteins" ,
                tag
                  str "Human ABC-Transporter Proteins" } ,
              anchor "Human ABC-Transporter Proteins" ,
              url "http://nutrigene.4t.com/humanabc.htm" } } } } } ,
    {
      type comment ,
      heading "Alleles" ,
      version 0 ,
      comment {
        {
          type comment ,
          text "The following allele types are documented at Mouse Genome
 Informatics" ,
          version 0 ,
          source {
            {
              anchor "(MGI)" ,
              url "http://www.informatics.jax.org/searches/allele_report.cgi?m
arkerID=MGI:109424" } } } ,
        {
          type comment ,
          heading "Targeted (knock-out) (1)" ,
          version 0 ,
          refs {
            pmid 10412977 } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11304 } ,
    {
      db "MGI" ,
      tag
        id 109424 } } ,
  xtra-index-terms {
    "LOC11304" } }
Entrezgene ::= {
  track-info {
    geneid 11305 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 2 ,
        day 17 ,
        hour 12 ,
        minute 54 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Mus musculus" ,
      common "house mouse" ,
      db {
        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
            genus "Mus" ,
            species "musculus" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
        gcode 1 ,
        mgcode 2 ,
        div "ROD" } } ,
    subtype {
      {
        subtype chromosome ,
        name "2" } } } ,
  gene {
    locus "Abca2" ,
    desc "ATP-binding cassette, sub-family A (ABC1), member 2" ,
    maploc "2 12.6 cM" ,
    syn {
      "Abc2" ,
      "mKIAA1062" ,
      "D2H0S1474E" } ,
    locus-tag "MGI:99606" } ,
  prot {
    name {
      "ATP-binding cassette, sub-family A (ABC1), member 2" ,
      "ATP-binding cassette 2" } } ,
  location {
    {
      display-str "2 A2-B" ,
      method
        map-type cyto } ,
    {
      display-str "2 12.6 cM" ,
      method
        map-type cM } } ,
  gene-source {
    src "LocusLink" ,
    src-int 11305 ,
    src-str2 "11305" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000068" ,
      version 1 ,
      seqs {
        int {
          from 25388791 ,
          to 25408220 ,
          strand plus ,
          id
            gi 51860766 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007379" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 25388791 ,
                to 25388856 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25392017 ,
                to 25392110 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25393119 ,
                to 25393230 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25393315 ,
                to 25393478 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25393703 ,
                to 25393830 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25393985 ,
                to 25394095 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25394330 ,
                to 25394548 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25394911 ,
                to 25395278 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25395520 ,
                to 25395679 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25396389 ,
                to 25396517 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25396610 ,
                to 25396774 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25396851 ,
                to 25396947 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25397266 ,
                to 25397439 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25397509 ,
                to 25397611 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25397686 ,
                to 25397800 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25397914 ,
                to 25398104 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25398252 ,
                to 25398402 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25398479 ,
                to 25398683 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25398822 ,
                to 25398986 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25399088 ,
                to 25399268 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25399348 ,
                to 25399560 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25400546 ,
                to 25400742 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25400831 ,
                to 25401013 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25401209 ,
                to 25401393 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25401500 ,
                to 25401620 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25401896 ,
                to 25402132 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25402212 ,
                to 25402418 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25402671 ,
                to 25402773 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25402856 ,
                to 25403175 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25403250 ,
                to 25403463 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25403550 ,
                to 25403655 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25403747 ,
                to 25403858 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25403948 ,
                to 25404008 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25404091 ,
                to 25404265 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25404346 ,
                to 25404461 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25404543 ,
                to 25404690 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25404835 ,
                to 25404958 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25405093 ,
                to 25405225 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25405329 ,
                to 25405446 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25405571 ,
                to 25405749 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25405991 ,
                to 25406132 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25406232 ,
                to 25406366 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25406459 ,
                to 25406562 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25406636 ,
                to 25406728 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25406812 ,
                to 25406914 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25406999 ,
                to 25407136 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25407221 ,
                to 25407421 ,
                strand plus ,
                id
                  gi 51860766 } ,
              int {
                from 25407862 ,
                to 25408220 ,
                strand plus ,
                id
                  gi 51860766 } } } ,
          seqs {
            whole
              gi 11993938 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031405" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 25388791 ,
                    to 25388856 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25392017 ,
                    to 25392110 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25393119 ,
                    to 25393230 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25393315 ,
                    to 25393478 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25393703 ,
                    to 25393830 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25393985 ,
                    to 25394095 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25394330 ,
                    to 25394548 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25394911 ,
                    to 25395278 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25395520 ,
                    to 25395679 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25396389 ,
                    to 25396517 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25396610 ,
                    to 25396774 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25396851 ,
                    to 25396947 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25397266 ,
                    to 25397439 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25397509 ,
                    to 25397611 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25397686 ,
                    to 25397800 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25397914 ,
                    to 25398104 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25398252 ,
                    to 25398402 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25398479 ,
                    to 25398683 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25398822 ,
                    to 25398986 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25399088 ,
                    to 25399268 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25399348 ,
                    to 25399560 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25400546 ,
                    to 25400742 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25400831 ,
                    to 25401013 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25401209 ,
                    to 25401393 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25401500 ,
                    to 25401620 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25401896 ,
                    to 25402132 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25402212 ,
                    to 25402418 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25402671 ,
                    to 25402773 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25402856 ,
                    to 25403175 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25403250 ,
                    to 25403463 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25403550 ,
                    to 25403655 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25403747 ,
                    to 25403858 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25403948 ,
                    to 25404008 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25404091 ,
                    to 25404265 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25404346 ,
                    to 25404461 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25404543 ,
                    to 25404690 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25404835 ,
                    to 25404958 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25405093 ,
                    to 25405225 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25405329 ,
                    to 25405446 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25405571 ,
                    to 25405749 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25405991 ,
                    to 25406132 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25406232 ,
                    to 25406366 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25406459 ,
                    to 25406562 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25406636 ,
                    to 25406728 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25406812 ,
                    to 25406914 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25406999 ,
                    to 25407136 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25407221 ,
                    to 25407421 ,
                    strand plus ,
                    id
                      gi 51860766 } ,
                  {
                    from 25407862 ,
                    to 25407897 ,
                    strand plus ,
                    id
                      gi 51860766 } } } ,
              seqs {
                whole
                  gi 11993939 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_039206" ,
      version 3 ,
      seqs {
        int {
          from 2857415 ,
          to 2876844 ,
          strand plus ,
          id
            gi 51706164 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "NM_007379" ,
          version 1 ,
          genomic-coords {
            mix {
              int {
                from 2857415 ,
                to 2857480 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2860641 ,
                to 2860734 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2861743 ,
                to 2861854 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2861939 ,
                to 2862102 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2862327 ,
                to 2862454 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2862609 ,
                to 2862719 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2862954 ,
                to 2863172 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2863535 ,
                to 2863902 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2864144 ,
                to 2864303 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2865013 ,
                to 2865141 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2865234 ,
                to 2865398 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2865475 ,
                to 2865571 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2865890 ,
                to 2866063 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2866133 ,
                to 2866235 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2866310 ,
                to 2866424 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2866538 ,
                to 2866728 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2866876 ,
                to 2867026 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2867103 ,
                to 2867307 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2867446 ,
                to 2867610 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2867712 ,
                to 2867892 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2867972 ,
                to 2868184 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2869170 ,
                to 2869366 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2869455 ,
                to 2869637 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2869833 ,
                to 2870017 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2870124 ,
                to 2870244 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2870520 ,
                to 2870756 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2870836 ,
                to 2871042 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2871295 ,
                to 2871397 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2871480 ,
                to 2871799 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2871874 ,
                to 2872087 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2872174 ,
                to 2872279 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2872371 ,
                to 2872482 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2872572 ,
                to 2872632 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2872715 ,
                to 2872889 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2872970 ,
                to 2873085 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2873167 ,
                to 2873314 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2873459 ,
                to 2873582 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2873717 ,
                to 2873849 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2873953 ,
                to 2874070 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2874195 ,
                to 2874373 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2874615 ,
                to 2874756 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2874856 ,
                to 2874990 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2875083 ,
                to 2875186 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2875260 ,
                to 2875352 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2875436 ,
                to 2875538 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2875623 ,
                to 2875760 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2875845 ,
                to 2876045 ,
                strand plus ,
                id
                  gi 51706164 } ,
              int {
                from 2876486 ,
                to 2876844 ,
                strand plus ,
                id
                  gi 51706164 } } } ,
          seqs {
            whole
              gi 11993938 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "NP_031405" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 2857415 ,
                    to 2857480 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2860641 ,
                    to 2860734 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2861743 ,
                    to 2861854 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2861939 ,
                    to 2862102 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2862327 ,
                    to 2862454 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2862609 ,
                    to 2862719 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2862954 ,
                    to 2863172 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2863535 ,
                    to 2863902 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2864144 ,
                    to 2864303 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2865013 ,
                    to 2865141 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2865234 ,
                    to 2865398 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2865475 ,
                    to 2865571 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2865890 ,
                    to 2866063 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2866133 ,
                    to 2866235 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2866310 ,
                    to 2866424 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2866538 ,
                    to 2866728 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2866876 ,
                    to 2867026 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2867103 ,
                    to 2867307 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2867446 ,
                    to 2867610 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2867712 ,
                    to 2867892 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2867972 ,
                    to 2868184 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2869170 ,
                    to 2869366 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2869455 ,
                    to 2869637 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2869833 ,
                    to 2870017 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2870124 ,
                    to 2870244 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2870520 ,
                    to 2870756 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2870836 ,
                    to 2871042 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2871295 ,
                    to 2871397 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2871480 ,
                    to 2871799 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2871874 ,
                    to 2872087 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2872174 ,
                    to 2872279 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2872371 ,
                    to 2872482 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2872572 ,
                    to 2872632 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2872715 ,
                    to 2872889 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2872970 ,
                    to 2873085 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2873167 ,
                    to 2873314 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2873459 ,
                    to 2873582 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2873717 ,
                    to 2873849 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2873953 ,
                    to 2874070 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2874195 ,
                    to 2874373 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2874615 ,
                    to 2874756 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2874856 ,
                    to 2874990 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2875083 ,
                    to 2875186 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2875260 ,
                    to 2875352 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2875436 ,
                    to 2875538 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2875623 ,
                    to 2875760 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2875845 ,
                    to 2876045 ,
                    strand plus ,
                    id
                      gi 51706164 } ,
                  {
                    from 2876486 ,
                    to 2876521 ,
                    strand plus ,
                    id
                      gi 51706164 } } } ,
              seqs {
                whole
                  gi 11993939 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "Mouse Genome Informatics" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "Abca2" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "ATP-binding cassette, sub-family A (ABC1), member 2" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "MGI" ,
          url "http://www.informatics.jax.org/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5524 } ,
                  anchor "ATP binding" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16887 } ,
                  anchor "ATPase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12466851 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5215 } ,
                  anchor "transporter activity" ,
                  post-text "evidence: ISS" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 8203 } ,
                  anchor "cholesterol metabolism" ,
                  post-text "evidence: ISS" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6810 } ,
                  anchor "transport" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              refs {
                pmid 12466851 } ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16021 } ,
                  anchor "integral to membrane" ,
                  post-text "evidence: TAS" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5765 } ,
                  anchor "lysosomal membrane" ,
                  post-text "evidence: ISS" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Human, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 55590 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=2&
MAPS=genes-r-org/human-chr/mouse%3A2,genes-r-org/rat-chr/mouse%3A2,genes-r-org
/mouse-chr2&query=e%3A11305[id]+AND+gene[obj_type]&QSTR=abca2&cmd=focus&fill=1
0" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "MGI" ,
            tag
              id 99606 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "PROVISIONAL" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 14621295 ,
        pmid 12466851 ,
        pmid 8088782 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 158928 } ,
              anchor "AI413825" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "421529" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_007379" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 11993938 } ,
              anchor "NM_007379" } } ,
          seqs {
            whole
              gi 11993938 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_031405" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 11993939 } ,
                  anchor "NP_031405" ,
                  post-text "ATP-binding cassette, sub-family A (ABC1), member
 2" } } ,
              seqs {
                whole
                  gi 11993939 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 11993939 } ,
                      pre-text "(2)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5341 } ,
                          anchor "cd00267: ABC_ATPase; ABC (ATP-binding
 cassette) transporter nucleotide-binding domain" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 1018 - 1205  Blast Score: 389" ,
                          version 0 } ,
                        {
                          type other ,
                          text "Location: 2051 - 2269  Blast Score: 372" ,
                          version 0 } } } } } } } } ,
          comment {
            {
              type other ,
              heading "Source Sequence" ,
              version 0 ,
              source {
                {
                  src {
                    db "Nucleotide" ,
                    tag
                      str "X75927" } ,
                  anchor "X75927" } } ,
              comment {
                {
                  type other ,
                  version 0 } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK129274" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 37360211 } ,
              anchor "AK129274" } } ,
          seqs {
            whole
              gi 37360211 } ,
          products {
            {
              type peptide ,
              accession "BAC98084" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 37360212 } ,
                  anchor "BAC98084" } } ,
              seqs {
                whole
                  gi 37360212 } } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "X75927" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 11990230 } ,
              anchor "X75927" } } ,
          seqs {
            whole
              gi 11990230 } ,
          products {
            {
              type peptide ,
              accession "CAA53531" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 11990231 } ,
                  anchor "CAA53531" } } ,
              seqs {
                whole
                  gi 11990231 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "DBA/2" ,
              version 0 } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "P41234" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 14916951 } ,
                  anchor "P41234" } } ,
              seqs {
                whole
                  gi 14916951 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "11305" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont
ig=NT_039206.3&gene=Abca2&lid=11305&from=2857416&to=2876845" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "11305" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10
090&contig=NT_039206.3&gene=Abca2&lid=11305" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Mm.2210" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Mm.2210" } ,
              anchor "Mm.2210" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=22
10" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "11305" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
11305[loc]&TAXID=10090" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGI" ,
                tag
                  id 99606 } ,
              anchor "MGI" ,
              url "http://www.informatics.jax.org/searches/accession_report.cg
i?id=MGI:99606" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Mus_musculus/contigview?geneid=X7592
7" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position=
X75927" } } } ,
        {
          type comment ,
          text "Human ABC-Transporter Proteins" ,
          version 0 ,
          source {
            {
              src {
                db "Human ABC-Transporter Proteins" ,
                tag
                  str "Human ABC-Transporter Proteins" } ,
              anchor "Human ABC-Transporter Proteins" ,
              url "http://nutrigene.4t.com/humanabc.htm" } } } } } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11305 } ,
    {
      db "MGI" ,
      tag
        id 99606 } } ,
  xtra-index-terms {
    "LOC11305" } }
Entrezgene ::= {
  track-info {
    geneid 11306 ,
    status live ,
    create-date
      std {
        year 2003 ,
        month 8 ,
        day 28 ,
        hour 21 ,
        minute 39 ,
        second 0 } ,
    update-date
      std {
        year 2005 ,
        month 4 ,
        day 19 ,
        hour 12 ,
        minute 12 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Mus musculus" ,
      common "house mouse" ,
      db {
        {
          db "taxon" ,
          tag
            id 10090 } } ,
      syn {
        "mouse" } ,
      orgname {
        name
          binomial {
            genus "Mus" ,
            species "musculus" } ,
        lineage "Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;
 Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
 Sciurognathi; Muridae; Murinae; Mus" ,
        gcode 1 ,
        mgcode 2 ,
        div "ROD" } } ,
    subtype {
      {
        subtype chromosome ,
        name "X" } } } ,
  gene {
    locus "Abcb7" ,
    desc "ATP-binding cassette, sub-family B (MDR/TAP), member 7" ,
    maploc "X 39.0 cM" ,
    syn {
      "Abc7" } ,
    locus-tag "MGI:109533" } ,
  prot {
    name {
      "ATP-binding cassette, sub-family B (MDR/TAP), member 7" ,
      "ATP-binding cassette 7" } } ,
  location {
    {
      display-str "X C-D" ,
      method
        map-type cyto } ,
    {
      display-str "X 39.0 cM" ,
      method
        map-type cM } } ,
  gene-source {
    src "LocusLink" ,
    src-int 11306 ,
    src-str2 "11306" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      heading "Reference" ,
      accession "NC_000086" ,
      version 1 ,
      seqs {
        int {
          from 95684235 ,
          to 95817474 ,
          strand minus ,
          id
            gi 51869957 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "XM_356348" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 95684235 ,
                to 95687836 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95694701 ,
                to 95694808 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95698046 ,
                to 95698149 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95699409 ,
                to 95699580 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95703347 ,
                to 95703476 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95703628 ,
                to 95703791 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95704349 ,
                to 95704506 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95705372 ,
                to 95705546 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95706530 ,
                to 95706617 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95706707 ,
                to 95706795 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95707710 ,
                to 95707978 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95708848 ,
                to 95708980 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95726912 ,
                to 95727031 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95746072 ,
                to 95746158 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95748503 ,
                to 95748580 ,
                strand minus ,
                id
                  gi 51869957 } ,
              int {
                from 95817235 ,
                to 95817474 ,
                strand minus ,
                id
                  gi 51869957 } } } ,
          seqs {
            whole
              gi 51772276 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "XP_356348" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 95687621 ,
                    to 95687836 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95694701 ,
                    to 95694808 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95698046 ,
                    to 95698149 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95699409 ,
                    to 95699580 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95703347 ,
                    to 95703476 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95703628 ,
                    to 95703791 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95704349 ,
                    to 95704506 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95705372 ,
                    to 95705546 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95706530 ,
                    to 95706617 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95706707 ,
                    to 95706795 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95707710 ,
                    to 95707978 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95708848 ,
                    to 95708980 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95726912 ,
                    to 95727031 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95746072 ,
                    to 95746158 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95748503 ,
                    to 95748580 ,
                    strand minus ,
                    id
                      gi 51869957 } ,
                  {
                    from 95817235 ,
                    to 95817474 ,
                    strand minus ,
                    id
                      gi 51869957 } } } ,
              seqs {
                whole
                  gi 38086485 } } } } } } ,
    {
      type genomic ,
      heading "Reference" ,
      accession "NT_039711" ,
      version 3 ,
      seqs {
        int {
          from 9312469 ,
          to 9445708 ,
          strand minus ,
          id
            gi 51772331 } } ,
      products {
        {
          type mRNA ,
          heading "Reference" ,
          accession "XM_356348" ,
          version 2 ,
          genomic-coords {
            mix {
              int {
                from 9312469 ,
                to 9316070 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9322935 ,
                to 9323042 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9326280 ,
                to 9326383 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9327643 ,
                to 9327814 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9331581 ,
                to 9331710 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9331862 ,
                to 9332025 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9332583 ,
                to 9332740 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9333606 ,
                to 9333780 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9334764 ,
                to 9334851 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9334941 ,
                to 9335029 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9335944 ,
                to 9336212 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9337082 ,
                to 9337214 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9355146 ,
                to 9355265 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9374306 ,
                to 9374392 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9376737 ,
                to 9376814 ,
                strand minus ,
                id
                  gi 51772331 } ,
              int {
                from 9445469 ,
                to 9445708 ,
                strand minus ,
                id
                  gi 51772331 } } } ,
          seqs {
            whole
              gi 51772276 } ,
          products {
            {
              type peptide ,
              heading "Reference" ,
              accession "XP_356348" ,
              version 1 ,
              genomic-coords {
                packed-int {
                  {
                    from 9315855 ,
                    to 9316070 ,
                    strand minus ,
                    id
                      gi 51772331 } ,
                  {
                    from 9322935 ,
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                      gi 51772331 } ,
                  {
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                      gi 51772331 } ,
                  {
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                      gi 51772331 } ,
                  {
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                  {
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                    id
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                  {
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                      gi 51772331 } ,
                  {
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                    strand minus ,
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                      gi 51772331 } ,
                  {
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                      gi 51772331 } ,
                  {
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                      gi 51772331 } ,
                  {
                    from 9337082 ,
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                  {
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                    id
                      gi 51772331 } ,
                  {
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                  {
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                      gi 51772331 } ,
                  {
                    from 9445469 ,
                    to 9445708 ,
                    strand minus ,
                    id
                      gi 51772331 } } } ,
              seqs {
                whole
                  gi 38086485 } } } } } } } ,
  properties {
    {
      type comment ,
      label "Nomenclature" ,
      version 0 ,
      source {
        {
          anchor "Mouse Genome Informatics" } } ,
      properties {
        {
          type property ,
          label "Official Symbol" ,
          text "Abcb7" ,
          version 0 } ,
        {
          type property ,
          label "Official Full Name" ,
          text "ATP-binding cassette, sub-family B (MDR/TAP), member 7" ,
          version 0 } } } ,
    {
      type comment ,
      heading "GeneOntology" ,
      version 0 ,
      source {
        {
          pre-text "Provided by" ,
          anchor "MGI" ,
          url "http://www.informatics.jax.org/" } } ,
      comment {
        {
          type comment ,
          label "Function" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5524 } ,
                  anchor "ATP binding" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16887 } ,
                  anchor "ATPase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 42626 } ,
                  anchor "ATPase activity, coupled to transmembrane movement
 of substances" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 17111 } ,
                  anchor "nucleoside-triphosphatase activity" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 166 } ,
                  anchor "nucleotide binding" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Process" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 6810 } ,
                  anchor "transport" ,
                  post-text "evidence: IEA" } } } } } ,
        {
          type comment ,
          label "Component" ,
          version 0 ,
          comment {
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 19866 } ,
                  anchor "inner membrane" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16021 } ,
                  anchor "integral to membrane" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 16020 } ,
                  anchor "membrane" ,
                  post-text "evidence: IEA" } } } ,
            {
              type comment ,
              version 0 ,
              source {
                {
                  src {
                    db "GO" ,
                    tag
                      id 5739 } ,
                  anchor "mitochondrion" ,
                  post-text "evidence: IEA" } } } } } } } } ,
  homology {
    {
      type comment ,
      heading "Human, Rat" ,
      version 0 ,
      source {
        {
          src {
            db "HomoloGene" ,
            tag
              id 3175 } ,
          anchor "Map Viewer" ,
          url "http://www.ncbi.nlm.nih.gov/mapview/maps.cgi?taxid=10090&chr=X&
MAPS=genes-r-org/human-chr/mouse%3AX,genes-r-org/rat-chr/mouse%3AX,genes-r-org
/mouse-chrX&query=e%3A11306[id]+AND+gene[obj_type]&QSTR=abcb7&cmd=focus&fill=1
0" } } } } ,
  comments {
    {
      type comment ,
      heading "LocusTagLink" ,
      version 0 ,
      source {
        {
          src {
            db "MGI" ,
            tag
              id 109533 } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "MODEL" ,
      version 0 } ,
    {
      type comment ,
      version 0 ,
      refs {
        pmid 14651853 ,
        pmid 12480705 ,
        pmid 12477932 ,
        pmid 11217851 ,
        pmid 11076861 ,
        pmid 11042159 ,
        pmid 10922068 ,
        pmid 10349636 ,
        pmid 9143506 } } ,
    {
      type comment ,
      heading "Markers (Sequence Tagged Sites/STS)" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 161105 } ,
              anchor "RH124283" ,
              post-text "(e-PCR)" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 178992 } ,
              anchor "AW537380" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "953972" ,
              version 0 } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UniSTS" ,
                tag
                  id 181314 } ,
              anchor "AU019072" ,
              post-text "(e-PCR)" } } ,
          comment {
            {
              type other ,
              label "Alternate name" ,
              text "359130" ,
              version 0 } } } } } ,
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "XM_356348" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 51772276 } ,
              anchor "XM_356348" } } ,
          seqs {
            whole
              gi 51772276 } ,
          products {
            {
              type peptide ,
              accession "XP_356348" ,
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              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 38086485 } ,
                  anchor "XP_356348" } } ,
              seqs {
                whole
                  gi 38086485 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 38086485 } ,
                      pre-text "(3)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
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                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5341 } ,
                          anchor "cd00267: ABC_ATPase; ABC (ATP-binding
 cassette) transporter nucleotide-binding domain" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 496 - 714  Blast Score: 577" ,
                          version 0 } } } ,
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 14387 } ,
                          anchor "COG5265: ATM1; ABC-type transport system
 involved in Fe-S cluster assembly, permease and ATPase components
 [Posttranslational modification, protein turnover, chaperones]" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 234 - 729  Blast Score: 1506" ,
                          version 0 } } } ,
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 25581 } ,
                          anchor "pfam00664: ABC_membrane; ABC transporter
 transmembrane region" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 164 - 435  Blast Score: 247" ,
                          version 0 } } } } } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AA517758" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 2257282 } ,
              anchor "AA517758" } } ,
          seqs {
            whole
              gi 2257282 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J x DBA/2J F1" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK040069" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 26087598 } ,
              anchor "AK040069" } } ,
          seqs {
            whole
              gi 26087598 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AK084853" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 26102284 } ,
              anchor "AK084853" } } ,
          seqs {
            whole
              gi 26102284 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AU019072" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 3374656 } ,
              anchor "AU019072" } } ,
          seqs {
            whole
              gi 3374656 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "AW537380" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 7179797 } ,
              anchor "AW537380" } } ,
          seqs {
            whole
              gi 7179797 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "C57BL/6J" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "BC035534" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 23243450 } ,
              anchor "BC035534" } } ,
          seqs {
            whole
              gi 23243450 } ,
          products {
            {
              type peptide ,
              text "None" ,
              version 0 } } } ,
        {
          type mRNA ,
          heading "mRNA" ,
          accession "U43892" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 1167981 } ,
              anchor "U43892" } } ,
          seqs {
            whole
              gi 1167981 } ,
          products {
            {
              type peptide ,
              accession "AAC53152" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 1167982 } ,
                  anchor "AAC53152" } } ,
              seqs {
                whole
                  gi 1167982 } } } ,
          comment {
            {
              type other ,
              label "Strain" ,
              text "DBA/2" ,
              version 0 } } } ,
        {
          type other ,
          text "None" ,
          version 0 ,
          products {
            {
              type peptide ,
              accession "Q61102" ,
              version 0 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 5902709 } ,
                  anchor "Q61102" } } ,
              seqs {
                whole
                  gi 5902709 } } } } } } ,
    {
      type comment ,
      heading "Additional Links" ,
      version 0 ,
      comment {
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Evidence Viewer" ,
                tag
                  str "11306" } ,
              anchor "Evidence Viewer" ,
              url "http://www.ncbi.nlm.nih.gov/sutils/evv.cgi?taxid=10090&cont
ig=NT_039711.3&gene=Abcb7&lid=11306&from=9312470&to=9445709" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "ModelMaker" ,
                tag
                  str "11306" } ,
              anchor "ModelMaker" ,
              url "http://www.ncbi.nlm.nih.gov/mapview/modelmaker.cgi?taxid=10
090&contig=NT_039711.3&gene=Abcb7&lid=11306" } } } ,
        {
          type comment ,
          text "UniGene" ,
          version 0 ,
          xtra-properties {
            {
              tag "UNIGENE" ,
              value "Mm.262053" } } ,
          source {
            {
              src {
                db "UniGene" ,
                tag
                  str "Mm.262053" } ,
              anchor "Mm.262053" ,
              url "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=26
2053" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "HomoloGene" ,
                tag
                  str "11306" } ,
              anchor "HomoloGene" ,
              url "http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=
11306[loc]&TAXID=10090" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "MGI" ,
                tag
                  id 109533 } ,
              anchor "MGI" ,
              url "http://www.informatics.jax.org/searches/accession_report.cg
i?id=MGI:109533" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "Ensembl" ,
                tag
                  str "" } ,
              url "http://www.ensembl.org/Mus_musculus/contigview?geneid=BC035
534" } } } ,
        {
          type comment ,
          version 0 ,
          source {
            {
              src {
                db "UCSC" ,
                tag
                  str "" } ,
              url "http://genome.ucsc.edu/cgi-bin/hgTracks?org=mouse&position=
BC035534" } } } ,
        {
          type comment ,
          text "Gene Expression Database (GXD) at MGI" ,
          version 0 ,
          source {
            {
              src {
                db "Gene Expression Database (GXD) at MGI" ,
                tag
                  str "MGI:109533" } ,
              anchor "MGI:109533" ,
              url "http://www.informatics.jax.org/searches/expression_report.c
gi?id=MGI:109533" } } } ,
        {
          type comment ,
          text "Human ABC-Transporter Proteins" ,
          version 0 ,
          source {
            {
              src {
                db "Human ABC-Transporter Proteins" ,
                tag
                  str "Human ABC-Transporter Proteins" } ,
              anchor "Human ABC-Transporter Proteins" ,
              url "http://nutrigene.4t.com/humanabc.htm" } } } } } ,
    {
      type generif ,
      text "ABC7 positively regulates the expression of extramitochondrial
 thioredoxin & that of an intramitochondrial iron-sulfur-containing protein,
 ferrochelatase. ABC7 contributes to the production of heme during the
 differentiation of erythroid cells." ,
      version 0 ,
      refs {
        pmid 12480705 } ,
      create-date
        str "May 23 2003 12:00AM" ,
      update-date
        str "Jun 22 2003  7:07AM" } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 11306 } ,
    {
      db "MGI" ,
      tag
        id 109533 } } ,
  xtra-index-terms {
    "LOC11306" } }
Entrezgene ::= {
  track-info {
    geneid 171590 ,
    status live ,
    create-date
      std {
        year 2005 ,
        month 4 ,
        day 7 ,
        hour 13 ,
        minute 32 ,
        second 25 } ,
    update-date
      std {
        year 2005 ,
        month 1 ,
        day 18 ,
        hour 23 ,
        minute 7 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Caenorhabditis elegans" ,
      db {
        {
          db "taxon" ,
          tag
            id 6239 } } ,
      orgname {
        name
          binomial {
            genus "Caenorhabditis" ,
            species "elegans" } ,
        lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida;
 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" ,
        gcode 1 ,
        mgcode 5 ,
        div "INV" } } ,
    subtype {
      {
        subtype chromosome ,
        name "I" } } } ,
  gene {
    locus "1A478" ,
    maploc "I;-17.75 cM (interpolated genetic position)" ,
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      {
        db "AceView/WormGenes" ,
        tag
          str "1A478" } ,
      {
        db "LocusID" ,
        tag
          id 171590 } ,
      {
        db "WormBase" ,
        tag
          str "Y74C9A.3" } } ,
    syn {
      "Y74C9A.3" ,
      "CELK05052" } ,
    locus-tag "1A478" } ,
  prot {
    name {
      "AD-003 protein (26.6 kD) (1A478)" } } ,
  rna {
    type mRNA } ,
  location {
    {
      display-str "I;-17.75 cM (interpolated genetic position)" ,
      method
        map-type cM } } ,
  gene-source {
    src "Entrez Genomes" ,
    src-int 25167480 ,
    src-str1 "NC_003279" ,
    src-str2 "CE:1A478" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      label "1A478" ,
      accession "NC_003279" ,
      version 2 ,
      seqs {
        int {
          from 4220 ,
          to 10147 ,
          strand minus ,
          id
            gi 25167480 } } ,
      products {
        {
          type mRNA ,
          accession "NM_058260" ,
          version 1 ,
          refs {
            pmid 9851916 } ,
          genomic-coords {
            mix {
              int {
                from 10094 ,
                to 10147 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 9726 ,
                to 9845 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 6036 ,
                to 6326 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 5194 ,
                to 5295 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 4220 ,
                to 4357 ,
                strand minus ,
                id
                  gi 25167480 } } } ,
          seqs {
            whole
              gi 17510630 } ,
          products {
            {
              type peptide ,
              label "AD-003 protein (26.6 kD) (1A478)" ,
              accession "NP_490660" ,
              version 1 ,
              refs {
                pmid 9851916 } ,
              genomic-coords {
                mix {
                  int {
                    from 10094 ,
                    to 10147 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 9726 ,
                    to 9845 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 6036 ,
                    to 6326 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 5194 ,
                    to 5295 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 4220 ,
                    to 4357 ,
                    strand minus ,
                    id
                      gi 25167480 } } } ,
              seqs {
                whole
                  gi 17510631 } } } ,
          comment {
            {
              type comment ,
              text "" ,
              version 0 } } } } ,
      comment {
        {
          type comment ,
          text "Title: Caenorhabditis elegans gene 1A478, AD-003 protein." ,
          version 0 } } } } ,
  comments {
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_058260" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 17510630 } ,
              anchor "NM_058260" } } ,
          seqs {
            whole
              gi 17510630 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_490660" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 17510631 } ,
                  anchor "NP_490660" } } ,
              seqs {
                whole
                  gi 17510631 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 17510631 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 24115 } ,
                          anchor "pfam05891: DUF858; Eukaryotic protein of
 unknown function (DUF858)" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 11 - 225  Blast Score: 824" ,
                          version 0 } } } } } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "AC024206" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 7105656 } ,
              anchor "AC024206" } } ,
          seqs {
            whole
              gi 7105656 } ,
          products {
            {
              type peptide ,
              accession "AAF36050" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 14550391 } ,
                  anchor "AAF36050" } } ,
              seqs {
                whole
                  gi 14550391 } } } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "Reviewed" ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 171590 } } ,
  xtra-iq {
    {
      tag "NUCLEOTIDE" ,
      value "7105656" } ,
    {
      tag "PROTEIN" ,
      value "14550391" } } ,
  non-unique-keys {
    {
      db "ID" ,
      tag
        id 25167480 } } }
Entrezgene ::= {
  track-info {
    geneid 171591 ,
    status live ,
    create-date
      std {
        year 2005 ,
        month 4 ,
        day 6 ,
        hour 18 ,
        minute 33 ,
        second 30 } ,
    update-date
      std {
        year 2005 ,
        month 1 ,
        day 18 ,
        hour 23 ,
        minute 7 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Caenorhabditis elegans" ,
      db {
        {
          db "taxon" ,
          tag
            id 6239 } } ,
      orgname {
        name
          binomial {
            genus "Caenorhabditis" ,
            species "elegans" } ,
        lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida;
 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" ,
        gcode 1 ,
        mgcode 5 ,
        div "INV" } } ,
    subtype {
      {
        subtype chromosome ,
        name "I" } } } ,
  gene {
    locus "1A489" ,
    maploc "I;-17.80 cM (interpolated genetic position)" ,
    db {
      {
        db "AceView/WormGenes" ,
        tag
          str "1A489" } ,
      {
        db "LocusID" ,
        tag
          id 171591 } ,
      {
        db "WormBase" ,
        tag
          str "Y74C9A.2" } } ,
    syn {
      "Y74C9A.2" ,
      "CELK01753" } ,
    locus-tag "1A489" } ,
  prot {
    name {
      "putative protein, with a coiled coil-4 domain (13.7 kD) (1A489)" } } ,
  rna {
    type mRNA } ,
  location {
    {
      display-str "I;-17.80 cM (interpolated genetic position)" ,
      method
        map-type cM } } ,
  gene-source {
    src "Entrez Genomes" ,
    src-int 25167480 ,
    src-str1 "NC_003279" ,
    src-str2 "CE:1A489" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      label "1A489" ,
      accession "NC_003279" ,
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      seqs {
        int {
          from 11640 ,
          to 16584 ,
          strand plus ,
          id
            gi 25167480 } } ,
      products {
        {
          type mRNA ,
          accession "NM_058259" ,
          version 1 ,
          refs {
            pmid 9851916 } ,
          genomic-coords {
            mix {
              int {
                from 11640 ,
                to 11688 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 14950 ,
                to 15159 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 16472 ,
                to 16584 ,
                strand plus ,
                id
                  gi 25167480 } } } ,
          seqs {
            whole
              gi 17510628 } ,
          products {
            {
              type peptide ,
              label "putative protein, with a coiled coil-4 domain (13.7 kD)
 (1A489)" ,
              accession "NP_490661" ,
              version 1 ,
              refs {
                pmid 9851916 ,
                pmid 11231151 } ,
              genomic-coords {
                mix {
                  int {
                    from 11640 ,
                    to 11688 ,
                    strand plus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 14950 ,
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                    strand plus ,
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                      gi 25167480 } ,
                  int {
                    from 16472 ,
                    to 16584 ,
                    strand plus ,
                    id
                      gi 25167480 } } } ,
              seqs {
                whole
                  gi 17510629 } } } ,
          comment {
            {
              type comment ,
              text "" ,
              version 0 } } } } ,
      comment {
        {
          type comment ,
          text "Title: Caenorhabditis elegans essential expressed gene 1A489." ,
          version 0 } } } } ,
  comments {
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_058259" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 17510628 } ,
              anchor "NM_058259" } } ,
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            whole
              gi 17510628 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_490661" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 17510629 } ,
                  anchor "NP_490661" } } ,
              seqs {
                whole
                  gi 17510629 } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "AC024206" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 7105656 } ,
              anchor "AC024206" } } ,
          seqs {
            whole
              gi 7105656 } ,
          products {
            {
              type peptide ,
              accession "AAF36049" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 7105658 } ,
                  anchor "AAF36049" } } ,
              seqs {
                whole
                  gi 7105658 } } } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "Reviewed" ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 171591 } } ,
  xtra-iq {
    {
      tag "NUCLEOTIDE" ,
      value "7105656" } ,
    {
      tag "PROTEIN" ,
      value "7105658" } } ,
  non-unique-keys {
    {
      db "ID" ,
      tag
        id 25167480 } } }
Entrezgene ::= {
  track-info {
    geneid 171592 ,
    status live ,
    create-date
      std {
        year 2005 ,
        month 4 ,
        day 6 ,
        hour 18 ,
        minute 31 ,
        second 55 } ,
    update-date
      std {
        year 2005 ,
        month 1 ,
        day 18 ,
        hour 23 ,
        minute 7 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Caenorhabditis elegans" ,
      db {
        {
          db "taxon" ,
          tag
            id 6239 } } ,
      orgname {
        name
          binomial {
            genus "Caenorhabditis" ,
            species "elegans" } ,
        lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida;
 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" ,
        gcode 1 ,
        mgcode 5 ,
        div "INV" } } ,
    subtype {
      {
        subtype chromosome ,
        name "I" } } } ,
  gene {
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    maploc "I;-17.86 cM (interpolated genetic position)" ,
    db {
      {
        db "AceView/WormGenes" ,
        tag
          str "1A492" } ,
      {
        db "LocusID" ,
        tag
          id 171592 } ,
      {
        db "WormBase" ,
        tag
          str "Y74C9A.4a" } } ,
    syn {
      "Y74C9A.4a" ,
      "Y74C9A.4b" ,
      "CELK08126" } ,
    locus-tag "1A492" } ,
  prot {
    name {
      "suppressor of PResenilin defect SPR-1 related; similar to co-repressor
 of REST RE1-silencing transcription factor (65.9 kD) (1A492)" ,
      "suppressor of PResenilin defect SPR-1 related; similar to co-repressor
 of REST RE1-silencing transcription factor (65.6 kD) (1A492)" } } ,
  location {
    {
      display-str "I;-17.86 cM (interpolated genetic position)" ,
      method
        map-type cM } } ,
  gene-source {
    src "Entrez Genomes" ,
    src-int 25167480 ,
    src-str1 "NC_003279" ,
    src-str2 "CE:1A492" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      label "1A492" ,
      accession "NC_003279" ,
      version 2 ,
      seqs {
        int {
          from 17910 ,
          to 26777 ,
          strand minus ,
          id
            gi 25167480 } } ,
      products {
        {
          type mRNA ,
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          refs {
            pmid 9851916 } ,
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              int {
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                strand minus ,
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              int {
                from 26589 ,
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                strand minus ,
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                strand minus ,
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                strand minus ,
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              int {
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                strand minus ,
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                strand minus ,
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              int {
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                strand minus ,
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                  gi 25167480 } ,
              int {
                from 18005 ,
                to 18114 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 17910 ,
                to 17957 ,
                strand minus ,
                id
                  gi 25167480 } } } ,
          seqs {
            whole
              gi 17510632 } ,
          products {
            {
              type peptide ,
              label "suppressor of PResenilin defect SPR-1 related; similar to
 co-repressor of REST RE1-silencing transcription factor (65.9 kD) (1A492)" ,
              accession "NP_490662" ,
              version 1 ,
              refs {
                pmid 9851916 } ,
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                mix {
                  int {
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                      gi 25167480 } ,
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                    strand minus ,
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                      gi 25167480 } ,
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
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                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 18005 ,
                    to 18114 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 17910 ,
                    to 17957 ,
                    strand minus ,
                    id
                      gi 25167480 } } } ,
              seqs {
                whole
                  gi 17510633 } } } ,
          comment {
            {
              type comment ,
              text "" ,
              version 0 } } } ,
        {
          type mRNA ,
          accession "NM_058262" ,
          version 1 ,
          refs {
            pmid 9851916 } ,
          genomic-coords {
            mix {
              int {
                from 26732 ,
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                strand minus ,
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                  gi 25167480 } ,
              int {
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              int {
                from 24928 ,
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                  gi 25167480 } ,
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              int {
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                  gi 25167480 } ,
              int {
                from 20847 ,
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                strand minus ,
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                  gi 25167480 } ,
              int {
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                strand minus ,
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                  gi 25167480 } ,
              int {
                from 19014 ,
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                strand minus ,
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                  gi 25167480 } ,
              int {
                from 18005 ,
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                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 17910 ,
                to 17957 ,
                strand minus ,
                id
                  gi 25167480 } } } ,
          seqs {
            whole
              gi 17510634 } ,
          products {
            {
              type peptide ,
              label "suppressor of PResenilin defect SPR-1 related; similar to
 co-repressor of REST RE1-silencing transcription factor (65.6 kD) (1A492)" ,
              accession "NP_490663" ,
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              refs {
                pmid 9851916 } ,
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                mix {
                  int {
                    from 26732 ,
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                      gi 25167480 } ,
                  int {
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                      gi 25167480 } ,
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                      gi 25167480 } ,
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                      gi 25167480 } ,
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                    from 24650 ,
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
                    from 21012 ,
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                      gi 25167480 } ,
                  int {
                    from 20847 ,
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
                    from 20270 ,
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
                    from 19014 ,
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
                    from 18005 ,
                    to 18114 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 17910 ,
                    to 17957 ,
                    strand minus ,
                    id
                      gi 25167480 } } } ,
              seqs {
                whole
                  gi 17510635 } } } ,
          comment {
            {
              type comment ,
              text "" ,
              version 0 } } } } ,
      comment {
        {
          type comment ,
          text "Title: Caenorhabditis elegans gene 1A492, suppressor of
 PResenilin defect SPR-1 related; similar to co-repressor of REST
 RE1-silencing transcription factor." ,
          version 0 } } } } ,
  comments {
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_058261" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 17510632 } ,
              anchor "NM_058261" } } ,
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            whole
              gi 17510632 } ,
          products {
            {
              type peptide ,
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              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 17510633 } ,
                  anchor "NP_490662" } } ,
              seqs {
                whole
                  gi 17510633 } } } } ,
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_058262" ,
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            {
              src {
                db "Nucleotide" ,
                tag
                  id 17510634 } ,
              anchor "NM_058262" } } ,
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            whole
              gi 17510634 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_490663" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 17510635 } ,
                  anchor "NP_490663" } } ,
              seqs {
                whole
                  gi 17510635 } } } } } } ,
    {
      type comment ,
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        {
          type genomic ,
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            {
              src {
                db "Nucleotide" ,
                tag
                  id 7105656 } ,
              anchor "AC024206" } } ,
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              gi 7105656 } ,
          products {
            {
              type peptide ,
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              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 14550392 } ,
                  anchor "AAK67240" } } ,
              seqs {
                whole
                  gi 14550392 } } } } ,
        {
          type genomic ,
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            {
              src {
                db "Nucleotide" ,
                tag
                  id 7105656 } ,
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            whole
              gi 7105656 } ,
          products {
            {
              type peptide ,
              accession "AAF36052" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 7105661 } ,
                  anchor "AAF36052" } } ,
              seqs {
                whole
                  gi 7105661 } } } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "Reviewed" ,
      version 0 } } ,
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    {
      db "LocusID" ,
      tag
        id 171592 } } ,
  xtra-iq {
    {
      tag "NUCLEOTIDE" ,
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    {
      tag "PROTEIN" ,
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    {
      tag "PROTEIN" ,
      value "7105661" } } ,
  non-unique-keys {
    {
      db "ID" ,
      tag
        id 25167480 } } }
Entrezgene ::= {
  track-info {
    geneid 171593 ,
    status live ,
    create-date
      std {
        year 2005 ,
        month 4 ,
        day 7 ,
        hour 13 ,
        minute 31 ,
        second 41 } ,
    update-date
      std {
        year 2005 ,
        month 1 ,
        day 18 ,
        hour 23 ,
        minute 7 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Caenorhabditis elegans" ,
      db {
        {
          db "taxon" ,
          tag
            id 6239 } } ,
      orgname {
        name
          binomial {
            genus "Caenorhabditis" ,
            species "elegans" } ,
        lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida;
 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" ,
        gcode 1 ,
        mgcode 5 ,
        div "INV" } } ,
    subtype {
      {
        subtype chromosome ,
        name "I" } } } ,
  gene {
    locus "1A502" ,
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    db {
      {
        db "AceView/WormGenes" ,
        tag
          str "1A502" } ,
      {
        db "LocusID" ,
        tag
          id 171593 } ,
      {
        db "WormBase" ,
        tag
          str "Y74C9A.5" } } ,
    syn {
      "Y74C9A.5" ,
      "CELK09643" } ,
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  prot {
    name {
      "sestrin (1A502)" } } ,
  rna {
    type mRNA } ,
  location {
    {
      display-str "I;-17.91 cM (interpolated genetic position)" ,
      method
        map-type cM } } ,
  gene-source {
    src "Entrez Genomes" ,
    src-int 25167480 ,
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    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      label "1A502" ,
      accession "NC_003279" ,
      version 2 ,
      seqs {
        int {
          from 28279 ,
          to 34904 ,
          strand minus ,
          id
            gi 25167480 } } ,
      products {
        {
          type mRNA ,
          accession "NM_058263" ,
          version 1 ,
          refs {
            pmid 9851916 } ,
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              int {
                from 34694 ,
                to 34904 ,
                strand minus ,
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                  gi 25167480 } ,
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                from 32598 ,
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                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 32411 ,
                to 32541 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 31768 ,
                to 32071 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 29768 ,
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                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 29099 ,
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                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 28915 ,
                to 29025 ,
                strand minus ,
                id
                  gi 25167480 } ,
              int {
                from 28279 ,
                to 28404 ,
                strand minus ,
                id
                  gi 25167480 } } } ,
          seqs {
            whole
              gi 17510636 } ,
          products {
            {
              type peptide ,
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              version 1 ,
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                pmid 9851916 } ,
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                    from 34694 ,
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                      gi 25167480 } ,
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                    from 32598 ,
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                      gi 25167480 } ,
                  int {
                    from 32411 ,
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
                    from 31768 ,
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                    strand minus ,
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                      gi 25167480 } ,
                  int {
                    from 29768 ,
                    to 30423 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 29099 ,
                    to 29366 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 28915 ,
                    to 29025 ,
                    strand minus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 28279 ,
                    to 28404 ,
                    strand minus ,
                    id
                      gi 25167480 } } } ,
              seqs {
                whole
                  gi 17510637 } } } ,
          comment {
            {
              type comment ,
              text "" ,
              version 0 } } } } ,
      comment {
        {
          type comment ,
          text "Title: Caenorhabditis elegans gene 1A502, sestrin." ,
          version 0 } } } } ,
  comments {
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_058263" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 17510636 } ,
              anchor "NM_058263" } } ,
          seqs {
            whole
              gi 17510636 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_490664" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 17510637 } ,
                  anchor "NP_490664" } } ,
              seqs {
                whole
                  gi 17510637 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 17510637 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 15933 } ,
                          anchor "pfam04636: PA26; PA26 p53-induced protein
 (sestrin)" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 88 - 644  Blast Score: 1457" ,
                          version 0 } } } } } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "AC024206" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 7105656 } ,
              anchor "AC024206" } } ,
          seqs {
            whole
              gi 7105656 } ,
          products {
            {
              type peptide ,
              accession "AAF36051" ,
              version 1 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 7105660 } ,
                  anchor "AAF36051" } } ,
              seqs {
                whole
                  gi 7105660 } } } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "Reviewed" ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 171593 } } ,
  xtra-iq {
    {
      tag "NUCLEOTIDE" ,
      value "7105656" } ,
    {
      tag "PROTEIN" ,
      value "7105660" } } ,
  non-unique-keys {
    {
      db "ID" ,
      tag
        id 25167480 } } }
Entrezgene ::= {
  track-info {
    geneid 171594 ,
    status live ,
    create-date
      std {
        year 2005 ,
        month 4 ,
        day 7 ,
        hour 13 ,
        minute 31 ,
        second 47 } ,
    update-date
      std {
        year 2005 ,
        month 1 ,
        day 18 ,
        hour 23 ,
        minute 7 ,
        second 0 } } ,
  type protein-coding ,
  source {
    genome genomic ,
    origin natural ,
    org {
      taxname "Caenorhabditis elegans" ,
      db {
        {
          db "taxon" ,
          tag
            id 6239 } } ,
      orgname {
        name
          binomial {
            genus "Caenorhabditis" ,
            species "elegans" } ,
        lineage "Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida;
 Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis" ,
        gcode 1 ,
        mgcode 5 ,
        div "INV" } } ,
    subtype {
      {
        subtype chromosome ,
        name "I" } } } ,
  gene {
    locus "1A527" ,
    maploc "I;-18.07 cM (interpolated genetic position)" ,
    db {
      {
        db "AceView/WormGenes" ,
        tag
          str "1A527" } ,
      {
        db "LocusID" ,
        tag
          id 171594 } ,
      {
        db "WormBase" ,
        tag
          str "Y48G1C.4" } } ,
    syn {
      "Y48G1C.4" ,
      "CELK05819" } ,
    locus-tag "1A527" } ,
  prot {
    name {
      "putative phosphatidylglycerophosphate synthase, similar to
 silencer-associated factor (51.7 kD) (1A527)" } } ,
  rna {
    type mRNA } ,
  location {
    {
      display-str "I;-18.07 cM (interpolated genetic position)" ,
      method
        map-type cM } } ,
  gene-source {
    src "Entrez Genomes" ,
    src-int 25167480 ,
    src-str1 "NC_003279" ,
    src-str2 "CE:1A527" ,
    gene-display FALSE ,
    locus-display FALSE ,
    extra-terms FALSE } ,
  locus {
    {
      type genomic ,
      label "1A527" ,
      accession "NC_003279" ,
      version 2 ,
      seqs {
        int {
          from 49920 ,
          to 54359 ,
          strand plus ,
          id
            gi 25167480 } } ,
      products {
        {
          type mRNA ,
          accession "NM_058265" ,
          version 2 ,
          refs {
            pmid 9851916 } ,
          genomic-coords {
            mix {
              int {
                from 49920 ,
                to 50015 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 50814 ,
                to 51029 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 52282 ,
                to 52409 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 52465 ,
                to 52571 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 53265 ,
                to 53336 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 53390 ,
                to 53694 ,
                strand plus ,
                id
                  gi 25167480 } ,
              int {
                from 53943 ,
                to 54359 ,
                strand plus ,
                id
                  gi 25167480 } } } ,
          seqs {
            whole
              gi 25143330 } ,
          products {
            {
              type peptide ,
              label "putative phosphatidylglycerophosphate synthase, similar
 to silencer-associated factor (51.7 kD) (1A527)" ,
              accession "NP_490666" ,
              version 2 ,
              refs {
                pmid 9851916 ,
                pmid 11231151 } ,
              genomic-coords {
                mix {
                  int {
                    from 49920 ,
                    to 50015 ,
                    strand plus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 50814 ,
                    to 51029 ,
                    strand plus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 52282 ,
                    to 52409 ,
                    strand plus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 52465 ,
                    to 52571 ,
                    strand plus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 53265 ,
                    to 53336 ,
                    strand plus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 53390 ,
                    to 53694 ,
                    strand plus ,
                    id
                      gi 25167480 } ,
                  int {
                    from 53943 ,
                    to 54359 ,
                    strand plus ,
                    id
                      gi 25167480 } } } ,
              seqs {
                whole
                  gi 25143331 } } } ,
          comment {
            {
              type comment ,
              text "" ,
              version 0 } } } } ,
      comment {
        {
          type comment ,
          text "Title: Caenorhabditis elegans essential gene 1A527, putative
 phosphatidylglycerophosphate synthase, similar to silencer-associated factor." ,
          version 0 } } } } ,
  comments {
    {
      type comment ,
      heading "NCBI Reference Sequences (RefSeq)" ,
      version 0 ,
      products {
        {
          type mRNA ,
          heading "mRNA Sequence" ,
          accession "NM_058265" ,
          version 2 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 25143330 } ,
              anchor "NM_058265" } } ,
          seqs {
            whole
              gi 25143330 } ,
          products {
            {
              type peptide ,
              heading "Product" ,
              accession "NP_490666" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 25143331 } ,
                  anchor "NP_490666" } } ,
              seqs {
                whole
                  gi 25143331 } ,
              comment {
                {
                  type other ,
                  heading "Conserved Domains" ,
                  version 0 ,
                  source {
                    {
                      src {
                        db "PROT_CDD" ,
                        tag
                          id 25143331 } ,
                      pre-text "(1)" ,
                      anchor "summary" } } ,
                  comment {
                    {
                      type other ,
                      version 0 ,
                      source {
                        {
                          src {
                            db "CDD" ,
                            tag
                              id 5372 } ,
                          anchor "cd00138: PLDc; Phospholipase D" } } ,
                      comment {
                        {
                          type other ,
                          text "Location: 20 - 172  Blast Score: 135" ,
                          version 0 } } } } } } } } } } } ,
    {
      type comment ,
      heading "Related Sequences" ,
      version 0 ,
      products {
        {
          type genomic ,
          heading "Genomic" ,
          accession "AC024796" ,
          version 1 ,
          source {
            {
              src {
                db "Nucleotide" ,
                tag
                  id 7140352 } ,
              anchor "AC024796" } } ,
          seqs {
            whole
              gi 7140352 } ,
          products {
            {
              type peptide ,
              accession "AAK29892" ,
              version 2 ,
              source {
                {
                  src {
                    db "Protein" ,
                    tag
                      id 16950493 } ,
                  anchor "AAK29892" } } ,
              seqs {
                whole
                  gi 16950493 } } } } } } ,
    {
      type comment ,
      heading "RefSeq Status" ,
      label "Reviewed" ,
      version 0 } } ,
  unique-keys {
    {
      db "LocusID" ,
      tag
        id 171594 } } ,
  xtra-iq {
    {
      tag "NUCLEOTIDE" ,
      value "7140352" } ,
    {
      tag "PROTEIN" ,
      value "16950493" } } ,
  non-unique-keys {
    {
      db "ID" ,
      tag
        id 25167480 } } }
