BLASTP 2.0MP-WashU [04-May-2006] [linux26-x64-I32LPF64 2006-05-10T17:22:28]

Copyright (C) 1996-2006 Washington University, Saint Louis, Missouri USA.
All Rights Reserved.

Reference:  Gish, W. (1996-2006) http://blast.wustl.edu

Query=  Celegans_dcr1
        (1845 letters)

Database:  swissprot
           353,658 sequences; 132,868,552 total letters.
Searching....10....20....30....40....50....60....70....80....90....100% done

                                                                     Smallest
                                                                       Sum
                                                              High  Probability
Sequences producing High-scoring Segment Pairs:              Score  P(N)      N

sp|P34529.2|DCR1_CAEEL RecName: Full=Endoribonuclease dcr-1   9560  0.        1
sp|Q9VCU9.1|DCR1_DROME RecName: Full=Endoribonuclease Dcr...  1792  1.5e-232  3
sp|Q9UPY3.2|DICER_HUMAN RecName: Full=Endoribonuclease Di...  2152  6.4e-223  1
sp|Q8R418.2|DICER_MOUSE RecName: Full=Endoribonuclease Di...  2120  1.6e-219  1
sp|P84634.1|DCL4_ARATH RecName: Full=Dicer-like protein 4      471  8.6e-72   5
sp|Q7S8J7.1|DCL1_NEUCR RecName: Full=Dicer-like protein 1...   505  3.0e-69   6
sp|A4RKC3.2|DCL1_MAGGR RecName: Full=Dicer-like protein 1...   481  3.5e-69   6
sp|Q0CW42.2|DCL1_ASPTN RecName: Full=Dicer-like protein 1...   464  4.8e-65   6
sp|Q1DKI1.2|DCL1_COCIM RecName: Full=Dicer-like protein 1...   498  8.4e-64   6
sp|A2RAF3.2|DCL1_ASPNC RecName: Full=Dicer-like protein 1...   466  5.3e-62   5
sp|Q09884.1|DCR1_SCHPO RecName: Full=Protein Dicer; AltNa...   415  7.7e-61   4
sp|A1CBC9.2|DCL1_ASPCL RecName: Full=Dicer-like protein 1...   428  1.2e-60   6
sp|A1DE13.1|DCL1_NEOFI RecName: Full=Dicer-like protein 1...   457  1.6e-60   6
sp|Q2VF19.1|DCL1_CRYPA RecName: Full=Dicer-like protein 1...   465  4.2e-60   4
sp|Q0UI93.2|DCL1_PHANO RecName: Full=Dicer-like protein 1...   490  3.8e-59   5
sp|Q4WVE3.3|DCL1_ASPFU RecName: Full=Dicer-like protein 1...   466  4.8e-59   6
sp|Q2U6C4.2|DCL1_ASPOR RecName: Full=Dicer-like protein 1...   474  8.5e-58   4
sp|Q2UNX5.1|DCL2_ASPOR RecName: Full=Dicer-like protein 2...   396  1.0e-53   5
sp|Q4WA22.2|DCL2_ASPFU RecName: Full=Dicer-like protein 2...   369  1.7e-51   5


>sp|P34529.2|DCR1_CAEEL RecName: Full=Endoribonuclease dcr-1
        Length = 1845

 Score = 9560 (3370.3 bits), Expect = 0., P = 0.
 Identities = 1845/1845 (100%), Positives = 1845/1845 (100%)
 Links = (1)

Query:     1 MVRVRADLQCFNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQ 60
             MVRVRADLQCFNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQ
Sbjct:     1 MVRVRADLQCFNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQ 60

Query:    61 GGKRAFFVVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVI 120
             GGKRAFFVVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVI
Sbjct:    61 GGKRAFFVVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVI 120

Query:   121 TAQCLLDLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLT 180
             TAQCLLDLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLT
Sbjct:   121 TAQCLLDLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLT 180

Query:   181 ASLIKAKVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLG 240
             ASLIKAKVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLG
Sbjct:   181 ASLIKAKVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLG 240

Query:   241 IPNFDTVIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQ 300
             IPNFDTVIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQ
Sbjct:   241 IPNFDTVIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQ 300

Query:   301 VWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIR 360
             VWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIR
Sbjct:   301 VWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIR 360

Query:   361 LFEILETFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPD 420
             LFEILETFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPD
Sbjct:   361 LFEILETFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPD 420

Query:   421 YVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR 480
             YVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR
Sbjct:   421 YVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR 480

Query:   481 PLDMRSYVQSKGRARRAGSRYVITVEEKDTAAYCSKLPSDIFTRLVPHNQIIPIEENGVT 540
             PLDMRSYVQSKGRARRAGSRYVITVEEKDTAAYCSKLPSDIFTRLVPHNQIIPIEENGVT
Sbjct:   481 PLDMRSYVQSKGRARRAGSRYVITVEEKDTAAYCSKLPSDIFTRLVPHNQIIPIEENGVT 540

Query:   541 KYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRESI 600
             KYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRESI
Sbjct:   541 KYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRESI 600

Query:   601 AKLLEHIDEEPDEYAPGIAAKVGSSKRKQLYDKKIARALNESFVEADKECFIYAFELERF 660
             AKLLEHIDEEPDEYAPGIAAKVGSSKRKQLYDKKIARALNESFVEADKECFIYAFELERF
Sbjct:   601 AKLLEHIDEEPDEYAPGIAAKVGSSKRKQLYDKKIARALNESFVEADKECFIYAFELERF 660

Query:   661 REAELTLNPKRRKFEDPFNYEYCFGFLSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTV 720
             REAELTLNPKRRKFEDPFNYEYCFGFLSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTV
Sbjct:   661 REAELTLNPKRRKFEDPFNYEYCFGFLSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTV 720

Query:   721 TAAQLQEIQLFHNYLFTQVLQMCKTGNLEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKY 780
             TAAQLQEIQLFHNYLFTQVLQMCKTGNLEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKY
Sbjct:   721 TAAQLQEIQLFHNYLFTQVLQMCKTGNLEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKY 780

Query:   781 VSEVVANMENMPRIPKDEVRRQYKFNAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPS 840
             VSEVVANMENMPRIPKDEVRRQYKFNAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPS
Sbjct:   781 VSEVVANMENMPRIPKDEVRRQYKFNAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPS 840

Query:   841 SKFPDTHFETFNEYFIKKYKLEIYDQNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVSNS 900
             SKFPDTHFETFNEYFIKKYKLEIYDQNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVSNS
Sbjct:   841 SKFPDTHFETFNEYFIKKYKLEIYDQNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVSNS 900

Query:   901 STSNIPQASASDSKESNTSVPHSSQRQILVPELMDIHPISATLWNVIAALPSIFYRVNQL 960
             STSNIPQASASDSKESNTSVPHSSQRQILVPELMDIHPISATLWNVIAALPSIFYRVNQL
Sbjct:   901 STSNIPQASASDSKESNTSVPHSSQRQILVPELMDIHPISATLWNVIAALPSIFYRVNQL 960

Query:   961 LLTDELRETILVKAFGKEKTKLDDNVEWNSLAYATEYEEKQTIIVKKIQQLRDLNQKSIE 1020
             LLTDELRETILVKAFGKEKTKLDDNVEWNSLAYATEYEEKQTIIVKKIQQLRDLNQKSIE
Sbjct:   961 LLTDELRETILVKAFGKEKTKLDDNVEWNSLAYATEYEEKQTIIVKKIQQLRDLNQKSIE 1020

Query:  1021 DQERETRENDKIDDGEELFNIGVWDPEEAVRIGVEISSRDDRMDGEDQDTVGLTQGLHDG 1080
             DQERETRENDKIDDGEELFNIGVWDPEEAVRIGVEISSRDDRMDGEDQDTVGLTQGLHDG
Sbjct:  1021 DQERETRENDKIDDGEELFNIGVWDPEEAVRIGVEISSRDDRMDGEDQDTVGLTQGLHDG 1080

Query:  1081 NISDEDDELPFVMHDYTARLTSNRNGIGAWSGSESIVPSGWGDWDGPEPDNSPMPFQILG 1140
             NISDEDDELPFVMHDYTARLTSNRNGIGAWSGSESIVPSGWGDWDGPEPDNSPMPFQILG
Sbjct:  1081 NISDEDDELPFVMHDYTARLTSNRNGIGAWSGSESIVPSGWGDWDGPEPDNSPMPFQILG 1140

Query:  1141 GPGGLNVQALMADVGRVFDPSTASSSLSQTVQESTVSPPKQLTKEEEQFKKLQNDLLKQA 1200
             GPGGLNVQALMADVGRVFDPSTASSSLSQTVQESTVSPPKQLTKEEEQFKKLQNDLLKQA
Sbjct:  1141 GPGGLNVQALMADVGRVFDPSTASSSLSQTVQESTVSPPKQLTKEEEQFKKLQNDLLKQA 1200

Query:  1201 KERLEALEMSEDMEKPRRLEDTVNLEDYGDDQENQEDENTPTNFPKTIDEEIEELSIGAR 1260
             KERLEALEMSEDMEKPRRLEDTVNLEDYGDDQENQEDENTPTNFPKTIDEEIEELSIGAR
Sbjct:  1201 KERLEALEMSEDMEKPRRLEDTVNLEDYGDDQENQEDENTPTNFPKTIDEEIEELSIGAR 1260

Query:  1261 KKQEIDDNAAKTDVLERENCEVLPVAINEKSRSFSFEKESKAINGRLIRQRSEEYVSHID 1320
             KKQEIDDNAAKTDVLERENCEVLPVAINEKSRSFSFEKESKAINGRLIRQRSEEYVSHID
Sbjct:  1261 KKQEIDDNAAKTDVLERENCEVLPVAINEKSRSFSFEKESKAINGRLIRQRSEEYVSHID 1320

Query:  1321 SDIGLGVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSF 1380
             SDIGLGVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSF
Sbjct:  1321 SDIGLGVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSF 1380

Query:  1381 ARSKEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPPCYIPTCDFKAPNTDDAEEKDNE 1440
             ARSKEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPPCYIPTCDFKAPNTDDAEEKDNE
Sbjct:  1381 ARSKEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPPCYIPTCDFKAPNTDDAEEKDNE 1440

Query:  1441 IERILDGQVIEEKPENKTGWDIGGDVSKSTTDGIETITFPKQARVGNDDISPLPYNLLTQ 1500
             IERILDGQVIEEKPENKTGWDIGGDVSKSTTDGIETITFPKQARVGNDDISPLPYNLLTQ
Sbjct:  1441 IERILDGQVIEEKPENKTGWDIGGDVSKSTTDGIETITFPKQARVGNDDISPLPYNLLTQ 1500

Query:  1501 QHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRFIDTPT 1560
             QHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRFIDTPT
Sbjct:  1501 QHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRFIDTPT 1560

Query:  1561 NPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLG 1620
             NPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLG
Sbjct:  1561 NPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLG 1620

Query:  1621 DAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHM 1680
             DAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHM
Sbjct:  1621 DAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHM 1680

Query:  1681 IEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDSG 1740
             IEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDSG
Sbjct:  1681 IEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDSG 1740

Query:  1741 RNLDTTWQVIFHMMRGTIELCCANPPRSPIRELMEFEQSKVRFSKMERILESGKVRVTVE 1800
             RNLDTTWQVIFHMMRGTIELCCANPPRSPIRELMEFEQSKVRFSKMERILESGKVRVTVE
Sbjct:  1741 RNLDTTWQVIFHMMRGTIELCCANPPRSPIRELMEFEQSKVRFSKMERILESGKVRVTVE 1800

Query:  1801 VVNNMRFTGMGRNYRIAKATAAKRALKYLHQIEQQRRQSPSLTTV 1845
             VVNNMRFTGMGRNYRIAKATAAKRALKYLHQIEQQRRQSPSLTTV
Sbjct:  1801 VVNNMRFTGMGRNYRIAKATAAKRALKYLHQIEQQRRQSPSLTTV 1845


>sp|Q9VCU9.1|DCR1_DROME RecName: Full=Endoribonuclease Dcr-1; Short=Protein
            dicer-1
        Length = 2249

 Score = 1792 (635.9 bits), Expect = 1.5e-232, Sum P(3) = 1.5e-232
 Identities = 522/1454 (35%), Positives = 748/1454 (51%)
 Links = 2-3-(1)

Query:   513 YCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQM 572
             YC++LPSD FT+L    +    E  GVT +   L LPINSP+KH IV   PMP +  A+ 
Sbjct:   832 YCARLPSDTFTKLTALWRCTRNERAGVTLFQYTLRLPINSPLKHDIV-GLPMPTQTLARR 890

Query:   573 AVALEACRQLHLEGELDDNLLPKGRESIAKL---LEHIDEEP-DEYAPGIA--AKVGSSK 626
               AL+AC +LH  GELDD L P G+E    L    E  + EP DE    ++   + G++K
Sbjct:   891 LAALQACVELHRIGELDDQLQPIGKEGFRALEPDWECFELEPEDEQIVQLSDEPRPGTTK 950

Query:   627 RKQLYDKKIARALNESFVEADKECFIYAFELERFREAELTLNPKRRKFEDPFNYEYCFGF 686
             R+Q Y K+IA    +    A   C++Y  +L          N + RK   P + +  FG 
Sbjct:   951 RRQYYYKRIASEFCDCRPVAGAPCYLYFIQLTLQCPIPEEQNTRGRKIYPPEDAQQGFGI 1010

Query:   687 LSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTVTAAQLQEIQLFHNYLFTQVLQMCKTG 746
             L+ K IPK+  F +F R G +KV L +A ++  +T+ Q+  I  F NY FT VL++ K  
Sbjct:  1011 LTTKRIPKLSAFSIFTRSGEVKVSLELAKERVILTSEQIVCINGFLNYTFTNVLRLQKFL 1070

Query:   747 NL-EFDGTSNAPLNTLIVPLNKRKDDMSYTINMKYVSEVVANMENMPRIPKDEVRRQYKF 805
              L + D T N      IVP  K      + I+ +++  + AN   MPR   DE R+   F
Sbjct:  1071 MLFDPDSTENC---VFIVPTVKAPAGGKH-IDWQFLELIQANGNTMPRAVPDEERQAQPF 1126

Query:   806 NAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPSSKFPDTHFETFNEYFIKKYKLEIYD 865
             + + ++DA+VMPWYRN +QP ++YVAEI P   P S FP  ++ TF  Y++ KY L I +
Sbjct:  1127 DPQRFQDAVVMPWYRNQDQPQYFYVAEICPHLSPLSCFPGDNYRTFKHYYLVKYGLTIQN 1186

Query:   866 QNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVSNSSTSNIPQASASDSKESNTSVPHSSQ 925
              +Q LLDVD TS RLN L PR  N+   +   S+  T          +K  N       Q
Sbjct:  1187 TSQPLLDVDHTSARLNFLTPRYVNRKGVALPTSSEETKR--------AKRENLE-----Q 1233

Query:   926 RQILVPELMDIHPISATLWNVIAALPSIFYRVNQLLLTDELRETILVK-AFGKEKTKLDD 984
             +QILVPEL  +HP  A+LW     LP I YR+N LLL D++R+ +      G+++ + D+
Sbjct:  1234 KQILVPELCTVHPFPASLWRTAVCLPCILYRINGLLLADDIRKQVSADLGLGRQQIE-DE 1292

Query:   985 NVEWNSLAYATEYEE--KQTIIVKKIQQLRD--LNQKSIEDQERE-TRENDKID-DGEEL 1038
             + EW  L +     E  K++   K+ + L+D  +N K + D E++ T E  ++D D ++ 
Sbjct:  1293 DFEWPMLDFGWSLSEVLKKSRESKQKESLKDDTINGKDLADVEKKPTSEETQLDKDSKD- 1351

Query:  1039 FNIGVWDPEEAVRIGVEISSRDDRMDGEDQDTVGL-TQGLHDGNIS------DEDD--EL 1089
                   D  E   I + I   +   + +D   +G  +  + D   S      DEDD   L
Sbjct:  1352 ------DKVEKSAIELIIEGEEKLQEADDFIEIGTWSNDMADDIASFNQEDDDEDDAFHL 1405

Query:  1090 PFV-----MHDYTARLTSNR-----NGIGAWSGSESIV--PSGWGDWDGP-EP------- 1129
             P +       D   R  S       NG   + G +S      G G   GP +P       
Sbjct:  1406 PVLPANVKFCDQQTRYGSPTFWDVSNGESGFKGPKSSQNKQGGKGKAKGPAKPTFNYYDS 1465

Query:  1130 DNS-PMPFQILGGPGGLNVQA--LMADVGRVFDPSTASSSLSQTVQES-TVSPPKQLTKE 1185
             DNS    +      G LN       +D   V D   A      +  E+ T+   +++ K 
Sbjct:  1466 DNSLGSSYDDDDNAGPLNYMHHNYSSDDDDVADDIDAGRIAFTSKNEAETIETAQEVEKR 1525

Query:  1186 EEQFKKLQ----NDL-LKQAKERLEALEMS-EDMEKPR--RLEDTV-----NLEDYG--- 1229
             ++Q   +Q    N+   +Q K  L       ED ++P   R E+++      +E  G   
Sbjct:  1526 QKQLSIIQATNANERQYQQTKNLLIGFNFKHEDQKEPATIRYEESIAKLKTEIESGGMLV 1585

Query:  1230 -DDQEN--QEDENTPTNFPKT------------IDEEIEELSIGARKKQEIDD----NAA 1270
               DQ+   +  +       K             ++E++    +G R++  + D    NA 
Sbjct:  1586 PHDQQLVLKRSDAAEAQVAKVSMMELLKQLLPYVNEDVLAKKLGDRRELLLSDLVELNAD 1645

Query:  1271 KTDVLERENCEVLPVA-------------INEKSRSFSFEK-------ESKAINGRLIR- 1309
                  E+E   V+                ++EK     +E+        +KAI   ++  
Sbjct:  1646 WVARHEQETYNVMGCGDSFDNYNDHHRLNLDEKQLKLQYERIEIEPPTSTKAITSAILPA 1705

Query:  1310 ----QRSEEYVSHIDSDIGLGVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDY 1365
                  R  + V H       G SP ++L ALT SNA DG++LER ETIGDSFLK+A T Y
Sbjct:  1706 GFSFDRQPDLVGHP------GPSPSIILQALTMSNANDGINLERLETIGDSFLKYAITTY 1759

Query:  1366 LYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPPCY-IPT- 1423
             LY T  + HEGKLS  RSK+V+N NLYRLG++  + + ++A KF+ HD+WLPPCY +P  
Sbjct:  1760 LYITYENVHEGKLSHLRSKQVANLNLYRLGRRKRLGEYMIATKFEPHDNWLPPCYYVPKE 1819

Query:  1424 -----CDFKAPNTDDAEEKDN-EIERILDGQVIEEKPE--NKTGWDIGGDVSKSTTDGIE 1475
                   + K P T   +  D  +I+ +   Q+ E   E  +  G +  G       D   
Sbjct:  1820 LEKALIEAKIP-THHWKLADLLDIKNLSSVQICEMVREKADALGLEQNGGAQNGQLDDSN 1878

Query:  1476 TITFPKQARVGNDDISPLPYNLLTQQHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWM 1535
                        ND    +PYNL++Q  I DKSIAD VEALIG +L+  GP   L  M W+
Sbjct:  1879 DSC--------NDFSCFIPYNLVSQHSIPDKSIADCVEALIGAYLIECGPRGALLFMAWL 1930

Query:  1536 GLKVI----QKD---QKSDVPS---PLLRFIDT-----PTNPNASLNFLNNLWQQFQ--- 1577
             G++V+    Q D   Q+  +P    P    + T     PT  +  L+F  N  ++     
Sbjct:  1931 GVRVLPITRQLDGGNQEQRIPGSTKPNAENVVTVYGAWPTPRSPLLHFAPNATEELDQLL 1990

Query:  1578 --FTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLGDAVLDYMITRYLFED 1635
               F + EE +GY+F++R+YL+QA THASY  NR+T CYQRLEFLGDAVLDY+ITR+L+ED
Sbjct:  1991 SGFEEFEESLGYKFRDRSYLLQAMTHASYTPNRLTDCYQRLEFLGDAVLDYLITRHLYED 2050

Query:  1636 SRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHMIEKFVKLCSERNFDT 1695
              RQ+SPG LTDLRSALVNNTIFASLAV+  F K F  + PGL  +I++FV++  E     
Sbjct:  2051 PRQHSPGALTDLRSALVNNTIFASLAVRHGFHKFFRHLSPGLNDVIDRFVRIQQENG--- 2107

Query:  1696 NFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDSGRNLDTTWQVIFHMMR 1755
             +  +E Y + +EEE D+   ED+EVPKA+GD+FES+AGAI+LDS  +LD  W V  +MM 
Sbjct:  2108 HCISEEYYLLSEEECDDA--EDVEVPKALGDVFESIAGAIFLDSNMSLDVVWHVYSNMMS 2165

Query:  1756 GTIELCCANPPRSPIRELMEFEQSKVRFSKMERILESGKVRVTVEVVNNMRFTGMGRNYR 1815
               IE    + P+SPIREL+E E    +F K E++ +  +VRVTV+V     F G+GRNYR
Sbjct:  2166 PEIEQFSNSVPKSPIRELLELEPETAKFGKPEKLADGRRVRVTVDVFCKGTFRGIGRNYR 2225

Query:  1816 IAKATAAKRALKYL 1829
             IAK TAAK AL+ L
Sbjct:  2226 IAKCTAAKCALRQL 2239

 Score = 253 (94.1 bits), Expect = 1.5e-232, Sum P(3) = 1.5e-232
 Identities = 95/376 (25%), Positives = 169/376 (44%)
 Links = (2)-3-1

Query:    11 FNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKRAFFVVE 70
             F PRD+QVELL  A ++NTI+ LG  S K FIA+ LL+E   +       G    +   E
Sbjct:    15 FTPRDFQVELLATAYERNTIICLGHRSSKEFIALKLLQELSRRARR---HGRVSVYLSCE 71

Query:    71 KVNLVEQQAIHIEV-H-TSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDL 128
                  E  +I+  + H T  +V Q          D +   D     +HV ++  +  L L
Sbjct:    72 VGTSTEPCSIYTMLTHLTDLRVWQEQP-------DMQIPFDHCWTDYHVSILRPEGFLYL 124

Query:   129 IRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAKV 188
             +    L +  + +++ ++CH +   Q   R +  ++ +       PR+LGL   L  A  
Sbjct:   125 LETRELLLSSVELIVLEDCHDSAVYQR-IRPLFENHIMPAPPADRPRILGLAGPLHSAGC 183

Query:   189 APEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVI 248
               ++L   L  LE ++   IETASD+V++ +Y ++P+E ++ C  FE+  L +   D + 
Sbjct:   184 ELQQLSAMLATLEQSVLCQIETASDIVTVLRYCSRPHEYIVQCAPFEMDELSLVLADVLN 243

Query:   249 E----IFDETVA--FVNTTTEFHPDL-DL-DPRRPIKDSLKTTRAVFRQLGPWAAWRTAQ 300
                  + D       +  T +F  +L D+ DP+    + + +   V  ++GPW   R A 
Sbjct:   244 THKSFLLDHRYDPYEIYGTDQFMDELKDIPDPKVDPLNVINSLLVVLHEMGPWCTQRAAH 303

Query:   301 VWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKK-----IKSIEALRPYVP 355
              +  +  + +K +   ++      +  T++I +  L E    +       S + +  Y  
Sbjct:   304 HFY-QCNEKLKVKTPHERHYLLYCLVSTALIQLYSLCEHAFHRHLGSGSDSRQTIERYSS 362

Query:   356 QRVIRLFEILETFNPE 371
              +V RL + L  F PE
Sbjct:   363 PKVRRLLQTLRCFKPE 378

 Score = 238 (88.8 bits), Expect = 1.5e-232, Sum P(3) = 1.5e-232
 Identities = 51/125 (40%), Positives = 76/125 (60%)
 Links = 2-(3)-1

Query:   382 AEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYVVG-ASGRNLASSDSQGLHK 440
             ++ L A+I+ +Q + A  L  ++  I   +P  KF+   Y     +       +++  H+
Sbjct:   490 SDTLCALIYCNQNHTARVLFELLAEISRRDPDLKFLRCQYTTDRVADPTTEPKEAELEHR 549

Query:   441 RQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPLDMRSYVQSKGRARRAGSR 500
             RQ EVL+RF  ++ N LI TSVLEEG+DV +CNLV+++D P   RSYVQ KGRAR A + 
Sbjct:   550 RQEEVLKRFRMHDCNVLIGTSVLEEGIDVPKCNLVVRWDPPTTYRSYVQCKGRARAAPAY 609

Query:   501 YVITV 505
             +VI V
Sbjct:   610 HVILV 614

 Score = 44 (20.5 bits), Expect = 4.4e-212, Sum P(3) = 4.4e-212
 Identities = 10/34 (29%), Positives = 17/34 (50%)
 Links = 2-(4)-1

Query:   580 RQLHLEGELDDNLLPKGRESIAKLLEHIDEEPDE 613
             R  H   + D N L    ES  ++++ +D+ P E
Sbjct:   389 RMRHQVDQADFNRLSHTLESKCRMVDQMDQPPTE 422


>sp|Q9UPY3.2|DICER_HUMAN RecName: Full=Endoribonuclease Dicer; AltName:
            Full=Helicase with RNase motif; Short=Helicase MOI
        Length = 1912

 Score = 2152 (762.6 bits), Expect = 6.4e-223, P = 6.4e-223
 Identities = 706/2058 (34%), Positives = 1011/2058 (49%)
 Links = (1)

Query:    11 FNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKRAFFVVE 70
             + PR YQVELL+ A   NTIV L TGSGKTFIAVLL KE   Q+     + GKR  F+V 
Sbjct:    32 YTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVN 91

Query:    71 KVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLIR 130
               N V QQ   +  H+  KVG+      +  W +KE+ +Q   +H V+++T    L++++
Sbjct:    92 SANQVAQQVSAVRTHSDLKVGEYSNLEVNASW-TKERWNQEFTKHQVLIMTCYVALNVLK 150

Query:   131 HAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAKVAP 190
             + YL + D+ +L+FDECH A+   HPYR IM   KL +     PR+LGLTAS++  K  P
Sbjct:   151 NGYLSLSDINLLVFDECHLAI-LDHPYREIM---KLCENCPSCPRILGLTASILNGKCDP 206

Query:   191 EKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVIEI 250
             E+L E+++KLE  + S  ETA+DLV L +Y ++P E+V+ C  F     G+  ++ ++  
Sbjct:   207 EELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDRS-GL--YERLLME 263

Query:   251 FDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELGKII 310
              +E + F+N         + D     K  L   RAV   LGPW A + A +  +EL K I
Sbjct:   264 LEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYI 323

Query:   311 KSQVLPDKTLRFLNMAKTSMITIKRLLEPEM------------KKIKSIEALRPYVPQRV 358
             K +   +   +FL    T +  I  L E               K IK +E LR Y P   
Sbjct:   324 KHEQ-EELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILRKYKPYER 382

Query:   359 IRLFEILETFN------------PEFQKERMKLEKAEH------------LSAIIFVDQR 394
              + FE +E +N             E   E  ++E+ E             L  IIFV++R
Sbjct:   383 -QQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTNILCGIIFVERR 441

Query:   395 YIAYSLLLMMRHIKSWEPKFKFVNPDYVVGAS-GRNLA-SSDSQGLHKRQTEVLRRFHRN 452
             Y A  L  +++     +P+  +++ +++ G   G+N   +   +   ++Q EVLR+F  +
Sbjct:   442 YTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAH 501

Query:   453 EINCLIATSVLEEGVDVKQCNLVIKFDRPLDMRSYVQSKGRARRAGSRYVITVE------ 506
             E N LIATS++EEGVD+ +CNLV++FD P + RSYVQSKGRAR   S Y++  +      
Sbjct:   502 ETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLADTDKIKS 561

Query:   507 -EKD-----------------------------------------------------TAA 512
              E+D                                                     TA 
Sbjct:   562 FEEDLKTYKAIEKILRNKCSKSVDTGETDIDPVMDDDDVFPPYVLRPDDGGPRVTINTAI 621

Query:   513 -----YCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNK 567
                  YC++LPSD FT L P  +   + +   T Y + L LPINSP++ +IV   PM   
Sbjct:   622 GHINRYCARLPSDPFTHLAPKCRTRELPDG--TFY-STLYLPINSPLRASIV-GPPMSCV 677

Query:   568 KTAQMAVALEACRQLHLEGELDDNLLPKGRESIAKLLEHIDEEPDEYAPGIAAKVGSSKR 627
             + A+  VAL  C +LH  GELDD+L+P G+E++ K  E +D   DE    +  + GS+KR
Sbjct:   678 RLAERVVALICCEKLHKIGELDDHLMPVGKETV-KYEEELDLH-DEEETSVPGRPGSTKR 735

Query:   628 KQLYDKKIARALNESFVEADKECFIYAFELERFREAELTLNPKRRKFEDPFNYEYCFGFL 687
             +Q Y K I   L +S+   D+ C++Y   +         LN +RRK   P +   CFG L
Sbjct:   736 RQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGIL 795

Query:   688 SAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTVTAAQLQEIQLFHNYLFTQVLQMCKTGN 747
             +AK IP+IP FPV+ R G + + + +      ++   L+ I   H Y+F+ +L++ K   
Sbjct:   796 TAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLEKPA- 854

Query:   748 LEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKYVSEVVANMENMPRIPKDEVRRQ--YKF 805
             LEF  T +A     ++PLN   D  +  I+ K++ ++  + E    IP  +  ++  + F
Sbjct:   855 LEFKPT-DADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKS-EARIGIPSTKYTKETPFVF 912

Query:   806 NAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPSSKFPDTHFETFNEYFIKKYKLEIYD 865
               EDY+DA+++P YRN +QP  +YVA++  +  P SKFP   +ETF EY+  KY L++ +
Sbjct:   913 KLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTN 972

Query:   866 QNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVSNSSTSNIPQASASDSKESNTSVPHSSQ 925
              NQ LLDVD TS+RLNLL PR  NQ  ++          +P +SA   K    S+ +   
Sbjct:   973 LNQPLLDVDHTSSRLNLLTPRHLNQKGKA----------LPLSSAEKRKAKWESLQN--- 1019

Query:   926 RQILVPELMDIHPISATLWNVIAALPSIFYRVNQLLLTDELRETILVKAFGKEKTKLDDN 985
             +QILVPEL  IHPI A+LW     LPSI YR++ LL  +ELR           +T  D  
Sbjct:  1020 KQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRA----------QTASDAG 1069

Query:   986 VEWNSLAYATEYEEKQTIIVKKIQQLRDLNQKSIEDQERETRENDKIDDGEELFNIGVWD 1045
             V   SL     Y        K I      ++  I      + END       +       
Sbjct:  1070 VGVRSLPADFRYPNLDFGWKKSID-----SKSFISISNSSSAENDNYCKHSTIV------ 1118

Query:  1046 PEEAVRIGVEISSRDDRMDGEDQDTVGLTQGLHDGNISDEDDELPFVMHDYTARLTSNRN 1105
             PE A   G   ++R   ++  DQ +V     L                            
Sbjct:  1119 PENAAHQG---ANRTSSLENHDQMSVNCRTLL---------------------------- 1147

Query:  1106 GIGAWSGSESIVPSGWGDWDGPEPDNSPMPFQILGGPGGLNVQALMADVGRVFDPSTASS 1165
                    SES                          PG L+V+ + AD+       TA +
Sbjct:  1148 -------SES--------------------------PGKLHVE-VSADL-------TAIN 1166

Query:  1166 SLSQTVQESTVSPPKQLTKEEEQFKKLQNDLLKQAKERLEALEMSEDMEKPRRLEDTVNL 1225
              LS    ++  +    L   +  F   Q + L   K+ +          +P       NL
Sbjct:  1167 GLSYN--QNLANGSYDLANRD--F--CQGNQLNYYKQEIPV--------QPTTSYSIQNL 1212

Query:  1226 EDYGDDQENQEDENTPTNFPKTIDEEIEELSIGARKKQEIDDNAAKTDVLERENCEVLPV 1285
               Y    ENQ         P+  DE     ++ + K   +D NA K+         V+P 
Sbjct:  1213 YSY----ENQ---------PQPSDE----CTLLSNKY--LDGNANKSTSDGSPVMAVMPG 1253

Query:  1286 AINEKSRSFSFEKESKAINGRLIRQRSEEYVSHIDSDIGLGVSPCLLLTALTTSNAADGM 1345
               +            + + GR+  ++S   + +  S   LG +P L+L ALT SNA+DG 
Sbjct:  1254 TTDT----------IQVLKGRMDSEQSPS-IGY--SSRTLGPNPGLILQALTLSNASDGF 1300

Query:  1346 SLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQLIV 1405
             +LER E +GDSFLK A T YL+ T  D HEG+LS+ RSK+VSNCNLYRLGKK G+P  +V
Sbjct:  1301 NLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMV 1360

Query:  1406 ANKFDAHDSWLPPCYIPTCDFKAPNTD--------------------DAEEKDNEIERIL 1445
              + FD   +WLPP Y+   D K+ NTD                    D EE+D E E ++
Sbjct:  1361 VSIFDPPVNWLPPGYVVNQD-KS-NTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLM 1418

Query:  1446 ----------DGQVIEEKPENKTGWD-----IGGDVSK------STTDGIETITFPKQAR 1484
                       +   +E   E+    D      G  V K      STTD       PK++ 
Sbjct:  1419 WRAPKEEADYEDDFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSS 1478

Query:  1485 VGN-----------------------------DDI-----SP-------------LPYNL 1497
             +G+                             DD      +P             + Y+L
Sbjct:  1479 LGSMPFSSDFEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDL 1538

Query:  1498 LTQQHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSD-----VP--- 1549
              T+Q I+DKSIAD VEAL+G +L + G       +  +GLKV+   +++D      P   
Sbjct:  1539 HTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRE 1598

Query:  1550 ----------------------SPLLR-----FIDTPT-----NPNASLNFLNNLWQQFQ 1577
                                   S +L+      +  P      +P+A    LN+L   F+
Sbjct:  1599 NFNSQQKNLSVSCAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKT-LNHLISGFE 1657

Query:  1578 FTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLGDAVLDYMITRYLFEDSR 1637
                 E+KI YRFK +AYL+QAFTHASY  N +T CYQRLEFLGDA+LDY+IT++L+ED R
Sbjct:  1658 --NFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPR 1715

Query:  1638 QYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHMIEKFVKLCSERNFDTNF 1697
             Q+SPGVLTDLRSALVNNTIFASLAVK+++ K+F A+ P L+H+I+ FV+   E+N     
Sbjct:  1716 QHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGM 1775

Query:  1698 NAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDSGRNLDTTWQVIFHMMRGT 1757
             ++E+    +EE  DE +EEDIEVPKAMGDIFES+AGAIY+DSG +L+T WQV + MMR  
Sbjct:  1776 DSELRR--SEE--DEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPL 1831

Query:  1758 IELCCANPPRSPIRELMEFEQSKVRFSKMERILESGKVRVTVEVVNNMRFTGMGRNYRIA 1817
             IE   AN PRSP+REL+E E    +FS  ER  + GKVRVTVEVV   +F G+GR+YRIA
Sbjct:  1832 IEKFSANVPRSPVRELLEMEPETAKFSPAERTYD-GKVRVTVEVVGKGKFKGVGRSYRIA 1890

Query:  1818 KATAAKRALKYLHQIEQQ 1835
             K+ AA+RAL+ L   + Q
Sbjct:  1891 KSAAARRALRSLKANQPQ 1908


>sp|Q8R418.2|DICER_MOUSE RecName: Full=Endoribonuclease Dicer; AltName:
            Full=Double-strand-specific ribonuclease mDCR-1
        Length = 1906

 Score = 2120 (751.3 bits), Expect = 1.6e-219, P = 1.6e-219
 Identities = 698/2050 (34%), Positives = 1005/2050 (49%)
 Links = (1)

Query:    11 FNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKRAFFVVE 70
             + PR YQVELL+ A   NTIV L TGSGKTFIAVLL KE   Q+   L+   KR  F+V 
Sbjct:    32 YTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLNPHAKRTVFLVN 91

Query:    71 KVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLIR 130
               N V QQ   +  H+  KVG+      +  W +KE+  Q   +H V+++T    L +++
Sbjct:    92 SANQVAQQVSAVRTHSDLKVGEYSDLEVNASW-TKERWSQEFTKHQVLIMTCYVALTVLK 150

Query:   131 HAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAKVAP 190
             + YL + D+ +L+FDECH A+   HPYR IM   KL +     PR+LGLTAS++  K  P
Sbjct:   151 NGYLSLSDINLLVFDECHLAI-LDHPYREIM---KLCESCPSCPRILGLTASILNGKCDP 206

Query:   191 EKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVIEI 250
             E+L E+++KLE  + S  ETA+DLV L +Y ++P E+V+ C  F     G+  ++ ++  
Sbjct:   207 EELEEKIQKLERILRSDAETATDLVVLDRYTSQPCEIVVDCGPFTDRS-GL--YERLLME 263

Query:   251 FDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELGKII 310
              +  + F+N         + D     K  L   RAV   LGPW A + A +  +EL K I
Sbjct:   264 LEAALDFINDCNVAVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYI 323

Query:   311 KSQVLPDKTLRFLNMAKTSMITIKRLLE----P---EMKKI-----KSIEALRPYVPQRV 358
             K +   +   +FL    T +  I  L E    P   ++K +     K +E LR Y P   
Sbjct:   324 KHEQ-EELHRKFLLFTDTLLRKIHALCEEYFSPASLDLKYVTPKVMKLLEILRKYKPYER 382

Query:   359 IRLFEILETFNPEFQ---------------KERMKLEKAEH---------LSAIIFVDQR 394
              + FE +E +N   Q               +E  + EK E          L  IIFV++R
Sbjct:   383 -QQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPETNFPSPFTNILCGIIFVERR 441

Query:   395 YIAYSLLLMMRHIKSWEPKFKFVNPDYVVGAS-GRNLA-SSDSQGLHKRQTEVLRRFHRN 452
             Y A  L  +++     +P+  +++ +++ G   G+N   S   +   ++Q EVLR+F  +
Sbjct:   442 YTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAH 501

Query:   453 EINCLIATSVLEEGVDVKQCNLVIKFDRPLDMRSYVQSKGRARRAGSRYVIT-------- 504
             E N LIATSV+EEGVD+ +CNLV++FD P + RSYVQSKGRAR   S YV+         
Sbjct:   502 ETNLLIATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYVMLADTDKIKS 561

Query:   505 ---------------------------------VEEKD-------------------TAA 512
                                              V+++D                   TA 
Sbjct:   562 FEEDLKTYKAIEKILRNKCSKSADGAEADVHAGVDDEDAFPPYVLRPDDGGPRVTINTAI 621

Query:   513 -----YCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNK 567
                  YC++LPSD FT L P  +   + +   T Y + L LPINSP++ +IV   PM + 
Sbjct:   622 GHINRYCARLPSDPFTHLAPKCRTRELPDG--TFY-STLYLPINSPLRASIV-GPPMDSV 677

Query:   568 KTAQMAVALEACRQLHLEGELDDNLLPKGRESIAKLLEHIDEEPDEYAPGIAAKVGSSKR 627
             + A+  VAL  C +LH  GELD++L+P G+E++ K  E +D   DE    +  + GS+KR
Sbjct:   678 RLAERVVALICCEKLHKIGELDEHLMPVGKETV-KYEEELDLH-DEEETSVPGRPGSTKR 735

Query:   628 KQLYDKKIARALNESFVEADKECFIYAFELERFREAELTLNPKRRKFEDPFNYEYCFGFL 687
             +Q Y K I   L ES+ + D+ C++Y   +         LN +RRK   P +   CFG L
Sbjct:   736 RQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGIL 795

Query:   688 SAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTVTAAQLQEIQLFHNYLFTQVLQMCKTGN 747
             +AK IP+IP FPV+ R G + + + +     T++   L+ I   H Y+F+ +L++ K   
Sbjct:   796 TAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELITRLHQYIFSHILRLEKPA- 854

Query:   748 LEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKYVSEVVANMENMPRIPKDEVRRQ--YKF 805
             LEF  T  A     ++PLN   D  +  I+ K++ ++  + E    IP  +  ++  + F
Sbjct:   855 LEFKPTG-AESAYCVLPLNVVNDSGTLDIDFKFMEDIEKS-EARIGIPSTKYSKETPFVF 912

Query:   806 NAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPSSKFPDTHFETFNEYFIKKYKLEIYD 865
               EDY+DA+++P YRN +QP  +YVA++  +  P SKFP   +ETF EY+  KY L++ +
Sbjct:   913 KLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTN 972

Query:   866 QNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVSNSSTSNIPQASASDSKESNTSVPHSSQ 925
              NQ LLDVD TS+RLNLL PR  NQ  ++          +P +SA   K    S+ +   
Sbjct:   973 LNQPLLDVDHTSSRLNLLTPRHLNQKGKA----------LPLSSAEKRKAKWESLQN--- 1019

Query:   926 RQILVPELMDIHPISATLWNVIAALPSIFYRVNQLLLTDELRETILVKAFGKEKTKLDDN 985
             +QILVPEL  IHPI A+LW     LPSI YR++ LL  +ELR      A G     L  +
Sbjct:  1020 KQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDA-GVGVRSLPVD 1078

Query:   986 VEWNSLAYATEYEEKQTIIVKKIQQLRDLNQKSIEDQERETRENDKIDDGEELFNIGVWD 1045
               + +L    ++  K++I  K    +   N  S+ + +   + +  +             
Sbjct:  1079 FRYPNL----DFGWKKSIDSKSF--ISTCNS-SLAESDNYCKHSTTVV------------ 1119

Query:  1046 PEEAVRIGVEISSRDDRMDGEDQDTVGLTQGLHDGNISDEDDELPFVMHDYTARLTSNRN 1105
             PE A   G    S    ++  DQ +V                           RL     
Sbjct:  1120 PEHAAHQGATRPS----LENHDQMSVNCK------------------------RL----- 1146

Query:  1106 GIGAWSGSESIVPSGWGDWDGPEPDNSPMPFQILGGPGGLNVQALMADVGRVFDPSTASS 1165
                                    P  SP   Q            +  D+       TA +
Sbjct:  1147 -----------------------PAESPAKLQ----------SEVSTDL-------TAIN 1166

Query:  1166 SLSQTVQESTVSPPKQLTKEEEQFKKLQNDLLKQAKERLEALEMSEDMEKPRRLEDTVNL 1225
              LS    ++  +    L   +  F   Q + L   K+ +          +P       NL
Sbjct:  1167 GLSYN--KNLANGSYDLVNRD--F--CQGNQLNYFKQEIPV--------QPTTSYPIQNL 1212

Query:  1226 EDYGDDQENQEDENTPTNFPKTIDEEIEELSIGARKKQEIDDNAAKTDVLERENCEVLPV 1285
              +Y    ENQ     P+N       E   LS        +D NA  +          +P 
Sbjct:  1213 YNY----ENQPK---PSN-------ECPLLS-----NTYLDGNANTSTSDGSPAVSTMPA 1253

Query:  1286 AINEKSRSFSFEKESKAINGRLIRQRSEEYVSHIDSDIGLGVSPCLLLTALTTSNAADGM 1345
              +N            KA+  R+  ++S   V +  S   LG +P L+L ALT SNA+DG 
Sbjct:  1254 MMNAV----------KALKDRMDSEQSPS-VGY--SSRTLGPNPGLILQALTLSNASDGF 1300

Query:  1346 SLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQLIV 1405
             +LER E +GDSFLK A T YL+ T  D HEG+LS+ RSK+VSNCNLYRLGKK G+P  +V
Sbjct:  1301 NLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMV 1360

Query:  1406 ANKFDAHDSWLPPCYI----------------------------PTCD------FKAPNT 1431
              + FD   +WLPP Y+                              C+      ++AP  
Sbjct:  1361 VSIFDPPVNWLPPGYVVNQDKSNSEKWEKDEMTKDCLLANGKLGEACEEEEDLTWRAPK- 1419

Query:  1432 DDAEEKDNEIE------RILDGQVI---------------------EEKPENK------- 1457
             ++AE++D+ +E      + +D  ++                     E K   K       
Sbjct:  1420 EEAEDEDDFLEYDQEHIQFIDSMLMGSGAFVRKISLSPFSASDSAYEWKMPKKASLGSMP 1479

Query:  1458 ----------TGWDIGG--DVSKSTTDGIETITF--PKQARVGNDD-ISPLPYNLLTQQH 1502
                       + WD     D SK+  +    + F  P +   G D     + Y+L T+Q 
Sbjct:  1480 FASGLEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQC 1539

Query:  1503 ISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKV---IQKDQKSDVPSP-------- 1551
             I+DKSIAD VEAL+G +L + G       +  +GLKV   I++  +     P        
Sbjct:  1540 IADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSREKALDPAQENGSSQ 1599

Query:  1552 ---LLRFIDTPTNPNAS----LNF-------------------LNNLWQQFQFTQLEEKI 1585
                L      P  P +S    L +                   LN+L   F+    E+KI
Sbjct:  1600 QKSLSGSCAAPVGPRSSAGKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFE--TFEKKI 1657

Query:  1586 GYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLGDAVLDYMITRYLFEDSRQYSPGVLT 1645
              YRFK +AYL+QAFTHASY  N +T CYQRLEFLGDA+LDY+IT++L+ED RQ+SPGVLT
Sbjct:  1658 NYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLT 1717

Query:  1646 DLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHMIEKFVKLCSERNFDTNFNAEMYMVT 1705
             DLRSALVNNTIFASLAVK+++ K+F A+ P L+H+I+ FVK   E+N     ++E+    
Sbjct:  1718 DLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVKFQLEKNEMQGMDSELRR-- 1775

Query:  1706 TEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDSGRNLDTTWQVIFHMMRGTIELCCANP 1765
             +EE  DE +EEDIEVPKAMGDIFES+AGAIY+DSG +L+  WQV + MM+  IE   AN 
Sbjct:  1776 SEE--DEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMQPLIEKFSANV 1833

Query:  1766 PRSPIRELMEFEQSKVRFSKMERILESGKVRVTVEVVNNMRFTGMGRNYRIAKATAAKRA 1825
             PRSP+REL+E E    +FS  ER  + GKVRVTVEVV   +F G+GR+YRIAK+ AA+RA
Sbjct:  1834 PRSPVRELLEMEPETAKFSPAERTYD-GKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRA 1892

Query:  1826 LKYLHQIEQQ 1835
             L+ L   + Q
Sbjct:  1893 LRSLKANQPQ 1902


>sp|P84634.1|DCL4_ARATH RecName: Full=Dicer-like protein 4
        Length = 1589

 Score = 471 (170.9 bits), Expect = 8.6e-72, Sum P(5) = 8.6e-72
 Identities = 201/689 (29%), Positives = 323/689 (46%)
 Links = (1)-4-3-2-5

Query:    14 RDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKRAFFVVEKVN 73
             R YQVEL  KAT++N IV LGTG GKT IAV+L+ E G  + +P         F+   V 
Sbjct:   125 RRYQVELCKKATEENVIVYLGTGCGKTHIAVMLIYELGHLVLSPKKSV---CIFLAPTVA 181

Query:    74 LVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLIRHAY 133
             LVEQQA  I    +FKV  +H      +  S  + ++ +  + V+V+T Q LL  ++H +
Sbjct:   182 LVEQQAKVIADSVNFKVA-IHCG-GKRIVKSHSEWEREIAANEVLVMTPQILLHNLQHCF 239

Query:   134 LKIEDMCVLIFDECHHALG-SQHPYRSIM-VDYKLLKKDKPVPRVLGLTASLIKAKVAPE 191
             +K+E + +LIFDECHHA   S HPY  IM V YK     +P  R+ G+TAS +  K  P 
Sbjct:   240 IKMECISLLIFDECHHAQQQSNHPYAEIMKVFYKSESLQRP--RIFGMTASPVVGKDGPP 297

Query:   192 KLMEQLKKLESAMDSVIETASDLVSLSKY-GAKPYEVVIICKDFEIGCLGIPNFDTV-IE 249
               ++       +  S    +  + SL     AK Y V     +  +   G  +   V + 
Sbjct:   298 --LDSFTYFSGSFQSE-NLSKSINSLENLLNAKVYSV-----ESNVQLDGFVSSPLVKVY 349

Query:   250 IFDETVAFVNTTTEFHPDL--DLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELG 307
              +   ++  + +T  + ++  D+  RR     L+   A   QL          V ++ +G
Sbjct:   350 YYRSALSDASQSTIRYENMLEDIKQRRANVYCLRFLEAAKIQLNS-----DHNVQDEPVG 404

Query:   308 KIIKSQVLPDKTLRFLNMAKTSMIT-IKRLLEPEMKKIKSIEALR-PYVPQRVIRLFEIL 365
             K  KS++       +L+MA  ++ + + +  +     + S+ AL+ P   +++++L +IL
Sbjct:   405 KNPKSKICDT----YLSMAAEALSSGVAK--DENASDLLSLAALKEPLFSRKLVQLIKIL 458

Query:   366 ETFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHI---KSWEPKFKFVNPDYV 422
               F         +LE   H+  IIFV++   A +L  ++ ++   +SW+        D++
Sbjct:   459 SVF---------RLEP--HMKCIIFVNRIVTARTLSCILNNLELLRSWKS-------DFL 500

Query:   423 VGASGRNLASSDSQGLHKRQTE-VLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRP 481
             VG S      S  + + +R  E +L+RF   E+N L+AT V EEG+D++ C LVI++D P
Sbjct:   501 VGLS------SGLKSMSRRSMETILKRFQSKELNLLVATKVGEEGLDIQTCCLVIRYDLP 554

Query:   482 LDMRSYVQSKGRARRAGSRYVITVE---EKD----------------------------- 509
               + S++QS+GRAR   S Y   V+   EK+                             
Sbjct:   555 ETVTSFIQSRGRARMPQSEYAFLVDSGNEKEMDLIENFKVNEDRMNLEITYRSSEETCPR 614

Query:   510 ----------TAA-------------YCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAEL 546
                       T A             YCS+LP D F +  P  Q  P++E G T  C  +
Sbjct:   615 LDEELYKVHETGACISGGSSISLLYKYCSRLPHDEFFQPKPEFQFKPVDEFGGT-IC-RI 672

Query:   547 LLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRESIAKLLEH 606
              LP N+PI    +  + +P+ + A+    L+A  +LH  G L+D LLP  ++ I   L  
Sbjct:   673 TLPANAPISE--IESSLLPSTEAAKKDACLKAVHELHNLGVLNDFLLPDSKDEIEDELS- 729

Query:   607 IDEEPDEYAPGIAAKVGSSKRKQLYDKKI 635
              D+E D     I  + G S R  LY+ ++
Sbjct:   730 -DDEFD--FDNIKGE-GCS-RGDLYEMRV 753

 Score = 290 (107.1 bits), Expect = 8.6e-72, Sum P(5) = 8.6e-72
 Identities = 76/182 (41%), Positives = 99/182 (54%)
 Links = 1-4-3-(2)-5

Query:  1506 KSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKV-IQKDQKSDVPSPLLRFIDTPTNPNA 1564
             K+IAD VEAL+G  L+  G    +K + W+G+ V  +  Q  D      R++   T    
Sbjct:  1162 KTIADVVEALVGAFLVDSGFKGAVKFLKWIGVNVDFESLQVQDACIASRRYLPLTTR--- 1218

Query:  1565 SLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFLGDAVL 1624
                  NNL        LE ++ Y+F  +  LVQAF H SY N    GCYQRLEFLGDAVL
Sbjct:  1219 -----NNL------ETLENQLDYKFLHKGLLVQAFIHPSY-NRHGGGCYQRLEFLGDAVL 1266

Query:  1625 DYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLY-H-MIE 1682
             DY++T Y F    +  PG LTDLRS  VNN   A++AV F   K F+  C  +Y H +IE
Sbjct:  1267 DYLMTSYFFTVFPKLKPGQLTDLRSLSVNNEALANVAVSFSL-KRFL-FCESIYLHEVIE 1324

Query:  1683 KF 1684
              +
Sbjct:  1325 DY 1326

 Score = 109 (43.4 bits), Expect = 8.6e-72, Sum P(5) = 8.6e-72
 Identities = 28/59 (47%), Positives = 38/59 (64%)
 Links = 1-4-(3)-2-5

Query:  1327 VSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLY--HTLLDQHEGKLSFARS 1383
             VS   +L ALTT    + +SLER E +GD+FLKFA + +L+  H  LD  EG+L+  RS
Sbjct:  1044 VSGHRVLEALTTEKCHERLSLERLEVLGDAFLKFAVSRHLFLHHDSLD--EGELTRRRS 1100

 Score = 58 (25.5 bits), Expect = 8.6e-72, Sum P(5) = 8.6e-72
 Identities = 14/42 (33%), Positives = 25/42 (59%)
 Links = 1-(4)-3-2-5

Query:   931 PEL--MDIHPISATLWNVIAALPSIFYRVNQLLLTDELRETI 970
             PEL  + I  +S  + + ++ LPSI +R+  LL+  EL+  +
Sbjct:   993 PELSHLKIKGLSKDIGSSLSLLPSIMHRMENLLVAIELKHVL 1034

 Score = 57 (25.1 bits), Expect = 8.6e-72, Sum P(5) = 8.6e-72
 Identities = 22/79 (27%), Positives = 33/79 (41%)
 Links = 1-4-3-2-(5)

Query:  1765 PPRSPIRELMEFEQSKVRFSKMERILESGKVRVTVEVVNN---MRFTGMGRNYRIAKATA 1821
             P  SPI+EL+E  QS     ++    + G   V ++V  N   +  +  GRN R     A
Sbjct:  1346 PKISPIKELIELCQSYKWDREISATKKDGAFTVELKVTKNGCCLTVSATGRNKREGTKKA 1405

Query:  1822 AKRALKYLHQIEQQRRQSP 1840
             A+  +  L   E      P
Sbjct:  1406 AQLMITNLKAHENITTSHP 1424


>sp|Q7S8J7.1|DCL1_NEUCR RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease dcl-1; Includes: RecName: Full=ATP-dependent
            helicase dcl-1
        Length = 1584

 Score = 505 (182.8 bits), Expect = 3.0e-69, Sum P(6) = 3.0e-69
 Identities = 164/507 (32%), Positives = 269/507 (53%)
 Links = (1)-4-6-3-2-8

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKR--AFFVV 69
             +PR+YQVEL ++A ++NTI  L TGSGKT IA +LL+          ++G  R  AFF+V
Sbjct:   121 SPREYQVELFERAKQQNTIAVLDTGSGKTLIAAMLLRWVITGELEDREKGLPRRIAFFLV 180

Query:    70 EKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLI 129
             +KV LV QQ   +  +  F + ++ G+   G+ +SK    + ++++ VVV TA+ L   +
Sbjct:   181 DKVALVFQQHSFLTKNLDFPMEKLCGEMVEGV-ESKAFWKEALEQNEVVVCTAEILSTAL 239

Query:   130 RHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAKVA 189
              H++++++ + +LIFDE HH     HPY  I+ ++ + ++ +  PR+LGLTAS + AKV 
Sbjct:   240 HHSWIRMDQINLLIFDEAHHTK-KDHPYARIIKNFYIDEQLERRPRILGLTASPVDAKVD 298

Query:   190 PEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVIE 249
             P +   +L   E+ + S I TA+D  +L     KP   +++  ++     G P+ +TV+ 
Sbjct:   299 PRRAAAEL---EALLHSQIATAADPAALQHTICKPKTELVV--EY---VRGRPDSETVLN 350

Query:   250 IFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELGKI 309
                +    V     F        ++P+     TT A  + LG W A R  Q++ K+   I
Sbjct:   351 --KQLRKLVGGQELF--------KKPLNF---TTSAASK-LGTWCADRYWQLFFKQ-EDI 395

Query:   310 IKSQVLPDKTLRFLNMAKTSMIT---IKRLLEP-EMKKIKSIE--ALRP-YVPQRVIRLF 362
             +K +   ++ L  + +A    IT   +K++ E  E+    +    AL P  +  +VI L 
Sbjct:   396 VKLESRTERDL--MKVAALDEITEKHVKQVREAHELVNAHTFSPAALDPTMLSSKVIMLV 453

Query:   363 EILETFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSL--LLMMRHIKSWEPKFKFVNPD 420
              IL     +F++       A+    IIFV QR  A  L  LL    IKS  P    +  +
Sbjct:   454 RILRD---QFERG----VGAQR--CIIFVRQRNTAMLLADLLQQPEIKSHIPS---IAAE 501

Query:   421 YVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR 480
              +VG      +  +++   ++Q  ++R+F   EINCL ATSV EEG+D+  CN+VI+FD 
Sbjct:   502 VLVGGGTTGSSYVNAKINFQQQNRIIRKFKLGEINCLFATSVAEEGLDIPDCNIVIRFDL 561

Query:   481 PLDMRSYVQSKGRARRAGSRYVITVEE 507
                +   +QS+GRARR  SRY+  +E+
Sbjct:   562 YDTLIQCIQSRGRARRPDSRYIQMIEK 588

 Score = 233 (87.1 bits), Expect = 3.0e-69, Sum P(6) = 3.0e-69
 Identities = 81/263 (30%), Positives = 117/263 (44%)
 Links = 1-4-6-3-(2)-8

Query:  1500 QQHI-SDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPS--PLLRFI 1556
             Q+H+ +DKSIAD  EALIG   LT G       M    +  + KD+K  + S        
Sbjct:  1182 QRHVLADKSIADVCEALIGAAYLT-GQEKGSFDMAIKAVTAMVKDKKHRMISYGDYYAVY 1240

Query:  1557 DTPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASY--INNRVTGCYQ 1614
               PT    S N      Q+    +  E++GY+FK    L  AF H +Y  +  R+   YQ
Sbjct:  1241 QKPTWQTESANSA----QRDMAKKFSERMGYKFKHPRLLRAAFQHPTYPSLYERLPS-YQ 1295

Query:  1615 RLEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMC 1674
             RLEFLGDA+ D +   YLF       P  LT+ + A+V+N     L+    F K    M 
Sbjct:  1296 RLEFLGDALFDMVAVDYLFRKFPAADPQWLTEHKMAMVSNQFLCCLSFHLGFNKCIATMS 1355

Query:  1675 PGLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDI----EVPKAMGDIFES 1730
             P +   I ++V    E   +T     +    T +E        I     +PK + D+ E+
Sbjct:  1356 PSILKDIAEYVTEIEEA-LETAKQEAINAGKTADEYSRDYWVHITHASRLPKCLSDVVEA 1414

Query:  1731 VAGAIYLDSGRNLDTTWQVIFHM 1753
               GAI++DS  +     Q  F+M
Sbjct:  1415 YIGAIFVDSEYDYSVV-QNFFNM 1436

 Score = 109 (43.4 bits), Expect = 3.0e-69, Sum P(6) = 3.0e-69
 Identities = 49/187 (26%), Positives = 86/187 (45%)
 Links = 1-4-6-(3)-2-8

Query:  1249 DEEIEELSIGARKKQEIDDNAAKTDVLERENCEVL--PVAINEKSRSFSFEKESKAINGR 1306
             D+ + E ++ + ++  +DD     DV E + C ++  P+ I+        +  +  +   
Sbjct:   987 DQPVVEAALISTRRDFLDDTLRDEDV-EPQQCFLILEPMRISP----IPADVVAMLLCFP 1041

Query:  1307 LIRQRSEEYVSHIDSD--IGLGVSPCLLLTALTT-SNAAD-----------GM--SLERF 1350
              I  R E  +  +D+   +GL + P L L A T  S+ +D           GM  + ER 
Sbjct:  1042 SIIHRVESNLVALDACKLLGLDLRPDLALEAFTKDSDNSDEHDAEKENFQTGMGDNYERL 1101

Query:  1351 ETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQLIVANKFD 1410
             E +GDSFLK ATT  +Y  + D+ E +    R   + N NL+    ++G+ + I +  F+
Sbjct:  1102 EFLGDSFLKMATTIAIYTLIPDKGEFEYHVERMLLICNKNLFNNALEIGLEEYIRSMSFN 1161

Query:  1411 AHDSWLP 1417
                 W P
Sbjct:  1162 RRQ-WYP 1167

 Score = 69 (29.3 bits), Expect = 3.0e-69, Sum P(6) = 3.0e-69
 Identities = 28/82 (34%), Positives = 40/82 (48%)
 Links = 1-(4)-6-3-2-8

Query:   511 AAYCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTA 570
             A + + LP    T L P   I  +   G    C E+++P  SPIK A+  K  + +K  A
Sbjct:   659 ANFTATLPHPPETSLSPEYYITTVP-GGFQ--C-EVVMPDASPIKSAVG-KVHL-SKGVA 712

Query:   571 QMAVALEACRQLHLEGELDDNL 592
             + A A E C  L   G LD++L
Sbjct:   713 KCAAAFELCLALLKAGHLDNHL 734

 Score = 65 (27.9 bits), Expect = 1.0e-64, Sum P(6) = 1.0e-64
 Identities = 21/69 (30%), Positives = 36/69 (52%)
 Links = 1-4-6-(5)-2-8

Query:   925 QRQILVPELMDIHPISATLWNVIAALPSIFYRV-NQLLLTD-------ELRETILVKAFG 976
             Q+  L+ E M I PI A +  ++   PSI +RV + L+  D       +LR  + ++AF 
Sbjct:  1015 QQCFLILEPMRISPIPADVVAMLLCFPSIIHRVESNLVALDACKLLGLDLRPDLALEAFT 1074

Query:   977 KEKTKLDDN 985
             K+    D++
Sbjct:  1075 KDSDNSDEH 1083

 Score = 49 (22.3 bits), Expect = 3.0e-69, Sum P(6) = 3.0e-69
 Identities = 44/220 (20%), Positives = 84/220 (38%)
 Links = 1-4-(6)-3-2-8

Query:   687 LSAKEIPKIPPFPVFLRQGNM-KVRLIVAPKKTTVTAAQLQEIQLFHNYLFTQVLQMCKT 745
             LS   +P++  FP+F       KVR +  P         ++++  F    F  V      
Sbjct:   801 LSRSALPEVASFPLFFGTKRFSKVRCVPIPGSVQADDTLVEQLTRFTLKAFMDVFSK--- 857

Query:   746 GNLEFDGTS-NAPLNTLIVPLN-------KRKDDMSYTINMKYVSEVVANMENMPR--IP 795
                E++ T+ N P    + P++       +     ++ I+ K ++ V  N E +P   + 
Sbjct:   858 ---EYEATAVNLPY--FLSPMDGGHGFDFRLAKSPAHLIDRKALAYVSEN-EKVPYTFLE 911

Query:   796 KDEVRRQYKFNAEDYKDAI-VMPWYRNLEQPVFYYVAE--ILPEWRPSSKFPDTH--FET 850
              D+   Q KF  + Y  A      +R  +      V +  + P  R       TH     
Sbjct:   912 PDDFF-QDKFVVDPYDGARKFFTHHRRHDMKPTDPVPDGIVAPNHRAWRGLGTTHDILNY 970

Query:   851 FNEYFIKKYKLEIYDQNQSLLDVDFTSTRLNLLQPRIQNQ 890
              N  + K     I+  +Q +++    STR + L   ++++
Sbjct:   971 SNSLWSKSRGFMIFQADQPVVEAALISTRRDFLDDTLRDE 1010

 Score = 45 (20.9 bits), Expect = 4.1e-60, Sum P(4) = 4.1e-60
 Identities = 25/88 (28%), Positives = 41/88 (46%)
 Links = 1-(7)-2-8

Query:   535 EENGVTKYCAELLLPIN-SPIKH---AIVLKNPMPNKKTAQMAVALEACRQLHLEGELDD 590
             +E+   + C  +L P+  SPI     A++L  P    +     VAL+AC+ L L+   D 
Sbjct:  1009 DEDVEPQQCFLILEPMRISPIPADVVAMLLCFPSIIHRVESNLVALDACKLLGLDLRPDL 1068

Query:   591 NLLPKGRESIAKLLEHIDEEPDEYAPGI 618
              L    ++S     EH D E + +  G+
Sbjct:  1069 ALEAFTKDS-DNSDEH-DAEKENFQTGM 1094

 Score = 40 (19.1 bits), Expect = 3.0e-69, Sum P(6) = 3.0e-69
 Identities = 10/26 (38%), Positives = 16/26 (61%)
 Links = 1-4-6-3-2-(8)

Query:  1815 RIAKATAAKRALKYLH--QIEQQRRQ 1838
             R AK+  AK+A+K L    +E+ R +
Sbjct:  1529 RYAKSAMAKKAIKLLEGMSVEEFRER 1554


>sp|A4RKC3.2|DCL1_MAGGR RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease DCL1; Includes: RecName: Full=ATP-dependent
            helicase DCL1
        Length = 1591

 Score = 481 (174.4 bits), Expect = 3.5e-69, Sum P(6) = 3.5e-69
 Identities = 152/502 (30%), Positives = 238/502 (47%)
 Links = (1)-4-5-7-3-2

Query:    13 PRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEY-GVQLFAPLDQGGKR-AFFVVE 70
             PR+YQ+EL ++A +KNTI  L TG+GKT IA+LL++    ++L A      KR  FF+V+
Sbjct:   108 PREYQIELFERAKQKNTIAVLDTGTGKTLIAILLIRHIIELELGARWQGREKRITFFLVD 167

Query:    71 KVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLIR 130
             KV LV QQ  HI  +  F V  +HG T   LW SKE  ++ ++   VVV TA+ L   + 
Sbjct:   168 KVALVRQQTDHIRANLDFPVTGLHGDTVRNLWYSKEYFEKLLQEQEVVVCTAEILYRCLH 227

Query:   131 HAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKD-KPVPRVLGLTASLIKAKVA 189
              +YL I  + +++FDE HHA    H Y  I+ D+ L+++D +  PR+ G+TAS I  K  
Sbjct:   228 RSYLNISQVSLVVFDEAHHAK-KNHVYARIIKDFYLMEEDCQKRPRIFGMTASPIDTKDT 286

Query:   190 PEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVIE 249
                      +LES + S I T SD   L   G++P EV               ++  V+ 
Sbjct:   287 CISYERATHELESLLHSEIATISDRDLLKVIGSRPQEVR-------------KSYARVLR 333

Query:   250 IFDETVAFVNTTTEFHPDLDLDPRRPI-KDSLKTTRAVFRQLGPWAAWRTAQV-WEKELG 307
                E     N   E      L    P+ K +  +      +LG W A +  ++ + +E  
Sbjct:   334 --QENTELCNQLRE------LVGNHPLFKQTFDSAEFAVTELGAWCADKLWELCFREEAV 385

Query:   308 KIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILET 367
               +  +V   +  R  +    S   +    E  +  ++      P       +  +++E 
Sbjct:   386 STLDGRVEGSRA-RDPDEVGESSHEVSNAREA-LSLVQQWSFSPPEDGSLSTKTHKLIEI 443

Query:   368 FNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSL--LLMMRHIKSWEPKFKFVNPDYVVGA 425
                 F +          +  I+FV +R  A  L  L     I++  P  K     +++GA
Sbjct:   444 LAECFSQA----SAGNAIQCIVFVKRRDTAVLLNALCEQAEIRTKIPDLKGA---FLIGA 496

Query:   426 S-GRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPLDM 484
               G N A + +    ++Q + + RF   EINCL ATS+ EEG+D+  CN+VI+FD     
Sbjct:   497 GRGGNAAFTTT----RQQEQTVSRFRDGEINCLFATSIAEEGLDIPGCNVVIRFDLHGTT 552

Query:   485 RSYVQSKGRARRAGSRYVITVE 506
               Y+QS+GRAR   S ++   E
Sbjct:   553 IQYIQSRGRARMRNSWFIHMTE 574

 Score = 251 (93.4 bits), Expect = 3.5e-69, Sum P(6) = 3.5e-69
 Identities = 83/256 (32%), Positives = 125/256 (48%)
 Links = 1-4-5-7-3-(2)

Query:  1501 QH-ISDKSIADAVEALIGVHLLTL----GPN-----PTLKVMNWMGLKVIQ--KDQKSDV 1548
             +H + DKSIAD  EALIG   LT      PN       + VM       +Q   D  +  
Sbjct:  1166 EHALGDKSIADVCEALIGAAYLTAQAQSSPNFDLAVKAVTVMTHSKTHTMQAWSDYYASY 1225

Query:  1549 PSPLLRFIDTPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNR 1608
               P   ++ TP  P+ +        Q    +Q++ K+GYRFK    L  AF H SY    
Sbjct:  1226 QCP--EWLSTP--PSQT--------QLELCSQIKNKMGYRFKNPRLLRCAFMHPSYPRQY 1273

Query:  1609 VT-GCYQRLEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQ 1667
                  YQRLEFLGD++LD +   YLF+      P  LT+ + A+V+N  F  +AV   F 
Sbjct:  1274 ENIPSYQRLEFLGDSLLDMVCVDYLFKKHPDKDPQWLTEHKMAMVSNQFFGCVAVGLGFH 1333

Query:  1668 KHFIAMCPGLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEV---PKAM 1724
             +H I M P L   I ++ +L +++  +     ++ +   + E D  ++  IEV   PK +
Sbjct:  1334 RHLIHMQPALGGSITEWAELVTKKREEAR---QLAVRRGQREEDYARDFWIEVHHPPKCL 1390

Query:  1725 GDIFESVAGAIYLDSG 1740
              DI E+  GA+++D+G
Sbjct:  1391 PDILEAYVGALFVDTG 1406

 Score = 99 (39.9 bits), Expect = 3.5e-69, Sum P(6) = 3.5e-69
 Identities = 25/75 (33%), Positives = 39/75 (52%)
 Links = 1-4-5-7-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQL 1403
             G + ER E +GD FLK AT+  LY TL++  E +    R  ++ N NL     +  + + 
Sbjct:  1079 GQNYERLEFLGDCFLKMATSIALY-TLVEGDEFEYHVERMLDICNKNLLNWALESNLQEH 1137

Query:  1404 IVANKFDAHDSWLPP 1418
             I +  F+   +W PP
Sbjct:  1138 IRSKSFNRR-TWYPP 1151

 Score = 70 (29.7 bits), Expect = 3.5e-69, Sum P(6) = 3.5e-69
 Identities = 20/60 (33%), Positives = 34/60 (56%)
 Links = 1-(4)-5-7-3-2

Query:   545 ELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRESIAKLL 604
             E+ LP +SP++ A  +     +K+ A+ A A   C QL+    LDD+L    + ++AK+L
Sbjct:   674 EVYLPASSPLRSA--MGGVYRSKQLAKCAAAYAMCIQLYNSNYLDDHL----KSTLAKVL 727

 Score = 65 (27.9 bits), Expect = 3.5e-69, Sum P(6) = 3.5e-69
 Identities = 35/168 (20%), Positives = 70/168 (41%)
 Links = 1-4-(5)-7-3-2

Query:   687 LSAKEIPKIPPFPVFLRQGNMK---VRLIVAPKKTTVTAAQLQEIQLFHNYLFTQVLQMC 743
             L+ K +P+I  FP+F  +G+ +   VR I      + T  Q++ I  F   +F  +    
Sbjct:   786 LTRKPLPEIAQFPLFFGKGSSRRSNVRCIPLAHPWSPTTTQVEGICAFTLCIFRDIFSK- 844

Query:   744 KTGNLEFDGTSNAPLNTLIVPLN--KRKDDMSYTINMKYVSE--VVANMENMPRIPKDEV 799
                + +  GT + P    + P    +   D+S  +N + + +   V       R+P    
Sbjct:   845 ---DFQASGT-DMPY--FLAPSTGIEHGTDLSSLVNPERIIDWATVHRTTTTDRVP---- 894

Query:   800 RRQYKFNAED--YKDAIVMPWYRNLEQPVFYYVAEILPEWRPSSKFPD 845
                Y FN  D  ++D  V   +    +   +++ ++  + +P  K P+
Sbjct:   895 ---YNFNEPDEFFQDKYVSDPFDGSRK---FFMRKVRRDLKPQDKVPE 936

 Score = 51 (23.0 bits), Expect = 3.9e-66, Sum P(4) = 3.9e-66
 Identities = 33/139 (23%), Positives = 58/139 (41%)
 Links = 1-(6)-3-2

Query:   490 SKGRA-RRAGSRYVITVEEKDTAAYCSKLPSDIF-TRLVPHNQIIPIEENGV------TK 541
             SK RA       Y +++ +K  A + S+    +    L P  + +  E +G       T 
Sbjct:   942 SKWRAVEHTILNYSVSLWKKSRAGHNSRQDQPVVEAELAPLRRNLLDETDGENSTGPQTC 1001

Query:   542 YCA-ELLLPINSPIKHAIVLKN-PMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRES 599
             Y   E LL    P+   ++    P    +     ++LEAC+ L L+  +D  L+   ++S
Sbjct:  1002 YLVLETLLISQIPVDTVVMAYTFPAIIYRLENSLISLEACQNLGLDIPIDIALIAMTKDS 1061

Query:   600 IAKLLEHIDEEPDEYAPGI 618
                  +H DE P  +  G+
Sbjct:  1062 -DNSDDH-DEAPINFQSGM 1078

 Score = 40 (19.1 bits), Expect = 3.5e-69, Sum P(6) = 3.5e-69
 Identities = 8/26 (30%), Positives = 13/26 (50%)
 Links = 1-4-5-(7)-3-2

Query:  1231 DQENQED-ENTPTNFPKTIDEEIEEL 1255
             D +N +D +  P NF   + +  E L
Sbjct:  1060 DSDNSDDHDEAPINFQSGMGQNYERL 1085


>sp|Q0CW42.2|DCL1_ASPTN RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease dcl1; Includes: RecName: Full=ATP-dependent
            helicase dcl1
        Length = 1519

 Score = 464 (168.4 bits), Expect = 4.8e-65, Sum P(6) = 4.8e-65
 Identities = 159/512 (31%), Positives = 242/512 (47%)
 Links = (1)-4-5-9-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEY-GVQLFAPLDQGGKR-AFFVV 69
             NPR+YQ+EL ++A  +NTI  L TGSGKT IAVLLLK     +L    +    R +FF+V
Sbjct:   108 NPREYQIELFERAKVQNTIAVLDTGSGKTLIAVLLLKHVIQTELIDRANGNPPRISFFLV 167

Query:    70 EKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLI 129
             + V LV QQA  +  +    V    G     LW+ +   + F K + V+V TA+ L   +
Sbjct:   168 DSVTLVYQQASVLRNNLDQNVAHFFGAMGVDLWNKQTWAEHFEK-NMVIVCTAEILNQCL 226

Query:   130 RHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAKVA 189
              +AY+ ++ + +L+FDE HH     HPY  I+ D  L       PR+ G+TAS +  K  
Sbjct:   227 LNAYITMQQINLLVFDEAHHTK-KDHPYARIIRDSYLRVPPSSRPRIFGMTASPVDTK-- 283

Query:   190 PEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVIE 249
                ++E  + LE+ +DS I T S L  L +   +P E V I    +      P F + + 
Sbjct:   284 -GDVLEAARNLEALLDSKIATTSKLTILRQVVNRPNEEVWIYDKLQ------PTFTSDLY 336

Query:   250 IFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELGKI 309
                E+         F     L+P        +  R    +LG W A R   VW   L   
Sbjct:   337 KLMES--------RFGDISHLEPM------FRFARHATSELGTWCADR---VWVSALADD 379

Query:   310 IKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILETFN 369
             +  +V  + ++     + T +  + + +  ++ +IK    L    P       E L +  
Sbjct:   380 VLPKV--EGSIGGKRQS-TGLGQLPKDVHRDITRIKEASELVESHPPNDPGAPEALSSKV 436

Query:   370 PEFQKERMKLEKAE-HLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYVVGASGR 428
                 KE  +    E +   I+F ++RY A  L  +   +    P  +   P  ++G    
Sbjct:   437 RVLWKEISQCFGQETNTKCIVFTEKRYTAKVLFDLFTVLNV--PGLR---PGVLIG---- 487

Query:   429 NLASSDSQGLH---KRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPLDMR 485
              + SSD  G++   ++Q   + RF   EINCL AT+V EEG+D+  CNLV++FD    + 
Sbjct:   488 -VRSSDRIGMNVTFRQQILTMVRFRTGEINCLFATAVAEEGLDIPDCNLVVRFDLYKTLI 546

Query:   486 SYVQSKGRARRAGSRYVITVEEKDTAAYCSKL 517
              YVQS+GRAR A S Y   +E KD A + S L
Sbjct:   547 QYVQSRGRARHADSTYASMIE-KDNADHESIL 577

 Score = 208 (78.3 bits), Expect = 4.8e-65, Sum P(6) = 4.8e-65
 Identities = 91/350 (26%), Positives = 148/350 (42%)
 Links = 1-4-5-9-3-(2)

Query:  1503 ISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQK--DQKSDVPSPLLRFIDTPT 1560
             +++K+IAD  EALIG  LLT GP         MG++ +    D      +    +I   +
Sbjct:  1163 LAEKTIADVCEALIGAALLTPGPQHRFD----MGVRAVSAVVDSNEHNAASWRDYISLYS 1218

Query:  1561 NPNASLNFLNNLWQQFQFTQ-LEEKIGYRFKERAYLVQAFTHASYINN--RVTGCYQRLE 1617
              P       +    +    + +EEK+GY F+    L  AFTH SY +   RV  CYQ LE
Sbjct:  1219 IPKYQEQAPDG--SEIDLCRRVEEKLGYHFRYPRLLHSAFTHPSYPSAWARVP-CYQSLE 1275

Query:  1618 FLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGL 1677
             FLGDA+LD +    LF       P  LT+ + A+V+N    +LAVK     H       L
Sbjct:  1276 FLGDALLDMVCVEDLFRRFPDRDPQWLTEHKMAMVSNKFLGALAVKLGLHTHLSYFSSAL 1335

Query:  1678 YHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKA-MGDIFESVAGAIY 1736
                I  + +        ++   + + +T +             PK  + D+ E+  GA++
Sbjct:  1336 QSQITHYAEEAQAAASQSDVAVDYWTLTQDP------------PKVCLPDMVEAYLGAVF 1383

Query:  1737 LDSG---RNLDTTWQV----IFHMMRGTIELCCANPPRSPIRELMEFEQSKVRFS-KMER 1788
             +DS      ++  +Q      FH M    +      P + +   +  E   + +  K   
Sbjct:  1384 VDSNFRFEEVEVFFQQHIKPYFHDM-AIYDTFANRHPTTFLHNKLTNEYGCLNYCLKAGE 1442

Query:  1789 IL----ESGKVRVTVEVVNNMRFTGMGRNYRIAKATAAKRALKYLHQIEQ 1834
             I     ++  V   V V + +  TG+  + R AK  A++ AL  L  I++
Sbjct:  1443 IPGADGDASTVLAAVIVHDTILTTGVASSGRYAKVKASENALTELLHIDR 1492

 Score = 94 (38.1 bits), Expect = 4.8e-65, Sum P(6) = 4.8e-65
 Identities = 25/74 (33%), Positives = 37/74 (50%)
 Links = 1-4-5-9-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQL 1403
             G + ER E +GD FLK AT+  L++   D +E      R   + N NL+    K  + Q 
Sbjct:  1068 GKNYERLEFLGDCFLKMATSISLFNQHPDDNEFDYHVNRMCLICNRNLFNSAVKKELYQF 1127

Query:  1404 IVANKFDAHDSWLP 1417
             I +  F + D+W P
Sbjct:  1128 IRSRGF-SRDTWYP 1140

 Score = 85 (35.0 bits), Expect = 4.8e-65, Sum P(6) = 4.8e-65
 Identities = 27/82 (32%), Positives = 38/82 (46%)
 Links = 1-(4)-5-9-3-2

Query:   511 AAYCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTA 570
             A Y S L  +  T       ++P+ +     Y  E++LP  SPI+ A  +  P   K TA
Sbjct:   639 ARYASSLQYENDTSAQVTYVVLPVND----AYVCEVILPEKSPIRGATGM--PAMKKSTA 692

Query:   571 QMAVALEACRQLHLEGELDDNL 592
             +   A EACR L     LD+ L
Sbjct:   693 KRYAAFEACRLLRKHRLLDEYL 714

 Score = 76 (31.8 bits), Expect = 4.8e-65, Sum P(6) = 4.8e-65
 Identities = 50/220 (22%), Positives = 88/220 (40%)
 Links = 1-4-(5)-9-3-2

Query:   692 IPKIPPFPVFLRQGNMKVRLIVAPKKTTV--TAAQLQEIQLFHNYLFTQVLQMCKTGNLE 749
             +P+ P FP+FL + +++  ++  P    +  +A +L  +  F   +F  V +  KT + E
Sbjct:   788 LPQFPTFPIFLGE-DVETIVLTVPVNMELQPSADELDYMTTFTLRIFRDVFR--KTYDKE 844

Query:   750 FDGTSNAPLNTLIVPLNKRKDDMSYTINMKYVSEVVANMENMPRIPKDEVRRQYKFNAED 809
              +      L  +  P N+  D     +N + +S V           +D++  Q     E 
Sbjct:   845 PEKLPYWLLPAISFPCNQEADPRD-VVNWEILSSVHE---------RDDIEYQADMPPEM 894

Query:   810 YKDAIVMPWYRNLEQPVFYYVAEILPEWRPSSKFPD-----THFETFNEYFIKKYK---- 860
               D  V   Y + +    Y+   +    +PSS  P       H +T   Y I   K    
Sbjct:   895 LVDRFV---YDHWDGRYRYFTLAVDENLQPSSPPPSHVARRRHMDTIMNYSISLSKNSRA 951

Query:   861 --LEIYDQNQSLLDVDFTSTRLNLLQPRIQNQPRRSRTVS 898
               L   + NQ +L  +    R NLL  R+ ++ R+  T S
Sbjct:   952 KFLSRCNWNQPVLHAELVRLRRNLLD-RMTDKERKLETRS 990

 Score = 49 (22.3 bits), Expect = 3.5e-58, Sum P(5) = 3.5e-58
 Identities = 20/74 (27%), Positives = 31/74 (41%)
 Links = 1-(6)-10-3-2

Query:  1028 ENDKIDDGEELFNIGVWDPEEAVRIGVEISSRDDRMDGEDQDTVGLTQGLHDGNISDEDD 1087
             E D  D   E   + V D E+ ++   ++   D  + G D DT        D  +  E+ 
Sbjct:   567 EKDNAD--HESILVQVNDAEKIMQSFCQLLPEDRILHGNDDDT--------DAVLDREEW 616

Query:  1088 ELPFVMHDYTARLT 1101
             E P+ +    ARLT
Sbjct:   617 EEPYTLPSTAARLT 630

 Score = 41 (19.5 bits), Expect = 2.2e-58, Sum P(4) = 2.2e-58
 Identities = 8/16 (50%), Positives = 12/16 (75%)
 Links = 1-(7)-3-2

Query:   574 VALEACRQLHLEGELD 589
             + LEAC++L LE  L+
Sbjct:  1025 IGLEACKKLGLEISLE 1040

 Score = 39 (18.8 bits), Expect = 3.8e-57, Sum P(5) = 3.8e-57
 Identities = 15/79 (18%), Positives = 35/79 (44%)
 Links = 1-(8)-9-3-2

Query:   729 QLFHNYLFTQVLQMCKTGNLEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKYVSEVVANM 788
             +L H+   T + +   +  L+++  ++A +  +++P+N   D     + +   S +    
Sbjct:   628 RLTHHSAITVLARYASS--LQYENDTSAQVTYVVLPVN---DAYVCEVILPEKSPI-RGA 681

Query:   789 ENMPRIPKDEVRRQYKFNA 807
               MP + K   +R   F A
Sbjct:   682 TGMPAMKKSTAKRYAAFEA 700

 Score = 38 (18.4 bits), Expect = 4.8e-65, Sum P(6) = 4.8e-65
 Identities = 10/37 (27%), Positives = 18/37 (48%)
 Links = 1-4-5-(9)-3-2

Query:   926 RQILVPELMDIHPISATLWNVIAALPSIFYRVNQLLL 962
             R ++  E + I  I A +     A P+I  R++  L+
Sbjct:   989 RSVICIEPLKISAIPAAIAATCLAFPAIISRLDAYLI 1025

 Score = 38 (18.4 bits), Expect = 6.7e-62, Sum P(5) = 6.7e-62
 Identities = 9/35 (25%), Positives = 18/35 (51%)
 Links = 1-4-(10)-3-2

Query:  1241 PTNFPKTIDEEIEELSIGARKKQEIDDNAAKTDVL 1275
             PT FP  + E++E + +      E+  +A + D +
Sbjct:   792 PT-FPIFLGEDVETIVLTVPVNMELQPSADELDYM 825


>sp|Q1DKI1.2|DCL1_COCIM RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease DCL1; Includes: RecName: Full=ATP-dependent
            helicase DCL1
        Length = 1464

 Score = 498 (180.4 bits), Expect = 8.4e-64, Sum P(6) = 8.4e-64
 Identities = 159/507 (31%), Positives = 260/507 (51%)
 Links = (1)-3-5-8-4-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKR----AFF 67
             +PR+YQVEL +KA K N I  L TGSGKT IAVLLLK    Q    +D+  ++    +FF
Sbjct:    98 DPREYQVELFEKAKKDNIIAVLDTGSGKTLIAVLLLKHIIEQEL--IDRSAEKPHRVSFF 155

Query:    68 VVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLD 127
             +V+ V LV QQA  ++ + + +V +  G   + LW+  E  ++ + ++ V+V TA+ L  
Sbjct:   156 LVDSVTLVFQQAAVLQNNINQRVDKFCGAMETDLWNG-ETWERHLAKNMVIVCTAEVLYQ 214

Query:   128 LIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAK 187
              + HA++K+E++ +LIFDE H+A    HPY  I+ D+ L   +   P++ G+TAS + AK
Sbjct:   215 CLLHAFVKMENINLLIFDEAHNAK-KDHPYARIVKDFYLKDGNAKRPKIFGMTASPVDAK 273

Query:   188 VAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTV 247
             +    +++  + LE+ ++S I TAS+L  L +   +P E V              ++D +
Sbjct:   274 M---DVVKAARNLETLLNSQIATASNLSLLRQSVPRPNEEVW-------------SYDRL 317

Query:   248 IEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAA-WRTAQVWEKEL 306
              + F ET  +    + F  DL     R ++     +      LG W A W    VW   L
Sbjct:   318 DQPF-ETRLYKELRSRFG-DL-----RALEKLFTFSLKASSNLGAWCADW----VWSYAL 366

Query:   307 GKIIKSQVLPDKTLRFLNMAKTSM--ITIKRLLEPE--MKKIKSI-EALRPY-VPQRVIR 360
              +    + LP    R    A+T+M  + I +++ PE  +++I+   E +R +      +R
Sbjct:   367 TE----ESLPKLEGR---AARTAMGNLPIAKIVRPEAEIQRIREASEIIRSHKFGDPAVR 419

Query:   361 LFEILETFNPEFQKERMK-LEKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNP 419
               E+L         E +K  E+      I+F +QR+ A  L  +   I +     K + P
Sbjct:   420 P-ELLSPKVRRLHHELLKYFERHTDTKCIVFTEQRHTARILCDLFSRIGT-----KHLRP 473

Query:   420 DYVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFD 479
               ++G   R+ AS       ++Q   +  F + E+NCL ATSV EEG+D+  CNL+++FD
Sbjct:   474 GVLIGV--RSDASGGMNISFRQQVLAVVSFRKGEVNCLFATSVAEEGLDIPDCNLIVRFD 531

Query:   480 RPLDMRSYVQSKGRARRAGSRYVITVE 506
                 +  Y+QS+GRAR   S +   VE
Sbjct:   532 LASTLTQYIQSRGRARHMNSTFAHLVE 558

 Score = 218 (81.8 bits), Expect = 8.4e-64, Sum P(6) = 8.4e-64
 Identities = 68/241 (28%), Positives = 108/241 (44%)
 Links = 1-3-5-8-4-(2)

Query:  1503 ISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVP-SPLLRFIDTPTN 1561
             ++DK+IAD  EALIG   L    N    +       ++  D  + +      R    P  
Sbjct:  1115 LADKTIADVCEALIGACCLLASKNHRFDIAVKAVTALVSSDDHNVLNWEQYSRLYSIPKY 1174

Query:  1562 PNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINN--RVTGCYQRLEFL 1619
               A ++      +     Q+++K+GY FK    L  AFTH SY +   RV  CYQRLEFL
Sbjct:  1175 QTAVVDAA----ELDLAAQVKKKLGYDFKYPKLLRSAFTHPSYPSAWARVP-CYQRLEFL 1229

Query:  1620 GDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYH 1679
             GDA+LD     +++       P  LT+ + A+V+N    S+AV+     H       L  
Sbjct:  1230 GDALLDMACVEHIYHKHPDKDPQWLTEHKMAMVSNKFLGSVAVRLGLHSHLNHFSTSLQS 1289

Query:  1680 MIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDS 1739
              I  +V+       ++    + + +T++             PK + D+ E+  GAI++DS
Sbjct:  1290 QITNYVEEIEAAELESGDPPDAWTLTSDP------------PKCLPDMVEAYIGAIFIDS 1337

Query:  1740 G 1740
             G
Sbjct:  1338 G 1338

 Score = 75 (31.5 bits), Expect = 8.4e-64, Sum P(6) = 8.4e-64
 Identities = 20/52 (38%), Positives = 28/52 (53%)
 Links = 1-(3)-5-8-4-2

Query:   542 YCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLL 593
             +  E++LP  SPI+  IV K P   K  A+ + A E C  L   G LDD+ +
Sbjct:   655 FVCEVVLPEKSPIR-GIVGK-PASKKLIAKQSAAFETCLLLRKHGLLDDHFV 704

 Score = 66 (28.3 bits), Expect = 8.4e-64, Sum P(6) = 8.4e-64
 Identities = 28/84 (33%), Positives = 40/84 (47%)
 Links = 1-3-5-8-(4)-2

Query:  1308 IRQRSEEYVSHIDS--DIGLGVSPCLLLTALTT-SNAAD-------------GMSLERFE 1351
             I  R E Y+  +++  ++ L +SP L L ALT  S+  D             G + ER E
Sbjct:  1005 IISRIESYLIALEACQELDLPISPELALEALTKDSDNTDEHRAQQIHFQRGMGKNYERLE 1064

Query:  1352 TIGDSFLKFATTDYLYHTLLDQHE 1375
              +GD FLK AT+  L+    D  E
Sbjct:  1065 FLGDCFLKMATSISLFAMNPDNDE 1088

 Score = 55 (24.4 bits), Expect = 8.4e-64, Sum P(6) = 8.4e-64
 Identities = 44/218 (20%), Positives = 88/218 (40%)
 Links = 1-3-(5)-8-4-2

Query:   687 LSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKT--TVTAAQLQEIQLFHNYLFTQVLQMCK 744
             L+ +++P  P FP++L + +++  +I +   +   V++  L+ +  F   +F  +     
Sbjct:   772 LTREKLPHFPEFPLYL-EDDIECDVICSSISSGFQVSSHDLEVLTTFTLRIFQDIFHKVY 830

Query:   745 TGNLEFDGTSNAPLN-TLIVPLNKRKDDMSYTINMKYVSEVVANMENMPRIPKDEVRRQY 803
               ++       APLN +  +  +  +D + + I +++V       +N P IP        
Sbjct:   831 DRDVGMMTYWLAPLNLSCDISSSASRDLLDWGI-LQFV------FDN-PEIPWSSSN--- 879

Query:   804 KFNAEDYKDAIVMPWYRNLEQPVFYYVAEILPEWRPSSKFPDT-----HFETFNEYFIKK 858
               +A  + +  V   Y   +    Y+   I P  RPS   P +     H     +Y +  
Sbjct:   880 --SAAFFANRFV---YDRWDGRYRYFTHGIDPSLRPSDPPPSSMARRRHMGNIMDYCLSL 934

Query:   859 YK------LEIYDQNQSLLDVDFTSTRLNLLQPRIQNQ 890
             +K      LE  D  Q ++  +    R NLL  R   +
Sbjct:   935 FKNARKKFLENCDWTQPVIKAEIIQLRRNLLDKRTNKE 972

 Score = 39 (18.8 bits), Expect = 4.1e-60, Sum P(4) = 4.1e-60
 Identities = 12/49 (24%), Positives = 24/49 (48%)
 Links = 1-(6)-4-2

Query:   957 VNQLLLTDELRETILVKAFGKEKTKLDDNVEWNSLAYATEYEEKQTIIV 1005
             V+ L  +D  R++  V+  G + T     V     A + +YE++ + +V
Sbjct:   596 VDALYESDRNRKSYTVQTTGAKLTYSSSLVVLAHFANSLQYEKETSTVV 644

 Score = 39 (18.8 bits), Expect = 2.0e-58, Sum P(3) = 2.0e-58
 Identities = 7/11 (63%), Positives = 10/11 (90%)
 Links = 1-(7)-2

Query:   574 VALEACRQLHL 584
             +ALEAC++L L
Sbjct:  1014 IALEACQELDL 1024

 Score = 37 (18.1 bits), Expect = 8.4e-64, Sum P(6) = 8.4e-64
 Identities = 9/20 (45%), Positives = 11/20 (55%)
 Links = 1-3-5-(8)-4-2

Query:   965 ELRETILVKAFGKEKTKLDD 984
             +LR  +L K   KEK K  D
Sbjct:   959 QLRRNLLDKRTNKEKIKEGD 978


>sp|A2RAF3.2|DCL1_ASPNC RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease dcl1; Includes: RecName: Full=ATP-dependent
            helicase dcl1
        Length = 1525

 Score = 466 (169.1 bits), Expect = 5.3e-62, Sum P(5) = 5.3e-62
 Identities = 154/501 (30%), Positives = 233/501 (46%)
 Links = (1)-4-5-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKE-YGVQLFAPLDQGGKR-AFFVV 69
             +PR+YQ+EL ++A  +NTI  L TGSGKT IAVLLLK     +L   ++    R AFF+V
Sbjct:   116 DPREYQLELFERAKVQNTIAVLDTGSGKTLIAVLLLKHTLEKELNDRMEGKPHRIAFFLV 175

Query:    70 EKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLI 129
             + V L  QQA  +  +    VG   G   + LW SK   DQ  +++ V+V TA+ L   +
Sbjct:   176 DSVTLAYQQAAVLRNNLDQSVGHFFGAMGTDLW-SKSVWDQHFQKNMVIVCTAEILNQCL 234

Query:   130 RHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKAKVA 189
              ++Y+K+  + +LIFDE HH     HPY  I+ D  L +     PR+ G+TAS I  K  
Sbjct:   235 LNSYIKMSQINILIFDEAHHTK-KDHPYARIIRDSYLEEVYSKRPRIFGMTASPIDTK-- 291

Query:   190 PEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTVIE 249
                ++++  +LE  +DS I T S++  L +   +P E V              +F+ + +
Sbjct:   292 -GDIVDEATRLEKLLDSRIATTSNMSLLRQVARRPVERVW-------------SFNKLEQ 337

Query:   250 IFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELGKI 309
              F  T  + +    F  D+       ++   +       +LG W + R    W + L   
Sbjct:   338 PF-ATSLYKHLEDRFG-DMAC-----LEGIFRFAWQASSELGRWCSDRA---WARALA-- 385

Query:   310 IKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILETFN 369
                 VLP         A +   T   + E   K+I  I      V        E     +
Sbjct:   386 --DDVLPKLEGSVRKTANSE--TSSNVPESAYKEILRITEASEIVKSYAFSSPETFGQLS 441

Query:   370 PEFQKERMKLEK----AEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYVVGA 425
             P+ Q  R +L +          I+F  +RY A  L  + + +        F+ P  ++G 
Sbjct:   442 PKVQVLREELARYFGRQTETKCIVFTQKRYTALILAELFQTLN-----IPFLRPGVLIGV 496

Query:   426 SGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPLDMR 485
                +LA  +     ++Q   L +F   EINCL ATSV EEG+D+  CNLV++FD    + 
Sbjct:   497 RSGDLAGMNIT--FRQQFISLVKFRTGEINCLFATSVAEEGLDIPDCNLVVRFDLYQTLI 554

Query:   486 SYVQSKGRARRAGSRYVITVE 506
              YVQS+GRAR   S Y   VE
Sbjct:   555 QYVQSRGRARHFNSTYASMVE 575

 Score = 220 (82.5 bits), Expect = 5.3e-62, Sum P(5) = 5.3e-62
 Identities = 67/244 (27%), Positives = 112/244 (45%)
 Links = 1-4-5-3-(2)

Query:  1503 ISDKSIADAVEALIGVHLLTLGPNPTLKV-MNWMGLKVIQKDQKSDVPSPLLRFIDTPTN 1561
             +++K+IAD  EALIG  LL+ GP+    + +  +   V     K++     + F   P  
Sbjct:  1171 LAEKTIADVCEALIGAALLSGGPDHRFDMAVKAVTTLVNSPSHKAERWKDYISFYTIPKY 1230

Query:  1562 PNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRV-TGCYQRLEFLG 1620
                + +      + +   ++EEK+ YRF+    L  AFTH SY +      CYQRLEFLG
Sbjct:  1231 QRRAADGA----ELYLSRKIEEKLSYRFRYPTLLGSAFTHPSYPSAWAKVPCYQRLEFLG 1286

Query:  1621 DAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGLYHM 1680
             D+++D +    LF       P  LT+ + A+V+N    +LAVK     H       L   
Sbjct:  1287 DSLIDMVCVEDLFARFPDRDPQWLTEHKMAMVSNKFLGALAVKLGLHTHLKYFSAPLQSQ 1346

Query:  1681 IEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYLDSG 1740
             I ++ +       ++    + + VT +             PK + D+ E+  GA+++DS 
Sbjct:  1347 ITQYAEEIQTAEGESEGAVDYWTVTKDP------------PKCLPDMVEAYVGAVFVDSD 1394

Query:  1741 RNLD 1744
              N +
Sbjct:  1395 FNFE 1398

 Score = 81 (33.6 bits), Expect = 5.3e-62, Sum P(5) = 5.3e-62
 Identities = 24/74 (32%), Positives = 33/74 (44%)
 Links = 1-4-5-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQL 1403
             G + ER E +GD FLK AT+  L+    D  E      R   + N NL+       I + 
Sbjct:  1076 GRNYERLEFLGDCFLKMATSIALFTQNPDDDEFDYHVNRMCLICNKNLFNAAVDKEIYKY 1135

Query:  1404 IVANKFDAHDSWLP 1417
             I +  F  H +W P
Sbjct:  1136 IRSRGFSRH-TWYP 1148

 Score = 71 (30.1 bits), Expect = 5.3e-62, Sum P(5) = 5.3e-62
 Identities = 32/122 (26%), Positives = 52/122 (42%)
 Links = 1-(4)-5-3-2

Query:   474 LVIKFDRPLD---MRSYVQSKGRARRAGSRYVITVEEKDTAAYCSKLPSDI-FTRLVPHN 529
             L+  FD  LD    +       R +  G++          A Y S L  +  F+  V + 
Sbjct:   606 LLYGFDHDLDTVLQKDEGNRTFRIKSTGAKLTYHSATAILARYASSLQYEKEFSAQVTY- 664

Query:   530 QIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELD 589
              ++PI  NG   +  E++LP  SPI+   +  +P   K  A+ + A + C  L     LD
Sbjct:   665 VVLPI--NGA--FVCEVILPEKSPIRG--LTGSPAMKKSIAKRSAAFDTCLLLRKNKLLD 718

Query:   590 DN 591
             D+
Sbjct:   719 DH 720

 Score = 52 (23.4 bits), Expect = 5.3e-62, Sum P(5) = 5.3e-62
 Identities = 12/52 (23%), Positives = 27/52 (51%)
 Links = 1-4-(5)-3-2

Query:   690 KEIPKIPPFPVFLRQGNMKVRLIVAP--KKTTVTAAQLQEIQLFHNYLFTQV 739
             + +P  P FP+FL   +++  +I  P  K+  ++  ++  + +F   +F  V
Sbjct:   793 ERLPHFPEFPIFL-DDDVETTIITTPLEKQLLLSEKEVDALTVFTLRVFRDV 843


>sp|Q09884.1|DCR1_SCHPO RecName: Full=Protein Dicer; AltName: Full=Cell cycle
            control protein dcr1; AltName: Full=RNA interference pathway
            protein dcr1; Includes: RecName: Full=Endoribonuclease dcr1;
            Includes: RecName: Full=ATP-dependent helicase dcr1
        Length = 1374

 Score = 415 (151.1 bits), Expect = 7.7e-61, Sum P(4) = 7.7e-61
 Identities = 147/509 (28%), Positives = 247/509 (48%)
 Links = (1)-4-3-2

Query:    14 RDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKE-YGVQLFAPLD--QGGKRAFFVVE 70
             R YQ ++ + A+K+NT++ + TG+GKT +AV L+K+    Q+       +  K + F+V 
Sbjct:    13 RKYQQDVYNIASKQNTLLVMRTGAGKTLLAVKLIKQKLEEQILIQESNLEHKKISVFLVN 72

Query:    71 KVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLIR 130
             KV LV QQA +I      KVG  +G+ S  +  S++     + +++V+VITA      + 
Sbjct:    73 KVPLVFQQAEYIRSQLPAKVGMFYGELSIEM--SEQLLTNIILKYNVIVITADLFYLFLA 130

Query:   131 HAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYK------LLKKDKPVPRVLGLTASLI 184
               +L I D+ ++IFDECHHA+G+   Y  IM D+       L KK   +PR+ G+TAS  
Sbjct:   131 RGFLSINDLNLIIFDECHHAIGND-AYARIMNDFYHRAKAVLSKKHFTLPRIFGMTASPF 189

Query:   185 KAKVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNF 244
               K     L  +L + E   DS     S+   L+ Y   P E  ++  +     L +P  
Sbjct:   190 TGKKG--NLYHRLYQWEQLFDSKAHVVSEN-ELADYFCLPEESYVMYSNK----LVVPPS 242

Query:   245 DTVIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEK 304
             D++I+  +ET               L   + I  ++KT  A    +G W      QVW  
Sbjct:   243 DSIIKKCEET---------------LQGCKLISRAVKTALAETIDMGLWFG---EQVW-L 283

Query:   305 ELGKIIKSQVLPDKTLRFLNMAKTSMITIKRL-LEPEMKKIKSIEALRPYVPQRVIRLFE 363
              L   ++++ L  K L    ++    + I RL +  E  K        P +P     +F+
Sbjct:   284 YLVDFVETKRLKKKALG-KQLSDDEELAIDRLKIFVEDWKNNKYSDNGPRIP-----VFD 337

Query:   364 ILETFNPEFQK-ERMKL--EKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPD 420
               +  +  F+  E +K    K++ +  +IFV+++  A++L L M+ +    P    +   
Sbjct:   338 STDVTDKVFKLLELLKATYRKSDSVRTVIFVERKATAFTLSLFMKTLNL--PN---IRAH 392

Query:   421 YVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR 480
               +G    +    +     +RQ + L +F   + N LIAT+V EEG+DV  CNLVI+F+ 
Sbjct:   393 SFIGHGPSD--QGEFSMTFRRQKDTLHKFKTGKYNVLIATAVAEEGIDVPSCNLVIRFNI 450

Query:   481 PLDMRSYVQSKGRARRAGSRYVITVEEKD 509
                +  YVQS+GRAR   S+++I +  ++
Sbjct:   451 CRTVTQYVQSRGRARAMASKFLIFLNTEE 479

 Score = 224 (83.9 bits), Expect = 7.7e-61, Sum P(4) = 7.7e-61
 Identities = 81/254 (31%), Positives = 123/254 (48%)
 Links = 1-4-3-(2)

Query:  1501 QHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRFIDTPT 1560
             Q +S K IAD VEA IG  LL  G +  LK+   + + ++      +  +    + D  T
Sbjct:  1015 QKLSVKRIADMVEASIGACLLDSGLDSALKICKSLSVGLLDISNWDEWNN----YFDLNT 1070

Query:  1561 NPNASLNFLNNLWQQFQFTQ-LEEKIGYRFKERAYLVQAFTHASYINNR-VTGCYQRLEF 1618
               ++    L N+  QF ++  +EE IGY FK +  L  AF H S ++ + +   YQ+LEF
Sbjct:  1071 YADS----LRNV--QFPYSSYIEETIGYSFKNKKLLHLAFIHPSMMSQQGIYENYQQLEF 1124

Query:  1619 LGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHF----IAMC 1674
             LGDAVLDY+I +YL++     + G LTD +S  V N   + +       K+      AMC
Sbjct:  1125 LGDAVLDYIIVQYLYKKYPNATSGELTDYKSFYVCNKSLSYIGFVLNLHKYIQHESAAMC 1184

Query:  1675 PGLYH---MIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESV 1731
               ++    +IE F +  SE       N   +      EID         PK + D  E++
Sbjct:  1185 DAIFEYQELIEAFRETASE-------NPWFWF-----EIDS--------PKFISDTLEAM 1224

Query:  1732 AGAIYLDSGRNLDT 1745
               AI+LDSG +L +
Sbjct:  1225 ICAIFLDSGFSLQS 1238

 Score = 118 (46.6 bits), Expect = 7.7e-61, Sum P(4) = 7.7e-61
 Identities = 34/136 (25%), Positives = 61/136 (44%)
 Links = 1-4-(3)-2

Query:  1282 VLPVAINEKSRSFSFEKESKAINGRLIRQRSEEYVSHIDSDIGLGVSPCLLLTALTTSNA 1341
             +LPV+ + K+ +         I   L+   +  ++ H   D  +  + C    ALT++ +
Sbjct:   871 ILPVSRHLKNSALLIPSILYHIENLLV---ASSFIEHFRLDCKIDTA-C---QALTSAES 923

Query:  1342 ADGMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIP 1401
                   +R E  GD FLK   +  ++    D  E +L F R K +SNCNLY++     +P
Sbjct:   924 QLNFDYDRLEFYGDCFLKLGASITVFLKFPDTQEYQLHFNRKKIISNCNLYKVAIDCELP 983

Query:  1402 QLIVANKFDAHDSWLP 1417
             +  ++   +    W P
Sbjct:   984 KYALSTPLEIRH-WCP 998

 Score = 73 (30.8 bits), Expect = 7.7e-61, Sum P(4) = 7.7e-61
 Identities = 32/104 (30%), Positives = 43/104 (41%)
 Links = 1-(4)-3-2

Query:   513 YCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQM 572
             +C+ L  D++TR  P     P        YC E+ LP     K      +P  + + A+ 
Sbjct:   544 FCNTLSRDVYTRYYPTFTAQPCLSGW---YCFEVELP--KACKVPAAQGSPAKSIRKAKQ 598

Query:   573 AVALEACRQLHLEGELDDNLLPKG-RESIAKL--LEHIDEEPDE 613
               A   C  L   G +D +L P   R  IA L  LE  DE  DE
Sbjct:   599 NAAFIMCLDLIRMGLIDKHLKPLDFRRKIADLETLEE-DELKDE 641

 Score = 66 (28.3 bits), Expect = 1.9e-55, Sum P(4) = 1.9e-55
 Identities = 18/51 (35%), Positives = 25/51 (49%)
 Links = 1-4-(5)-2

Query:   919 SVPHSSQ-RQILVPELMDIHPISATLWNVIAALPSIFYRVNQLLLTDELRE 968
             S+P S Q R   + +L  I P+S  L N    +PSI Y +  LL+     E
Sbjct:   854 SIPKSQQVRSFYINDLY-ILPVSRHLKNSALLIPSILYHIENLLVASSFIE 903

 Score = 57 (25.1 bits), Expect = 4.2e-52, Sum P(3) = 4.2e-52
 Identities = 21/72 (29%), Positives = 29/72 (40%)
 Links = 1-(6)-2

Query:  1324 GLGVSPCLLLTALTTSNAADG--MSLERFETIGDSFLKFATTD-YLYHTLLDQHEGKLSF 1380
             G+ V  C L+              S  R   +   FL F  T+  L H  +   E  L F
Sbjct:   436 GIDVPSCNLVIRFNICRTVTQYVQSRGRARAMASKFLIFLNTEELLIHERILHEEKNLKF 495

Query:  1381 ARSKEVSNCNLY 1392
             A S E+SN N++
Sbjct:   496 ALS-ELSNSNIF 506

 Score = 56 (24.8 bits), Expect = 4.5e-59, Sum P(4) = 4.5e-59
 Identities = 19/66 (28%), Positives = 36/66 (54%)
 Links = 1-(7)-3-2

Query:   499 SRYVITVEEKDTA--AYCSKLPSDIFTRLVPHN-QIIPIEENGVTKYCAEL-LLPINSPI 554
             S ++I  ++KD A  A C KLP  +   L  +  + IP  +   + Y  +L +LP++  +
Sbjct:   819 SEFMIPAKKKDKAPSALCKKLPLRLNYSLWGNRAKSIPKSQQVRSFYINDLYILPVSRHL 878

Query:   555 KHAIVL 560
             K++ +L
Sbjct:   879 KNSALL 884


>sp|A1CBC9.2|DCL1_ASPCL RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease dcl1; Includes: RecName: Full=ATP-dependent
            helicase dcl1
        Length = 1534

 Score = 428 (155.7 bits), Expect = 1.2e-60, Sum P(6) = 1.2e-60
 Identities = 151/514 (29%), Positives = 241/514 (46%)
 Links = (1)-4-5-7-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKR---AFFV 68
             +PR+YQ+EL ++A  +NTI  L TGSGKT IAVLLL+   +Q        GK    +FF+
Sbjct:   122 DPREYQIELFERAKAQNTIAVLDTGSGKTLIAVLLLRHV-LQNELNDRANGKPHRVSFFL 180

Query:    69 VEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDL 128
             V+ V L  QQA  +  +    V    G   + LWD ++  ++ ++++ V+V TA+ L   
Sbjct:   181 VDSVTLAYQQAAVLRNNIDQNVAHFFGAMGTDLWD-RQVWEEHLQQNMVIVCTAEILNQC 239

Query:   129 IRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPV-PRVLGLTASLIKAK 187
             + ++++++  + +LIFDE HH     HPY  I+ D    K   P  PR+ G+TAS I  K
Sbjct:   240 LLNSHVRMNQINLLIFDEAHHTK-KDHPYARIIRD-SYFKASPPQRPRIFGMTASPIDTK 297

Query:   188 VAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTV 247
                  ++    +LE+ +DS I T S +  L +  ++P E V     +    L  P F T 
Sbjct:   298 ---GDIIAAATRLETLLDSRIATTSKITLLRQVVSRPIEKV-----WAYDRLESP-FKTN 348

Query:   248 IEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELG 307
             +    E   F N              + ++   +       +LG W + R    W   L 
Sbjct:   349 LHKLMEN-RFGNV-------------KALEGVFRFAWYASSELGRWCSDRA---WLYALA 391

Query:   308 KIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILET 367
                   VLP        +A+++    +R  +   K+I  I+     V        E    
Sbjct:   392 ----DDVLPKLEGHVNKLAESTAAATER--DMAFKEITLIKEASNIVKAHTFNDPEFPGE 445

Query:   368 FNPEFQKERMKLEK----AEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYVV 423
              +P+ +  + +L K    A     IIF  +RY A +L  +   +    P  +   P  ++
Sbjct:   446 LSPKVRLLQTELSKHFSHAPETKCIIFTQKRYTAKTLHELFTILSI--PHLR---PGVLI 500

Query:   424 GASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPLD 483
             G    ++   +     ++Q   L +F + EINCL ATSV EEG+D+  CNLV++FD    
Sbjct:   501 GVRSGDIGGMNIT--FRQQFLALVKFRKGEINCLFATSVAEEGLDIPDCNLVVRFDLYHT 558

Query:   484 MRSYVQSKGRARRAGSRYVITVEEKDTAAYCSKL 517
             +  YVQS+GRAR   S Y   VE KD + + ++L
Sbjct:   559 LIQYVQSRGRARHYHSTYASMVE-KDNSDHEARL 591

 Score = 244 (91.0 bits), Expect = 1.2e-60, Sum P(6) = 1.2e-60
 Identities = 85/261 (32%), Positives = 122/261 (46%)
 Links = 1-4-5-7-3-(2)

Query:  1497 LLTQ-QH-ISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQK--DQKSDVPSPL 1552
             +L+Q +H + +K+IAD  EALIG  LL+ GP         MG+K +    D  S   S  
Sbjct:  1170 MLSQAKHALGEKTIADVCEALIGACLLSGGPEHRFD----MGVKAVSVFVDSPSHAVSRW 1225

Query:  1553 LRFIDTPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINN---RV 1609
               +I     PN  +             Q+EEK+GY F+    L  A TH S  +    RV
Sbjct:  1226 KEYIGLYKPPNYQVRKAEGAETNLAL-QVEEKLGYHFRYPRLLCSAVTHPSTPSTWYFRV 1284

Query:  1610 TGCYQRLEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKH 1669
               CYQRLEFLGD++LD +    LF       P  LT+ + A+V+N    +LAVK  F KH
Sbjct:  1285 P-CYQRLEFLGDSLLDMVCVEDLFHRFPDRDPQWLTEHKMAMVSNKFLGALAVKLGFHKH 1343

Query:  1670 FIAMCPGLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFE 1729
               A    L   I  +V+       ++   A  Y V  ++            PK + D+ E
Sbjct:  1344 IKAFSNPLQAQITYYVEEIETAEAESE-GAVDYWVVAKDP-----------PKCLPDMVE 1391

Query:  1730 SVAGAIYLDSGRNLDTTWQVI 1750
             +  GAI++DS    D +++VI
Sbjct:  1392 AYLGAIFVDS----DFSFEVI 1408

 Score = 93 (37.8 bits), Expect = 1.2e-60, Sum P(6) = 1.2e-60
 Identities = 26/74 (35%), Positives = 34/74 (45%)
 Links = 1-4-5-7-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQL 1403
             G + ER E +GD FLK AT+  L+    D  E      R   + N NL+   KK  I + 
Sbjct:  1083 GKNYERLEFLGDCFLKMATSIALFTQNPDDDEFDYHVNRMCLICNKNLFNTAKKRQIYRY 1142

Query:  1404 IVANKFDAHDSWLP 1417
             I +  F  H  W P
Sbjct:  1143 IRSRSFSRH-VWYP 1155

 Score = 66 (28.3 bits), Expect = 1.2e-60, Sum P(6) = 1.2e-60
 Identities = 31/113 (27%), Positives = 48/113 (42%)
 Links = 1-(4)-5-7-3-2

Query:   483 DMRSYVQ-SKGR----ARRAGSRYVITVEEKDTAAYCSKLPSDIFTRLVPHNQIIPIEEN 537
             D+ S +Q  +GR     +  G+R          A Y S L  +  T   P    + ++  
Sbjct:   620 DLDSLLQHEEGRRTFTVKSTGARLTYHSAIAILARYASSLQYEKET--TPQATYV-VQSV 676

Query:   538 GVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDD 590
             G T  C E++LP  SPI+   +  +P   K  A+ + A + C  L     LDD
Sbjct:   677 GNTYVC-EVILPEKSPIRG--LTGSPAIRKSIAKQSAAFDTCLLLRRHKLLDD 726

 Score = 50 (22.7 bits), Expect = 1.2e-60, Sum P(6) = 1.2e-60
 Identities = 12/55 (21%), Positives = 31/55 (56%)
 Links = 1-4-(5)-7-3-2

Query:   687 LSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKT--TVTAAQLQEIQLFHNYLFTQV 739
             L+ +++P  P FP++L + +++ +++     T   ++A +L+ +  F   +F  V
Sbjct:   797 LTREKLPDFPAFPIYLDE-DIETKVVPRSLDTGMELSAEELRALTTFTLRIFRDV 850

 Score = 45 (20.9 bits), Expect = 4.1e-54, Sum P(3) = 4.1e-54
 Identities = 39/168 (23%), Positives = 66/168 (39%)
 Links = 1-(6)-2

Query:  1232 QENQEDENTPTNFPKTIDEEIEELSIGARKKQEID-----DNAAKTDVLERENCEVL--- 1283
             +E +E E T  NF +T+ E+   +  G     ++D     +   +T  ++     +    
Sbjct:   592 REVREAEKTMQNFCETLPED--RILHG--NDHDLDSLLQHEEGRRTFTVKSTGARLTYHS 647

Query:  1284 PVAINEK-SRSFSFEKESKAINGRLIRQRSEEYVSHI----DSDI-GLGVSPCLLLTALT 1337
              +AI  + + S  +EKE+      +++     YV  +     S I GL  SP +  +   
Sbjct:   648 AIAILARYASSLQYEKETTPQATYVVQSVGNTYVCEVILPEKSPIRGLTGSPAIRKSIAK 707

Query:  1338 TSNAADGMSLERFETIGDSFLKFATTDYLYHTLLD-QHEGKLSFARSK 1384
              S A D   L R   + D F K      +YH  L      KL+    K
Sbjct:   708 QSAAFDTCLLLRRHKLLDDFFKS-----IYHKRLPAMRNAKLAITSKK 750

 Score = 44 (20.5 bits), Expect = 1.2e-60, Sum P(6) = 1.2e-60
 Identities = 17/61 (27%), Positives = 30/61 (49%)
 Links = 1-4-5-(7)-3-2

Query:   932 ELMDIHPISATLWNVIAALPSIFYRVNQLLLT----DELRETILVKAFGKEK-TKLDDNV 986
             E + I  I  ++ +   A P+I  R++  L++    DEL + ++   +  E  TK  DN 
Sbjct:  1010 EPLKISAIPPSIASTCLAFPAIITRLDSYLISIEACDEL-DLVIRSDYALEAVTKDSDNT 1068

Query:   987 E 987
             E
Sbjct:  1069 E 1069

 Score = 39 (18.8 bits), Expect = 6.9e-58, Sum P(4) = 6.9e-58
 Identities = 19/76 (25%), Positives = 31/76 (40%)
 Links = 1-(8)-3-2

Query:   933 LMDIHPISATLWNVIAALPS--IFYR----VNQLLLTDELRETILVKAFGKEKTKLDDNV 986
             L ++     T+ N    LP   I +     ++ LL  +E R T  VK+ G   T      
Sbjct:   591 LREVREAEKTMQNFCETLPEDRILHGNDHDLDSLLQHEEGRRTFTVKSTGARLTYHSAIA 650

Query:   987 EWNSLAYATEYEEKQT 1002
                  A + +YE++ T
Sbjct:   651 ILARYASSLQYEKETT 666


>sp|A1DE13.1|DCL1_NEOFI RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease dcl1; Includes: RecName: Full=ATP-dependent
            helicase dcl1
        Length = 1538

 Score = 457 (165.9 bits), Expect = 1.6e-60, Sum P(6) = 1.6e-60
 Identities = 157/517 (30%), Positives = 237/517 (45%)
 Links = (1)-4-6-5-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQ--GGKR---AF 66
             +PR+YQ+EL ++A  +NTI  L TGSGKT IAVLLL+     +   LD    GK    +F
Sbjct:   126 DPREYQIELFERAKTQNTIAVLDTGSGKTLIAVLLLRH---TILNELDNRANGKPHRVSF 182

Query:    67 FVVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLL 126
             F+V+ V L  QQA  +  +    V    G   + LWD K   D+ ++R+ V+V TA+ L 
Sbjct:   183 FLVDSVTLAYQQAAVLRNNIDQNVAHFFGAMGTDLWD-KRTWDEHLQRNMVIVCTAEILN 241

Query:   127 DLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKA 186
               + ++Y+K++ + +LIFDE HHA    HPY  I+ D     +    PRV G+TAS I  
Sbjct:   242 QCLLNSYVKMDQINLLIFDEAHHAK-KDHPYARIIRDSYFKAQPSQRPRVFGMTASPIDT 300

Query:   187 KVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDT 246
             K     + E   +LE+ +DS I T S +  L +  ++P E V     +    L  P    
Sbjct:   301 K---GDITEAATRLETLLDSRIATTSKITLLREVVSRPIEKV-----WAYNRLESPFATE 352

Query:   247 VIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKEL 306
             + ++ D     +                 ++   +       +LG W + R    W   L
Sbjct:   353 LYKLMDTRYGNIKV---------------LEGVYRFAWHASSELGKWCSDRA---WWHAL 394

Query:   307 GKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILE 366
                    VLP        + +++ +  +       K I  I      V        E+  
Sbjct:   395 A----DDVLPKLEGNISKLVESNTLNAEH--GAVFKDIIRIREASETVKNYSFADPELPG 448

Query:   367 TFNPEFQKERMKLEKAEHLS------AIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPD 420
               +P+ Q  RM+L K  H S       I+F  +RY A  L  +   +    P  +   P 
Sbjct:   449 ELSPKVQLLRMELSK--HFSDTTGTKCIVFTQKRYTAKILNELFTVLNI--PHLR---PG 501

Query:   421 YVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR 480
              ++G    ++   +     ++Q   L +F   EINCL ATSV EEG+D+  CNLV++FD 
Sbjct:   502 VLIGVRPGDIGGMNVT--FRQQFLALVKFRTGEINCLFATSVAEEGLDIPDCNLVVRFDL 559

Query:   481 PLDMRSYVQSKGRARRAGSRYVITVEEKDTAAYCSKL 517
                +  YVQS+GRAR   S Y I VE KD A +  +L
Sbjct:   560 YRTLIQYVQSRGRARHCTSTYAIMVE-KDNAEHEGRL 595

 Score = 210 (79.0 bits), Expect = 1.6e-60, Sum P(6) = 1.6e-60
 Identities = 74/248 (29%), Positives = 111/248 (44%)
 Links = 1-4-6-5-3-(2)

Query:  1497 LLTQ-QH-ISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLR 1554
             LL++ +H + +K+IAD  EALIG  LL+ GP     +       ++  D  S   S    
Sbjct:  1174 LLSEGKHALGEKTIADVCEALIGASLLSGGPENRFDMATKAVTALV--DSPSHRVSCWKE 1231

Query:  1555 FIDTPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINN---RVTG 1611
             +I   T P                  +EE++GY F     L  A TH S  +    RV  
Sbjct:  1232 YITLYTMPKYQTEKPRGSEDDLA-RHVEEELGYHFTYPRLLASAITHPSLPSTWGYRVP- 1289

Query:  1612 CYQRLEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFI 1671
             CYQRLEFLGD++LD +    LF       P  LT+ + A+V+N    +L+VK  F +  +
Sbjct:  1290 CYQRLEFLGDSLLDMVCVEDLFRRFPDRDPQWLTEHKMAMVSNKFLGALSVKLGFHRRIM 1349

Query:  1672 AMCPGLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESV 1731
             A    L   I  +V+       ++   A  Y V  ++            PK + D+ E+ 
Sbjct:  1350 AFSNPLQAQITHYVEEIESAQAESR-GAVDYWVVAKDP-----------PKCLPDMVEAY 1397

Query:  1732 AGAIYLDS 1739
              GAI++DS
Sbjct:  1398 LGAIFVDS 1405

 Score = 87 (35.7 bits), Expect = 1.6e-60, Sum P(6) = 1.6e-60
 Identities = 26/74 (35%), Positives = 33/74 (44%)
 Links = 1-4-6-5-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQL 1403
             G + ER E +GD FLK AT+  LY    D  E      R   + N NL+    K  I + 
Sbjct:  1087 GKNYERLEFLGDCFLKMATSIALYTQNPDDDEFDYHVNRMCLICNKNLFNTAIKKQIYRY 1146

Query:  1404 IVANKFDAHDSWLP 1417
             I +  F  H  W P
Sbjct:  1147 IRSRGFSRH-IWYP 1159

 Score = 65 (27.9 bits), Expect = 1.6e-60, Sum P(6) = 1.6e-60
 Identities = 24/80 (30%), Positives = 36/80 (45%)
 Links = 1-(4)-6-5-3-2

Query:   511 AAYCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTA 570
             A Y S L  +  T  VP  Q+  +  +    Y  E++LP  SPI+   +  +P   K  A
Sbjct:   657 ARYASSLQYEKET--VP--QVTYVVGHVSNAYVCEVILPEKSPIRG--LTGSPAIRKAVA 710

Query:   571 QMAVALEACRQLHLEGELDD 590
             + + A + C  L     LDD
Sbjct:   711 KQSAAFDTCLLLRKHRLLDD 730

 Score = 52 (23.4 bits), Expect = 1.6e-60, Sum P(6) = 1.6e-60
 Identities = 35/136 (25%), Positives = 48/136 (35%)
 Links = 1-4-6-(5)-3-2

Query:  1108 GAWSGSESIVPSGWGDWDGPE--PDNSPMPFQILGGPGGLNVQALMADV--GRVFDPSTA 1163
             G  SG+    P  W DWD      +N  +PF     P  L V   + D   GR F   T 
Sbjct:   878 GPGSGTN---PRDWTDWDTVSFVHNNDEIPFTRDLNPDSL-VNRFIFDNWDGR-FRYFTV 932

Query:  1164 SSSLSQTVQESTVSPPKQLTKEEEQFKKLQNDLLKQAKERLEALEMSEDMEKPRRLEDTV 1223
             +  ++ T+Q S   PP            + N  L  +K          D  +P    + V
Sbjct:   933 A--VADTLQPSDPPPPS--VPRRRHMNNIMNYTLSLSKNSRARFFSGCDWNQPVLQAELV 988

Query:  1224 NLE-DYGDDQENQEDE 1238
              L  +  D    QE E
Sbjct:   989 RLRRNLLDKMTTQEKE 1004

 Score = 51 (23.0 bits), Expect = 1.6e-60, Sum P(6) = 1.6e-60
 Identities = 11/55 (20%), Positives = 31/55 (56%)
 Links = 1-4-(6)-5-3-2

Query:   687 LSAKEIPKIPPFPVFLRQGNMKVRLIVAPKK--TTVTAAQLQEIQLFHNYLFTQV 739
             L+ +++P+ P F ++L + +++ +++  P K    ++  +LQ +  F   +F  +
Sbjct:   801 LTREKLPEFPAFSIYLDE-DVETKVLSYPLKHGLQISVDELQSLTTFTLRIFRDI 854

 Score = 46 (21.3 bits), Expect = 5.2e-60, Sum P(6) = 5.2e-60
 Identities = 16/48 (33%), Positives = 24/48 (50%)
 Links = 1-4-(7)-5-3-2

Query:   824 QPVFYYVAEILPEWRPSSKFPDTHFETFNEYFIKKYKLEI-YDQNQSL 870
             +P+     E LPE+   S + D   ET    +  K+ L+I  D+ QSL
Sbjct:   796 RPILLLTREKLPEFPAFSIYLDEDVETKVLSYPLKHGLQISVDELQSL 843

 Score = 39 (18.8 bits), Expect = 7.3e-57, Sum P(4) = 7.3e-57
 Identities = 17/46 (36%), Positives = 22/46 (47%)
 Links = 1-(8)-3-2

Query:   543 CAELLLPIN-SPIKHAIV---LKNPMPNKKTAQMAVALEACRQLHL 584
             CAE   P+  S I  +IV   L  P    +     +ALEAC +L L
Sbjct:  1012 CAE---PLRISAIPTSIVSTCLAFPAIISRLDSYLIALEACDELEL 1054


>sp|Q2VF19.1|DCL1_CRYPA RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease DCL-1; Includes: RecName: Full=ATP-dependent
            helicase DCL-1
        Length = 1548

 Score = 465 (168.7 bits), Expect = 4.2e-60, Sum P(4) = 4.2e-60
 Identities = 146/501 (29%), Positives = 246/501 (49%)
 Links = (1)-4-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKR--AFFVV 69
             +PRDYQ+EL ++A ++NTI  L TGSGKT IA LLL     Q      +G  R  AFF+V
Sbjct:    98 SPRDYQMELFERAKQQNTIAVLDTGSGKTLIAALLLDHTVNQELEDRAKGLPRRIAFFLV 157

Query:    70 EKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLI 129
             EKV L  QQ   +E + +  V    G++    W +K   +  +  H V+V TA+ L   +
Sbjct:   158 EKVALAFQQHAVLECNLAHSVAVFSGESIKNTW-TKGFWETQLADHEVIVCTAEILNQCL 216

Query:   130 RHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPV--PRVLGLTASLIKAK 187
             ++AY++I+ + +L+FDE HH     HPY  I+ DY    KD+ +  PR+ G+TAS + A 
Sbjct:   217 QYAYIRIDQINLLVFDEAHHTK-KNHPYARIIKDYYASGKDRGLRLPRIFGMTASPVDAL 275

Query:   188 VAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTV 247
             +    + +   +LE  + S I T +D  +L +   +P + +I              ++ +
Sbjct:   276 I---DVRQAAIELEGLLHSRIATTADPDALRRAVGRPKKEIIY------------KYNPL 320

Query:   248 IEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKELG 307
             ++     + F     +  P L +   +    +   + A  R+LG W   R  Q++ ++  
Sbjct:   321 VKPIQTMLTF-----KLRP-L-IANNKQFSKAFAFSEAAARELGTWFVDRMWQLFLED-E 372

Query:   308 KIIKSQVLPDKTLRFLNMAKTSMITIKR-LLEPEMKKIKSIEALRPYVPQRVIRLFEILE 366
             +++K +   +++L   +MA   ++   R  +    + I+S E  +P  P  +    + L 
Sbjct:   373 ELLKLEAKTERSLS-KDMAAPEVVEKHRNAVRSARELIRSHEFPKPE-PGLLSSKLKTLS 430

Query:   367 TFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYVVGA- 425
                 E+  +         +  I+FV++R+ A    L+    +S   +     P   VG+ 
Sbjct:   431 KLLEEYFTD-------SSIRCIVFVERRWTAK---LLTDFFESHAAEI----PGLKVGSL 476

Query:   426 SGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPLDMR 485
              G N     SQ   + Q   +  F +   NC+ ATSV EEG+D+  CNL+I+FD    M 
Sbjct:   477 MGANAEGGSSQTSFREQIRTILSFKKGNTNCIFATSVAEEGLDIPDCNLIIRFDICKTMI 536

Query:   486 SYVQSKGRARRAGSRYVITVE 506
              Y+QS+GRAR+A S Y+  +E
Sbjct:   537 QYIQSRGRARQADSTYIHLIE 557

 Score = 204 (76.9 bits), Expect = 4.2e-60, Sum P(4) = 4.2e-60
 Identities = 72/260 (27%), Positives = 111/260 (42%)
 Links = 1-4-3-(2)

Query:  1498 LTQQHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRFID 1557
             + +  ++DKSIAD  EALIG   +T   +    +      +++   Q      P+ ++ D
Sbjct:  1171 MDEHRLADKSIADVCEALIGAAYMTTRKHDDYDLAVRAVTRLVNHKQH-----PMTKWDD 1225

Query:  1558 ---TPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHAS--YINNRVTGC 1612
                    P        N  +     ++ E  GY+FK    L  AF H S  Y+ ++V   
Sbjct:  1226 YHAAYVMPGWQ-TMPANAAELDMAQKIHEATGYQFKHPRVLRSAFRHPSRPYVFDKVPH- 1283

Query:  1613 YQRLEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIA 1672
             YQRLEFLGDA+ D     YLF  +    P  LT+ + A+V+N     LAV   F K  + 
Sbjct:  1284 YQRLEFLGDALFDMACVDYLFHIAPDEGPQWLTEHKMAMVSNQFLGCLAVSLGFHKFILH 1343

Query:  1673 MCPGLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVA 1732
                 +   I ++V   +E        AE           +   E  + PK + D+ E+  
Sbjct:  1344 HHASIGSQIHEYVTEITEARRAAEDAAEAAGKPRSAYSRDYWVEAPQPPKCIPDVLEAYV 1403

Query:  1733 GAIYLDSGRNLDTTWQVIFH 1752
             GAI++DS  +     Q  FH
Sbjct:  1404 GAIFVDSKYDYSVVQQ-FFH 1422

 Score = 90 (36.7 bits), Expect = 4.2e-60, Sum P(4) = 4.2e-60
 Identities = 24/76 (31%), Positives = 39/76 (51%)
 Links = 1-4-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKK--LGIP 1401
             G + ER E +GDSFLK ATT  ++  + ++ E      R   + N NL+ + K   L + 
Sbjct:  1080 GANYERLELLGDSFLKMATTIAVFTLIPNKDEFDYHCERMVMICNQNLFGVAKSDDLKLH 1139

Query:  1402 QLIVANKFDAHDSWLP 1417
             + I +  F+   +W P
Sbjct:  1140 EYIRSKSFE-RGTWYP 1154

 Score = 65 (27.9 bits), Expect = 4.2e-60, Sum P(4) = 4.2e-60
 Identities = 28/102 (27%), Positives = 48/102 (47%)
 Links = 1-(4)-3-2

Query:   529 NQIIPIEENGVTKYCAELLLPIN-SPIKHAIV-LKNPMPN--KKTAQMAVALEACR--QL 582
             N +  I E     +C  +L P+  SP+   +V +   +P+   +  Q  +AL+ACR  QL
Sbjct:   981 NFLADINETSKNPFCYFVLEPMRISPLPVDVVAMAYLLPSIIHRIEQNLIALDACRLLQL 1040

Query:   583 HLEGELDDNLLPKGRESIAKLLEHIDE----EPDEYAPGIAA 620
              +  +L    L K  ++  +  E +D     EP  + PG+ A
Sbjct:  1041 DIHPDLALEALTKDSDNQGED-ERMDSIQAFEPVNFQPGMGA 1081

 Score = 64 (27.6 bits), Expect = 7.1e-60, Sum P(5) = 7.1e-60
 Identities = 18/54 (33%), Positives = 28/54 (51%)
 Links = 1-(5)-6-3-2

Query:   542 YCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPK 595
             +  E+++P  SP+  AI        K+ A+ + A E C QL  +  LDD+L  K
Sbjct:   660 FICEVMMPPLSPVTSAI--GKVYSTKQVAKCSAAFELCFQLIQKKFLDDHLRSK 711

 Score = 47 (21.6 bits), Expect = 7.1e-60, Sum P(5) = 7.1e-60
 Identities = 14/39 (35%), Positives = 20/39 (51%)
 Links = 1-5-(6)-3-2

Query:   930 VPELMDIHPISATLWNVIAALPSIFYRVNQ-LLLTDELR 967
             V E M I P+   +  +   LPSI +R+ Q L+  D  R
Sbjct:   998 VLEPMRISPLPVDVVAMAYLLPSIIHRIEQNLIALDACR 1036


>sp|Q0UI93.2|DCL1_PHANO RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease DCL1; Includes: RecName: Full=ATP-dependent
            helicase DCL1
        Length = 1522

 Score = 490 (177.5 bits), Expect = 3.8e-59, Sum P(5) = 3.8e-59
 Identities = 162/507 (31%), Positives = 253/507 (49%)
 Links = (1)-4-5-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQG--GKRAFFVV 69
             NPRDYQ+EL  +A  +NTI  L TG+GKT IA LLL+    +      +G   K AFF+V
Sbjct:    68 NPRDYQMELFLRAKMQNTIAVLDTGTGKTHIATLLLRHVLEEELENRAKGCAHKMAFFLV 127

Query:    70 EKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLI 129
             + VNLV QQA  +       V  + G     L+  K+  D+    + V+V TAQ L+D +
Sbjct:   128 DSVNLVFQQANVLRCGLDQGVEGISGAMGQSLFQ-KQTWDKLFAVNMVIVCTAQVLVDCM 186

Query:   130 RHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPV-PRVLGLTASLIKAK- 187
              H+++ I  M +LIFDE HHA  S HPY  +M DY   + D    PR+  +TAS +  K 
Sbjct:   187 MHSFMSISRMNLLIFDEAHHAK-SNHPYARVMKDYYAHELDTSKRPRIFAMTASPVDVKG 245

Query:   188 VAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDTV 247
              + E + E  ++LE+ + S I T SD         +P E V +             +  +
Sbjct:   246 QSAEHVREAARELETLLHSRIATTSDSALARNSITRPEEEVAV-------------YTRL 292

Query:   248 IEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAA---WRTAQVWEK 304
                F ET        ++    D+ P R +     T +    +LG WA+   W  A   E+
Sbjct:   293 RNEF-ETPLHQKVKAKYG---DVAPFRKL---FITAKLHASELGRWASDMYWSFAFADEQ 345

Query:   305 ELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVI--RLF 362
                  I+ ++  +++ R  + A+     + RL E     ++  E   P + ++ +  ++ 
Sbjct:   346 SRKLQIREELKYNRSKRDWSAAELDA-QMARLKEATAF-VQQYEIGAPTLSEQDLSSKVM 403

Query:   363 EILETFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYV 422
             ++    N  +  ER  L +      I+FV++R+ A  L L+  HI    P    ++ D +
Sbjct:   404 KLQYWLNLYY--ERTTLARC-----IVFVEKRHTAQLLKLIFDHIGG--PN---LHCDVL 451

Query:   423 VGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPL 482
             VG + R  A  ++  L + Q   L++F R E+NCL ATSV EEG+D+ QCNLV++FD   
Sbjct:   452 VGINNR--AGEENVSL-RSQILTLQKFRRGELNCLFATSVAEEGLDIPQCNLVVRFDLYR 508

Query:   483 DMRSYVQSKGRARRAGSRYVITVEEKD 509
              M  YVQS+GRAR   S+Y+  +E ++
Sbjct:   509 TMIGYVQSRGRARHRNSKYLHMLEAEN 535

 Score = 183 (69.5 bits), Expect = 3.8e-59, Sum P(5) = 3.8e-59
 Identities = 86/348 (24%), Positives = 140/348 (40%)
 Links = 1-4-5-3-(2)

Query:  1502 HISDKSIADAVEALIGVHLLTLGPNPTLKVMNW-MGLKVIQKDQKSD--VPSPLLRFIDT 1558
             ++ DKS+AD  EA IG   +           +W   +K ++    SD  +      +   
Sbjct:  1144 NLGDKSVADVCEAFIGAAFMQHHKGGQWTPNDWDEAVKAVKLFANSDDHLMEKWTDYYAA 1203

Query:  1559 PTNPNASLNFLNNLWQQFQFT-QLEEKIGYRFKERAYLVQAFTHAS--YINNRVTGCYQR 1615
              T P            Q     ++E K  YRF+    L  AF H S  ++   +   YQR
Sbjct:  1204 YTKPKYQT--AGATATQLDLAHKIEMKHPYRFRYPRLLRSAFIHPSQPFMWENIPS-YQR 1260

Query:  1616 LEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCP 1675
             LEFLGD++LD     +LF       P  LT+ ++ +V+N    ++ VK  +  H      
Sbjct:  1261 LEFLGDSLLDMAFIMHLFYKYPDKDPQWLTEHKTPMVSNKFLGAVCVKLGWHTHMKQNTA 1320

Query:  1676 GLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAI 1735
              L   I  +V    E   + N  A  Y V+  E            PK + D+ E+   AI
Sbjct:  1321 ILSSQIRDYVYEVEEAEREAN-GAVDYWVSVSEP-----------PKCLADVIEAFVAAI 1368

Query:  1736 YLDSGRNLDTTWQVI-FH-------MMRGTIELCCANPPRSPIRELME--FEQSKVRFSK 1785
             ++DS  + +   +    H       M     E   +N P + +  L+   F  S+ R   
Sbjct:  1369 FVDSEFDFNVVQKFFDLHLKPFFLDMTLDAYENFASNHPTTRLSRLLSINFGCSEWRMGA 1428

Query:  1786 ME-RILESGK---VRVTVEVVNNMRFTGMGRNYRIAKATAAKRALKYL 1829
             +E   L  GK   +   V + + + F  +G++ R A+  A+  AL+ L
Sbjct:  1429 LETETLIPGKGKAIAAMVMIHDKVHFHSLGQSGRYARVRASHAALEKL 1476

 Score = 83 (34.3 bits), Expect = 3.8e-59, Sum P(5) = 3.8e-59
 Identities = 39/128 (30%), Positives = 59/128 (46%)
 Links = 1-4-5-(3)-2

Query:  1308 IRQRSEEYVSHIDS-DI-GLGVSPCLLLTALTTS------------NAADGM--SLERFE 1351
             I  R E Y+  +D+ D+  L VSP L L ALT              N   GM  + ER E
Sbjct:   995 IIHRFESYLIALDACDVLDLKVSPALALEALTKDSDNSEEHGEEKINFKSGMGPNYERLE 1054

Query:  1352 TIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYR--LGKKLGIPQLIVANKF 1409
              +GD FLK AT+  ++    +++E +    R   + N NL    +GKK  + + +  + F
Sbjct:  1055 FLGDCFLKVATSLSVFVQQPEENEFEFHVRRMLMLCNQNLMETAVGKKK-LYKYVRTDAF 1113

Query:  1410 DAHDSWLP 1417
                + W P
Sbjct:  1114 SRRN-WYP 1120

 Score = 59 (25.8 bits), Expect = 3.8e-59, Sum P(5) = 3.8e-59
 Identities = 25/115 (21%), Positives = 56/115 (48%)
 Links = 1-(4)-5-3-2

Query:   535 EENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKT-AQMAVALEACRQLHLEGELDDNLL 593
             + NG   +  E++LP + PI   I +   + ++KT A+ + A + C +L  +  L++ LL
Sbjct:   638 QRNG---FVCEVILPEHCPI---ISMVGQVYSRKTIAKCSAAFKMCIELRRKDHLNEFLL 691

Query:   594 PKGRESIAKLLEHIDEEPDEYAPGIAAKVGSSKRKQLYDKKIARALNESFVEADK 648
             P   + +  +   +    ++     A  +  +  KQ  D  +  +L+ + ++AD+
Sbjct:   692 PTISKYLPAMRNALLAVSEKKKGNYAMVIKPTFWKQDRDT-VPESLHLTIIDADR 745

 Score = 46 (21.3 bits), Expect = 3.8e-59, Sum P(5) = 3.8e-59
 Identities = 40/219 (18%), Positives = 97/219 (44%)
 Links = 1-4-(5)-3-2

Query:   687 LSAKEIPKIPPFPVFL---RQGNMKVRLIVAPKKTTVTAAQLQEIQLFHNYLFTQVLQMC 743
             L+ +  P++P FP++L   R  N+  + +  P   ++T   L+    F   +F  +    
Sbjct:   757 LTRRPFPQLPSFPIYLTDCRPSNIVSQSLHIP--ISLTPELLEMFTRFTLRIFEDIYNKV 814

Query:   744 KTGNLEFDGTSNAPLNTLIVPLNKRKDDMSYTINMKYVSEVVANMENMPRIPKDEVRRQY 803
                  ++D +    ++  ++P+ + +  ++   +M    EV+ +M+ + ++  +     +
Sbjct:   815 ----YDYDVSK---MSYWMLPVIEHR--VASVRSMSNPQEVL-DMDQIRKVYNEPF---W 861

Query:   804 KFNAEDYKDAIVMPWYRN-LEQPVFYYVAEILPEWRPSSKFPDTHFETFNEYFIKKYKLE 862
             K++ +   D ++  ++ + +     YY   + P  +P    P  +    N  F+K   L+
Sbjct:   862 KWSPQSRTDDLIDRYFVDPMNGGRRYYSDRLAPHLKPQDPVP-ANVPRQNHKFMKNI-LD 919

Query:   863 IYDQNQSLLDVDFTSTRLNLLQPRIQNQ--PRRSRTVSN 899
               D ++ +   D T  R +  QP +Q +  P R   ++N
Sbjct:   920 FSD-SKWMKSRDIT--RWHQDQPVLQVEKIPFRRNHLAN 955

 Score = 42 (19.8 bits), Expect = 9.7e-59, Sum P(5) = 9.7e-59
 Identities = 14/53 (26%), Positives = 28/53 (52%)
 Links = 1-4-(6)-3-2

Query:   979 KTKLD-DNVEWNSLAYATEYEEKQTII-VKKIQQLRDLNQKSIEDQERETREN 1029
             K  LD  + +W      T + + Q ++ V+KI   R+ +  ++ED+E++   N
Sbjct:   915 KNILDFSDSKWMKSRDITRWHQDQPVLQVEKIPFRRN-HLANVEDKEKKELAN 966


>sp|Q4WVE3.3|DCL1_ASPFU RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease dcl1; Includes: RecName: Full=ATP-dependent
            helicase dcl1
        Length = 1537

 Score = 466 (169.1 bits), Expect = 4.8e-59, Sum P(6) = 4.8e-59
 Identities = 160/515 (31%), Positives = 241/515 (46%)
 Links = (1)-4-5-7-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQ--GGKR---AF 66
             +PR+YQ+EL ++A  +NTI  L TGSGKT IAVLLL+     +   LD    GK    +F
Sbjct:   125 DPREYQIELFERAKTQNTIAVLDTGSGKTLIAVLLLRH---TILNELDDRANGKTHRVSF 181

Query:    67 FVVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLL 126
             F+V+ V L  QQA  +  +    V    G   + LWD K   D+ ++R+ V+V TA+ L 
Sbjct:   182 FLVDSVTLAYQQAAVLRNNIDQNVAHFFGAMGTDLWD-KRTWDKHLQRNMVIVCTAEILN 240

Query:   127 DLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLTASLIKA 186
               + ++Y++++ + +LIFDE HHA    HPY  I+ D     +    PRV G+TAS I  
Sbjct:   241 QCLLNSYVRMDQINLLIFDEAHHAK-KDHPYARIIRDSYFKAQPSQRPRVFGMTASPIDT 299

Query:   187 KVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDT 246
             K     + E   +LE+ +DS I T S +  L +  ++P E V      E      P F T
Sbjct:   300 K---GDITEAATRLETFLDSRIATTSKITLLREVVSRPIEKVWAYNRLE------PPFAT 350

Query:   247 VIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKEL 306
                   E    ++T    + ++ +     ++   +       +LG W + R    W   L
Sbjct:   351 ------ELYKLMDTR---YGNIKV-----LEGVYRFAWNASSELGKWCSDRA---WWHAL 393

Query:   307 GKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILE 366
                    VLP        + +++  T+K       K I  I      V        E+  
Sbjct:   394 A----DDVLPKLEGNINKLIESN--TMKAEHGAVFKDIIRIREASETVKNYFFTDPELPG 447

Query:   367 TFNPEFQKERMKLEK----AEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYV 422
               +P+ Q+ RM+L K          I+F  +RY A  L  +   +    P  +   P  +
Sbjct:   448 ELSPKVQRLRMELSKHFNDTTGTKCIVFTQKRYTAKILNELFTVLNI--PNLR---PGVL 502

Query:   423 VGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPL 482
             +G    ++   +     ++Q   L +F   EINCL ATSV EEG+D+  CNLVI+FD   
Sbjct:   503 IGVRPGDIGGMNIT--FRQQFLALVKFRTGEINCLFATSVAEEGLDIPDCNLVIRFDLYR 560

Query:   483 DMRSYVQSKGRARRAGSRYVITVEEKDTAAYCSKL 517
              +  YVQS+GRAR   S Y I VE KD A +  +L
Sbjct:   561 TLIQYVQSRGRARHCTSTYAIMVE-KDNAEHEGRL 594

 Score = 205 (77.2 bits), Expect = 4.8e-59, Sum P(6) = 4.8e-59
 Identities = 75/250 (30%), Positives = 111/250 (44%)
 Links = 1-4-5-7-3-(2)

Query:  1497 LLTQ-QH-ISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQK--DQKSDVPSPL 1552
             LL++ +H + +K+IAD  EALIG  LL+ GP         M  K +    D  S   S  
Sbjct:  1173 LLSEGKHALGEKTIADVCEALIGASLLSGGPEHRFD----MATKAVSALVDSPSHRVSCW 1228

Query:  1553 LRFIDTPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINN---RV 1609
               +I   T P                  +EE++GY F     L  A TH S  +    RV
Sbjct:  1229 KEYITLYTLPKYQTEKHRGSEDDLA-RHVEEELGYHFTYPRLLASAITHPSLPSTWGYRV 1287

Query:  1610 TGCYQRLEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKH 1669
               CYQRLEFLGD++LD +    LF       P  L++ + A+V+N    +L+VK  F + 
Sbjct:  1288 P-CYQRLEFLGDSLLDMVCVEDLFRRFPDRDPQWLSEHKMAMVSNKFLGALSVKLGFHRR 1346

Query:  1670 FIAMCPGLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFE 1729
              +A    L   I  +V+       ++   A  Y V  ++            PK + D+ E
Sbjct:  1347 IMAFSNPLQAQITHYVEEIETAQAESQ-GAVDYWVVAKDP-----------PKCLPDMVE 1394

Query:  1730 SVAGAIYLDS 1739
             +  GAI++DS
Sbjct:  1395 AYLGAIFVDS 1404

 Score = 79 (32.9 bits), Expect = 4.8e-59, Sum P(6) = 4.8e-59
 Identities = 24/74 (32%), Positives = 33/74 (44%)
 Links = 1-4-5-7-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQL 1403
             G + ER E +GD FLK AT+  L+    +  E      R   + N NL+    K  I + 
Sbjct:  1086 GKNYERLEFLGDCFLKMATSIALFSQNPNDDEFDYHVNRMCLICNKNLFNTAIKKQIYRY 1145

Query:  1404 IVANKFDAHDSWLP 1417
             I +  F  H  W P
Sbjct:  1146 IRSRGFSRH-IWYP 1158

 Score = 65 (27.9 bits), Expect = 4.8e-59, Sum P(6) = 4.8e-59
 Identities = 30/113 (26%), Positives = 48/113 (42%)
 Links = 1-(4)-5-7-3-2

Query:   483 DMRSYVQSK-GR----ARRAGSRYVITVEEKDTAAYCSKLPSDIFTRLVPH-NQIIPIEE 536
             D+ S++Q + GR     +  G++          A Y S L  +  T  VP    ++ I  
Sbjct:   623 DLDSFLQEEEGRRTFTVKSTGAKLTYHSAIAILARYASSLQYEKET--VPQVTYVVTIAS 680

Query:   537 NGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELD 589
             N    Y  E++LP  SPI+   +  +P   K  A+ + A + C  L     LD
Sbjct:   681 NA---YVCEVILPEKSPIRG--LTGSPAMRKAVAKRSAAFDTCLLLRKNRLLD 728

 Score = 52 (23.4 bits), Expect = 4.8e-59, Sum P(6) = 4.8e-59
 Identities = 11/55 (20%), Positives = 32/55 (58%)
 Links = 1-4-(5)-7-3-2

Query:   687 LSAKEIPKIPPFPVFLRQGNMKVRLIVAPKK--TTVTAAQLQEIQLFHNYLFTQV 739
             L+ +++P+ P F ++L + +++ +++  P K    ++  +LQ + +F   +F  +
Sbjct:   800 LTREKLPEFPAFSIYLDE-DVETKVLSYPLKHGLQISVDKLQSLTVFTLRIFRDI 853

 Score = 45 (20.9 bits), Expect = 2.5e-58, Sum P(6) = 2.5e-58
 Identities = 16/48 (33%), Positives = 24/48 (50%)
 Links = 1-4-(6)-7-3-2

Query:   824 QPVFYYVAEILPEWRPSSKFPDTHFETFNEYFIKKYKLEI-YDQNQSL 870
             +P+     E LPE+   S + D   ET    +  K+ L+I  D+ QSL
Sbjct:   795 RPILLLTREKLPEFPAFSIYLDEDVETKVLSYPLKHGLQISVDKLQSL 842

 Score = 40 (19.1 bits), Expect = 4.8e-59, Sum P(6) = 4.8e-59
 Identities = 10/32 (31%), Positives = 16/32 (50%)
 Links = 1-4-5-(7)-3-2

Query:   865 DQNQSLLDVDFTSTRLNLLQPRIQNQPRRSRT 896
             D NQ +L  +    R NLL  ++  Q +  +T
Sbjct:   976 DWNQPVLQAELVRLRRNLLD-KMTTQEKEMQT 1006

 Score = 39 (18.8 bits), Expect = 1.7e-56, Sum P(4) = 1.7e-56
 Identities = 14/43 (32%), Positives = 19/43 (44%)
 Links = 1-(8)-3-2

Query:   543 CAE-LLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHL 584
             CAE L +    P   +  L  P    +     +ALEAC +L L
Sbjct:  1011 CAEPLRISALPPSIVSTCLAFPAIISRLDSYLIALEACDELEL 1053


>sp|Q2U6C4.2|DCL1_ASPOR RecName: Full=Dicer-like protein 1; Includes: RecName:
            Full=Endoribonuclease dcl1; Includes: RecName: Full=ATP-dependent
            helicase dcl1
        Length = 1523

 Score = 474 (171.9 bits), Expect = 8.5e-58, Sum P(4) = 8.5e-58
 Identities = 196/684 (28%), Positives = 307/684 (44%)
 Links = (1)-4-3-2

Query:    12 NPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQG-GKR---AFF 67
             +PR+YQVEL ++A  +NTI  L TGSGKT IAVLLLK   +Q    +D+  GK    +FF
Sbjct:   115 DPREYQVELFERAKSQNTIAVLDTGSGKTLIAVLLLKHI-IQNEL-IDRANGKPPRISFF 172

Query:    68 VVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLD 127
             +V+ V L  QQA  +  +    V Q  G   + LW SK+  D   + + V+V TA+ L  
Sbjct:   173 LVDSVTLAFQQAAVLRNNLDQNVAQFFGAMGTDLW-SKQTWDHQFENNMVIVCTAEILNQ 231

Query:   128 LIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPV-PRVLGLTASLIKA 186
              + ++Y++++ + +LIFDE HH     HPY  I+ +   LK D    PR+ G+TAS I  
Sbjct:   232 CLLNSYIRMDQINLLIFDEAHHTK-KDHPYARIIRE-SYLKADPTKRPRIFGMTASPIDT 289

Query:   187 KVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLGIPNFDT 246
             K     ++E   KLE  +DS I T S    L +   +P E     + +E   L  P F T
Sbjct:   290 K---GDIIESATKLEVLLDSKIATTSKPNLLREVVRRPIE-----ESWEYDKLD-PPFAT 340

Query:   247 VIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQVWEKEL 306
               +++    A       F    D+   +P+    + T     +LGP  A R    W   L
Sbjct:   341 --KLYQILQA------RFG---DISSLQPV---FRFTLQASSELGPCCADRA---WAYAL 383

Query:   307 GKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIRLFEILE 366
                    VLP   L   N+ K +      + +  +K+I  I+     V         +  
Sbjct:   384 A----DDVLPK--LEG-NVRKLAQSISSPIPQCALKEISRIQEASDIVKNHSFNSPNVPG 436

Query:   367 TFNPEFQKERMKLEKA-EH---LSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPDYV 422
               +P+ Q  R KL K  EH      I+F  +RY A  L  +   ++       ++ P  +
Sbjct:   437 ELSPKVQLLRQKLIKYFEHPTKTKCIVFTQKRYTAKMLFDLFSTLE-----IPYLRPGVL 491

Query:   423 VGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDRPL 482
             +G    ++   +     ++Q   L +F   EINCL ATSV EEG+D+  CNLV++FD   
Sbjct:   492 IGVRSGDIVGMNVS--FRQQFLALVKFRSGEINCLFATSVAEEGLDIPDCNLVVRFDLYN 549

Query:   483 DMRSYVQSKGRARRAGSRYVITVEE--KDTAAY------CSKLPSDIFTRLVPHNQIIPI 534
              +  YVQS+GRAR + S Y   +E    D AA         KL    F   +P ++I+  
Sbjct:   550 TLIQYVQSRGRARHSSSTYASMIERYNADHAARLVEVREAEKLMQS-FCETLPEDRIL-- 606

Query:   535 EENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEA--CRQLHLEGELDDN- 591
               +G+      +L       K   +++     K T   A+A+ A     L  E E     
Sbjct:   607 --HGIDSEIDSILQ--GEEEKRTFIIR-ATGAKLTYHSALAILARYASSLQYEKETSAQA 661

Query:   592 ---LLPKGRESIAKLLEHIDEEPDEYAPGI-AAKVGSSKRKQLYDKKIARALNESFVEAD 647
                +LP+    + +++   ++ P     G+ A+K  ++K+   +D  +   L +  +  D
Sbjct:   662 TYVVLPQNNSFVCEVILP-EKSPVRGLTGVPASKKSAAKQSAAFDTCVL--LRKHKLLDD 718

Query:   648 KECFIYAFELERFREAELTLNPKR 671
                 +Y   L   R A L +   R
Sbjct:   719 HFNSVYHRRLPAMRNARLAITSSR 742

 Score = 204 (76.9 bits), Expect = 8.5e-58, Sum P(4) = 8.5e-58
 Identities = 95/348 (27%), Positives = 153/348 (43%)
 Links = 1-4-3-(2)

Query:  1503 ISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPS-PLLRFIDTPTN 1561
             + +K++AD  EALIG  LL+ G +        M +K +      D P+   L + D  ++
Sbjct:  1169 LREKTVADVCEALIGASLLSGGLHNQFD----MAVKAVTA--VVDSPNHKALCWADYTSS 1222

Query:  1562 ---PNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRV-TGCYQRLE 1617
                P       +  ++     ++EEK+GYRFK    L  AFTH SY +      CYQRLE
Sbjct:  1223 YMLPKYQTQSPDG-YELDLGRKVEEKLGYRFKYPRLLHSAFTHPSYPSTWAKVPCYQRLE 1281

Query:  1618 FLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCPGL 1677
             FLGD++LD +    LF       P  LT+ + A+V+N    +LAVK     H       L
Sbjct:  1282 FLGDSLLDMVCVDDLFYRYPDKDPQWLTEHKMAMVSNKFLGALAVKLGLHTHLRHFSNPL 1341

Query:  1678 YHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAIYL 1737
                I  + +       ++    + ++VT +             PK + D+ E+  GA ++
Sbjct:  1342 QSQITHYAEEIQAAENESQGAVDYWLVTKDP------------PKCLPDMVEAYLGAAFV 1389

Query:  1738 DSG---RNLDTTWQ----VIFHMMRGTIELCCANP-PRSPIRELMEFEQSKVRFS-KMER 1788
             DS    R ++  +Q      FH M  TI    AN  P + ++  +  E     +  K   
Sbjct:  1390 DSDFQFRVVEDFFQRHVKSYFHDM--TIYDTFANKHPTTFLQNRLTNEYGCTNYCLKAGE 1447

Query:  1789 I--LESGKVRVTVEVVNN--MRFTGMGRNYRIAKATAAKRALKYLHQI 1832
             I  ++ G V V   V+ +  +   G   + R AK  A+++AL  L  +
Sbjct:  1448 IPVVDGGTVSVLAAVIVHEVVIAEGTASSGRYAKVKASEKALSVLENM 1495

 Score = 84 (34.6 bits), Expect = 8.5e-58, Sum P(4) = 8.5e-58
 Identities = 24/74 (32%), Positives = 33/74 (44%)
 Links = 1-4-(3)-2

Query:  1344 GMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARSKEVSNCNLYRLGKKLGIPQL 1403
             G + ER E +GD FLK AT+  L+    D  E      R   + N NL+    K  + Q 
Sbjct:  1074 GKNYERLEFLGDCFLKMATSISLFVQNPDDDEFDFHVNRMCLICNKNLFNTALKKELYQY 1133

Query:  1404 IVANKFDAHDSWLP 1417
               +  F  H +W P
Sbjct:  1134 TRSRGFSRH-TWYP 1146

 Score = 39 (18.8 bits), Expect = 8.5e-58, Sum P(4) = 8.5e-58
 Identities = 10/50 (20%), Positives = 22/50 (44%)
 Links = 1-(4)-3-2

Query:   687 LSAKEIPKIPPFPVFLRQGNMKVRLIVAPKKTTVTAAQLQEIQLFHNYLF 736
             L+ + +P  P F +FL   +++  ++V            QE++    + F
Sbjct:   789 LTRERLPDFPSFTIFL-DDDIET-IVVTESVEEALHISSQELEYLSTFTF 836


>sp|Q2UNX5.1|DCL2_ASPOR RecName: Full=Dicer-like protein 2; Includes: RecName:
            Full=Endoribonuclease dcl2; Includes: RecName: Full=ATP-dependent
            helicase dcl2
        Length = 1377

 Score = 396 (144.5 bits), Expect = 1.0e-53, Sum P(5) = 1.0e-53
 Identities = 144/525 (27%), Positives = 243/525 (46%)
 Links = (1)-5-3-2-4

Query:    11 FNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKR--AFFV 68
             + PR YQ E+ + + K+N IV + TG+GKT IA+L +          L+ GG R   +F+
Sbjct:    14 YKPRQYQYEMFEASLKENIIVAMDTGTGKTQIALLRIAHQ-------LEGGGPRKLTWFL 66

Query:    69 VEKVNLVEQQAIHIEVHT-SFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVITAQCLLD 127
                V L  QQ   I  H  + +   + G      W S+   D+ +K   VVV T   L +
Sbjct:    67 TPTVALCLQQYEVIRSHLPAVRACTITGLDKVERWKSQYIWDELLKDKQVVVSTHAVLFE 126

Query:   128 LIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDY--KLLKKD--KPVPRVLGLTAS- 182
              + H +++I  + +LIFDE HH +  +HP   IM+D+    L+K     VP +LGLTAS 
Sbjct:   127 ALTHGFVRISQLGLLIFDEAHHCM-RRHPANMIMLDFYHPTLRKHGRDSVPCILGLTASP 185

Query:   183 LIKAKVAPEKLMEQLKKLESAMDSVIETAS-DLVSLSKYGAKPYEVVIICKDFEIGCLG- 240
             ++++K       +++K LES +DS+ +T       L+ Y  +P  + IICK  + G  G 
Sbjct:   186 VVRSK------SQEMKTLESNLDSICKTPQVHKQELTTYAHRPELLPIICKAIDEGPGGR 239

Query:   241 ----------IPNFDTVIEIFDETVAFVNTTTEFHPDLDLDP--RRPIKDSLKTTRAVFR 288
                         + D   +   +  + +N + E+   +         IK  +  +R +F 
Sbjct:   240 ALQALEHAWDTADIDGDPDAIPQNGSLLNGSGEYKALMVRKTLCNEQIKRFVDRSRHIFA 299

Query:   289 QLGPWAAWRTAQVWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIE 348
             +LG WAA        ++L   I+ Q L   T+ + +  +  +      L     +    +
Sbjct:   300 ELGEWAADYYICTSVEQLRTTIRDQSL---TMDWEDEERAYLSNFLSKLPVAEVQANLAD 356

Query:   349 ALRPYVPQRVIRLFEILETFN-PEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHI 407
                  +  ++  L   L+ F+ PEF             S +IFV QR +  S+L  +  +
Sbjct:   357 PNNFTMSPKLAALINFLDKFDDPEF-------------SGLIFVKQR-VTVSVLARLLSL 402

Query:   408 KSWEPKFKFVNPDYV---VGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLE 464
                + + +F    YV   VG+  +++         K+Q   +  F     N ++ TSVLE
Sbjct:   403 HP-QTRDRFRCAAYVGMSVGSCRQDMVGDWHNA--KKQRGTMDDFRSGRKNLIVTTSVLE 459

Query:   465 EGVDVKQCNLVIKFDRPLDMRSYVQSKGRARRAGSRYVITVEEKD 509
             EG+DV  C +V+ FD+P +++S++Q +GRAR+  S Y I     D
Sbjct:   460 EGIDVTACRVVVCFDKPANLKSFIQRRGRARQQKSTYAIMFSTAD 504

 Score = 196 (74.1 bits), Expect = 1.0e-53, Sum P(5) = 1.0e-53
 Identities = 52/169 (30%), Positives = 88/169 (52%)
 Links = 1-5-3-(2)-4

Query:  1500 QQHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRFIDTP 1559
             ++ +S K +AD +EALIG   L  G +   ++     L  + + Q  D+PS +     T 
Sbjct:  1028 KRQMSAKVLADVIEALIGAAYLD-GGHSKAQICTHCFLPEVNR-QPLDIPSLI-----TQ 1080

Query:  1560 TNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFL 1619
             T    +   + +         L+  +GY FK    L++A TH S  +++ T  YQRLEFL
Sbjct:  1081 TEHGRTARHIID-------GDLQRHLGYTFKNEDLLIEALTHPSCQHDQTTQSYQRLEFL 1133

Query:  1620 GDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQK 1668
             GDA+LD +I   +F+ S + SPG +T ++ A+VN  +     ++F  ++
Sbjct:  1134 GDAILDMVIVPIIFQYSNKISPGDMTLIKHAVVNANLLGFFCMEFSIEQ 1182

 Score = 99 (39.9 bits), Expect = 1.0e-53, Sum P(5) = 1.0e-53
 Identities = 36/155 (23%), Positives = 64/155 (41%)
 Links = 1-5-(3)-2-4

Query:  1264 EIDDNAAKTDVLERENCEVLPVAINEKSRSFSFEKESKAINGRLIRQRSEEYVSHIDSDI 1323
             E +  +AK  ++  E+C V  + ++              +   LI  R     + I  D+
Sbjct:   867 ESEHGSAKVHMVAAESCTVDKLPVSTAIFGLFIPHIVDRLESTLIANR---LCATILCDV 923

Query:  1324 GLGVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSFARS 1383
             G      ++ TA+   +A    + +R+E +GDS LK+  +  L+   L+  EG L+  R+
Sbjct:   924 GFADIQHVI-TAIMAPSAQGVTNYQRYEFLGDSILKYIVSCQLFFQNLNWPEGFLTEGRT 982

Query:  1384 KEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPP 1418
               V N  L R     G+   I+         W+ P
Sbjct:   983 TIVQNPRLTRAALDAGLDSFIITKALTPR-RWIAP 1016

 Score = 65 (27.9 bits), Expect = 1.0e-53, Sum P(5) = 1.0e-53
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Links = 1-5-3-2-(4)

Query:  1722 KAMGDIFESVAGAIYLDSGRNL 1743
             K   DI ESV GAIY+DSG +L
Sbjct:  1257 KFFSDIVESVLGAIYVDSGGDL 1278

 Score = 54 (24.1 bits), Expect = 1.0e-53, Sum P(5) = 1.0e-53
 Identities = 29/111 (26%), Positives = 52/111 (46%)
 Links = 1-(5)-3-2-4

Query:   502 VITVEEKDTAAY--CSKLPSDIFTRLVPHNQIIPIEEN--GVTKYCAELLLP--INSPIK 555
             VIT +   T  Y  C+ LP +   R V +      E++  G+ K    ++LP  ++  ++
Sbjct:   555 VITPDSVVTHLYHFCAVLPEE---RYVDNRPEFSFEKDRQGLIK--GTVILPSCVHPKVR 609

Query:   556 HAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPKGRESIAKLLEH 606
               I  K    +++ A    A +A R L+  G L+D+LLP  +    +  +H
Sbjct:   610 R-IQGKLWWKSERAAVKETAFQAYRALYEFGLLNDHLLPLTKNPEMRPTDH 659

 Score = 41 (19.5 bits), Expect = 2.2e-52, Sum P(5) = 2.2e-52
 Identities = 10/30 (33%), Positives = 14/30 (46%)
 Links = 1-(6)-3-2-4

Query:   828 YYVAEILPEWRPSSKFPDTHFETFNEYFIK 857
             Y+   +LPE R     P+  FE   +  IK
Sbjct:   566 YHFCAVLPEERYVDNRPEFSFEKDRQGLIK 595


>sp|Q4WA22.2|DCL2_ASPFU RecName: Full=Dicer-like protein 2; Includes: RecName:
            Full=Endoribonuclease dcl2; Includes: RecName: Full=ATP-dependent
            helicase dcl2
        Length = 1388

 Score = 369 (135.0 bits), Expect = 1.7e-51, Sum P(5) = 1.7e-51
 Identities = 156/536 (29%), Positives = 255/536 (47%)
 Links = (1)-5-3-2-4

Query:     7 DLQCFNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKRAF 66
             D   + PR+YQ+E+L+ + K+N IV + TGSGKT IAVL +K   + + +P     K  +
Sbjct:    10 DASPYQPRNYQLEMLEASMKENIIVAMDTGSGKTHIAVLRIKAE-LDICSP----DKVVW 64

Query:    67 FVVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGL-----WDSKEQCDQFMKRHHVVVIT 121
             F+   V L  QQ  H EV  S  +  V  +T +GL     W  +   D  +  + V+V T
Sbjct:    65 FLAPTVALCIQQ--H-EVIAS-NLPAVRTRTLTGLDKVELWTDQSIWDAVLNGYRVIVST 120

Query:   122 AQCLLDLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDY--KLLKKDKP--VPRVL 177
                L D + H ++K+  + +LIFDE HH    +H    IM D+    L K  P  VPR++
Sbjct:   121 HAVLADALSHGFVKMSQLALLIFDEAHHCT-RRHAANKIMQDFYHPTLTKSGPAAVPRIM 179

Query:   178 GLTASLIKAKVAPEKLMEQLKKLESAMDSVIETAS-DLVSLSKYGAKPY--EVVIICKD- 233
             GLTAS +      E LM     +ES +D+V  T       L K+  +P+  ++     D 
Sbjct:   180 GLTASPVVRSNHQELLM-----VESNLDAVCRTPRLHRQELLKFTHRPHLQQIWYTPTDP 234

Query:   234 --FEIGCLGIPNFDTVIEIFD-ETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFR-Q 289
               F    L +       E  D     ++    +  P   LD R  +K +L T +   R Q
Sbjct:   235 AGFRSASLTLGALYHAWENLDIGDDPYIQRLRK-SP---LDDRA-LKKALLTGKTYCREQ 289

Query:   290 LGPWAAWRTAQVWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEA 349
             L  +   R+  ++E ELG+      +     +  +  + S ++       E +K   ++ 
Sbjct:   290 LRRFVD-RSRHIFE-ELGEWAAEYYIYASIKQLRDRVRDSYMSGDW---DEAEKAYLVDF 344

Query:   350 LRPYVPQRVIRLFEILET----FNPEFQKERMKLEKAEH--LSAIIFVDQRYIAYSLLLM 403
             L   +P   I  F + +      +P+F+     L+ ++    S +IFV QR +  S +  
Sbjct:   345 LSK-IPTSDIH-FALNDPDGFRISPKFESLLNFLDSSDQREFSGLIFVKQR-VTVSAMTS 401

Query:   404 MRHIKSWEPKFKFVNPDYVVGASGRNLASSDSQG--LHKR-QTEVLRRFHRNEINCLIAT 460
             +  +  +  + +F    YV G S  + AS D  G  L+ + Q + L  F     N +IAT
Sbjct:   402 LLSVHPYTRE-RFRCAAYV-GWSNSS-ASKDILGDLLNMQLQRDTLDDFRSGRKNLIIAT 458

Query:   461 SVLEEGVDVKQCNLVIKFDRPLDMRSYVQSKGRARRAGSRYVITVEEKDTAAYCSK 516
              VLEEG+D+  C++V+ +D+P +++S++Q +GRARR  S + I     DT+A  S+
Sbjct:   459 DVLEEGIDLSACSVVVCYDKPPNLKSFIQRRGRARRKQSTFAIMFPTDDTSADVSR 514

 Score = 178 (67.7 bits), Expect = 1.7e-51, Sum P(5) = 1.7e-51
 Identities = 54/165 (32%), Positives = 86/165 (52%)
 Links = 1-5-3-(2)-4

Query:  1500 QQHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRFIDTP 1559
             ++ +S K +AD VEALIG   +  G + T +         I++     +P   L  +DT 
Sbjct:  1035 KRQMSTKVLADVVEALIGAAYVD-GGHSTAQAC-------IRRF----LPEINLHAVDTR 1082

Query:  1560 TNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQRLEFL 1619
             T   A+ +      +     +L++ IGY F++ + LV+A TH S   +  T  YQRLE+L
Sbjct:  1083 T---AARSVAPESARHMMNDRLKDHIGYTFEDESLLVEALTHPSCDYDSTTQSYQRLEYL 1139

Query:  1620 GDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKF 1664
             GDAVLD +I   +F    Q   G +T ++ A+VN  + A L ++F
Sbjct:  1140 GDAVLDMVIVSAIFNHRIQRPQGDMTKIKHAVVNANLLAFLCMEF 1184

 Score = 116 (45.9 bits), Expect = 1.7e-51, Sum P(5) = 1.7e-51
 Identities = 45/158 (28%), Positives = 69/158 (43%)
 Links = 1-5-(3)-2-4

Query:  1263 QEIDDNAAKTDVLERENCEV--LPVAINEKSRSFSFEKESKAINGRLIRQRSEEYVSHID 1320
             + I D+AAK  ++  E C +  LP  +       S   E   I   LI  R  + +    
Sbjct:   873 EAIPDSAAKNPIVAAEACTIDRLPFTMAIFGLFISAIVEQLEIE--LIATRLRDTILR-- 928

Query:  1321 SDIGLGVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLYHTLLDQHEGKLSF 1380
              D+    S   ++TA++T  A    + +R+E +GDS LKF+ +  L+    + HEG LS 
Sbjct:   929 -DVSFK-STDHIITAISTPLAHRLTNYQRYEFLGDSILKFSVSCQLFFQHPNWHEGYLSE 986

Query:  1381 ARSKEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPP 1418
              R   V N  L +     G+   IV  +  A   W  P
Sbjct:   987 GRDMIVQNPRLAKAALDTGLDAYIVTKRL-ASRKWSAP 1023

 Score = 74 (31.1 bits), Expect = 1.7e-51, Sum P(5) = 1.7e-51
 Identities = 35/126 (27%), Positives = 61/126 (48%)
 Links = 1-5-3-2-(4)

Query:  1718 IEVPKAMGDIFESVAGAIYLDSGRNLDT----TWQV-IFHMMRGTIELCC-ANPPRSPIR 1771
             +   K   DI ESV GAI++DSG NL        Q+ +   +R  ++       PRS ++
Sbjct:  1259 LNADKFFSDIIESVLGAIFVDSGGNLAPCEVFVEQIGLMAYLRRILDHGIDVRHPRSVVQ 1318

Query:  1772 ELMEFEQSKVRFSKMERI-LESG--KVRVTVEVVNNMRFTGMG-RNYRIAKATAAKRALK 1827
             +L +   + ++F  ++R+  E G    + +V++     F   G      A+ TAA  A+K
Sbjct:  1319 QLAK---TNIQFV-LQRVPTEEGGASYQCSVQMEQAELFVVTGCLTAEEAEVTAAVEAIK 1374

Query:  1828 YLHQIE 1833
             +L + E
Sbjct:  1375 FLTRDE 1380

 Score = 53 (23.7 bits), Expect = 1.7e-51, Sum P(5) = 1.7e-51
 Identities = 30/145 (20%), Positives = 61/145 (42%)
 Links = 1-(5)-3-2-4

Query:   513 YCSKLPSDIFTRLVPHNQIIPIEENGVTKYCAELLLP--INSPIKHAIVLKNPMPNKKTA 570
             +C+ LP   +  + P        E+G+ K    ++LP  ++  ++     +     ++ A
Sbjct:   571 FCAVLPPQPYVDMRPVFSF-ETNEDGLLK--GTVILPSCVHPKVRRTEG-RRWWRTERAA 626

Query:   571 QMAVALEACRQLHLEGELDDNLLPKGRESIAKL-----LEHIDEEPDEYAPGIAAKVGSS 625
                 A +A + L+  G ++D+LLP  ++   K      +  I E  ++Y P I      S
Sbjct:   627 MKETAFQAYKSLYEFGLVNDHLLPLTKKPELKTHDLGSMPSILETSEQYDPWIEWAYSWS 686

Query:   626 KRKQLYDKKIARALNESFVEADKEC 650
                 ++  +I   +NE     D+ C
Sbjct:   687 S-PDIHQSRIVVKMNEG--RGDELC 708


Parameters:
  links
  postsw
  -i cele_dcr1.fa
  -i cele_dcr1.fa
  wordmask=seg+xnu
  -d /data/databases/BLAST/swissprot
  -o celedcr1-vs-swissprot.BLASTP
  E=1e-50

  ctxfactor=1.00

  Query                        -----  As Used  -----    -----  Computed  ----
  Frame  MatID Matrix name     Lambda    K       H      Lambda    K       H
   +0      0   BLOSUM62        0.318   0.134   0.390    same    same    same
               Q=9,R=2         0.244   0.0300  0.180     n/a     n/a     n/a

  Query
  Frame  MatID  Length  Eff.Length     E     S W   T  X   E2     S2
   +0      0     1845      1845   9.0e-51  566 3  11 22  0.41    34
                                                     40  0.45    37


Statistics:

  Database:  /data/databases/BLAST/swissprot
   Title:  swissprot
   Posted:  9:42:51 AM PST Dec 14, 2008
   Created:  9:42:51 AM PST Dec 14, 2008
   Format:  XDF-1
   # of letters in database:  132,868,552
   # of sequences in database:  353,658
   # of database sequences satisfying E:  19
  No. of states in DFA:  634 (134 KB)
  Total size of DFA:  1250 KB (2395 KB)
  Time to generate neighborhood:  0.00u 0.00s 0.00t   Elapsed:  00:00:00
  No. of threads or processors used:  4
  Search cpu time:  109.05u 0.35s 109.40t   Elapsed:  00:00:27
  Total cpu time:  109.26u 0.35s 109.61t   Elapsed:  00:00:27
  Start:  Sun Dec 14 09:52:50 2008   End:  Sun Dec 14 09:53:17 2008
