## Source Information for ens_35_segdup_washufilt

### Description

Segmental duplication dataset compiled by seeking homologies within the reference sequence. This data has been filtered to include only intra-chromosomal SegDups of >97% sequence similarity, >10kb long with <5Mb spacing between them.

The data were kindly provided by Xinwei She and Evan Eichler at the University of Washington.

Filtering criteria set by by Jim Lupski and Matthew Hurles.

Reference:
Bailey JA, Gu Z, Clark RA, Reinert K, Samonte RV, Schwartz S, Adams MD, Myers EW, Li PW, Eichler EE (2002) Recent segmental duplications in the human genome. Science 297:1003-7.

Bailey JA, Yavor AM, Massa HF, Trask BJ, Eichler EE (2001) Segmental duplications: organization and impact within the current human genome project assembly. Genome Res 11:1005-17

She X, Jiang Z, Clark RA, Liu G, Cheng Z, Tuzun E, Church DM, Sutton G, Halpern AL, Eichler EE (2004) Shotgun sequence assembly and recent segmental duplications within the human genome. Nature 431:927-30

### Key

Orientation |  |
|  | Red: Pair members in direct orientation
|  | Green: Pair members in inverted orientation
% Identity |  |
|  | Over 99% identity
|  | 97 - 99% identity
Spacing |  |
|  | Less than 100Kb apart
|  | 100Kb - 1Mb apart
|  | 1 - 5Mb apart