## BWA MEM for paired-end end reads

### Description

This tool aligns paired-end reads to selected reference genome using the BWA MEM algorithm. The reads have to be supplied in two fastq formatted files.

- More information: BWA manual

### Parameters

By default, the tool runs the mapping using the default parameters of BWA MEM algorithm. These parameters are intended for, Illumina, 454 or IonTorrent reads files where the length of the reads is more than 70 base pairs. If your data is from PacBio sequencer, you should use the Data source: PacBio subreads setting to switch to parameters suitable for PacBio reads.

### Output

As a result the tool returns a sorted and indexed BAM-formatted alignment, which is ready for viewing in the Chipster genome browser.