BLASTP 2.0.14 [Jun-29-2000]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= CYS1_DICDI
         (351 letters)

Database: /home/peter/blast/data/swissprot
           88,780 sequences; 31,984,247 total letters

Searching......................................................................................................................................................
3 occurrence(s) of pattern in query
  CYS1_DICDI; PATTERN.
 pattern P-E-E-Q at position 23 of query sequence
effective database length=3.2e+07
 pattern probability=8.9e-06
lengthXprobability=2.8e+02

Number of occurrences of pattern in the database is 349
  CYS1_DICDI; PATTERN.
 pattern P-E-E-Q at position 120 of query sequence
effective database length=3.2e+07
 pattern probability=8.9e-06
lengthXprobability=2.8e+02

Number of occurrences of pattern in the database is 349
  CYS1_DICDI; PATTERN.
 pattern P-E-E-Q at position 237 of query sequence
effective database length=3.2e+07
 pattern probability=8.9e-06
lengthXprobability=2.8e+02

Number of occurrences of pattern in the database is 349
done


Results from round 1

                                                                   Score     E
                                                                   (bits)  Value

Significant matches for pattern occurrence 1 at position 23


sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR                  688  0.0
sp|P30957|RYNC_RABIT RYANODINE RECEPTOR, CARDIAC MUSCLE                 8  4.8
sp|Q08862|GTC_RABIT GLUTATHIONE S-TRANSFERASE YC (ALPHA II) (GST...     7  6.0
sp|O95801|TTC4_HUMAN TETRATRICOPEPTIDE REPEAT PROTEIN 4                 7  7.6
sp|P36114|YKZ8_YEAST HYPOTHETICAL 81.8 KDA PROTEIN IN YPT52-DBP7...     7  9.6


Significant matches for pattern occurrence 2 at position 120


sp|P11559|MCRA_METVO METHYL-COENZYME M REDUCTASE ALPHA SUBUNIT         13  0.13
sp|Q49605|MCRA_METKA METHYL-COENZYME M REDUCTASE I ALPHA SUBUNIT...    11  0.43
sp|P81901|FER_PYRIS FERREDOXIN (SEVEN-IRON FERREDOXIN)                 11  0.55
sp|Q58256|MCRX_METJA METHYL-COENZYME M REDUCTASE II ALPHA SUBUNI...    10  1.1
sp|P53203|YG14_YEAST HYPOTHETICAL 52.9 KD PROTEIN IN ERP6-TFG2 I...     8  3.0
sp|P55002|MGP1_MOUSE MICROFIBRIL-ASSOCIATED GLYCOPROTEIN PRECURS...     7  6.0
sp|Q06234|ASH1_XENLA ACHAETE-SCUTE HOMOLOG 1                            7  7.6
sp|P20918|PLMN_MOUSE PLASMINOGEN PRECURSOR [CONTAINS: ANGIOSTATIN]      7  7.6


Significant matches for pattern occurrence 3 at position 237


sp|P49362|GCSB_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] B, ...     9  1.4
sp|P49361|GCSA_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] A, ...     9  1.4
sp|O49852|GCSP_FLATR GLYCINE DEHYDROGENASE [DECARBOXYLATING], MI...     8  4.8
sp|P32767|PDR6_YEAST PLEIOTROPIC DRUG RESISTANCE REGULATORY PROT...     7  6.0
sp|O49850|GCSP_FLAAN GLYCINE DEHYDROGENASE [DECARBOXYLATING], MI...     7  9.6


Significant alignments for pattern occurrence 1 at position 23

>sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR
          Length = 343

 Score =  688 bits (1789), Expect = 0.0
 Identities = 343/351 (97%), Positives = 343/351 (97%), Gaps = 8/351 (2%)

Query:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
pattern 23                        ****
            MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE
Sbjct:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60

Query:  61  ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPP 120
pattern 120                                                            *
            ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 
Sbjct:  61  ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP- 119

Query:  121 EEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 180
pattern 121 ***
               TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE
Sbjct:  120 ---TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176

Query:  181 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQ 240
pattern 237                                                         ****
            CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG    
Sbjct:  177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG---- 232

Query:  241 AKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVG 300
            AKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVG
Sbjct:  233 AKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVG 292

Query:  301 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII
Sbjct:  293 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343


>sp|P30957|RYNC_RABIT RYANODINE RECEPTOR, CARDIAC MUSCLE
          Length = 4969

 Score =  7.8 bits (25), Expect = 4.8
 Identities = 14/39 (35%), Positives = 19/39 (47%)

Query:  23   PEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEE 61
pattern 23   ****
             PEEQ +F E + K  +K   EE     E  +   G+ EE
Sbjct:  4414 PEEQEKFQEQKTKEEEKEEKEETKSEPEKAEGEDGEKEE 4452


>sp|Q08862|GTC_RABIT GLUTATHIONE S-TRANSFERASE YC (ALPHA II) (GST CLASS-ALPHA)
          Length = 221

 Score =  7.4 bits (24), Expect = 6.0
 Identities = 19/67 (28%), Positives = 35/67 (51%), Gaps = 12/67 (17%)

Query:  21  IPPEEQ-SQFLEFQDKFNKKY---------SH-EEYLERFEIFKSNLGKIEEL-NLIAIN 68
pattern 23    ****
            +PPEEQ ++  + +DK   +Y         SH ++YL   ++ K+++  +E L N+  +N
Sbjct:  112 LPPEEQEAKLAQIKDKAKNRYFPAFEKVLKSHGQDYLVGNKLSKADILLVELLYNVEELN 171

Query:  69  HKADTKF 75
              A   F
Sbjct:  172 PGATASF 178


>sp|O95801|TTC4_HUMAN TETRATRICOPEPTIDE REPEAT PROTEIN 4
          Length = 356

 Score =  7.1 bits (23), Expect = 7.6
 Identities = 14/67 (20%), Positives = 32/67 (46%), Gaps = 5/67 (7%)

Query:  23  PEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGK---IEELNLIAINHKADTKFGVNK 79
pattern 23  ****
            PEEQ++   ++D+ N  +  ++Y +    +   L K     +LN +   ++A  ++ +  
Sbjct:  75  PEEQAK--TYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGN 132

Query:  80  FADLSSD 86
            F    +D
Sbjct:  133 FRSALND 139


>sp|P36114|YKZ8_YEAST HYPOTHETICAL 81.8 KDA PROTEIN IN YPT52-DBP7 INTERGENIC REGION
          Length = 725

 Score =  6.8 bits (22), Expect = 9.6
 Identities = 21/99 (21%), Positives = 43/99 (43%), Gaps = 21/99 (21%)

Query:  21  IPPEEQ--SQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN 78
pattern 23    ****
            + PEEQ     L+F ++      H    ER  +  +++G    +N      +   + G+ 
Sbjct:  213 LTPEEQKDKDLLQFAEQI-----HSMRTER--LSGAHIGNSPAIN------RLRGELGLQ 259

Query:  79  KFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINS 117
               DL  +E  ++       + +DD+ ++    DEF++S
Sbjct:  260 AMEDLPEEEITDH------KVLSDDIDLSQATIDEFVHS 292



Significant alignments for pattern occurrence 2 at position 120

>sp|P11559|MCRA_METVO METHYL-COENZYME M REDUCTASE ALPHA SUBUNIT
          Length = 555

 Score = 13.0 bits (40), Expect = 0.13
 Identities = 16/28 (57%), Positives = 18/28 (64%), Gaps = 3/28 (10%)

Query:  99  IFTDDLPVADYLDDEF---INSIPPEEQ 123
pattern 120                         ****
            IFT D  +AD LDD F   IN + PEEQ
Sbjct:  170 IFTGDDELADELDDRFVIDINKLFPEEQ 197


>sp|Q49605|MCRA_METKA METHYL-COENZYME M REDUCTASE I ALPHA SUBUNIT (MCR I ALPHA)
          Length = 553

 Score = 11.2 bits (35), Expect = 0.43
 Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 3/28 (10%)

Query:  99  IFTDDLPVADYLDDEFINSIP---PEEQ 123
pattern 120                         ****
            I T DL +AD +DD+F+  I    PEEQ
Sbjct:  168 IITGDLELADEIDDKFLIDIEKLFPEEQ 195


>sp|P81901|FER_PYRIS FERREDOXIN (SEVEN-IRON FERREDOXIN)
          Length = 101

 Score = 10.9 bits (34), Expect = 0.55
 Identities = 12/23 (52%), Positives = 16/23 (69%), Gaps = 1/23 (4%)

Query:  114 FINSIPPEEQTAF-DWRTRGAVT 135
pattern 120       ****
            F  S+ PEEQ AF +W+TR  +T
Sbjct:  78  FGKSLTPEEQRAFEEWKTRYGIT 100


>sp|Q58256|MCRX_METJA METHYL-COENZYME M REDUCTASE II ALPHA SUBUNIT (MCR II ALPHA)
          Length = 553

 Score =  9.8 bits (31), Expect = 1.1
 Identities = 14/28 (50%), Positives = 17/28 (60%), Gaps = 3/28 (10%)

Query:  99  IFTDDLPVADYLDDEF---INSIPPEEQ 123
pattern 120                         ****
            IFT D  +AD +D  F   IN + PEEQ
Sbjct:  168 IFTGDDELADEIDKRFLIDINKLFPEEQ 195


>sp|P53203|YG14_YEAST HYPOTHETICAL 52.9 KD PROTEIN IN ERP6-TFG2 INTERGENIC REGION
          Length = 462

 Score =  8.5 bits (27), Expect = 3.0
 Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 9/39 (23%)

Query:  112 DEFINSIP-------PEEQT--AFDWRTRGAVTPVKNQG 141
pattern 120                ****
            DEF+N+ P       PEEQ+  A++W  +  +  + N G
Sbjct:  308 DEFLNTSPSPEVFTLPEEQSGMAWEWHDKDWMLDLTNDG 346


>sp|P55002|MGP1_MOUSE MICROFIBRIL-ASSOCIATED GLYCOPROTEIN PRECURSOR (MAGP) (MAGP-1)
          Length = 183

 Score =  7.4 bits (24), Expect = 6.0
 Identities = 11/37 (29%), Positives = 18/37 (47%)

Query:  100 FTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTP 136
pattern 120                     ****
            + D +  ADY D + ++   PEEQ     + +  V P
Sbjct:  37  YGDQIDNADYYDYQEVSPRTPEEQFQSQQQVQQEVIP 73


>sp|Q06234|ASH1_XENLA ACHAETE-SCUTE HOMOLOG 1
          Length = 199

 Score =  7.1 bits (23), Expect = 7.6
 Identities = 11/27 (40%), Positives = 15/27 (54%), Gaps = 1/27 (3%)

Query:  105 PVADYLDDE-FINSIPPEEQTAFDWRT 130
pattern 120                 ****
            PV+ Y  DE   + + PEEQ   D+ T
Sbjct:  171 PVSSYSSDEGSYDPLSPEEQELLDFTT 197


>sp|P20918|PLMN_MOUSE PLASMINOGEN PRECURSOR [CONTAINS: ANGIOSTATIN]
          Length = 812

 Score =  7.1 bits (23), Expect = 7.6
 Identities = 8/13 (61%), Positives = 11/13 (84%)

Query:  112 DEFINSIPPEEQT 124
pattern 120         ****
            D+  +S+PPEEQT
Sbjct:  359 DQSDSSVPPEEQT 371



Significant alignments for pattern occurrence 3 at position 237

>sp|P49362|GCSB_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] B, MITOCHONDRIAL PRECURSOR
            (GLYCINE DECARBOXYLASE B) (GLYCINE CLEAVAGE SYSTEM
            P-PROTEIN B)
          Length = 1034

 Score =  9.5 bits (30), Expect = 1.4
 Identities = 21/79 (26%), Positives = 39/79 (48%), Gaps = 13/79 (16%)

Query:  231 NSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPN 290
pattern 237       ****
            NSA   PEEQ K++ F   P  +++    I +T P +I  D++++  +  G+ +     +
Sbjct:  80  NSAT--PEEQTKMAEFVGFPNLDSL----IDATVPKSIRLDSMKYSKFDEGLTESQMIAH 133

Query:  291 SLDHGILIVGYSAKNTIFR 309
              D        ++KN IF+
Sbjct:  134 MQD-------LASKNKIFK 145


>sp|P49361|GCSA_FLAPR GLYCINE DEHYDROGENASE [DECARBOXYLATING] A, MITOCHONDRIAL PRECURSOR
            (GLYCINE DECARBOXYLASE A) (GLYCINE CLEAVAGE SYSTEM
            P-PROTEIN A)
          Length = 1037

 Score =  9.5 bits (30), Expect = 1.4
 Identities = 21/79 (26%), Positives = 39/79 (48%), Gaps = 13/79 (16%)

Query:  231 NSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPN 290
pattern 237       ****
            NSA   PEEQ K++ F   P  +++    I +T P +I  D++++  +  G+ +     +
Sbjct:  83  NSAT--PEEQTKMAEFVGFPNLDSL----IDATVPKSIRLDSMKYSKFDEGLTESQMIAH 136

Query:  291 SLDHGILIVGYSAKNTIFR 309
              D        ++KN IF+
Sbjct:  137 MQD-------LASKNKIFK 148


>sp|O49852|GCSP_FLATR GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
            (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
            P-PROTEIN)
          Length = 1034

 Score =  7.8 bits (25), Expect = 4.8
 Identities = 21/79 (26%), Positives = 38/79 (47%), Gaps = 13/79 (16%)

Query:  231 NSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPN 290
pattern 237       ****
            NSA   PEEQ K++ F      +++    I +T P AI  D++++  +  G+ +     +
Sbjct:  80  NSAT--PEEQTKMAEFVGFSNLDSL----IDATVPKAIRLDSMKYSKFDEGLTESQMIAH 133

Query:  291 SLDHGILIVGYSAKNTIFR 309
              D        ++KN IF+
Sbjct:  134 MQD-------LASKNKIFK 145


>sp|P32767|PDR6_YEAST PLEIOTROPIC DRUG RESISTANCE REGULATORY PROTEIN 6
          Length = 1081

 Score =  7.4 bits (24), Expect = 6.0
 Identities = 25/93 (26%), Positives = 37/93 (38%), Gaps = 17/93 (18%)

Query:  159 HFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI-IKNGGIQTESS 217
            +F S+N+   +S   L     E M  +      E C   L P   ++I   N  I  +S+
Sbjct:  642 NFTSKNEQEKISNDKL-----EVMVIKTVSTLCETCREELTPYLMHFISFLNTVIMPDSN 696

Query:  218 YPYTAETG--------TQCNFNSANIGPEEQAK 242
pattern 237                            ****
              +   T          QC  ++   GPEEQAK
Sbjct:  697 VSHFTRTKLVRSIGYVVQCQVSN---GPEEQAK 726


>sp|O49850|GCSP_FLAAN GLYCINE DEHYDROGENASE [DECARBOXYLATING], MITOCHONDRIAL PRECURSOR
            (GLYCINE DECARBOXYLASE) (GLYCINE CLEAVAGE SYSTEM
            P-PROTEIN)
          Length = 1034

 Score =  6.8 bits (22), Expect = 9.6
 Identities = 20/79 (25%), Positives = 38/79 (47%), Gaps = 13/79 (16%)

Query:  231 NSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPN 290
pattern 237       ****
            NSA   PEEQ K++ F      +++    I +T P +I  D++++  +  G+ +     +
Sbjct:  80  NSAT--PEEQTKMAEFVGFSNLDSL----IDATVPKSIRLDSMKYSKFDEGLTESQMIAH 133

Query:  291 SLDHGILIVGYSAKNTIFR 309
              D        ++KN IF+
Sbjct:  134 MQD-------LASKNKIFK 145


Searching..................................................done


Results from round 2


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value
Sequences used in model and found again:

Sequences not found previously or not previously below threshold:

sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR                  709  0.0
sp|P43295|A494_ARATH PROBABLE CYSTEINE PROTEINASE A494 PRECURSOR      273  4e-73
sp|P25804|CYSP_PEA CYSTEINE PROTEINASE 15A PRECURSOR (TURGOR-RES...   270  2e-72
sp|P43296|RD19_ARATH CYSTEINE PROTEINASE RD19A PRECURSOR              266  6e-71
sp|Q10716|CYS1_MAIZE CYSTEINE PROTEINASE 1 PRECURSOR                  252  6e-67
sp|P04989|CYS2_DICDI CYSTEINE PROTEINASE 2 PRECURSOR (PRESTALK C...   250  2e-66
sp|P54640|CYS5_DICDI CYSTEINE PROTEINASE 5 PRECURSOR                  238  1e-62
sp|P14658|CYSP_TRYBB CYSTEINE PROTEINASE PRECURSOR                    236  4e-62
sp|Q26534|CATL_SCHMA CATHEPSIN L PRECURSOR (SMCL1)                    233  3e-61
sp|P35591|CYS1_LEIPI CYSTEINE PROTEINASE 1 PRECURSOR (AMASTIGOTE...   233  3e-61
sp|P25775|LCPA_LEIME CYSTEINE PROTEINASE A PRECURSOR                  231  1e-60
sp|P13277|CYS1_HOMAM DIGESTIVE CYSTEINE PROTEINASE 1 PRECURSOR        221  1e-57
sp|P25779|CYSP_TRYCR CRUZIPAIN PRECURSOR (MAJOR CYSTEINE PROTEIN...   221  2e-57
sp|P41721|CATV_NPVBM VIRAL CATHEPSIN (V-CATH)                         216  5e-56
sp|P25782|CYS2_HOMAM DIGESTIVE CYSTEINE PROTEINASE 2 PRECURSOR        215  1e-55
sp|P41715|CATV_NPVCF VIRAL CATHEPSIN (V-CATH)                         214  2e-55
sp|P25784|CYS3_HOMAM DIGESTIVE CYSTEINE PROTEINASE 3 PRECURSOR        214  2e-55
sp|P07154|CATL_RAT CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN...   212  7e-55
sp|P06797|CATL_MOUSE CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTE...   212  1e-54
sp|P12412|CYSP_VIGMU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYS...   209  8e-54
sp|P25783|CATV_NPVAC VIRAL CATHEPSIN (V-CATH)                         209  8e-54
sp|P25975|CATL_BOVIN CATHEPSIN L PRECURSOR                            208  1e-53
sp|Q40143|CYS3_LYCES CYSTEINE PROTEINASE 3 PRECURSOR                  207  2e-53
sp|Q05094|CYS2_LEIPI CYSTEINE PROTEINASE 2 PRECURSOR (AMASTIGOTE...   207  3e-53
sp|P36400|LCPB_LEIME CYSTEINE PROTEINASE B PRECURSOR                  206  4e-53
sp|P07711|CATL_HUMAN CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTE...   206  4e-53
sp|Q28944|CATL_PIG CATHEPSIN L PRECURSOR                              206  5e-53
sp|P00785|ACTN_ACTCH ACTINIDAIN PRECURSOR (ACTINIDIN)                 204  3e-52
sp|P25803|CYSP_PHAVU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYS...   203  6e-52
sp|Q10991|CATL_SHEEP CATHEPSIN L                                      201  1e-51
sp|P43156|CYSP_HEMSP THIOL PROTEASE SEN102 PRECURSOR                  201  2e-51
sp|P54639|CYS4_DICDI CYSTEINE PROTEINASE 4 PRECURSOR                  200  3e-51
sp|O60911|CATM_HUMAN CATHEPSIN L2 PRECURSOR (CATHEPSIN V)             199  7e-51
sp|O10364|CATV_NPVOP VIRAL CATHEPSIN (V-CATH)                         196  5e-50
sp|P25777|ORYB_ORYSA ORYZAIN BETA CHAIN PRECURSOR                     196  5e-50
sp|P25776|ORYA_ORYSA ORYZAIN ALPHA CHAIN PRECURSOR                    194  2e-49
sp|P43297|RD21_ARATH CYSTEINE PROTEINASE RD21A PRECURSOR              193  4e-49
sp|Q10717|CYS2_MAIZE CYSTEINE PROTEINASE 2 PRECURSOR                  193  5e-49
sp|P14080|PAP2_CARPA CHYMOPAPAIN PRECURSOR (PAPAYA PROTEINASE II...   192  1e-48
sp|P00786|CATH_RAT CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPS...   192  1e-48
sp|P25251|CYS4_BRANA CYSTEINE PROTEINASE COT44 PRECURSOR              190  5e-48
sp|P09668|CATH_HUMAN CATHEPSIN H PRECURSOR                            188  2e-47
sp|P10056|PAP3_CARPA CARICAIN PRECURSOR (PAPAYA PROTEINASE OMEGA...   187  2e-47
sp|P25778|ORYC_ORYSA ORYZAIN GAMMA CHAIN PRECURSOR                    187  2e-47
sp|P15242|TES1_RAT TESTIN 1/2 PRECURSOR (CMB-22/CMB-23)               187  4e-47
sp|O46427|CATH_PIG CATHEPSIN H PRECURSOR                              186  5e-47
sp|P05167|ALEU_HORVU THIOL PROTEASE ALEURAIN PRECURSOR                185  9e-47
sp|P43235|CATK_HUMAN CATHEPSIN K PRECURSOR (CATHEPSIN O) (CATHEP...   185  1e-46
sp|P05994|PAP4_CARPA PAPAYA PROTEINASE IV PRECURSOR (PPIV) (PAPA...   184  3e-46
sp|P25250|CYS2_HORVU CYSTEINE PROTEINASE EP-B 2 PRECURSOR             183  3e-46
sp|P25249|CYS1_HORVU CYSTEINE PROTEINASE EP-B 1 PRECURSOR             183  5e-46
sp|P43236|CATK_RABIT CATHEPSIN K PRECURSOR (OC-2 PROTEIN)             183  6e-46
sp|P22895|P34_SOYBN P34 PROBABLE THIOL PROTEASE PRECURSOR             182  8e-46
sp|P49935|CATH_MOUSE CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHE...   180  5e-45
sp|P55097|CATK_MOUSE CATHEPSIN K PRECURSOR                            178  2e-44
sp|P56202|CATW_HUMAN CATHEPSIN W PRECURSOR (LYMPHOPAIN)               177  3e-44
sp|P56203|CATW_MOUSE CATHEPSIN W PRECURSOR (LYMPHOPAIN)               176  6e-44
sp|P43234|CATO_HUMAN CATHEPSIN O PRECURSOR                            173  4e-43
sp|P00784|PAPA_CARPA PAPAIN PRECURSOR (PAPAYA PROTEINASE I) (PPI)     173  7e-43
sp|P25774|CATS_HUMAN CATHEPSIN S PRECURSOR                            171  3e-42
sp||CATL_CHICK_1 [Segment 1 of 2] CATHEPSIN L                         167  2e-41
sp|P25326|CATS_BOVIN CATHEPSIN S                                      165  1e-40
sp|P80884|ANAN_ANACO ANANAIN                                          161  2e-39
sp|Q02765|CATS_RAT CATHEPSIN S PRECURSOR                              158  1e-38
sp|P20721|CYSL_LYCES LOW-TEMPERATURE-INDUCED CYSTEINE PROTEINASE...   158  2e-38
sp|P36184|ACP1_ENTHI CYSTEINE PROTEINASE ACP1 PRECURSOR               152  1e-36
sp|Q01957|CPP1_ENTHI CYSTEINE PROTEINASE 1 PRECURSOR                  150  4e-36
sp|O17473|CATL_BRUPA CATHEPSIN L-LIKE PRECURSOR                       150  6e-36
sp|P46102|CYSP_PLAVN CYSTEINE PROTEINASE PRECURSOR                    150  6e-36
sp|Q06964|CPP3_ENTHI CYSTEINE PROTEINASE 3 PRECURSOR (CYSTEINE P...   149  9e-36
sp|Q01958|CPP2_ENTHI CYSTEINE PROTEINASE 2 PRECURSOR                  149  9e-36
sp|P36185|ACP2_ENTHI CYSTEINE PROTEINASE ACP2 PRECURSOR               145  1e-34
sp|P25781|CYSP_THEAN CYSTEINE PROTEINASE PRECURSOR                    145  1e-34
sp|P22497|CYSP_THEPA CYSTEINE PROTEINASE PRECURSOR                    143  5e-34
sp|P25805|CYSP_PLAFA THROPHOZOITE CYSTEINE PROTEINASE PRECURSOR ...   141  3e-33
sp|P14518|BROM_ANACO BROMELAIN, STEM                                  139  6e-33
sp|P16311|MMAL_DERFA MAJOR MITE FECAL ALLERGEN DER F 1 PRECURSOR...   138  1e-32
sp|P42666|CYSP_PLAVI CYSTEINE PROTEINASE PRECURSOR                    129  1e-29
sp|P08176|MMAL_DERPT MAJOR MITE FECAL ALLERGEN DER P 1 PRECURSOR...   121  3e-27
sp|P80067|CATC_RAT DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPP...   111  3e-24
sp|P97821|CATC_MOUSE DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (D...   109  9e-24
sp|P25773|CATL_FELCA CATHEPSIN L (PROGESTERONE-DEPENDENT PROTEIN...   108  2e-23
sp|Q26563|CATC_SCHMA CATHEPSIN C PRECURSOR                            108  3e-23
sp|P53634|CATC_HUMAN DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (D...   107  3e-23
sp|P25780|EUM1_EURMA MITE GROUP I ALLERGEN EUR M 1 (EUR M I)          100  7e-21
sp|Q23894|CYS3_DICDI CYSTEINE PROTEINASE 3 (CYSTEINE PROTEINASE II)    95  2e-19
sp|P43509|CPR5_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 5 PREC...    91  4e-18
sp|P43508|CPR4_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 4 PREC...    90  5e-18
sp|P05993|PAP5_CARPA CYSTEINE PROTEINASE (CLONE PLBPC13)               90  5e-18
sp|P07688|CATB_BOVIN CATHEPSIN B PRECURSOR                             89  2e-17
sp|P00787|CATB_RAT CATHEPSIN B PRECURSOR (CATHEPSIN B1) (RSG-2)        87  4e-17
sp|P25807|CYS1_CAEEL GUT-SPECIFIC CYSTEINE PROTEINASE PRECURSOR        87  5e-17
sp|P07858|CATB_HUMAN CATHEPSIN B PRECURSOR (CATHEPSIN B1) (APP S...    86  9e-17
sp|P43157|CYSP_SCHJA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECUR...    85  2e-16
sp|P43233|CATB_CHICK CATHEPSIN B PRECURSOR (CATHEPSIN B1)              85  2e-16
sp|P43510|CPR6_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PREC...    85  2e-16
sp|P25792|CYSP_SCHMA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECUR...    85  3e-16
sp|P10605|CATB_MOUSE CATHEPSIN B PRECURSOR (CATHEPSIN B1)              85  3e-16
sp|P25802|CYS1_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PREC...    80  9e-15
sp|P25793|CYS2_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 2 PREC...    78  2e-14
sp|P19092|CYS1_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PREC...    78  4e-14
sp|P43507|CPR3_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 PREC...    73  7e-13
sp|P13823|SERA_PLAFG SERINE-REPEAT ANTIGEN PROTEIN PRECURSOR (P1...    70  6e-12
sp|P32956|CC3_CARCN CYSTEINE PROTEINASE III (CC-III)                   61  4e-09
sp|P32957|CC4_CARCN CYSTEINE PROTEINASE IV (CC-IV)                     60  9e-09
sp|Q06544|CYS3_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3            59  1e-08
sp|P32954|CC1_CARCN CYSTEINE PROTEINASE I (CC-I)                       58  3e-08
sp|P32955|CC2_CARCN CYSTEINE PROTEINASE II (CC-II)                     56  1e-07
sp||CATL_CHICK_2 [Segment 2 of 2] CATHEPSIN L                          52  2e-06
sp|P12399|CT2A_MOUSE CTLA-2-ALPHA PROTEIN PRECURSOR                    42  0.002
sp|P05689|CATX_BOVIN CATHEPSIN                                         40  0.006
sp|P12400|CT2B_MOUSE CTLA-2-BETA PROTEIN PRECURSOR                     39  0.019
sp|P23897|HSER_RAT HEAT-STABLE ENTEROTOXIN RECEPTOR PRECURSOR (G...    36  0.16
sp|P20736|BM86_BOOMI GLYCOPROTEIN ANTIGEN BM86 PRECURSOR (PROTEC...    35  0.22
sp|P46992|YJR1_YEAST HYPOTHETICAL 43.0 KD PROTEIN IN CPS1-FPP1 I...    32  1.9
sp|P28493|PR5_ARATH PATHOGENESIS-RELATED PROTEIN 5 PRECURSOR (PR-5)    32  1.9
sp|P54634|POLN_LORDV NON-STRUCTURAL POLYPROTEIN [CONTAINS: RNA-D...    31  3.2
sp|Q02521|SPP2_YEAST SPLICEOSOME MATURATION PROTEIN SPP2               31  4.2
sp|P41901|SPR3_YEAST SPORULATION-SPECIFIC SEPTIN                       31  4.2
sp|Q01532|BLH1_YEAST CYSTEINE PROTEINASE 1 (Y3) (BLEOMYCIN HYDRO...    30  5.5
sp|P24896|NU5M_CAEEL NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5            30  5.5
sp|P25648|SRB8_YEAST SUPPRESSOR OF RNA POLYMERASE B SRB8               30  7.2
sp|Q04723|PEPC_LACLC AMINOPEPTIDASE C                                  30  7.2
sp|Q13867|BLMH_HUMAN BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)         30  9.4
sp|P87362|BLMH_CHICK BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) (...    30  9.4
sp|P70645|BLMH_RAT BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)           30  9.4

>sp|P04988|CYS1_DICDI CYSTEINE PROTEINASE 1 PRECURSOR
          Length = 343

 Score =  709 bits (1811), Expect = 0.0
 Identities = 343/351 (97%), Positives = 343/351 (97%), Gaps = 8/351 (2%)

Query:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
            MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE
Sbjct:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60

Query:  61  ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPP 120
            ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 
Sbjct:  61  ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP- 119

Query:  121 EEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 180
               TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE
Sbjct:  120 ---TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 176

Query:  181 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQ 240
pattern 237                                                         ****
            CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG    
Sbjct:  177 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG---- 232

Query:  241 AKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVG 300
            AKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVG
Sbjct:  233 AKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVG 292

Query:  301 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII
Sbjct:  293 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 343


>sp|P43295|A494_ARATH PROBABLE CYSTEINE PROTEINASE A494 PRECURSOR
          Length = 313

 Score =  273 bits (691), Expect = 4e-73
 Identities = 149/324 (45%), Positives = 194/324 (58%), Gaps = 26/324 (8%)

Query:  32  FQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKA---DTKFGVNKFADLSSDE 87
            F+ KF K Y S EE+  RF +FK+NL       L A+ H+      + GV +F+DL+  E
Sbjct:  3   FKKKFGKVYGSIEEHYYRFSVFKANL-------LRAMRHQKMDPSARHGVTQFSDLTRSE 55

Query:  88  FKNYYLNNKEAI-FTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSC 146
            F+  +L  K       D   A  L  + +    PEE   FDWR RGAVTPVKNQG CGSC
Sbjct:  56  FRRKHLGVKGGFKLPKDANQAPILPTQNL----PEE---FDWRDRGAVTPVKNQGSCGSC 108

Query:  147 WSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI 206
            WSFSTTG +EG HF++  KLVSLSEQ LVDCDHEC + E E +CD GCNGGL  +A+ Y 
Sbjct:  109 WSFSTTGALEGAHFLATGKLVSLSEQQLVDCDHEC-DPEEEGSCDSGCNGGLMNSAFEYT 167

Query:  207 IKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPL 266
pattern 237                               ****
            +K GG+  E  YPYT   G  C  + + I     A +SNF+++  NE  +A  ++  GPL
Sbjct:  168 LKTGGLMREKDYPYTGTDGGSCKLDRSKI----VASVSNFSVVSINEDQIAANLIKNGPL 223

Query:  267 AIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAK--NTIFRKNMPYWIVKNSWGAD 324
            A+A +A   Q YIGGV         L+HG+L+VGY +   +    K  PYWI+KNSWG  
Sbjct:  224 AVAINAAYMQTYIGGVSCPYICSRRLNHGVLLVGYGSAGFSQARLKEKPYWIIKNSWGES 283

Query:  325 WGEQGYIYLRRGKNTCGVSNFVST 348
            WGE G+  + +G+N CGV + VST
Sbjct:  284 WGENGFYKICKGRNICGVDSLVST 307


>sp|P25804|CYSP_PEA CYSTEINE PROTEINASE 15A PRECURSOR (TURGOR-RESPONSIVE PROTEIN 15A)
          Length = 363

 Score =  270 bits (684), Expect = 2e-72
 Identities = 144/327 (44%), Positives = 201/327 (61%), Gaps = 20/327 (6%)

Query:  26  QSQFLEFQDKFNKKYS-HEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
            +  F  F+ KF+K Y+  EE+  RF +FKSNL K +    +  N     + G+ KF+DL+
Sbjct:  45  EHHFTSFKSKFSKSYATKEEHDYRFGVFKSNLIKAK----LHQNRDPTAEHGITKFSDLT 100

Query:  85  SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCG 144
            + EF+  +L  K+ +    LP           +  PE+   FDWR +GAVTPVK+QG CG
Sbjct:  101 ASEFRRQFLGLKKRL---RLPAHAQKAPILPTTNLPED---FDWREKGAVTPVKDQGSCG 154

Query:  145 SCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYN 204
            SCW+FSTTG +EG H+++  KLVSLSEQ LVDCDH C + E   +CD GCNGGL  NA+ 
Sbjct:  155 SCWAFSTTGALEGAHYLATGKLVSLSEQQLVDCDHVC-DPEQAGSCDSGCNGGLMNNAFE 213

Query:  205 YIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTG 264
pattern 237                                 ****
            Y++++GG+  E  Y YT   G+ C F+ + +     A +SNF+++  +E  +A  +V  G
Sbjct:  214 YLLESGGVVQEKDYAYTGRDGS-CKFDKSKV----VASVSNFSVVTLDEDQIAANLVKNG 268

Query:  265 PLAIAADAVEWQFYIGGV-FDIPCNPNSLDHGILIVGY--SAKNTIFRKNMPYWIVKNSW 321
            PLA+A +A   Q Y+ GV     C  + LDHG+L+VG+   A   I  K  PYWI+KNSW
Sbjct:  269 PLAVAINAAWMQTYMSGVSCPYVCAKSRLDHGVLLVGFGKGAYAPIRLKEKPYWIIKNSW 328

Query:  322 GADWGEQGYIYLRRGKNTCGVSNFVST 348
            G +WGEQGY  + RG+N CGV + VST
Sbjct:  329 GQNWGEQGYYKICRGRNVCGVDSMVST 355


>sp|P43296|RD19_ARATH CYSTEINE PROTEINASE RD19A PRECURSOR
          Length = 368

 Score =  266 bits (672), Expect = 6e-71
 Identities = 156/367 (42%), Positives = 206/367 (55%), Gaps = 42/367 (11%)

Query:  6   LFVLAVFTVFVSSR---------------GIPPE---EQSQFLEFQDKFNKKY-SHEEYL 46
            +FVL+ F V VSS                G  P+    +  F  F+ KF K Y S+EE+ 
Sbjct:  10  VFVLSFFIVSVSSSDVNDGDDLVIRQVVGGAEPQVLTSEDHFSLFKRKFGKVYASNEEHD 69

Query:  47  ERFEIFKSNLGKIEELNLIAINHKADTK--FGVNKFADLSSDEFKNYYLNNKEAI-FTDD 103
             RF +FK+NL +         + K D     GV +F+DL+  EF+  +L  +       D
Sbjct:  70  YRFSVFKANLRRARR------HQKLDPSATHGVTQFSDLTRSEFRKKHLGVRSGFKLPKD 123

Query:  104 LPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 163
               A  L  E +    PE+   FDWR  GAVTPVKNQG CGSCWSFS TG +EG +F++ 
Sbjct:  124 ANKAPILPTENL----PED---FDWRDHGAVTPVKNQGSCGSCWSFSATGALEGANFLAT 176

Query:  164 NKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAE 223
             KLVSLSEQ LVDCDHEC + E  ++CD GCNGGL  +A+ Y +K GG+  E  YPYT +
Sbjct:  177 GKLVSLSEQQLVDCDHEC-DPEEADSCDSGCNGGLMNSAFEYTLKTGGLMKEEDYPYTGK 235

Query:  224 TGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVF 283
pattern 237              ****
             G  C  + + I     A +SNF++I  +E  +A  +V  GPLA+A +A   Q YIGGV 
Sbjct:  236 DGKTCKLDKSKI----VASVSNFSVISIDEEQIAANLVKNGPLAVAINAGYMQTYIGGVS 291

Query:  284 DIPCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCG 341
                    L+HG+L+VGY A        K  PYWI+KNSWG  WGE G+  + +G+N CG
Sbjct:  292 CPYICTRRLNHGVLLVGYGAAGYAPARFKEKPYWIIKNSWGETWGENGFYKICKGRNICG 351

Query:  342 VSNFVST 348
            V + VST
Sbjct:  352 VDSMVST 358


>sp|Q10716|CYS1_MAIZE CYSTEINE PROTEINASE 1 PRECURSOR
          Length = 371

 Score =  252 bits (638), Expect = 6e-67
 Identities = 138/332 (41%), Positives = 190/332 (56%), Gaps = 23/332 (6%)

Query:  26  QSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
            +S FL F  +F K Y   +E+  R  +FK NL +     L+        + GV KF+DL+
Sbjct:  45  ESHFLSFVQRFGKSYKDADEHAYRLSVFKDNLRRARRHQLL----DPSAEHGVTKFSDLT 100

Query:  85  SDEFKNYYLN---NKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQG 141
              EF+  YL    ++ A+  +    A        + +P +    FDWR  GAV PVKNQG
Sbjct:  101 PAEFRRTYLGLRKSRRALLRELGESAHEAPVLPTDGLPDD----FDWRDHGAVGPVKNQG 156

Query:  142 QCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPN 201
             CGSCWSFS +G +EG H+++  KL  LSEQ  VDCDHEC   E  ++CD GCNGGL   
Sbjct:  157 SCGSCWSFSASGALEGAHYLATGKLEVLSEQQFVDCDHECDSSE-PDSCDSGCNGGLMTT 215

Query:  202 AYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIV 261
pattern 237                                    ****
            A++Y+ K GG+++E  YPYT   G +C F+ + I     A + NF+++  +E  ++  ++
Sbjct:  216 AFSYLQKAGGLESEKDYPYTGSDG-KCKFDKSKI----VASVQNFSVVSVDEAQISANLI 270

Query:  262 STGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKN 319
              GPLAI  +A   Q YIGGV         LDHG+L+VGY A     I  K+ PYWI+KN
Sbjct:  271 KHGPLAIGINAAYMQTYIGGVSCPYICGRHLDHGVLLVGYGASGFAPIRLKDKPYWIIKN 330

Query:  320 SWGADWGEQGYIYLRRG---KNTCGVSNFVST 348
            SWG +WGE GY  + RG   +N CGV + VST
Sbjct:  331 SWGENWGENGYYKICRGSNVRNKCGVDSMVST 362


>sp|P04989|CYS2_DICDI CYSTEINE PROTEINASE 2 PRECURSOR (PRESTALK CATHEPSIN)
          Length = 376

 Score =  250 bits (633), Expect = 2e-66
 Identities = 147/391 (37%), Positives = 213/391 (53%), Gaps = 63/391 (16%)

Query:  1   MKVILLFVLAVFTVFVSSRGIP-------PEEQSQFLEFQDKFNKKYSHEEYLERFEIFK 53
            M++++  +L +F  F  +   P        + ++ F E+  KFN++YS  E+  R+ IFK
Sbjct:  1   MRLLVFLILLIFVNFSFANVRPNGRRFSESQYRTAFTEWTLKFNRQYSSSEFSNRYSIFK 60

Query:  54  SNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK-EAIFTDDLPVADYLDD 112
            SN+  ++  N       + T  G+N FAD++++E++  YL  +  A   +     + L+ 
Sbjct:  61  SNMDYVDNWNS---KGDSQTVLGLNNFADITNEEYRKTYLGTRVNAHSYNGYDGREVLNV 117

Query:  113 EFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQ 172
            E + + P     + DWRT+ AVTP+K+QGQCGSCWSFSTTG+ EG H +   KLVSLSEQ
Sbjct:  118 EDLQTNPK----SIDWRTKNAVTPIKDQGQCGSCWSFSTTGSTEGAHALKTKKLVSLSEQ 173

Query:  173 NLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNS 232
            NLVDC        G E  + GC+GGL  NA++YIIKN GI TESSYPYTAETG+ C FN 
Sbjct:  174 NLVDC-------SGPEE-NFGCDGGLMNNAFDYIIKNKGIDTESSYPYTAETGSTCLFNK 225

Query:  233 ANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNP 289
pattern 237     ****
            ++IG    A I  +  I     +        GP+++A DA    +Q Y  G++  P C+P
Sbjct:  226 SDIG----ATIKGYVNITAGSEISLENGAQHGPVSVAIDASHNSFQLYTSGIYYEPKCSP 281

Query:  290 NSLDHGILIVGY--------------------------------SAKNTIFRKNMPYWIV 317
              LDHG+L+VGY                                 + +++  K   YWIV
Sbjct:  282 TELDHGVLVVGYGVQGKDDEGPVLNRKQTIVIHKNEDNKVESSDDSSDSVRPKANNYWIV 341

Query:  318 KNSWGADWGEQGYIYLRRG-KNTCGVSNFVS 347
            KNSWG  WG +GYI + +  KN CG+++  S
Sbjct:  342 KNSWGTSWGIKGYILMSKDRKNNCGIASVSS 372


>sp|P54640|CYS5_DICDI CYSTEINE PROTEINASE 5 PRECURSOR
          Length = 344

 Score =  238 bits (601), Expect = 1e-62
 Identities = 139/370 (37%), Positives = 201/370 (53%), Gaps = 45/370 (12%)

Query:  1   MKVI-LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKI 59
            MKV+  L VL V       +    + ++ F ++     K Y+ EE+  R+ IF +N+  +
Sbjct:  1   MKVLSFLCVLLVSVATAKQQFSELQYRNAFTDWMITHQKSYTSEEFGARYNIFTANMDYV 60

Query:  60  EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
            ++ N    +  ++T  G+N FAD++++E++N YL  K   F     +    +    NS  
Sbjct:  61  QQWN----SKGSETVLGLNNFADITNEEYRNTYLGTK---FDASSLIGTQEEKVHTNSSA 113

Query:  120 PEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 179
              +    DWR+ GAVTPVKNQGQCG CWSFSTTG+ EG HF S+ +LVSLSEQNL+DC  
Sbjct:  114 ASK----DWRSEGAVTPVKNQGQCGGCWSFSTTGSTEGAHFQSKGELVSLSEQNLIDCST 169

Query:  180 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEE 239
pattern 237                                                          ***
            E          + GC+GGL   A+ YII N GI TESSYPY AE G +C + S N G   
Sbjct:  170 E----------NSGCDGGLMTYAFEYIINNNGIDTESSYPYKAENG-KCEYKSENSG--- 215

Query:  240 QAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGI 296
pattern 240 *
             A +S++  +           V+  P+++A DA    +Q Y  G++  P C+  +LDHG+
Sbjct:  216 -ATLSSYKTVTAGSESSLESAVNVNPVSVAIDASHQSFQLYTSGIYYEPECSSENLDHGV 274

Query:  297 LIVGY--------------SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCG 341
            L VGY              S+ N     +  YWIVKNSWG  WG +GYI + R + N CG
Sbjct:  275 LAVGYGSGSGSSSGQSSGQSSGNLSASSSNEYWIVKNSWGTSWGIEGYILMSRNRDNNCG 334

Query:  342 VSNFVSTSII 351
            +++  S  ++
Sbjct:  335 IASSASFPVV 344


>sp|P14658|CYSP_TRYBB CYSTEINE PROTEINASE PRECURSOR
          Length = 450

 Score =  236 bits (597), Expect = 4e-62
 Identities = 137/354 (38%), Positives = 193/354 (53%), Gaps = 34/354 (9%)

Query:  3   VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEE 61
            V+L     + +V + S  +    + +F  F+ K+ K Y   +E   RF  F+ N+   E+
Sbjct:  15  VLLAMAACLASVALGSLHVEESLEMRFAAFKKKYGKVYKDAKEEAFRFRAFEENM---EQ 71

Query:  62  LNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPE 121
              + A  +   T FGV  F+D++ +EF+  Y N            A     + +N     
Sbjct:  72  AKIQAAANPYAT-FGVTPFSDMTREEFRARYRNGASYF-----AAAQKRLRKTVNVTTGR 125

Query:  122 EQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 181
               A DWR +GAVTPVK QGQCGSCW+FST GN+EGQ  ++ N LVSLSEQ LV CD   
Sbjct:  126 APAAVDWREKGAVTPVKVQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCD--- 182

Query:  182 MEYEGEEACDEGCNGGLQPNAYNYIIKN--GGIQTESSYPYTAETG--TQCNFNSANIGP 237
pattern 237                                                            *
                     D GCNGGL  NA+N+I+ +  G + TE+SYPY +  G   QC  N   IG 
Sbjct:  183 -------TIDSGCNGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIG- 234

Query:  238 EEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGIL 297
pattern 238 ***
               A I++   +P++E  +A Y+   GPLAIA DA  +  Y GG+    C    LDHG+L
Sbjct:  235 ---AAITDHVDLPQDEDAIAAYLAENGPLAIAVDAESFMDYNGGIL-TSCTSKQLDHGVL 290

Query:  298 IVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            +VGY+  +     N PYWI+KNSW   WGE GYI + +G N C ++  VS++++
Sbjct:  291 LVGYNDNS-----NPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVV 339


>sp|Q26534|CATL_SCHMA CATHEPSIN L PRECURSOR (SMCL1)
          Length = 319

 Score =  233 bits (589), Expect = 3e-61
 Identities = 128/334 (38%), Positives = 190/334 (56%), Gaps = 30/334 (8%)

Query:  21  IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
            +P     ++++F+ K+ K+Y   E   RF IFKSN+ K +   L  +  +    +GV  +
Sbjct:  12  LPGNVDEKYVQFKLKYRKQYHETEDEIRFNIFKSNILKAQ---LYQVFVRGSAIYGVTPY 68

Query:  81  ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQ 140
            +DL++DEF   +L     + +        L  E +N+IP      FDWR +GAVT VKNQ
Sbjct:  69  SDLTTDEFARTHLTASWVVPSSRSNTPTSLGKE-VNNIPKN----FDWREKGAVTEVKNQ 123

Query:  141 GQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQP 200
            G CGSCW+FSTTGNVE Q F    KL+SLSEQ LVDCD            D+GCNGGL  
Sbjct:  124 GMCGSCWAFSTTGNVESQWFRKTGKLLSLSEQQLVDCD----------GLDDGCNGGLPS 173

Query:  201 NAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYI 260
pattern 237                                     ****
            NAY  IIK GG+  E +YPY A+   +C+  +  +       I++   + ++ET +A ++
Sbjct:  174 NAYESIIKMGGLMLEDNYPYDAK-NEKCHLKTDGVA----VYINSSVNLTQDETELAAWL 228

Query:  261 VSTGPLAIAADAVEWQFYIGGV---FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIV 317
                 +++  +A+  QFY  G+   + I C+   LDH +L+VGY     +  KN P+WIV
Sbjct:  229 YHNSTISVGMNALLLQFYQHGISHPWWIFCSKYLLDHAVLLVGYG----VSEKNEPFWIV 284

Query:  318 KNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            KNSWG +WGE GY  + RG  +CG++   ++++I
Sbjct:  285 KNSWGVEWGENGYFRMYRGDGSCGINTVATSAMI 318


>sp|P35591|CYS1_LEIPI CYSTEINE PROTEINASE 1 PRECURSOR (AMASTIGOTE CYSTEINE PROTEINASE A-1)
          Length = 354

 Score =  233 bits (589), Expect = 3e-61
 Identities = 144/355 (40%), Positives = 192/355 (53%), Gaps = 40/355 (11%)

Query:  5   LLFVLAVFTVFVSSRGI-------PPEEQ----SQFLEFQDKFNKKYSHE-EYLERFEIF 52
            LLF + V  +FV   G        PP +     + +  F+ +  K +  + E   RF  F
Sbjct:  7   LLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAF 66

Query:  53  KSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDD 112
            K N+     LN    +   D      KFADL+  EF   YLN           + D+ +D
Sbjct:  67  KQNMQTAYFLNTQNPHAHYDVS---GKFADLTPQEFAKLYLNPDYYA----RHLKDHKED 119

Query:  113 EFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQ 172
              ++   P    + DWR +GAVTPVKNQG CGSCW+FS  GN+EGQ   S + LVSLSEQ
Sbjct:  120 VHVDDSAPSGVMSVDWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSLVSLSEQ 179

Query:  173 NLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETGTQCNF 230
             LV CD+           DEGCNGGL   A N+I++  NG + TE+SYPYT+  GT+   
Sbjct:  180 MLVSCDN----------IDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGGGTRPPC 229

Query:  231 NSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPN 290
pattern 237       ****
            +      E  AKI+ F  +P +E  +A ++   GP+A+A DA  WQ Y GGV  + C   
Sbjct:  230 HDEG---EVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVSL-CLAW 285

Query:  291 SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNF 345
            SL+HG+LIVG++ KN       PYWIVKNSWG+ WGE+GYI L  G N C + N+
Sbjct:  286 SLNHGVLIVGFN-KNA----KPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNY 335


>sp|P25775|LCPA_LEIME CYSTEINE PROTEINASE A PRECURSOR
          Length = 354

 Score =  231 bits (584), Expect = 1e-60
 Identities = 143/355 (40%), Positives = 192/355 (53%), Gaps = 40/355 (11%)

Query:  5   LLFVLAVFTVFVSSRGI-------PPEEQ----SQFLEFQDKFNKKYSHE-EYLERFEIF 52
            LLF + V  +FV   G        PP +     + +  F+ +  K +  + E   RF  F
Sbjct:  7   LLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAF 66

Query:  53  KSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDD 112
            K N+     LN    +   D      KFADL+  EF   YLN           + ++ +D
Sbjct:  67  KQNMQTAYFLNTQNPHAHYDVS---GKFADLTPQEFAKLYLNPDYYA----RHLKNHKED 119

Query:  113 EFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQ 172
              ++   P    + DWR +GAVTPVKNQG CGSCW+FS  GN+EGQ   S + LVSLSEQ
Sbjct:  120 VHVDDSAPSGVMSVDWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSLVSLSEQ 179

Query:  173 NLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETGTQCNF 230
             LV CD+           DEGCNGGL   A N+I++  NG + TE+SYPYT+  GT+   
Sbjct:  180 MLVSCDN----------IDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGGGTRPPC 229

Query:  231 NSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPN 290
pattern 237       ****
            +      E  AKI+ F  +P +E  +A ++   GP+A+A DA  WQ Y GGV  + C   
Sbjct:  230 HDEG---EVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVSL-CLAW 285

Query:  291 SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNF 345
            SL+HG+LIVG++ KN       PYWIVKNSWG+ WGE+GYI L  G N C + N+
Sbjct:  286 SLNHGVLIVGFN-KNA----KPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNY 335


>sp|P13277|CYS1_HOMAM DIGESTIVE CYSTEINE PROTEINASE 1 PRECURSOR
          Length = 322

 Score =  221 bits (558), Expect = 1e-57
 Identities = 132/349 (37%), Positives = 184/349 (51%), Gaps = 41/349 (11%)

Query:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKI 59
            MKV+ LF+  +     +           + EF+ KF +KY   EE   R  +F  NL  I
Sbjct:  1   MKVVALFLFGLALAAANP---------SWEEFKGKFGRKYVDLEEERYRLNVFLDNLQYI 51

Query:  60  EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
            EE N      +      +N+F+D+++++F       K+       P A      F ++  
Sbjct:  52  EEFNKKYERGEVTYNLAINQFSDMTNEKFNAVMKGYKKG----PRPAA-----VFTSTDA 102

Query:  120 PEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 179
              E T  DWRT+GAVTPVK+QGQCGSCW+FSTTG +EGQHF+   +LVSLSEQ LVDC  
Sbjct:  103 APESTEVDWRTKGAVTPVKDQGQCGSCWAFSTTGGIEGQHFLKTGRLVSLSEQQLVDC-- 160

Query:  180 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEE 239
pattern 237                                                          ***
                  G    ++GCNGG    A  Y+  NGG+ TESSYPY A   T C FNS  IG   
Sbjct:  161 -----AGGSYYNQGCNGGWVERAIMYVRDNGGVDTESSYPYEARDNT-CRFNSNTIG--- 211

Query:  240 QAKISNFTMIPK-NETVMAGYIVSTGPLAIAADAVEWQF---YIGGVFDIPCNPNSLDHG 295
pattern 240 *
             A  + +  I + +E+ +       GP+++A DA    F   Y G  ++  C+ + LDH 
Sbjct:  212 -ATCTGYVGIAQGSESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHA 270

Query:  296 ILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVS 343
            +L VGY ++         +W+VKNSW   WGE GYI + R + N CG++
Sbjct:  271 VLAVGYGSEG-----GQDFWLVKNSWATSWGESGYIKMARNRNNNCGIA 314


>sp|P25779|CYSP_TRYCR CRUZIPAIN PRECURSOR (MAJOR CYSTEINE PROTEINASE) (CRUZAINE)
          Length = 467

 Score =  221 bits (557), Expect = 2e-57
 Identities = 134/358 (37%), Positives = 189/358 (52%), Gaps = 38/358 (10%)

Query:  3   VILLFVLAVFTVFV--SSRGIPPEEQ--SQFLEFQDKFNKKY-SHEEYLERFEIFKSNLG 57
            ++L  VL V    V  ++  +  EE   SQF EF+ K  + Y S  E   R  +F+ NL 
Sbjct:  8   LLLAAVLVVMACLVPAATASLHAEETLTSQFAEFKQKHGRVYESAAEEAFRLSVFRENLF 67

Query:  58  KIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINS 117
             +  L+  A  H     FGV  F+DL+ +EF++ Y N               +  E + +
Sbjct:  68  -LARLHAAANPHAT---FGVTPFSDLTREEFRSRYHNGAAHFAAAQERARVPVKVEVVGA 123

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDC 177
                   A DWR RGAVT VK+QGQCGSCW+FS  GNVE Q F++ + L +LSEQ LV C
Sbjct:  124 -----PAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSC 178

Query:  178 DHECMEYEGEEACDEGCNGGLQPNAYNYIIK--NGGIQTESSYPYTAETGTQ--CNFNSA 233
            D            D GC+GGL  NA+ +I++  NG + TE SYPY +  G    C  +  
Sbjct:  179 D----------KTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGH 228

Query:  234 NIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLD 293
pattern 237    ****
             +G    A I+    +P++E  +A ++   GP+A+A DA  W  Y GGV    C    LD
Sbjct:  229 TVG----ATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVM-TSCVSEQLD 283

Query:  294 HGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            HG+L+VGY+    +     PYWI+KNSW   WGE+GYI + +G N C V    S++++
Sbjct:  284 HGVLLVGYNDSAAV-----PYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVV 336


>sp|P41721|CATV_NPVBM VIRAL CATHEPSIN (V-CATH)
          Length = 323

 Score =  216 bits (545), Expect = 5e-56
 Identities = 131/349 (37%), Positives = 181/349 (51%), Gaps = 32/349 (9%)

Query:  5   LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELN 63
            +LF L V+ V  S+   P +  + F EF  +FNK YS E E L RF+IF+ NL +I    
Sbjct:  4   ILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI---- 59

Query:  64  LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQ 123
             I  N     K+ +NKF+DLS DE    Y        T +      LD       P +  
Sbjct:  60  -INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQP-----PGKGP 113

Query:  124 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 183
              FDWR    VT VKNQG CG+CW+F+T G++E Q  I  N+L++LSEQ ++DCD     
Sbjct:  114 LEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDF---- 169

Query:  184 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKI 243
pattern 237                                                      ****
                   D GCNGGL   A+  IIK GG+Q ES YPY A+    C  NS     + +   
Sbjct:  170 ------VDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEAD-NNNCRMNSNKFLVQVK--- 219

Query:  244 SNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSA 303
              +  I   E  +   +   GP+ +A DA +   Y  G+    C  + L+H +L+VGY  
Sbjct:  220 DCYRYIIVYEEKLKDLLPLVGPIPMAIDAADIVNYKQGIIKY-CFDSGLNHAVLLVGYGV 278

Query:  304 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN-FVSTSII 351
            +N     N+PYW  KN+WG DWGE G+  +++  N CG+ N   ST++I
Sbjct:  279 EN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 322


>sp|P25782|CYS2_HOMAM DIGESTIVE CYSTEINE PROTEINASE 2 PRECURSOR
          Length = 323

 Score =  215 bits (541), Expect = 1e-55
 Identities = 132/357 (36%), Positives = 189/357 (51%), Gaps = 40/357 (11%)

Query:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKI 59
            MKV +LF+  V     S           +  F+ K+ ++Y   EE   R  IF+ N   I
Sbjct:  1   MKVAVLFLCGVALAAASP---------SWEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYI 51

Query:  60  EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIP 119
            EE N    N +      +NKF D++ +EF      N   I     PV+ +   +      
Sbjct:  52  EEFNKKYENGEVTFNLAMNKFGDMTLEEFNAVMKGN---IPRRSAPVSVFYPKKETGP-- 106

Query:  120 PEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 179
              + T  DWRT+GAVTPVK+QGQCGSCW+FSTTG++EGQHF+    L+SL+EQ LVDC  
Sbjct:  107 --QATEVDWRTKGAVTPVKDQGQCGSCWAFSTTGSLEGQHFLKTGSLISLAEQQLVDC-- 162

Query:  180 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEE 239
pattern 237                                                          ***
                        +GCNGG   +A++YI  N GI TE++YPY A  G+ C F+S ++    
Sbjct:  163 ------SRPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPYEARDGS-CRFDSNSVA--- 212

Query:  240 QAKISNFTMIPK-NETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHG 295
pattern 240 *
             A  S  T I   +ET +   +   GP+++  DA    +QFY  GV+  P C+P+ LDH 
Sbjct:  213 -ATCSGHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHA 271

Query:  296 ILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 351
            +L VGY ++         +W+VKNSW   WG+ GYI + R + N CG++   S  ++
Sbjct:  272 VLAVGYGSEG-----GQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323


>sp|P41715|CATV_NPVCF VIRAL CATHEPSIN (V-CATH)
          Length = 324

 Score =  214 bits (540), Expect = 2e-55
 Identities = 130/351 (37%), Positives = 188/351 (53%), Gaps = 33/351 (9%)

Query:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
            M  I+L++L    V  ++  +  +  + F +F  KFNK YS E E L RF+IF+ NL +I
Sbjct:  1   MNKIVLYLLVYGAVQCAAYDVL-KAPNYFEDFLHKFNKSYSSESEKLRRFQIFRHNLEEI 59

Query:  60  EELNLIAINHKADT-KFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSI 118
                 I  NH   T ++ +NKFADLS DE  + Y      + T +      LD       
Sbjct:  60  -----INKNHNDSTAQYEINKFADLSKDETISKYTGLSLPLQTQNFCEVVVLDRP----- 109

Query:  119 PPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCD 178
            P +    FDWR    VT VKNQG CG+CW+F+T G++E Q  I  N+ ++LSEQ L+DCD
Sbjct:  110 PDKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNQFINLSEQQLIDCD 169

Query:  179 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPE 238
pattern 237                                                           **
                        D GC+GGL   A+  ++  GGIQ ES YPY A  G  C  N+A    +
Sbjct:  170 F----------VDAGCDGGLLHTAFEAVMNMGGIQAESDYPYEANNG-DCRANAAKFVVK 218

Query:  239 EQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILI 298
pattern 239 **
             +      T+    E  +   + S GP+ +A DA +   Y  G+    C  + L+H +L+
Sbjct:  219 VKKCYRYITVF---EEKLKDLLRSVGPIPVAIDASDIVNYKRGIMKY-CANHGLNHAVLL 274

Query:  299 VGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 349
            VGY+ +N      +P+WI+KN+WGADWGEQGY  +++  N CG+ N + +S
Sbjct:  275 VGYAVEN-----GVPFWILKNTWGADWGEQGYFRVQQNINACGIQNELPSS 320


>sp|P25784|CYS3_HOMAM DIGESTIVE CYSTEINE PROTEINASE 3 PRECURSOR
          Length = 321

 Score =  214 bits (539), Expect = 2e-55
 Identities = 125/326 (38%), Positives = 184/326 (56%), Gaps = 47/326 (14%)

Query:  32  FQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEF-- 88
            F+ ++ +KY   +E L R  +F+ N   IE+ N    N +   K  +N+F D++++EF  
Sbjct:  23  FKTQYGRKYGDAKEELYRQRVFQQNEQLIEDFNKKFENGEVTFKVAMNQFGDMTNEEFNA 82

Query:  89  --KNYYLNNK---EAIFTDDL-PVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQ 142
              K Y   ++   +A+FT +  P+A                   DWRT+  VTPVK+Q Q
Sbjct:  83  VMKGYKKGSRGEPKAVFTAEAGPMA----------------ADVDWRTKALVTPVKDQEQ 126

Query:  143 CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNA 202
            CGSCW+FS TG +EGQHF+  ++LVSLSEQ LVDC          +  ++GC GG   +A
Sbjct:  127 CGSCWAFSATGALEGQHFLKNDELVSLSEQQLVDC--------STDYGNDGCGGGWMTSA 178

Query:  203 YNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVS 262
pattern 237                                   ****
            ++YI  NGGI TESSYPY AE    C F++ +IG    A  +    +   E  +   +  
Sbjct:  179 FDYIKDNGGIDTESSYPYEAE-DRSCRFDANSIG----AICTGSVEVQHTEEALQEAVSG 233

Query:  263 TGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKN 319
             GP+++A DA    +QFY  GV ++  C+P  LDHG+L VGY  ++T       YW+VKN
Sbjct:  234 VGPISVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTEST-----KDYWLVKN 288

Query:  320 SWGADWGEQGYIYLRRGK-NTCGVSN 344
            SWG+ WG+ GYI + R + N CG+++
Sbjct:  289 SWGSSWGDAGYIKMSRNRDNNCGIAS 314


>sp|P07154|CATL_RAT CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP) (CYCLIC
            PROTEIN-2) (CP-2)
          Length = 334

 Score =  212 bits (535), Expect = 7e-55
 Identities = 127/359 (35%), Positives = 195/359 (53%), Gaps = 39/359 (10%)

Query:  3   VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEEL 62
            ++LL VL + T   + +       +Q+ +++    + Y   E   R  +++ N+  I+  
Sbjct:  4   LLLLAVLCLGTALATPK-FDQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLH 62

Query:  63  NLIAINHKADTKFGVNKFADLSSDEFKN------YYLNNKEAIFTDDLPVADYLDDEFIN 116
            N    N K      +N F D++++EF+       +  + K  +F + L +          
Sbjct:  63  NGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHKKGRLFQEPLML---------- 112

Query:  117 SIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 176
             IP       DWR +G VTPVKNQGQCGSCW+FS +G +EGQ F+   KL+SLSEQNLVD
Sbjct:  113 QIPK----TVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVD 168

Query:  177 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 236
            C H+    +G    ++GCNGGL   A+ YI +NGG+ +E SYPY A+ G+ C + +    
Sbjct:  169 CSHD----QG----NQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGS-CKYRA---- 215

Query:  237 PEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLD 293
pattern 237 ****
                A  + F  IP+ E  +   + + GP+++A DA     QFY  G++  P C+   LD
Sbjct:  216 EYAVANDTGFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLD 275

Query:  294 HGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVSTSII 351
            HG+L+VGY  + T   K+  YW+VKNSWG +WG  GYI + + +N  CG++   S  I+
Sbjct:  276 HGVLVVGYGYEGTDSNKD-KYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333


>sp|P06797|CATL_MOUSE CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP)
          Length = 334

 Score =  212 bits (533), Expect = 1e-54
 Identities = 126/359 (35%), Positives = 198/359 (55%), Gaps = 39/359 (10%)

Query:  3   VILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEEL 62
            ++LL VL + T   + +       +++ +++    + Y   E   R  I++ N+  I+  
Sbjct:  4   LLLLAVLCLGTALATPK-FDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLH 62

Query:  63  NLIAINHKADTKFGVNKFADLSSDEFKN------YYLNNKEAIFTDDLPVADYLDDEFIN 116
            N    N +      +N F D++++EF+       +  + K  +F + L +          
Sbjct:  63  NGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLML---------- 112

Query:  117 SIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 176
             IP     + DWR +G VTPVKNQGQCGSCW+FS +G +EGQ F+   KL+SLSEQNLVD
Sbjct:  113 KIPK----SVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVD 168

Query:  177 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 236
            C H     +G    ++GCNGGL   A+ YI +NGG+ +E SYPY A+ G+ C + +    
Sbjct:  169 CSHA----QG----NQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGS-CKYRA---- 215

Query:  237 PEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLD 293
pattern 237 ****
                A  + F  IP+ E  +   + + GP+++A DA     QFY  G++  P C+  +LD
Sbjct:  216 EFAVANDTGFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLD 275

Query:  294 HGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVSTSII 351
            HG+L+VGY  + T   KN  YW+VKNSWG++WG +GYI + + + N CG++   S  ++
Sbjct:  276 HGVLLVGYGYEGTDSNKN-KYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333


>sp|P12412|CYSP_VIGMU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYSTEINE PROTEINASE)
            (SULFHYDRYL-ENDOPEPTIDASE) (SH-EP)
          Length = 362

 Score =  209 bits (526), Expect = 8e-54
 Identities = 127/313 (40%), Positives = 179/313 (56%), Gaps = 35/313 (11%)

Query:  47  ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK---EAIFTDD 103
            +RF +FK+N+  +   N +   +K      +NKFAD+++ EF++ Y  +K     +F   
Sbjct:  58  KRFNVFKANVMHVHNTNKMDKPYKLK----LNKFADMTNHEFRSTYAGSKVNHHKMFRGS 113

Query:  104 LPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 163
               +     E + S+P     + DWR +GAVT VK+QGQCGSCW+FST   VEG + I  
Sbjct:  114 QHGSGTFMYEKVGSVP----ASVDWRKKGAVTDVKDQGQCGSCWAFSTIVAVEGINQIKT 169

Query:  164 NKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAE 223
            NKLVSLSEQ LVDCD E          ++GCNGGL  +A+ +I + GGI TES+YPYTA+
Sbjct:  170 NKLVSLSEQELVDCDKE---------ENQGCNGGLMESAFEFIKQKGGITTESNYPYTAQ 220

Query:  224 TGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGG 281
pattern 237              ****
             GT C+ +  N   +    I     +P N+       V+  P+++A DA   ++QFY  G
Sbjct:  221 EGT-CDESKVN---DLAVSIDGHENVPVNDENALLKAVANQPVSVAIDAGGSDFQFYSEG 276

Query:  282 VFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----K 337
            VF   CN   L+HG+ IVGY    T+   N  YWIV+NSWG +WGEQGYI ++R     +
Sbjct:  277 VFTGDCN-TDLNHGVAIVGYG--TTVDGTN--YWIVRNSWGPEWGEQGYIRMQRNISKKE 331

Query:  338 NTCGVSNFVSTSI 350
              CG++   S  I
Sbjct:  332 GLCGIAMMASYPI 344


>sp|P25783|CATV_NPVAC VIRAL CATHEPSIN (V-CATH)
          Length = 323

 Score =  209 bits (526), Expect = 8e-54
 Identities = 129/349 (36%), Positives = 179/349 (50%), Gaps = 32/349 (9%)

Query:  5   LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELN 63
            +LF L V+ V  S+     +  + F EF  +FNK Y  E E L RF+IF+ NL +I    
Sbjct:  4   ILFYLFVYGVVNSAAYDLLKAPNYFEEFVHRFNKDYGSEVEKLRRFKIFQHNLNEI---- 59

Query:  64  LIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQ 123
             I  N     K+ +NKF+DLS DE    Y      I T +      LD       P +  
Sbjct:  60  -INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPIQTQNFCKVIVLDQP-----PGKGP 113

Query:  124 TAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 183
              FDWR    VT VKNQG CG+CW+F+T  ++E Q  I  N+L++LSEQ ++DCD     
Sbjct:  114 LEFDWRRLNKVTSVKNQGMCGACWAFATLASLESQFAIKHNQLINLSEQQMIDCDF---- 169

Query:  184 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKI 243
pattern 237                                                      ****
                   D GCNGGL   A+  IIK GG+Q ES YPY A+    C  NS     + +   
Sbjct:  170 ------VDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEAD-NNNCRMNSNKFLVQVK--- 219

Query:  244 SNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSA 303
              +  I   E  +   +   GP+ +A DA +   Y  G+    C  + L+H +L+VGY  
Sbjct:  220 DCYRYITVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIKY-CFNSGLNHAVLLVGYGV 278

Query:  304 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN-FVSTSII 351
            +N     N+PYW  KN+WG DWGE G+  +++  N CG+ N   ST++I
Sbjct:  279 EN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 322


>sp|P25975|CATL_BOVIN CATHEPSIN L PRECURSOR
          Length = 334

 Score =  208 bits (525), Expect = 1e-53
 Identities = 126/351 (35%), Positives = 184/351 (51%), Gaps = 35/351 (9%)

Query:  7   FVLAVFTVFVSSRG--IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNL 64
            F L V  + V+S    + P   + + +++    + Y   E   R  +++ N   I+  N 
Sbjct:  5   FFLTVLCLGVASAAPKLDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQ 64

Query:  65  IAINHKADTKFGVNKFADLSSDEFK---NYYLNNKEAIFTDDLPVADYLDDEFINSIPPE 121
                 K   +  +N F D++++EF+   N + N K               +  +  +P  
Sbjct:  65  EYSEGKHAFRMAMNAFGDMTNEEFRQVMNGFQNQKHK-------KGKLFHEPLLVDVPK- 116

Query:  122 EQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 181
               + DW  +G VTPVKNQGQCGSCW+FS TG +EGQ F    KLVSLSEQNLVDC    
Sbjct:  117 ---SVDWTKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRA- 172

Query:  182 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPE-EQ 240
pattern 237                                                        ** **
               +G    ++GCNGGL  NA+ YI  NGG+ +E SYPY A     CN+      PE   
Sbjct:  173 ---QG----NQGCNGGLMDNAFQYIKDNGGLDSEESYPYLATDTNSCNYK-----PECSA 220

Query:  241 AKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGIL 297
            A  + F  IP+ E  +   + + GP+++A DA    +QFY  G+ +D  C+   LDHG+L
Sbjct:  221 ANDTGFVDIPQREKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVL 280

Query:  298 IVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVS 347
            +VGY  + T    N  +WIVKNSWG +WG  GY+ + + +N  CG++   S
Sbjct:  281 VVGYGFEGTDSNNN-KFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAAS 330


>sp|Q40143|CYS3_LYCES CYSTEINE PROTEINASE 3 PRECURSOR
          Length = 356

 Score =  207 bits (522), Expect = 2e-53
 Identities = 129/331 (38%), Positives = 181/331 (53%), Gaps = 40/331 (12%)

Query:  29  FLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
            F  F  +  K+Y S EE  +RFEIF  NL  I   N   +++K     G+N+F DL+ DE
Sbjct:  57  FARFAIRHRKRYDSVEEIKQRFEIFLDNLKMIRSHNRKGLSYK----LGINEFTDLTWDE 112

Query:  88  FKNYYLN---NKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCG 144
            F+ + L    N  A    +L +         N + PE +   DWR  G V+PVK QG+CG
Sbjct:  113 FRKHKLGASQNCSATTKGNLKLT--------NVVLPETK---DWRKDGIVSPVKAQGKCG 161

Query:  145 SCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYN 204
            SCW+FSTTG +E  +  +  K +SLSEQ LVDC      +        GCNGGL   A+ 
Sbjct:  162 SCWTFSTTGALEAAYAQAFGKGISLSEQQLVDCAGAFNNF--------GCNGGLPSQAFE 213

Query:  205 YIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTG 264
pattern 237                                 ****
            YI  NGG+ TE +YPYT + G  C F+ ANIG +  + + N T+  + E   A  +V   
Sbjct:  214 YIKFNGGLDTEEAYPYTGKNGI-CKFSQANIGVKVISSV-NITLGAEYELKYAVALVR-- 269

Query:  265 PLAIAADAVE-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNS 320
            P+++A + V+ ++ Y  GV+   +    P  ++H +L VGY  +N       PYW++KNS
Sbjct:  270 PVSVAFEVVKGFKQYKSGVYASTECGDTPMDVNHAVLAVGYGVEN-----GTPYWLIKNS 324

Query:  321 WGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            WGADWGE GY  +  GKN CGV+   S  I+
Sbjct:  325 WGADWGEDGYFKMEMGKNMCGVATCASYPIV 355


>sp|Q05094|CYS2_LEIPI CYSTEINE PROTEINASE 2 PRECURSOR (AMASTIGOTE CYSTEINE PROTEINASE A-2)
          Length = 444

 Score =  207 bits (521), Expect = 3e-53
 Identities = 122/327 (37%), Positives = 177/327 (53%), Gaps = 39/327 (11%)

Query:  29  FLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKA---DTKFGVNKFADLS 84
            F EF+  + + Y    E  +R   F+ NL  + E       H+A     +FG+ KF DLS
Sbjct:  38  FEEFKRTYGRAYETLAEEQQRLANFERNLELMRE-------HQARNPHAQFGITKFFDLS 90

Query:  85  SDEFKNYYLNNKEAIFTDDLPVADYLDDEF--INSIPPEEQTAFDWRTRGAVTPVKNQGQ 142
              EF   YLN            A +       ++++P     A DWR +GAVTPVK+QG 
Sbjct:  91  EAEFAARYLNGAAYFAAAKRHAAQHYRKARADLSAVPD----AVDWREKGAVTPVKDQGA 146

Query:  143 CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNA 202
            CGSCW+FS  GN+EGQ +++ ++LVSLSEQ LV CD            ++GC+GGL   A
Sbjct:  147 CGSCWAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDD----------MNDGCDGGLMLQA 196

Query:  203 YNYIIK--NGGIQTESSYPYTAETG--TQCNFNSANIGPEEQAKISNFTMIPKNETVMAG 258
pattern 237                                       ****
            ++++++  NG + TE SYPY +  G   +C+ +S  +     A+I    +I  +E  MA 
Sbjct:  197 FDWLLQNTNGHLHTEDSYPYVSGNGYVPECSNSSEEL--VVGAQIDGHVLIGSSEKAMAA 254

Query:  259 YIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVK 318
            ++   GP+AIA DA  +  Y  GV    C    L+HG+L+VGY     +     PYW++K
Sbjct:  255 WLAKNGPIAIALDASSFMSYKSGVL-TACIGKQLNHGVLLVGYDMTGEV-----PYWVIK 308

Query:  319 NSWGADWGEQGYIYLRRGKNTCGVSNF 345
            NSWG DWGEQGY+ +  G N C +S +
Sbjct:  309 NSWGGDWGEQGYVRVVMGVNACLLSEY 335


>sp|P36400|LCPB_LEIME CYSTEINE PROTEINASE B PRECURSOR
          Length = 443

 Score =  206 bits (520), Expect = 4e-53
 Identities = 122/327 (37%), Positives = 177/327 (53%), Gaps = 40/327 (12%)

Query:  29  FLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKA---DTKFGVNKFADLS 84
            F EF+  + + Y    E  +R   F+ NL  + E       H+A     +FG+ KF DLS
Sbjct:  38  FEEFKRTYGRAYETLAEEQQRLANFERNLELMRE-------HQARNPHAQFGITKFFDLS 90

Query:  85  SDEFKNYYLNNKEAIFTDDLPVADYLDDEF--INSIPPEEQTAFDWRTRGAVTPVKNQGQ 142
              EF   YLN            A +       ++++P     A DWR +GAVTPVK+QG 
Sbjct:  91  EAEFAARYLNGAAYFAAAKRHAAQHYRKARADLSAVPD----AVDWREKGAVTPVKDQGA 146

Query:  143 CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNA 202
            CGSCW+FS  GN+EGQ +++ ++LVSLSEQ LV CD            ++GC+GGL   A
Sbjct:  147 CGSCWAFSAVGNIEGQWYLAGHELVSLSEQQLVSCDD----------MNDGCDGGLMLQA 196

Query:  203 YNYIIK--NGGIQTESSYPYTAETG--TQCNFNSANIGPEEQAKISNFTMIPKNETVMAG 258
pattern 237                                       ****
            ++++++  NG + TE SYPY +  G   +C+ +S  +     A+I    +I  +E  MA 
Sbjct:  197 FDWLLQNTNGHLHTEDSYPYVSGNGYVPECSNSSELV---VGAQIDGHVLIGSSEKAMAA 253

Query:  259 YIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVK 318
            ++   GP+AIA DA  +  Y  GV    C    L+HG+L+VGY     +     PYW++K
Sbjct:  254 WLAKNGPIAIALDASSFMSYKSGVL-TACIGKQLNHGVLLVGYDMTGEV-----PYWVIK 307

Query:  319 NSWGADWGEQGYIYLRRGKNTCGVSNF 345
            NSWG DWGEQGY+ +  G N C +S +
Sbjct:  308 NSWGGDWGEQGYVRVVMGVNACLLSEY 334


>sp|P07711|CATL_HUMAN CATHEPSIN L PRECURSOR (MAJOR EXCRETED PROTEIN) (MEP)
          Length = 333

 Score =  206 bits (520), Expect = 4e-53
 Identities = 125/349 (35%), Positives = 187/349 (52%), Gaps = 34/349 (9%)

Query:  8   VLAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLI 65
            +LA F + ++S  +  +   ++Q+ +++   N+ Y   E   R  +++ N+  IE  N  
Sbjct:  6   ILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQE 65

Query:  66  AINHKADTKFGVNKFADLSSDEFK---NYYLNNKEAIFTDDLPVADYLDDEFINSIPPEE 122
                K      +N F D++S+EF+   N + N K                 F   +  E 
Sbjct:  66  YREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPR-----------KGKVFQEPLFYEA 114

Query:  123 QTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECM 182
              + DWR +G VTPVKNQGQCGSCW+FS TG +EGQ F    +L+SLSEQNLVDC     
Sbjct:  115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDC----- 169

Query:  183 EYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAK 242
pattern 237                                                       ****
               G +  +EGCNGGL   A+ Y+  NGG+ +E SYPY A T   C +N         A 
Sbjct:  170 --SGPQG-NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEA-TEESCKYNP----KYSVAN 221

Query:  243 ISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIV 299
             + F  IPK E  +   + + GP+++A DA    + FY  G+ F+  C+   +DHG+L+V
Sbjct:  222 DTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVV 281

Query:  300 GYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVS 347
            GY  ++T    N  YW+VKNSWG +WG  GY+ + +  +N CG+++  S
Sbjct:  282 GYGFEST-ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAAS 329


>sp|Q28944|CATL_PIG CATHEPSIN L PRECURSOR
          Length = 334

 Score =  206 bits (519), Expect = 5e-53
 Identities = 121/316 (38%), Positives = 167/316 (52%), Gaps = 33/316 (10%)

Query:  40  YSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFK---NYYLNNK 96
            Y   E   R  +++ N+  IE  N      K      +N F D++++EF+   N + N K
Sbjct:  40  YGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQK 99

Query:  97  EAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVE 156
                             F  S+  E   + DWR +G VT VKNQGQCGSCW+FS TG +E
Sbjct:  100 HK-----------KGKVFHESLVLEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALE 148

Query:  157 GQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTES 216
            GQ F    KLVSLSEQNLVDC       +G    ++GCNGGL  NA+ Y+  NGG+ TE 
Sbjct:  149 GQMFRKTGKLVSLSEQNLVDCSRP----QG----NQGCNGGLMDNAFQYVKDNGGLDTEE 200

Query:  217 SYPYTAETGTQCNFNSANIGPE-EQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--V 273
pattern 237                     ** **
            SYPY       C +      PE   A  + F  IP+ E  +   + + GP+++A DA   
Sbjct:  201 SYPYLGRETNSCTYK-----PECSAANDTGFVDIPQREKALMKAVATVGPISVAIDAGHS 255

Query:  274 EWQFYIGGV-FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIY 332
             +QFY  G+ +D  C+   LDHG+L+VGY  + T    +  +WIVKNSWG +WG  GY+ 
Sbjct:  256 SFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGT-DSNSSKFWIVKNSWGPEWGWNGYVK 314

Query:  333 LRRGKNT-CGVSNFVS 347
            + + +N  CG+S   S
Sbjct:  315 MAKDQNNHCGISTAAS 330


>sp|P00785|ACTN_ACTCH ACTINIDAIN PRECURSOR (ACTINIDIN)
          Length = 380

 Score =  204 bits (513), Expect = 3e-52
 Identities = 124/334 (37%), Positives = 178/334 (53%), Gaps = 41/334 (12%)

Query:  24  EEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADT----KFGVN 78
            E ++ +  +  K+ K Y S  E+  RFEIFK  L  I+E       H ADT    K G+N
Sbjct:  37  EVKAMYESWLIKYGKSYNSLGEWERRFEIFKETLRFIDE-------HNADTNRSYKVGLN 89

Query:  79  KFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVK 138
            +FADL+ +EF++ YL       ++   V++  +  F   +P    +  DWR+ GAV  +K
Sbjct:  90  QFADLTDEEFRSTYLGFTSG--SNKTKVSNRYEPRFGQVLP----SYVDWRSAGAVVDIK 143

Query:  139 NQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGL 198
            +QG+CG CW+FS    VEG + I    L+SLSEQ L+DC        G      GCNGG 
Sbjct:  144 SQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDC--------GRTQNTRGCNGGY 195

Query:  199 QPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAG 258
pattern 237                                       ****
              + + +II NGGI TE +YPYTA+ G +CN +  N   E+   I  +  +P N      
Sbjct:  196 ITDGFQFIINNGGINTEENYPYTAQDG-ECNLDLQN---EKYVTIDTYENVPYNNEWALQ 251

Query:  259 YIVSTGPLAIAADAV--EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWI 316
              V+  P+++A DA    ++ Y  G+F  PC   ++DH + IVGY  +  I      YWI
Sbjct:  252 TAVTYQPVSVALDAAGDAFKHYSSGIFTGPCG-TAIDHAVTIVGYGTEGGI-----DYWI 305

Query:  317 VKNSWGADWGEQGYIYLRR---GKNTCGVSNFVS 347
            VKNSW   WGE+GY+ + R   G  TCG++   S
Sbjct:  306 VKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPS 339


>sp|P25803|CYSP_PHAVU VIGNAIN PRECURSOR (BEAN ENDOPEPTIDASE) (CYSTEINE PROTEINASE EP-C1)
          Length = 362

 Score =  203 bits (510), Expect = 6e-52
 Identities = 125/313 (39%), Positives = 177/313 (55%), Gaps = 35/313 (11%)

Query:  47  ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNK---EAIFTDD 103
            +RF +FK+NL  +   N +   +K      +NKFAD+++ EF++ Y  +K     +F   
Sbjct:  58  KRFNVFKANLMHVHNTNKMDKPYKLK----LNKFADMTNHEFRSTYAGSKVNHPRMFRGT 113

Query:  104 LPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 163
                     E + S+PP    + DWR +GAVT VK+QGQCGSCW+FST   VEG + I  
Sbjct:  114 PHENGAFMYEKVVSVPP----SVDWRKKGAVTDVKDQGQCGSCWAFSTVVAVEGINQIKT 169

Query:  164 NKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAE 223
            NKLV+LSEQ LVDCD E          ++GCNGGL  +A+ +I + GGI TES+YPY A+
Sbjct:  170 NKLVALSEQELVDCDKE---------ENQGCNGGLMESAFEFIKQKGGITTESNYPYKAQ 220

Query:  224 TGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGG 281
pattern 237              ****
             GT C+ +  N   +    I     +P N+       V+  P+++A DA   ++QFY  G
Sbjct:  221 EGT-CDASKVN---DLAVSIDGHENVPANDEDALLKAVANQPVSVAIDAGGSDFQFYSEG 276

Query:  282 VFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----K 337
            VF   C+   L+HG+ IVGY    T+   N  YWIV+NSWG +WGE GYI ++R     +
Sbjct:  277 VFTGDCS-TDLNHGVAIVGYG--TTVDGTN--YWIVRNSWGPEWGEHGYIRMQRNISKKE 331

Query:  338 NTCGVSNFVSTSI 350
              CG++   S  I
Sbjct:  332 GLCGIAMLPSYPI 344


>sp|Q10991|CATL_SHEEP CATHEPSIN L
          Length = 217

 Score =  201 bits (507), Expect = 1e-51
 Identities = 105/226 (46%), Positives = 139/226 (61%), Gaps = 23/226 (10%)

Query:  127 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEG 186
            DW  +G VTPVKNQGQCGSCW+FS TG +EGQ F    KLVSLSEQNLVD          
Sbjct:  6   DWTKKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVD--------SS 57

Query:  187 EEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPE-EQAKISN 245
pattern 237                                                   ** **
                ++GCNGGL  NA+ YI +NGG+ +E SYPY A T T CN+      PE   AK + 
Sbjct:  58  RPQGNQGCNGGLMDNAFQYIKENGGLDSEESYPYEA-TDTSCNYK-----PEYSAAKDTG 111

Query:  246 FTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVGYS 302
            F  IP+ E  +   + + GP+++A DA    +QFY  G+ +D  C+   LDHG+L+VGY 
Sbjct:  112 FVDIPQREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYG 171

Query:  303 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVS 347
             + T    N  +WIVKNSWG +WG +GY+ + + +N  CG++   S
Sbjct:  172 FEGT----NNKFWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAAS 213


>sp|P43156|CYSP_HEMSP THIOL PROTEASE SEN102 PRECURSOR
          Length = 360

 Score =  201 bits (506), Expect = 2e-51
 Identities = 121/307 (39%), Positives = 161/307 (52%), Gaps = 28/307 (9%)

Query:  43  EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTD 102
            +E   RF +FK N+  I E N       A  K  +NKF D+++ EF++ Y  +K      
Sbjct:  54  DEKNRRFNVFKENVKFIHEFNQ---KKDAPYKLALNKFGDMTNQEFRSKYAGSKIQHHRS 110

Query:  103 DLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFIS 162
               +          ++      + DWR +GAVT VK+QGQCGSCW+FST  +VEG + I 
Sbjct:  111 QRGIQKNTGSFMYENVGSLPAASIDWRAKGAVTGVKDQGQCGSCWAFSTIASVEGINQIK 170

Query:  163 QNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTA 222
              +LVSLSEQ LVDCD          + +EGCNGGL   A+ +I KN GI TE SYPY  
Sbjct:  171 TGELVSLSEQELVDCD---------TSYNEGCNGGLMDYAFEFIQKN-GITTEDSYPYAE 220

Query:  223 ETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIG 280
pattern 237               ****
            + GT C  N  N        I     +P N        V+  P++++ +A    +QFY  
Sbjct:  221 QDGT-CASNLLN---SPVVSIDGHQDVPANNENALMQAVANQPISVSIEASGYGFQFYSE 276

Query:  281 GVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG---- 336
            GVF   C    LDHG+ IVGY A     R    YWIVKNSWG +WGE GYI ++RG    
Sbjct:  277 GVFTGRCG-TELDHGVAIVGYGAT----RDGTKYWIVKNSWGEEWGESGYIRMQRGISDK 331

Query:  337 KNTCGVS 343
            +  CG++
Sbjct:  332 RGKCGIA 338


>sp|P54639|CYS4_DICDI CYSTEINE PROTEINASE 4 PRECURSOR
          Length = 442

 Score =  200 bits (504), Expect = 3e-51
 Identities = 117/308 (37%), Positives = 169/308 (53%), Gaps = 32/308 (10%)

Query:  4   ILLFVLAVFTVFVSSRGIPPEEQ--SQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEE 61
            +L F+  +   + S++    E Q  + F  +     + YS EE+  R++IFKSN+  + +
Sbjct:  3   VLSFLCLLLVSYASAKQQFSELQYRNAFTNWMQAHQRTYSSEEFNARYQIFKSNMDYVHQ 62

Query:  62  LNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPE 121
             N    +   +T  G+N FAD+++ E++  YL      F     +    ++E I S P  
Sbjct:  63  WN----SKGGETVLGLNVFADITNQEYRTTYLGTP---FDGSALIGT--EEEKIFSTPAP 113

Query:  122 EQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFI---SQNKLVSLSEQNLVDCD 178
                 DWR +GAVTP+KNQGQCG CWSFSTTG+ EG HFI   ++  LVSLSEQNL+DC 
Sbjct:  114 ---TVDWRAQGAVTPIKNQGQCGGCWSFSTTGSTEGAHFIASGTKKDLVSLSEQNLIDC- 169

Query:  179 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPE 238
pattern 237                                                           **
                    +   + GC GGL    + YII N GI TESSYPYTAE G +C F ++NIG  
Sbjct:  170 -------SKSYGNNGCEGGLMTLGFEYIINNKGIDTESSYPYTAEDGKECKFKTSNIG-- 220

Query:  239 EQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHG 295
pattern 239 **
              A+I ++  +            +  P+++A DA    +Q Y  G++  P C P  LDHG
Sbjct:  221 --AQIVSYQNVTSGSEASLQSASNNAPVSVAIDASNESFQLYESGIYYEPACTPTQLDHG 278

Query:  296 ILIVGYSA 303
            +L+VGY +
Sbjct:  279 VLVVGYGS 286


 Score = 48.8 bits (114), Expect = 2e-05
 Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query: 314 YWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 347
           YWIVKNSWG  WG  GYI++ + + N CG++   S
Sbjct: 401 YWIVKNSWGTSWGMDGYIFMSKDRNNNCGIATMAS 435


>sp|O60911|CATM_HUMAN CATHEPSIN L2 PRECURSOR (CATHEPSIN V)
          Length = 334

 Score =  199 bits (501), Expect = 7e-51
 Identities = 127/357 (35%), Positives = 191/357 (52%), Gaps = 43/357 (12%)

Query:  5   LLFVLAVFTVFVSSRGIPPEEQS---QFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEE 61
            L  VLA F + ++S  +P  +Q+   ++ +++    + Y   E   R  +++ N+  IE 
Sbjct:  3   LSLVLAAFCLGIAS-AVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIEL 61

Query:  62  LNLIAINHKADTKFGVNKFADLSSDEFKNY---YLNNK---EAIFTDDLPVADYLDDEFI 115
             N      K      +N F D++++EF+     + N K     +F + L    +LD    
Sbjct:  62  HNGEYSQGKHGFTMAMNAFPDMTNEEFRQMMGCFRNQKFRKGKVFREPL----FLD---- 113

Query:  116 NSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLV 175
              +P     + DWR +G VTPVKNQ QCGSCW+FS TG +EGQ F    KLVSLSEQNLV
Sbjct:  114 --LPK----SVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLV 167

Query:  176 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANI 235
            DC       +G    ++GCNGG    A+ Y+ +NGG+ +E SYPY A     C +   N 
Sbjct:  168 DCSRP----QG----NQGCNGGFMARAFQYVKENGGLDSEESYPYVA-VDEICKYRPEN- 217

Query:  236 GPEEQAKISNFTMI-PKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNS 291
pattern 237  ****
                 A  + FT++ P  E  +   + + GP+++A DA    +QFY  G+ F+  C+  +
Sbjct:  218 ---SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKN 274

Query:  292 LDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-CGVSNFVS 347
            LDHG+L+VGY  +      N  YW+VKNSWG +WG  GY+ + + KN  CG++   S
Sbjct:  275 LDHGVLVVGYGFEGA-NSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAAS 330


>sp|O10364|CATV_NPVOP VIRAL CATHEPSIN (V-CATH)
          Length = 324

 Score =  196 bits (494), Expect = 5e-50
 Identities = 116/322 (36%), Positives = 168/322 (52%), Gaps = 30/322 (9%)

Query:  29  FLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
            F +F  KFNK YS E E L RF+IF+ NL +I   N     + +  ++ +NKF+DLS +E
Sbjct:  28  FEDFLHKFNKNYSSESEKLHRFKIFQHNLEEIINKN----QNDSTAQYEINKFSDLSKEE 83

Query:  88  FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCW 147
              + Y        T +      LD       P      FDWR    VT VKNQG CG+CW
Sbjct:  84  AISKYTGLSLPHQTQNFCEVVILDRP-----PDRGPLEFDWRQFNKVTSVKNQGVCGACW 138

Query:  148 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 207
            +F+T G++E Q  I  N+L++LSEQ  +DCD            + GC+GGL   A+   +
Sbjct:  139 AFATLGSLESQFAIKYNRLINLSEQQFIDCDR----------VNAGCDGGLLHTAFESAM 188

Query:  208 KNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLA 267
pattern 237                              ****
            + GG+Q ES YPY    G QC  N        ++      M    E  +   + + GP+ 
Sbjct:  189 EMGGVQMESDYPYETANG-QCRINPNRFVVGVRSCRRYIVMF---EEKLKDLLRAVGPIP 244

Query:  268 IAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 327
            +A DA +   Y  G+    C  + L+H +L+VGY+ +N     N+PYWI+KN+WG DWGE
Sbjct:  245 VAIDASDIVNYRRGIMR-QCANHGLNHAVLLVGYAVEN-----NIPYWILKNTWGTDWGE 298

Query:  328 QGYIYLRRGKNTCGVSNFVSTS 349
             GY  +++  N CG+ N + +S
Sbjct:  299 DGYFRVQQNINACGIRNELVSS 320


>sp|P25777|ORYB_ORYSA ORYZAIN BETA CHAIN PRECURSOR
          Length = 471

 Score =  196 bits (494), Expect = 5e-50
 Identities = 115/310 (37%), Positives = 166/310 (53%), Gaps = 31/310 (10%)

Query:  44  EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDD 103
            E+  RF +F  NL  ++  N  A +     + G+N+FADL+++EF+  +L  K A     
Sbjct:  69  EHERRFLVFWDNLKFVDAHNARA-DEGGGFRLGMNRFADLTNEEFRATFLGAKVA--ERS 125

Query:  104 LPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ 163
                +    + +  +P     + DWR +GAV PVKNQGQCGSCW+FS    VE  + +  
Sbjct:  126 RAAGERYRHDGVEELPE----SVDWREKGAVAPVKNQGQCGSCWAFSAVSTVESINQLVT 181

Query:  164 NKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAE 223
             ++++LSEQ LV+C             + GCNGGL  +A+++IIKNGGI TE  YPY A 
Sbjct:  182 GEMITLSEQELVEC--------STNGQNSGCNGGLMADAFDFIIKNGGIDTEDDYPYKAV 233

Query:  224 TGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGG 281
pattern 237              ****
             G +C+ N  N    +   I  F  +P+N+       V+  P+++A +A   E+Q Y  G
Sbjct:  234 DG-KCDINREN---AKVVSIDGFEDVPQNDEKSLQKAVAHQPVSVAIEAGGREFQLYHSG 289

Query:  282 VFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT-- 339
            VF   C   SLDHG++ VGY   N        YWIV+NSWG  WGE GY+ + R  N   
Sbjct:  290 VFSGRCG-TSLDHGVVAVGYGTDN-----GKDYWIVRNSWGPKWGESGYVRMERNINVTT 343

Query:  340 --CGVSNFVS 347
              CG++   S
Sbjct:  344 GKCGIAMMAS 353


>sp|P25776|ORYA_ORYSA ORYZAIN ALPHA CHAIN PRECURSOR
          Length = 458

 Score =  194 bits (488), Expect = 2e-49
 Identities = 124/355 (34%), Positives = 183/355 (50%), Gaps = 43/355 (12%)

Query:  3   VILLFVLAVFTVFVSSRGIPPEEQSQ--FLEFQDKFNKKYSHE-EYLERFEIFKSNLGKI 59
            ++LL  LA   + + S G   EE+++  + E++ +  K Y+   E   R+  F+ NL  I
Sbjct:  12  LLLLLSLAAADMSIVSYGERSEEEARRLYAEWKAEHGKSYNAVGEEERRYAAFRDNLRYI 71

Query:  60  EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN-----NKEAIFTDDLPVADYLDDEF 114
            +E N  A       + G+N+FADL+++E+++ YL       +E   +D    AD      
Sbjct:  72  DEHNAAADAGVHSFRLGLNRFADLTNEEYRDTYLGLRNKPRRERKVSDRYLAAD------ 125

Query:  115 INSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNL 174
             N   PE   + DWRT+GAV  +K+QG CGSCW+FS    VE  + I    L+SLSEQ L
Sbjct:  126 -NEALPE---SVDWRTKGAVAEIKDQGGCGSCWAFSAIAAVEDINQIVTGDLISLSEQEL 181

Query:  175 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSAN 234
            VDCD          + +EGCNGGL   A+++II NGGI TE  YPY  +   +C+ N  N
Sbjct:  182 VDCD---------TSYNEGCNGGLMDYAFDFIINNGGIDTEDDYPYKGK-DERCDVNRKN 231

Query:  235 IGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSL 292
pattern 237   ****
                +   I ++  +  N        V   P+++A +A    +Q Y  G+F   C   +L
Sbjct:  232 ---AKVVTIDSYEDVTPNSETSLQKAVRNQPVSVAIEAGGRAFQLYSSGIFTGKCG-TAL 287

Query:  293 DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR----GKNTCGVS 343
            DHG+  VGY  +N        YWIV+NSWG  WGE GY+ + R        CG++
Sbjct:  288 DHGVAAVGYGTEN-----GKDYWIVRNSWGKSWGESGYVRMERNIKASSGKCGIA 337


>sp|P43297|RD21_ARATH CYSTEINE PROTEINASE RD21A PRECURSOR
          Length = 462

 Score =  193 bits (486), Expect = 4e-49
 Identities = 122/321 (38%), Positives = 168/321 (52%), Gaps = 43/321 (13%)

Query:  35  KFNKKYSHEEYLE---RFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNY 91
            K  K  S    +E   RFEIFK NL  ++E N   ++++     G+ +FADL++DE+++ 
Sbjct:  56  KHGKAQSQNSLVEKDRRFEIFKDNLRFVDEHNEKNLSYR----LGLTRFADLTNDEYRSK 111

Query:  92  YLN---NKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWS 148
            YL     K+      L     + DE   SI        DWR +GAV  VK+QG CGSCW+
Sbjct:  112 YLGAKMEKKGERRTSLRYEARVGDELPESI--------DWRKKGAVAEVKDQGGCGSCWA 163

Query:  149 FSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK 208
            FST G VEG + I    L++LSEQ LVDCD          + +EGCNGGL   A+ +IIK
Sbjct:  164 FSTIGAVEGINQIVTGDLITLSEQELVDCD---------TSYNEGCNGGLMDYAFEFIIK 214

Query:  209 NGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAI 268
pattern 237                             ****
            NGGI T+  YPY    GT C+    N    +   I ++  +P          V+  P++I
Sbjct:  215 NGGIDTDKDYPYKGVDGT-CDQIRKN---AKVVTIDSYEDVPTYSEESLKKAVAHQPISI 270

Query:  269 AADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 326
            A +A    +Q Y  G+FD  C    LDHG++ VGY  +N        YWIV+NSWG  WG
Sbjct:  271 AIEAGGRAFQLYDSGIFDGSCG-TQLDHGVVAVGYGTEN-----GKDYWIVRNSWGKSWG 324

Query:  327 EQGYIYLRR----GKNTCGVS 343
            E GY+ + R        CG++
Sbjct:  325 ESGYLRMARNIASSSGKCGIA 345


>sp|Q10717|CYS2_MAIZE CYSTEINE PROTEINASE 2 PRECURSOR
          Length = 360

 Score =  193 bits (485), Expect = 5e-49
 Identities = 115/329 (34%), Positives = 172/329 (51%), Gaps = 32/329 (9%)

Query:  28  QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
            +F  F  ++ K Y S  E  +RF IF  +L  +   N   ++++     G+N+FAD+S +
Sbjct:  58  RFARFAVRYGKSYESAAEVHKRFRIFSESLQLVRSTNRKGLSYR----LGINRFADMSWE 113

Query:  87  EFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSC 146
            EF+   L   +         A    +  + +         DWR  G V+PVKNQG CGSC
Sbjct:  114 EFRATRLGAAQNCS------ATLTGNHRMRAAAVALPETKDWREDGIVSPVKNQGHCGSC 167

Query:  147 WSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI 206
            W+FSTTG +E  +  +  K +SLSEQ LVDC      +        GCNGGL   A+ YI
Sbjct:  168 WTFSTTGALEAAYTQATGKPISLSEQQLVDCGFAFNNF--------GCNGGLPSQAFEYI 219

Query:  207 IKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPL 266
pattern 237                               ****
              NGG+ TE SYPY    G  C F + N+G +    + N T+  ++E   A  +V   P+
Sbjct:  220 KYNGGLDTEESYPYQGVNGI-CKFKNENVGVKVLDSV-NITLGAEDELKDAVGLVR--PV 275

Query:  267 AIAADAVE-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWG 322
            ++A + +  ++ Y  GV+        P  ++H +L VGY  ++      +PYW++KNSWG
Sbjct:  276 SVAFEVITGFRLYKSGVYTSDHCGTTPMDVNHAVLAVGYGVED-----GVPYWLIKNSWG 330

Query:  323 ADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            ADWG++GY  +  GKN CGV+   S  I+
Sbjct:  331 ADWGDEGYFKMEMGKNMCGVATCASYPIV 359


>sp|P14080|PAP2_CARPA CHYMOPAPAIN PRECURSOR (PAPAYA PROTEINASE II) (PPII)
          Length = 352

 Score =  192 bits (482), Expect = 1e-48
 Identities = 128/319 (40%), Positives = 169/319 (52%), Gaps = 43/319 (13%)

Query:  35  KFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKFADLSSDEFKNY 91
            K NK Y S +E + RFEIF+ NL  I+E N      K +  +  G+N FADLS+DEFK  
Sbjct:  54  KHNKIYESIDEKIYRFEIFRDNLMYIDETN------KKNNSYWLGLNGFADLSNDEFKKK 107

Query:  92  YLNNKEAIFTDDLPVADYLDDE-FINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFS 150
            Y+        +D    ++ D+E F          + DWR +GAVTPVKNQG CGSCW+FS
Sbjct:  108 YVG----FVAEDFTGLEHFDNEDFTYKHVTNYPQSIDWRAKGAVTPVKNQGACGSCWAFS 163

Query:  151 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 210
            T   VEG + I    L+ LSEQ LVDCD              GC GG Q  +  Y + N 
Sbjct:  164 TIATVEGINKIVTGNLLELSEQELVDCDKH----------SYGCKGGYQTTSLQY-VANN 212

Query:  211 GIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKN-ETVMAGYIVSTGPLAIA 269
pattern 237                           ****
            G+ T   YPY A+   +C    A   P  + KI+ +  +P N ET   G + +  PL++ 
Sbjct:  213 GVHTSKVYPYQAKQ-YKCR---ATDKPGPKVKITGYKRVPSNCETSFLGALANQ-PLSVL 267

Query:  270 ADA--VEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 327
             +A    +Q Y  GVFD PC    LDH +  VGY   +    KN  Y I+KNSWG +WGE
Sbjct:  268 VEAGGKPFQLYKSGVFDGPCG-TKLDHAVTAVGYGTSD---GKN--YIIIKNSWGPNWGE 321

Query:  328 QGYIYLRR----GKNTCGV 342
            +GY+ L+R     + TCGV
Sbjct:  322 KGYMRLKRQSGNSQGTCGV 340


>sp|P00786|CATH_RAT CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPSIN BA)
          Length = 333

 Score =  192 bits (482), Expect = 1e-48
 Identities = 121/333 (36%), Positives = 173/333 (51%), Gaps = 38/333 (11%)

Query:  25  EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
            E+  F  +  +  K YS  EY  R ++F +N  KI+  N    NH    K G+N+F+D+S
Sbjct:  29  EKFHFTSWMKQHQKTYSSREYSHRLQVFANNWRKIQAHN--QRNHTF--KMGLNQFSDMS 84

Query:  85  SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRG-AVTPVKNQGQC 143
              E K+ YL ++                 ++    P   ++ DWR +G  V+PVKNQG C
Sbjct:  85  FAEIKHKYLWSEPQN-------CSATKSNYLRGTGPYP-SSMDWRKKGNVVSPVKNQGAC 136

Query:  144 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 203
            GSCW+FSTTG +E    I+  K+++L+EQ LVDC         +   + GC GGL   A+
Sbjct:  137 GSCWTFSTTGALESAVAIASGKMMTLAEQQLVDC--------AQNFNNHGCQGGLPSQAF 188

Query:  204 NYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQ-AKISNFTMIPKN-ETVMAGYIV 261
pattern 237                                  ****
             YI+ N GI  E SYPY  + G QC FN     PE+  A + N   I  N E  M   + 
Sbjct:  189 EYILYNKGIMGEDSYPYIGKNG-QCKFN-----PEKAVAFVKNVVNITLNDEAAMVEAVA 242

Query:  262 STGPLAIAADAVE-WQFYIGGVFDI-PCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIV 317
               P++ A +  E +  Y  GV+    C+  P+ ++H +L VGY  +N +      YWIV
Sbjct:  243 LYNPVSFAFEVTEDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYGEQNGLL-----YWIV 297

Query:  318 KNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 350
            KNSWG++WG  GY  + RGKN CG++   S  I
Sbjct:  298 KNSWGSNWGNNGYFLIERGKNMCGLAACASYPI 330


>sp|P25251|CYS4_BRANA CYSTEINE PROTEINASE COT44 PRECURSOR
          Length = 328

 Score =  190 bits (477), Expect = 5e-48
 Identities = 114/304 (37%), Positives = 164/304 (53%), Gaps = 29/304 (9%)

Query:  47  ERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPV 106
            ERF IFK NL  I+  N    N  A  K G+  FA+L++DE+++ YL  +       +  
Sbjct:  27  ERFNIFKDNLRFIDLHN--ENNKNATYKLGLTIFANLTNDEYRSLYLGARTEPVRR-ITK 83

Query:  107 ADYLDDEFINSIPPEE-QTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNK 165
            A  ++ ++  ++  +E     DWR +GAV  +K+QG CGSCW+FST   VEG + I   +
Sbjct:  84  AKNVNMKYSAAVNVDEVPVTVDWRQKGAVNAIKDQGTCGSCWAFSTAAAVEGINKIVTGE 143

Query:  166 LVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETG 225
            LVSLSEQ LVDCD         ++ ++GCNGGL   A+ +I+KNGG+ TE  YPY    G
Sbjct:  144 LVSLSEQELVDCD---------KSYNQGCNGGLMDYAFQFIMKNGGLNTEKDYPYHGTNG 194

Query:  226 TQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVF 283
pattern 237            ****
             +CN    N        I  +  +P  +       VS  P+++A DA    +Q Y  G+F
Sbjct:  195 -KCNSLLKN---SRVVTIDGYEDVPSKDETALKRAVSYQPVSVAIDAGGRAFQHYQSGIF 250

Query:  284 DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG----KNT 339
               C  N +DH ++ VGY ++N      + YWIV+NSWG  WGE GYI + R        
Sbjct:  251 TGKCGTN-MDHAVVAVGYGSEN-----GVDYWIVRNSWGTRWGEDGYIRMERNVASKSGK 304

Query:  340 CGVS 343
            CG++
Sbjct:  305 CGIA 308


>sp|P09668|CATH_HUMAN CATHEPSIN H PRECURSOR
          Length = 335

 Score =  188 bits (472), Expect = 2e-47
 Identities = 123/332 (37%), Positives = 170/332 (51%), Gaps = 36/332 (10%)

Query:  25  EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
            E+  F  +  K  K YS EEY  R + F SN  KI   N    N     K  +N+F+D+S
Sbjct:  31  EKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHN----NGNHTFKMALNQFSDMS 86

Query:  85  SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGA-VTPVKNQGQC 143
              E K+ YL ++          ++YL        PP    + DWR +G  V+PVKNQG C
Sbjct:  87  FAEIKHKYLWSEPQ--NCSATKSNYLRGT--GPYPP----SVDWRKKGNFVSPVKNQGAC 138

Query:  144 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 203
            GSCW+FSTTG +E    I+  K++SL+EQ LVDC  +   Y        GC GGL   A+
Sbjct:  139 GSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNY--------GCQGGLPSQAF 190

Query:  204 NYIIKNGGIQTESSYPYTAETGTQCNFNSAN-IGPEEQAKISNFTMIPKNETVMAGYIVS 262
pattern 237                                   ****
             YI+ N GI  E +YPY  + G  C F     IG  +   ++N T+   +E  M   +  
Sbjct:  191 EYILYNKGIMGEDTYPYQGKDG-YCKFQPGKAIGFVKD--VANITIY--DEEAMVEAVAL 245

Query:  263 TGPLAIAADAV-EWQFYIGGVF-DIPCN--PNSLDHGILIVGYSAKNTIFRKNMPYWIVK 318
              P++ A +   ++  Y  G++    C+  P+ ++H +L VGY  KN I     PYWIVK
Sbjct:  246 YNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGI-----PYWIVK 300

Query:  319 NSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 350
            NSWG  WG  GY  + RGKN CG++   S  I
Sbjct:  301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPI 332


>sp|P10056|PAP3_CARPA CARICAIN PRECURSOR (PAPAYA PROTEINASE OMEGA) (PAPAYA PROTEINASE III)
            (PPIII) (PAPAYA PEPTIDASE A)
          Length = 348

 Score =  187 bits (471), Expect = 2e-47
 Identities = 121/319 (37%), Positives = 161/319 (49%), Gaps = 38/319 (11%)

Query:  37  NKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKFADLSSDEFKNYYL 93
            NK Y + +E L RFEIFK NL  I+E N      K +  +  G+N+FADLS+DEF   Y+
Sbjct:  56  NKFYENVDEKLYRFEIFKDNLNYIDETN------KKNNSYWLGLNEFADLSNDEFNEKYV 109

Query:  94  NNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTG 153
             +       D  +    D+EFIN          DWR +GAVTPV++QG CGSCW+FS   
Sbjct:  110 GS-----LIDATIEQSYDEEFINEDTVNLPENVDWRKKGAVTPVRHQGSCGSCWAFSAVA 164

Query:  154 NVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ 213
             VEG + I   KLV LSEQ LVDC+              GC GG  P A  Y+ KN GI 
Sbjct:  165 TVEGINKIRTGKLVELSEQELVDCERR----------SHGCKGGYPPYALEYVAKN-GIH 213

Query:  214 TESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV 273
pattern 237                        ****
              S YPY A+ GT C       GP    K S    +  N        ++  P+++  ++ 
Sbjct:  214 LRSKYPYKAKQGT-CRAKQVG-GP--IVKTSGVGRVQPNNEGNLLNAIAKQPVSVVVESK 269

Query:  274 --EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 331
               +Q Y GG+F+ PC    +DH +  VGY            Y ++KNSWG  WGE+GYI
Sbjct:  270 GRPFQLYKGGIFEGPCG-TKVDHAVTAVGYGKSG-----GKGYILIKNSWGTAWGEKGYI 323

Query:  332 YLRRGK-NTCGVSNFVSTS 349
             ++R   N+ GV     +S
Sbjct:  324 RIKRAPGNSPGVCGLYKSS 342


>sp|P25778|ORYC_ORYSA ORYZAIN GAMMA CHAIN PRECURSOR
          Length = 362

 Score =  187 bits (471), Expect = 2e-47
 Identities = 112/329 (34%), Positives = 170/329 (51%), Gaps = 33/329 (10%)

Query:  28  QFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
            +F  F  +  K+Y    E   RF IF  +L  +   N   + ++     G+N+FAD+S +
Sbjct:  61  RFARFAVRHGKRYGDAAEVQRRFRIFSESLELVRSTNRRGLPYR----LGINRFADMSWE 116

Query:  87  EFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSC 146
            EF+   L   +         A    +  +   P   +T  DWR  G V+PVK+QG CGSC
Sbjct:  117 EFQASRLGAAQNCS------ATLAGNHRMRDAPALPETK-DWREDGIVSPVKDQGHCGSC 169

Query:  147 WSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI 206
            W FSTTG++E ++  +    VSLSEQ L DC      +        GC+GGL   A+ YI
Sbjct:  170 WPFSTTGSLEARYTQATGPPVSLSEQQLADCATRYNNF--------GCSGGLPSQAFEYI 221

Query:  207 IKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPL 266
pattern 237                               ****
              NGG+ TE +YPYT   G  C++   N G +    + N T++ ++E   A  +V   P+
Sbjct:  222 KYNGGLDTEEAYPYTGVNGI-CHYKPENAGVKVLDSV-NITLVAEDELKNAVGLVR--PV 277

Query:  267 AIAADAVE-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWG 322
            ++A   +  ++ Y  GV+       +P  ++H +L VGY  +N      +PYW++KNSWG
Sbjct:  278 SVAFQVINGFRMYKSGVYTSDHCGTSPMDVNHAVLAVGYGVEN-----GVPYWLIKNSWG 332

Query:  323 ADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            ADWG+ GY  +  GKN CG++   S  I+
Sbjct:  333 ADWGDNGYFTMEMGKNMCGIATCASYPIV 361


>sp|P15242|TES1_RAT TESTIN 1/2 PRECURSOR (CMB-22/CMB-23)
          Length = 333

 Score =  187 bits (469), Expect = 4e-47
 Identities = 115/356 (32%), Positives = 184/356 (51%), Gaps = 30/356 (8%)

Query:  3   VILLFVLAVFTVFVSSRGIPPEEQS--QFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
            +I +  LA+  + V S    P+     ++ E++ K  K Y+  E   +  +++ N   IE
Sbjct:  1   MIAVLFLAILCLEVDSTAPTPDPSLDVEWNEWRTKHGKTYNMNEERLKRAVWEKNFKMIE 60

Query:  61  ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLN-NKEAIFTDDLPVADYLDDEFINSIP 119
              N   +  + D    +N F DL++ EF        ++ I    +    + D +F+  +P
Sbjct:  61  LHNWEYLEGRHDFTMAMNAFGDLTNIEFVKMMTGFQRQKIKKTHI----FQDHQFLY-VP 115

Query:  120 PEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDH 179
                   DWR  G VTPVKNQG C S W+FS TG++EGQ F    +L+ LSEQNL+DC  
Sbjct:  116 KR----VDWRQLGYVTPVKNQGHCASSWAFSATGSLEGQMFRKTERLIPLSEQNLLDCMG 171

Query:  180 ECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEE 239
pattern 237                                                          ***
              + +        GC+GG    A+ Y+  NGG+ TE SYPY  + G +C +++ N     
Sbjct:  172 SNVTH--------GCSGGFMQYAFQYVKDNGGLATEESYPYRGQ-GRECRYHAEN----S 218

Query:  240 QAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV--EWQFYIGGVFDIP-CNPNSLDHGI 296
pattern 240 *
             A + +F  IP +E  +   +   GP+++A DA    +QFY  G++  P C    L+H +
Sbjct:  219 AANVRDFVQIPGSEEALMKAVAKVGPISVAVDASHGSFQFYGSGIYYEPQCKRVHLNHAV 278

Query:  297 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 351
            L+VGY  +      N  +W+VKNSWG +WG +GY+ L +   N CG++ + +  I+
Sbjct:  279 LVVGYGFEGEESDGN-SFWLVKNSWGEEWGMKGYMKLAKDWSNHCGIATYSTYPIV 333


>sp|O46427|CATH_PIG CATHEPSIN H PRECURSOR
          Length = 335

 Score =  186 bits (468), Expect = 5e-47
 Identities = 124/343 (36%), Positives = 176/343 (51%), Gaps = 42/343 (12%)

Query:  17  SSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFG 76
            S+  +   E+  F  +  +  KKYS EEY  R ++F SN  KI   N  A NH    K G
Sbjct:  23  SNLAVSSFEKLHFKSWMVQHQKKYSLEEYHHRLQVFVSNWRKINAHN--AGNHTF--KLG 78

Query:  77  VNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGA-VT 135
            +N+F+D+S DE ++ YL ++           +YL        PP    + DWR +G  V+
Sbjct:  79  LNQFSDMSFDEIRHKYLWSEPQ--NCSATKGNYLRGT--GPYPP----SMDWRKKGNFVS 130

Query:  136 PVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCN 195
            PVKNQG CGSCW+FSTTG +E    I+  K++SL+EQ LVDC         +   + GC 
Sbjct:  131 PVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDC--------AQNFNNHGCQ 182

Query:  196 GGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQ----AKISNFTMIPK 251
pattern 237                                          ****
            GGL   A+ YI  N GI  E +YPY  +    C F      P++       ++N TM   
Sbjct:  183 GGLPSQAFEYIRYNKGIMGEDTYPYKGQ-DDHCKFQ-----PDKAIAFVKDVANITM--N 234

Query:  252 NETVMAGYIVSTGPLAIAADAV-EWQFYIGGVF-DIPCN--PNSLDHGILIVGYSAKNTI 307
            +E  M   +    P++ A +   ++  Y  G++    C+  P+ ++H +L VGY  +N I
Sbjct:  235 DEEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGI 294

Query:  308 FRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 350
                 PYWIVKNSWG  WG  GY  + RGKN CG++   S  I
Sbjct:  295 -----PYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPI 332


>sp|P05167|ALEU_HORVU THIOL PROTEASE ALEURAIN PRECURSOR
          Length = 362

 Score =  185 bits (466), Expect = 9e-47
 Identities = 111/329 (33%), Positives = 169/329 (50%), Gaps = 33/329 (10%)

Query:  28  QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSD 86
            +F  F  ++ K Y S  E   RF IF  +L ++   N   + ++     G+N+F+D+S +
Sbjct:  60  RFARFAVRYGKSYESAAEVRRRFRIFSESLEEVRSTNRKGLPYR----LGINRFSDMSWE 115

Query:  87  EFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSC 146
            EF+   L   +         A    +  +       +T  DWR  G V+PVKNQ  CGSC
Sbjct:  116 EFQATRLGAAQTCS------ATLAGNHLMRDAAALPETK-DWREDGIVSPVKNQAHCGSC 168

Query:  147 WSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYI 206
            W+FSTTG +E  +  +  K +SLSEQ LVDC      +        GCNGGL   A+ YI
Sbjct:  169 WTFSTTGALEAAYTQATGKNISLSEQQLVDCAGGFNNF--------GCNGGLPSQAFEYI 220

Query:  207 IKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPL 266
pattern 237                               ****
              NGGI TE SYPY    G  C++ + N   +    + N T+  ++E   A  +V   P+
Sbjct:  221 KYNGGIDTEESYPYKGVNGV-CHYKAENAAVQVLDSV-NITLNAEDELKNAVGLVR--PV 276

Query:  267 AIAADAVE-WQFYIGGVF---DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWG 322
            ++A   ++ ++ Y  GV+        P+ ++H +L VGY  +N      +PYW++KNSWG
Sbjct:  277 SVAFQVIDGFRQYKSGVYTSDHCGTTPDDVNHAVLAVGYGVEN-----GVPYWLIKNSWG 331

Query:  323 ADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            ADWG+ GY  +  GKN C ++   S  ++
Sbjct:  332 ADWGDNGYFKMEMGKNMCAIATCASYPVV 360


>sp|P43235|CATK_HUMAN CATHEPSIN K PRECURSOR (CATHEPSIN O) (CATHEPSIN X) (CATHEPSIN O2)
          Length = 329

 Score =  185 bits (465), Expect = 1e-46
 Identities = 123/350 (35%), Positives = 185/350 (52%), Gaps = 39/350 (11%)

Query:  9   LAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
            L V  + V S  + PEE   + +  ++    K+Y+++ + + R  I++ NL  I   NL 
Sbjct:  4   LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63

Query:  66  AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTA 125
            A       +  +N   D++S+E        K       +P++    ++ +  IP  E  A
Sbjct:  64  ASLGVHTYELAMNHLGDMTSEEVVQKMTGLK-------VPLSHSRSNDTLY-IPEWEGRA 115

Query:  126 ---FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECM 182
                D+R +G VTPVKNQGQCGSCW+FS+ G +EGQ      KL++LS QNLVDC  E  
Sbjct:  116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE-- 173

Query:  183 EYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAK 242
pattern 237                                                       ****
                    ++GC GG   NA+ Y+ KN GI +E +YPY  +    C +N       + AK
Sbjct:  174 --------NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQE-ESCMYNPTG----KAAK 220

Query:  243 ISNFTMIPK-NETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILI 298
               +  IP+ NE  +   +   GP+++A DA    +QFY  GV +D  CN ++L+H +L 
Sbjct:  221 CRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLA 280

Query:  299 VGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 347
            VGY       +K   +WI+KNSWG +WG +GYI + R K N CG++N  S
Sbjct:  281 VGYG-----IQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLAS 325


>sp|P05994|PAP4_CARPA PAPAYA PROTEINASE IV PRECURSOR (PPIV) (PAPAYA PEPTIDASE B) (GLYCYL
            ENDOPEPTIDASE)
          Length = 348

 Score =  184 bits (462), Expect = 3e-46
 Identities = 116/315 (36%), Positives = 162/315 (50%), Gaps = 37/315 (11%)

Query:  35  KFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYL 93
            K NK Y + +E L RFEIFK NL  I+E N +   +      G+N+F+DLS+DEFK  Y+
Sbjct:  54  KHNKNYKNVDEKLYRFEIFKDNLKYIDERNKMINGYW----LGLNEFSDLSNDEFKEKYV 109

Query:  94  NNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTG 153
             +    +T+        D+EF+N    +   + DWR +GAVTPVK+QG C SCW+FST  
Sbjct:  110 GSLPEDYTNQP-----YDEEFVNEDIVDLPESVDWRAKGAVTPVKHQGYCESCWAFSTVA 164

Query:  154 NVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ 213
             VEG + I    LV LSEQ LVDCD +            GCN G Q  +  Y+ +N GI 
Sbjct:  165 TVEGINKIKTGNLVELSEQELVDCDKQ----------SYGCNRGYQSTSLQYVAQN-GIH 213

Query:  214 TESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAV 273
pattern 237                        ****
              + YPY A+  T C  N    GP  + K +    +  N        ++  P+++  ++ 
Sbjct:  214 LRAKYPYIAKQQT-CRANQVG-GP--KVKTNGVGRVQSNNEGSLLNAIAHQPVSVVVESA 269

Query:  274 --EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 331
              ++Q Y GG+F+  C    +DH +  VGY            Y ++KNSWG  WGE GYI
Sbjct:  270 GRDFQNYKGGIFEGSCG-TKVDHAVTAVGYGKSG-----GKGYILIKNSWGPGWGENGYI 323

Query:  332 YLRRGK----NTCGV 342
             +RR        CGV
Sbjct:  324 RIRRASGNSPGVCGV 338


>sp|P25250|CYS2_HORVU CYSTEINE PROTEINASE EP-B 2 PRECURSOR
          Length = 373

 Score =  183 bits (461), Expect = 3e-46
 Identities = 125/349 (35%), Positives = 171/349 (48%), Gaps = 40/349 (11%)

Query:  8   VLAVFTVFVSSRGIPPEEQSQFLE---------FQDKFNKKYSHEEYLERFEIFKSNLGK 58
            VLAV  V + S  IP E++    E         +Q     +  H E   RF  FKSN   
Sbjct:  17  VLAVAAVELCS-AIPMEDKDLESEEALWDLYERWQSAHRVRRHHAEKHRRFGTFKSNAHF 75

Query:  59  IEELNLIAINHKADTKFGV--NKFADLSSDEFKNYYLNNKEAIFTDDLP-VADYLDDEF- 114
            I      + N + D  + +  N+F D+   EF+  ++ +         P V  ++     
Sbjct:  76  IH-----SHNKRGDHPYRLHLNRFGDMDQAEFRATFVGDLRRDTPSKPPSVPGFMYAALN 130

Query:  115 INSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNL 174
            ++ +PP    + DWR +GAVT VK+QG+CGSCW+FST  +VEG + I    LVSLSEQ L
Sbjct:  131 VSDLPP----SVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQEL 186

Query:  175 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSAN 234
            +DCD          A ++GC GGL  NA+ YI  NGG+ TE++YPY A  GT CN   A 
Sbjct:  187 IDCD---------TADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGT-CNVARAA 236

Query:  235 IGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNPNSL 292
pattern 237   ****
                    I     +P N        V+  P+++A +A    + FY  GVF   C    L
Sbjct:  237 QNSPVVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGECG-TEL 295

Query:  293 DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCG 341
            DHG+ +VGY     +      YW VKNSWG  WGEQGYI + +     G
Sbjct:  296 DHGVAVVGYG----VAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASG 340


>sp|P25249|CYS1_HORVU CYSTEINE PROTEINASE EP-B 1 PRECURSOR
          Length = 371

 Score =  183 bits (460), Expect = 5e-46
 Identities = 126/353 (35%), Positives = 170/353 (47%), Gaps = 48/353 (13%)

Query:  8   VLAVFTVFVSSRGIPPEEQSQFLE---------FQDKFNKKYSHEEYLERFEIFKSNLGK 58
            VLAV  V + S  IP E++    E         +Q     +  H E   RF  FKSN   
Sbjct:  17  VLAVAAVELCS-AIPMEDKDLESEEALWDLYERWQSAHRVRRHHAEKHRRFGTFKSNAHF 75

Query:  59  IEELNLIAINHKADTKFGV--NKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEF-- 114
            I      + N + D  + +  N+F D+   EF+  ++ +       D P        F  
Sbjct:  76  IH-----SHNKRGDHPYRLHLNRFGDMDQAEFRATFVGDLRR----DTPAKPPSVPGFMY 126

Query:  115 ----INSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLS 170
                ++ +PP    + DWR +GAVT VK+QG+CGSCW+FST  +VEG + I    LVSLS
Sbjct:  127 AALNVSDLPP----SVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLS 182

Query:  171 EQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNF 230
            EQ L+DCD          A ++GC GGL  NA+ YI  NGG+ TE++YPY A  GT CN 
Sbjct:  183 EQELIDCD---------TADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGT-CNV 232

Query:  231 NSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCN 288
pattern 237       ****
              A         I     +P N        V+  P+++A +A    + FY  GVF   C 
Sbjct:  233 ARAAQNSPVVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGDCG 292

Query:  289 PNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCG 341
               LDHG+ +VGY     +      YW VKNSWG  WGEQGYI + +     G
Sbjct:  293 -TELDHGVAVVGYG----VAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASG 340


>sp|P43236|CATK_RABIT CATHEPSIN K PRECURSOR (OC-2 PROTEIN)
          Length = 329

 Score =  183 bits (459), Expect = 6e-46
 Identities = 119/348 (34%), Positives = 181/348 (51%), Gaps = 35/348 (10%)

Query:  9   LAVFTVFVSSRGIPPEE--QSQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
            L V  + V S  + PEE   +Q+  ++  ++K+Y+ + + + R  I++ NL  I   NL 
Sbjct:  4   LKVLLLPVVSFALHPEEILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLE 63

Query:  66  AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDE-FINSIPPEEQT 124
            A       +  +N   D++S+E        K        P   + +D  +I         
Sbjct:  64  ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVP------PSRSHSNDTLYIPDWEGRTPD 117

Query:  125 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 184
            + D+R +G VTPVKNQGQCGSCW+FS+ G +EGQ      KL++LS QNLVDC  E    
Sbjct:  118 SIDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE---- 173

Query:  185 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKIS 244
pattern 237                                                     ****
                  + GC GG   NA+ Y+ +N GI +E +YPY  +    C +N       + AK  
Sbjct:  174 ------NYGCGGGYMTNAFQYVQRNRGIDSEDAYPYVGQ-DESCMYNPTG----KAAKCR 222

Query:  245 NFTMIPK-NETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGILIVG 300
             +  IP+ NE  +   +   GP+++A DA    +QFY  GV +D  C+ ++++H +L VG
Sbjct:  223 GYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDENCSSDNVNHAVLAVG 282

Query:  301 YSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 347
            Y       +K   +WI+KNSWG  WG +GYI + R K N CG++N  S
Sbjct:  283 YG-----IQKGNKHWIIKNSWGESWGNKGYILMARNKNNACGIANLAS 325


>sp|P22895|P34_SOYBN P34 PROBABLE THIOL PROTEASE PRECURSOR
          Length = 379

 Score =  182 bits (458), Expect = 8e-46
 Identities = 110/322 (34%), Positives = 173/322 (53%), Gaps = 38/322 (11%)

Query:  40  YSHEEYLERFEIFKSNLGKIEELNLIAINHKA--DTKFGVNKFADLSSDEFKNYYLNNKE 97
            ++HEE  +R EIFK+N   I ++N    N K+    + G+NKFAD++  EF   YL   +
Sbjct:  56  HNHEEEAKRLEIFKNNSNYIRDMNA---NRKSPHSHRLGLNKFADITPQEFSKKYLQAPK 112

Query:  98  AIFTDDLPVAD--YLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNV 155
             + +  + +A+     +++    PP    ++DWR +G +T VK QG CG  W+FS TG +
Sbjct:  113 DV-SQQIKMANKKMKKEQYSCDHPP---ASWDWRKKGVITQVKYQGGCGRGWAFSATGAI 168

Query:  156 EGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTE 215
            E  H I+   LVSLSEQ LVDC  E           EG   G Q  ++ +++++GGI T+
Sbjct:  169 EAAHAIATGDLVSLSEQELVDCVEE----------SEGSYNGWQYQSFEWVLEHGGIATD 218

Query:  216 SSYPYTAETGTQCNFN----SANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAAD 271
pattern 237                          ****
              YPY A+ G +C  N       I   E   +S+ +   + E      I+   P++++ D
Sbjct:  219 DDYPYRAKEG-RCKANKIQDKVTIDGYETLIMSDESTESETEQAFLSAILEQ-PISVSID 276

Query:  272 AVEWQFYIGGVFDIP--CNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQG 329
            A ++  Y GG++D     +P  ++H +L+VGY + +      + YWI KNSWG DWGE G
Sbjct:  277 AKDFHLYTGGIYDGENCTSPYGINHFVLLVGYGSAD-----GVDYWIAKNSWGFDWGEDG 331

Query:  330 YIYLRRGK----NTCGVSNFVS 347
            YI+++R        CG++ F S
Sbjct:  332 YIWIQRNTGNLLGVCGMNYFAS 353


>sp|P49935|CATH_MOUSE CATHEPSIN H PRECURSOR (CATHEPSIN B3) (CATHEPSIN BA)
          Length = 333

 Score =  180 bits (451), Expect = 5e-45
 Identities = 115/332 (34%), Positives = 166/332 (49%), Gaps = 36/332 (10%)

Query:  25  EQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLS 84
            E+  F  +  +  K YS  EY  R ++F +N  KI+  N    NH    K  +N+F+D+S
Sbjct:  29  EKFHFKSWMKQHQKTYSSVEYNHRLQMFANNWRKIQAHN--QRNHTF--KMALNQFSDMS 84

Query:  85  SDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRG-AVTPVKNQGQC 143
              E K+ +L ++                 ++    P   ++ DWR +G  V+PVKNQG C
Sbjct:  85  FAEIKHKFLWSEPQN-------CSATKSNYLRGTGPYP-SSMDWRKKGNVVSPVKNQGAC 136

Query:  144 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 203
             SCW+FSTTG +E    I+  K++SL+EQ LVDC         +   + GC GGL   A+
Sbjct:  137 ASCWTFSTTGALESAVAIASGKMLSLAEQQLVDC--------AQAFNNHGCKGGLPSQAF 188

Query:  204 NYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKN-ETVMAGYIVS 262
pattern 237                                  ****
             YI+ N GI  E SYPY  +  + C FN      +  A + N   I  N E  M   +  
Sbjct:  189 EYILYNKGIMEEDSYPYIGK-DSSCRFNP----QKAVAFVKNVVNITLNDEAAMVEAVAL 243

Query:  263 TGPLAIAADAVE-WQFYIGGVFDIPC---NPNSLDHGILIVGYSAKNTIFRKNMPYWIVK 318
              P++ A +  E +  Y  GV+        P+ ++H +L VGY  +N +      YWIVK
Sbjct:  244 YNPVSFAFEVTEDFLMYKSGVYSSKSCHKTPDKVNHAVLAVGYGEQNGLL-----YWIVK 298

Query:  319 NSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 350
            NSWG+ WGE GY  + RGKN CG++   S  I
Sbjct:  299 NSWGSQWGENGYFLIERGKNMCGLAACASYPI 330


>sp|P55097|CATK_MOUSE CATHEPSIN K PRECURSOR
          Length = 329

 Score =  178 bits (447), Expect = 2e-44
 Identities = 117/352 (33%), Positives = 182/352 (51%), Gaps = 43/352 (12%)

Query:  9   LAVFTVFVSSRGIPPEEQ--SQFLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLI 65
            L V  + + S  + PEE   +Q+  ++    K+Y+ + + + R  I++ NL +I   NL 
Sbjct:  4   LKVLLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLE 63

Query:  66  AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDD-----EFINSIPP 120
            A       +  +N   D++S+E        +        P   Y +D     E+   +P 
Sbjct:  64  ASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIP------PSRSYSNDTLYTPEWEGRVPD 117

Query:  121 EEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 180
                + D+R +G VTPVKNQGQCGSCW+FS+ G +EGQ      KL++LS QNLVDC  E
Sbjct:  118 ----SIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE 173

Query:  181 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQ 240
pattern 237                                                         ****
                      + GC GG    A+ Y+ +NGGI +E ++PY  +    C +N+      + 
Sbjct:  174 ----------NYGCGGGYMTTAFQYVQQNGGIDSEDAFPYVGQ-DESCMYNAT----AKA 218

Query:  241 AKISNFTMIP-KNETVMAGYIVSTGPLAIAADA--VEWQFYIGGV-FDIPCNPNSLDHGI 296
            AK   +  IP  NE  +   +   GP++++ DA    +QFY  GV +D  C+ ++++H +
Sbjct:  219 AKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAV 278

Query:  297 LIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 347
            L+VGY       +K   +WI+KNSWG  WG +GY  L R K N CG++N  S
Sbjct:  279 LVVGYGT-----QKGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMAS 325


>sp|P56202|CATW_HUMAN CATHEPSIN W PRECURSOR (LYMPHOPAIN)
          Length = 376

 Score =  177 bits (445), Expect = 3e-44
 Identities = 112/351 (31%), Positives = 171/351 (47%), Gaps = 47/351 (13%)

Query:  22  PPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
            P E +  F  FQ +FN+ Y S EE+  R +IF  NL + + L    +      +FGV  F
Sbjct:  35  PLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLG---TAEFGVTPF 91

Query:  81  ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAF--DWR-TRGAVTPV 137
            +DL+ +EF   Y   + A     +          I S  PEE   F  DWR   GA++P+
Sbjct:  92  SDLTEEEFGQLYGYRRAAGGVPSM-------GREIRSEEPEESVPFSCDWRKVAGAISPI 144

Query:  138 KNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGG 197
            K+Q  C  CW+ +  GN+E    IS    V +S   L+DC            C +GC+GG
Sbjct:  145 KDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVHELLDCGR----------CGDGCHGG 194

Query:  198 LQPNAYNYIIKNGGIQTESSYPYTAETGT-QCNFNSANIGPEEQAKISNFTMIPKNETVM 256
pattern 237                                         ****
               +A+  ++ N G+ +E  YP+  +    +C+        ++ A I +F M+  NE  +
Sbjct:  195 FVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKY----QKVAWIQDFIMLQNNEHRI 250

Query:  257 AGYIVSTGPLAIAADAVEWQFYIGGVFDIP---CNPNSLDHGILIVGYSA--------KN 305
            A Y+ + GP+ +  +    Q Y  GV       C+P  +DH +L+VG+ +          
Sbjct:  251 AQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAE 310

Query:  306 TIFRKNMP-------YWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 349
            T+  ++ P       YWI+KNSWGA WGE+GY  L RG NTCG++ F  T+
Sbjct:  311 TVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTA 361


>sp|P56203|CATW_MOUSE CATHEPSIN W PRECURSOR (LYMPHOPAIN)
          Length = 371

 Score =  176 bits (442), Expect = 6e-44
 Identities = 110/346 (31%), Positives = 166/346 (47%), Gaps = 40/346 (11%)

Query:  22  PPEEQSQFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKF 80
            P E +  F  FQ +FN+ Y +  EY  R  IF  NL + + L    +      +FG   F
Sbjct:  33  PLELKEVFKLFQIRFNRSYWNPAEYTRRLSIFAHNLAQAQRLQQEDLG---TAEFGETPF 89

Query:  81  ADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWR-TRGAVTPVKN 139
            +DL+ +EF   Y   +    T ++       + +  S+P       DWR  +  ++ VKN
Sbjct:  90  SDLTEEEFGQLYGQERSPERTPNM-TKKVESNTWGESVP----RTCDWRKAKNIISSVKN 144

Query:  140 QGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQ 199
            QG C  CW+ +   N++    I   + V +S Q L+DC          E C  GCNGG  
Sbjct:  145 QGSCKCCWAMAAADNIQALWRIKHQQFVDVSVQELLDC----------ERCGNGCNGGFV 194

Query:  200 PNAYNYIIKNGGIQTESSYPYTAETGT-QCNFNSANIGPEEQAKISNFTMIPKNETVMAG 258
pattern 237                                       ****
             +AY  ++ N G+ +E  YP+  +    +C         ++ A I +FTM+  NE  +A 
Sbjct:  195 WDAYLTVLNNSGLASEKDYPFQGDRKPHRCLAKKY----KKVAWIQDFTMLSNNEQAIAH 250

Query:  259 YIVSTGPLAIAADAVEWQFYIGGVFDIP---CNPNSLDHGILIVGYSAKN------TIF- 308
            Y+   GP+ +  +    Q Y  GV       C+P  +DH +L+VG+  K       T+  
Sbjct:  251 YLAVHGPITVTINMKLLQHYQKGVIKATPSSCDPRQVDHSVLLVGFGKKKEGMQTGTVLS 310

Query:  309 -----RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTS 349
                 R + PYWI+KNSWGA WGE+GY  L RG NTCGV+ +  T+
Sbjct:  311 HSRKRRHSSPYWILKNSWGAHWGEKGYFRLYRGNNTCGVTKYPFTA 356


>sp|P43234|CATO_HUMAN CATHEPSIN O PRECURSOR
          Length = 321

 Score =  173 bits (435), Expect = 4e-43
 Identities = 100/304 (32%), Positives = 152/304 (49%), Gaps = 30/304 (9%)

Query:  52  FKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLD 111
            F+ +L +   LN +  +  +   +G+N+F+ L  +EFK  YL +K + F           
Sbjct:  44  FRESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPR-------YS 96

Query:  112 DEFINSIPPEE-QTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLS 170
             E   SIP       FDWR +  VT V+NQ  CG CW+FS  G VE  + I    L  LS
Sbjct:  97  AEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLS 156

Query:  171 EQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK-NGGIQTESSYPYTAETGTQCN 229
             Q ++DC +           + GCNGG   NA N++ K    +  +S YP+ A+ G  C+
Sbjct:  157 VQQVIDCSYN----------NYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGL-CH 205

Query:  230 FNSANIGPEEQAKISNFTM--IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPC 287
pattern 237        ****
            + S   G      I  ++       E  MA  +++ GPL +  DAV WQ Y+GG+    C
Sbjct:  206 YFS---GSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHC 262

Query:  288 NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVS 347
            +    +H +LI G+         + PYWIV+NSWG+ WG  GY +++ G N CG+++ VS
Sbjct:  263 SSGEANHAVLITGFDKTG-----STPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVS 317

Query:  348 TSII 351
            +  +
Sbjct:  318 SIFV 321


>sp|P00784|PAPA_CARPA PAPAIN PRECURSOR (PAPAYA PROTEINASE I) (PPI)
          Length = 345

 Score =  173 bits (433), Expect = 7e-43
 Identities = 119/322 (36%), Positives = 163/322 (49%), Gaps = 43/322 (13%)

Query:  35  KFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKFADLSSDEFKNY 91
            K NK Y + +E + RFEIFK NL  I+E N      K +  +  G+N FAD+S+DEFK  
Sbjct:  54  KHNKIYKNIDEKIYRFEIFKDNLKYIDETN------KKNNSYWLGLNVFADMSNDEFKEK 107

Query:  92  YLNNKEAIFTD-DLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFS 150
            Y  +    +T  +L   + L+D  +N   PE     DWR +GAVTPVKNQG CGSCW+FS
Sbjct:  108 YTGSIAGNYTTTELSYEEVLNDGDVNI--PEY---VDWRQKGAVTPVKNQGSCGSCWAFS 162

Query:  151 TTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNG 210
                +EG   I    L   SEQ L+DCD              GCNGG   +A   ++   
Sbjct:  163 AVVTIEGIIKIRTGNLNEYSEQELLDCDRR----------SYGCNGGYPWSALQ-LVAQY 211

Query:  211 GIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAA 270
pattern 237                           ****
            GI   ++YPY    G Q    S   GP          + P NE  +  Y ++  P+++  
Sbjct:  212 GIHYRNTYPY---EGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALL-YSIANQPVSVVL 267

Query:  271 DAV--EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQ 328
            +A   ++Q Y GG+F  PC  N +DH +  VGY            Y ++KNSWG  WGE 
Sbjct:  268 EAAGKDFQLYRGGIFVGPCG-NKVDHAVAAVGYGPN---------YILIKNSWGTGWGEN 317

Query:  329 GYIYLRRGK-NTCGVSNFVSTS 349
            GYI ++RG  N+ GV    ++S
Sbjct:  318 GYIRIKRGTGNSYGVCGLYTSS 339


>sp|P25774|CATS_HUMAN CATHEPSIN S PRECURSOR
          Length = 331

 Score =  171 bits (428), Expect = 3e-42
 Identities = 116/351 (33%), Positives = 175/351 (49%), Gaps = 35/351 (9%)

Query:  5   LLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYS--HEEYLERFEIFKSNLGKIEEL 62
            L+ VL V +  V+     P     +  ++  + K+Y   +EE + R  I++ NL  +   
Sbjct:  4   LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRL-IWEKNLKFVMLH 62

Query:  63  NLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEE 122
            NL           G+N   D++S+E  +          T  L V             P  
Sbjct:  63  NLEHSMGMHSYDLGMNHLGDMTSEEVMS---------LTSSLRVPSQWQRNITYKSNPNR 113

Query:  123 --QTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHE 180
                + DWR +G VT VK QG CG+CW+FS  G +E Q  +   KLV+LS QNLVDC   
Sbjct:  114 ILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDC--- 170

Query:  181 CMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQ 240
pattern 237                                                         ****
                  E+  ++GCNGG    A+ YII N GI +++SYPY A    +C ++S        
Sbjct:  171 ----STEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKA-MDQKCQYDS----KYRA 221

Query:  241 AKISNFTMIP-KNETVMAGYIVSTGPLAIAADAVEWQFYI--GGVFDIPCNPNSLDHGIL 297
            A  S +T +P   E V+   + + GP+++  DA    F++   GV+  P    +++HG+L
Sbjct:  222 ATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVL 281

Query:  298 IVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 347
            +VGY   N        YW+VKNSWG ++GE+GYI + R K N CG+++F S
Sbjct:  282 VVGYGDLN-----GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPS 327


>sp||CATL_CHICK_1 [Segment 1 of 2] CATHEPSIN L
          Length = 176

 Score =  167 bits (420), Expect = 2e-41
 Identities = 87/179 (48%), Positives = 115/179 (63%), Gaps = 16/179 (8%)

Query:  127 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEG 186
            DWR +G VTPVK+QGQCGSCW+FSTTG +EGQHF ++ KLVSLSEQNLVDC       EG
Sbjct:  6   DWREKGYVTPVKDQGQCGSCWAFSTTGALEGQHFRTKGKLVSLSEQNLVDCSRP----EG 61

Query:  187 EEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNF 246
pattern 237                                                   ****
                ++GCNGGL   A+ Y+  NGGI +E SYPYTA+    C + +        A  + F
Sbjct:  62  ----NQGCNGGLMDQAFQYVQDNGGIDSEESYPYTAKDDEDCRYKA----EYNAANDTGF 113

Query:  247 TMIPK-NETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIP-CNPNSLDHGILIVGY 301
              IP+ +E  +   + S GP+++A DA    +QFY  G++  P C+   LDHG+L+VGY
Sbjct:  114 VDIPQGHERALMKAVASVGPVSVAIDAGHSSFQFYQSGIYYEPDCSSEDLDHGVLVVGY 172


>sp|P25326|CATS_BOVIN CATHEPSIN S
          Length = 217

 Score =  165 bits (413), Expect = 1e-40
 Identities = 90/227 (39%), Positives = 129/227 (56%), Gaps = 21/227 (9%)

Query:  125 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 184
            + DWR +G VT VK QG CGSCW+FS  G +E Q  +   KLVSLS QNLVDC       
Sbjct:  4   SMDWREKGCVTEVKYQGACGSCWAFSAVGALEAQVKLKTGKLVSLSAQNLVDC------- 56

Query:  185 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKIS 244
pattern 237                                                     ****
               +  ++GCNGG    A+ YII N GI +E+SYPY A  G +C ++  N      A  S
Sbjct:  57  STAKYGNKGCNGGFMTEAFQYIIDNNGIDSEASYPYKAMDG-KCQYDVKN----RAATCS 111

Query:  245 NFTMIP-KNETVMAGYIVSTGPLAIAADAVEWQFYI--GGVFDIPCNPNSLDHGILIVGY 301
             +  +P  +E  +   + + GP+++  DA    F++   GV+  P    +++HG+L+VGY
Sbjct:  112 RYIELPFGSEEALKEAVANKGPVSVGIDASHSSFFLYKTGVYYDPSCTQNVNHGVLVVGY 171

Query:  302 SAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK-NTCGVSNFVS 347
               +        YW+VKNSWG  +G+QGYI + R   N CG++N+ S
Sbjct:  172 GNLD-----GKDYWLVKNSWGLHFGDQGYIRMARNSGNHCGIANYPS 213


>sp|P80884|ANAN_ANACO ANANAIN
          Length = 216

 Score =  161 bits (403), Expect = 2e-39
 Identities = 93/224 (41%), Positives = 123/224 (54%), Gaps = 26/224 (11%)

Query:  125 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 184
            + DWR  GAVT VKNQG+CGSCW+F++   VE  + I +  LVSLSEQ ++DC       
Sbjct:  4   SIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDC------- 56

Query:  185 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKIS 244
pattern 237                                                     ****
                A   GC GG    AY++II N G+ + + YPY A  GT C  N    G    A I+
Sbjct:  57  ----AVSYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGT-CKTN----GVPNSAYIT 107

Query:  245 NFTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSA 303
             +T + +N      Y VS  P+A A DA   +Q Y  GVF  PC    L+H I+I+GY  
Sbjct:  108 RYTYVQRNNERNMMYAVSNQPIAAALDASGNFQHYKRGVFTGPCG-TRLNHAIVIIGYGQ 166

Query:  304 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT----CGVS 343
             +        +WIV+NSWGA WGE GYI L R  ++    CG++
Sbjct:  167 DSA----GKKFWIVRNSWGAGWGEGGYIRLARDVSSSFGICGIA 206


>sp|Q02765|CATS_RAT CATHEPSIN S PRECURSOR
          Length = 330

 Score =  158 bits (396), Expect = 1e-38
 Identities = 89/226 (39%), Positives = 128/226 (56%), Gaps = 22/226 (9%)

Query:  127 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEG 186
            DWR +G VT VK QG CGSCW+FS  G +EGQ  +   KLVSLS QNLVDC  E      
Sbjct:  118 DWREKGCVTNVKYQGSCGSCWAFSAEGALEGQLKLKTGKLVSLSAQNLVDCSTE------ 171

Query:  187 EEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNF 246
pattern 237                                                   ****
            E+  ++GC GG    A+ YII +  I +E+SYPY A    +C ++  N      A  S +
Sbjct:  172 EKYGNKGCGGGFMTEAFQYII-DTSIDSEASYPYKA-MDEKCLYDPKN----RAATCSRY 225

Query:  247 TMIP-KNETVMAGYIVSTGPLAIAADAV---EWQFYIGGVFDIPCNPNSLDHGILIVGYS 302
              +P  +E  +   + + GP+++  D      +  Y  GV+D P    +++HG+L+VGY 
Sbjct:  226 IELPFGDEEALKEAVATKGPVSVGIDDASHSSFFLYQSGVYDDPSCTENMNHGVLVVGYG 285

Query:  303 AKNTIFRKNMPYWIVKNSWGADWGEQGYIYL-RRGKNTCGVSNFVS 347
              +        YW+VKNSWG  +G+QGYI + R  KN CG++++ S
Sbjct:  286 TLD-----GKDYWLVKNSWGLHFGDQGYIRMARNNKNHCGIASYCS 326


>sp|P20721|CYSL_LYCES LOW-TEMPERATURE-INDUCED CYSTEINE PROTEINASE PRECURSOR
          Length = 346

 Score =  158 bits (395), Expect = 2e-38
 Identities = 87/238 (36%), Positives = 130/238 (54%), Gaps = 25/238 (10%)

Query:  112 DEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSE 171
            D ++  +      + DWR +G +  VK+QG CGSCW+FS    +E  + I    L+SLSE
Sbjct:  8   DRYLPKVGDSLPESIDWREKGVLVGVKDQGSCGSCWAFSAVAAMESINAIVTGNLISLSE 67

Query:  172 QNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFN 231
            Q LVDCD          + +EGC+GGL   A+ ++IKNGGI TE  YPY    G  C+  
Sbjct:  68  QELVDCD---------RSYNEGCDGGLMDYAFEFVIKNGGIDTEEDYPYKERNGV-CDQY 117

Query:  232 SANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA--VEWQFYIGGVFDIPCNP 289
pattern 237      ****
              N    +  KI ++  +P N        V+  P++IA +A   ++Q Y  G+F   C  
Sbjct:  118 RKN---AKVVKIDSYEDVPVNNEKALQKAVAHQPVSIALEAGGRDFQHYKSGIFTGKCG- 173

Query:  290 NSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNT----CGVS 343
             ++DHG++I GY  +N      M YWIV+NSWGA+  E GY+ ++R  ++    CG++
Sbjct:  174 TAVDHGVVIAGYGTEN-----GMDYWIVRNSWGANCRENGYLRVQRNVSSSSGLCGLA 226


>sp|P36184|ACP1_ENTHI CYSTEINE PROTEINASE ACP1 PRECURSOR
          Length = 308

 Score =  152 bits (379), Expect = 1e-36
 Identities = 105/320 (32%), Positives = 151/320 (46%), Gaps = 48/320 (15%)

Query:  29  FLEFQDKFNKKYSHE-EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDE 87
            F ++    NK +++  EYL RF +F  N   +E          A+    +N FAD++ +E
Sbjct:  18  FKQWAATHNKVFANRAEYLYRFAVFLDNKKFVE----------ANANTELNVFADMTHEE 67

Query:  88  FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCW 147
            F   +L       T ++P         + + P     + DWR+   + P K+QGQCGSCW
Sbjct:  68  FIQTHLG-----MTYEVPETTSNVKAAVKAAPE----SVDWRS--IMNPAKDQGQCGSCW 116

Query:  148 SFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYII 207
            +F TT  +EG+      KL S SEQ LVDCD          A D GC GG   N+  +I 
Sbjct:  117 TFCTTAVLEGRVNKDLGKLYSFSEQQLVDCD----------ASDNGCEGGHPSNSLKFIQ 166

Query:  208 KNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLA 267
pattern 237                              ****
            +N G+  ES YPY A  GT C     N+     ++     +   +ET +   I   GP+A
Sbjct:  167 ENNGLGLESDYPYKAVAGT-CK-KVKNVATVTGSR----RVTDGSETGLQTIIAENGPVA 220

Query:  268 IAADA--VEWQFYIGGVF--DIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGA 323
            +  DA    +Q Y  G    D  C    ++H +  VGY + +     N  YWI++NSWG 
Sbjct:  221 VGMDASRPSFQLYKKGTIYSDTKCRSRMMNHCVTAVGYGSNS-----NGKYWIIRNSWGT 275

Query:  324 DWGEQGYIYLRR-GKNTCGV 342
             WG+ GY  L R   N CG+
Sbjct:  276 SWGDAGYFLLARDSNNMCGI 295


>sp|Q01957|CPP1_ENTHI CYSTEINE PROTEINASE 1 PRECURSOR
          Length = 315

 Score =  150 bits (375), Expect = 4e-36
 Identities = 103/317 (32%), Positives = 163/317 (50%), Gaps = 47/317 (14%)

Query:  37  NKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADT-KFGVN-KFADLSSDEFKNYYLN 94
            NK ++  E L R  IF  N        ++A N++ +T K  V+  FA ++++E+ +    
Sbjct:  24  NKHFTAVESLRRRAIFNMNA------RIVAENNRKETFKLSVDGPFAAMTNEEYNSLLKL 77

Query:  95  NKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGN 154
             +      ++         ++N   P+   A DWR +G VTP+++QG CGSC++F +   
Sbjct:  78  KRSGEEKGEV--------RYLNIQAPK---AVDWRKKGKVTPIRDQGNCGSCYTFGSIAA 126

Query:  155 VEGQHFISQ---NKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGG 211
            +EG+  I +   ++ + LSE+++V C  E    +G    + GCNGGL  N YNYI++N G
Sbjct:  127 LEGRLLIEKGGDSETLDLSEEHMVQCTRE----DG----NNGCNGGLGSNVYNYIMEN-G 177

Query:  212 IQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAAD 271
pattern 237                          ****
            I  ES YPYT    T           +  AKI ++  + +N  V     +S G + ++ D
Sbjct:  178 IAKESDYPYTGSDST------CRSDVKAFAKIKSYNRVARNNEVELKAAISQGLVDVSID 231

Query:  272 A--VEWQFYIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 326
            A  V++Q Y  G + D  C  N  +L+H +  VGY   +         WIV+NSWG  WG
Sbjct:  232 ASSVQFQLYKSGAYTDTQCKNNYFALNHEVCAVGYGVVD-----GKECWIVRNSWGTGWG 286

Query:  327 EQGYIYLRRGKNTCGVS 343
            E+GYI +    NTCGV+
Sbjct:  287 EKGYINMVIEGNTCGVA 303


>sp|O17473|CATL_BRUPA CATHEPSIN L-LIKE PRECURSOR
          Length = 395

 Score =  150 bits (374), Expect = 6e-36
 Identities = 101/331 (30%), Positives = 157/331 (46%), Gaps = 29/331 (8%)

Query:  26  QSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
            ++++ ++     K Y  +E   R  IF+SN    E +N             +N  ADL+ 
Sbjct:  88  ETEWKDYVTALGKHYDQKENNFRMAIFESNELMTERINKKYEQGLVSYTTALNDLADLTD 147

Query:  86  DEF--KNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQC 143
            +EF  +N      +         +++   +    +P +     DWRT+GAVTPV+NQG+C
Sbjct:  148 EEFMVRNGLRLPNQTDLRGKRQTSEFYRYDKSERLPDQ----VDWRTKGAVTPVRNQGEC 203

Query:  144 GSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 203
            GSC++F+T   +E  H     +L+ LS QN+VDC             + GC+GG  P A+
Sbjct:  204 GSCYAFATAAALEAYHKQMTGRLLDLSPQNIVDCT--------RNLGNNGCSGGYMPTAF 255

Query:  204 NYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMI-PKNETVMAGYIVS 262
pattern 237                                  ****
             Y  +  GI  ES YPY   T  +C +  +     +    + F  I P +E  +   +  
Sbjct:  256 QYASRY-GIAMESRYPYVG-TEQRCRWQQSIAVVTD----NGFNEIQPGDELALKHAVAK 309

Query:  263 TGP--LAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNS 320
             GP  + I+     ++FY  GV+    N    DH +L VGY    +       YWIVKNS
Sbjct:  310 RGPVVVGISGSKRSFRFYKDGVYS-EGNCGRPDHAVLAVGYGTHPSY----GDYWIVKNS 364

Query:  321 WGADWGEQGYIYLRRGK-NTCGVSNFVSTSI 350
            WG DWG+ GY+Y+ R + N C +++  S  I
Sbjct:  365 WGTDWGKDGYVYMARNRGNMCHIASAASFPI 395


>sp|P46102|CYSP_PLAVN CYSTEINE PROTEINASE PRECURSOR
          Length = 506

 Score =  150 bits (374), Expect = 6e-36
 Identities = 116/363 (31%), Positives = 180/363 (48%), Gaps = 64/363 (17%)

Query:  27  SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
            S+F ++  + NKKY + +E L+RFE FK    K ++ N +   +       VN+++D S 
Sbjct:  160 SKFFKYMKENNKKYENMDEQLQRFENFKIRYMKTQKHNEMVGKNGLTYVQKVNQYSDFSK 219

Query:  86  DEFKNYYLNNKEAIFTDDL------PVADYLDDEFINSIPPEEQT---AFDWRTRGAVTP 136
            +EF NY+   K      DL      P+  +L +  + S+  + +    + D+R++    P
Sbjct:  220 EEFDNYF--KKLLSVPMDLKSKYIVPLKKHLANTNLISVDNKSKDFPDSRDYRSKFNFLP 277

Query:  137 VKNQGQCGSCWSFSTTGNVEGQHFISQNKL-VSLSEQNLVDCDHECMEYEGEEACDEGCN 195
             K+QG CGSCW+F+  GN E  +  +++++ +S SEQ +VDC  E          + GC+
Sbjct:  278 PKDQGNCGSCWAFAAIGNFEYLYVHTRHEMPISFSEQQMVDCSTE----------NYGCD 327

Query:  196 GGLQPNAYNYIIKNGGIQTESSYPYTAETGTQC-NFNSANIGPEEQAKISNFTMIPKNET 254
pattern 237                                           ****
            GG    A+ Y+I NG +     YPY       C N+  + +G     ++     +  NE 
Sbjct:  328 GGNPFYAFLYMINNG-VCLGDEYPYKGHEDFFCLNYRCSLLG-----RVHFIGDVKPNEL 381

Query:  255 VMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSA---------- 303
            +MA   V  GP+ IA  A E +  Y GGVFD  CNP  L+H +L+VGY            
Sbjct:  382 IMALNYV--GPVTIAVGASEDFVLYSGGVFDGECNPE-LNHSVLLVGYGQVKKSLAFEDS 438

Query:  304 -----KNTI--FRKNMP---------YWIVKNSWGADWGEQGYIYLRRGK----NTCGVS 343
                  N I  +++N+          YWIV+NSWG +WGE GYI ++R K      CGV 
Sbjct:  439 HSNVDSNLIKKYKENIKGDDDDDIIYYWIVRNSWGPNWGEGGYIRIKRNKAGDDGFCGVG 498

Query:  344 NFV 346
            + V
Sbjct:  499 SDV 501


>sp|Q06964|CPP3_ENTHI CYSTEINE PROTEINASE 3 PRECURSOR (CYSTEINE PROTEINASE ACP3)
          Length = 308

 Score =  149 bits (372), Expect = 9e-36
 Identities = 103/316 (32%), Positives = 159/316 (49%), Gaps = 45/316 (14%)

Query:  37  NKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN-KFADLSSDEFKNYYLNN 95
            NK ++  E L R  IF  N   + E N      K   K  V+  FA ++++E++   L +
Sbjct:  17  NKHFTAVEALRRRAIFNMNARFVAEFN-----KKGSFKLSVDGPFAAMTNEEYRTL-LKS 70

Query:  96  KEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNV 155
            K  +  +           ++N   PE   + DWR +G VTP+++Q QCGSC++F +   +
Sbjct:  71  KRTVEENGKVT-------YLNIQAPE---SVDWRAQGKVTPIRDQAQCGSCYTFGSLAAL 120

Query:  156 EGQHFISQN---KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGI 212
            EG+  I +      + LSE++LV C          +  + GCNGGL  N Y+YII+N G+
Sbjct:  121 EGRLLIEKGGNANTLDLSEEHLVQCT--------RDNGNNGCNGGLGSNVYDYIIQN-GV 171

Query:  213 QTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADA 272
pattern 237                         ****
              ES YPYT  T + C  N      +  AKI+ +  +P+N        +S G + ++ DA
Sbjct:  172 AKESDYPYTG-TDSTCKTN-----VKAFAKITGYNKVPRNNEAELKAALSQGLVDVSIDA 225

Query:  273 --VEWQFYIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGE 327
               ++Q Y  G + D  C  N  +L+H +  VGY   +         WIV+NSWG  WG+
Sbjct:  226 SSAKFQLYKSGAYSDTKCKNNFFALNHEVCAVGYGVVD-----GKECWIVRNSWGTGWGD 280

Query:  328 QGYIYLRRGKNTCGVS 343
            +GYI +    NTCGV+
Sbjct:  281 KGYINMVIEGNTCGVA 296


>sp|Q01958|CPP2_ENTHI CYSTEINE PROTEINASE 2 PRECURSOR
          Length = 315

 Score =  149 bits (372), Expect = 9e-36
 Identities = 102/324 (31%), Positives = 161/324 (49%), Gaps = 45/324 (13%)

Query:  29  FLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN-KFADLSSDE 87
            F  +  K NK ++  E L R  IF  N   ++  N I        K  V+  FA ++++E
Sbjct:  16  FNTWASKNNKHFTAIEKLRRRAIFNMNAKFVDSFNKIG-----SFKLSVDGPFAAMTNEE 70

Query:  88  FKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCW 147
            ++    + +    T++     YL+ +   S+        DWR  G VTP+++Q QCGSC+
Sbjct:  71  YRTLLKSKRT---TEENGQVKYLNIQAPESV--------DWRKEGKVTPIRDQAQCGSCY 119

Query:  148 SFSTTGNVEGQHFISQN---KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYN 204
            +F +   +EG+  I +      + LSE+++V C          +  + GCNGGL  N Y+
Sbjct:  120 TFGSLAALEGRLLIEKGGDANTLDLSEEHMVQCT--------RDNGNNGCNGGLGSNVYD 171

Query:  205 YIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTG 264
pattern 237                                 ****
            YII++ G+  ES YPYT    T C  N  +      AKI+ +T +P+N        +S G
Sbjct:  172 YIIEH-GVAKESDYPYTGSDST-CKTNVKSF-----AKITGYTKVPRNNEAELKAALSQG 224

Query:  265 PLAIAADA--VEWQFYIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMPYWIVKN 319
             + ++ DA   ++Q Y  G + D  C  N  +L+H +  VGY   +         WIV+N
Sbjct:  225 LVDVSIDASSAKFQLYKSGAYTDTKCKNNYFALNHEVCAVGYGVVD-----GKECWIVRN 279

Query:  320 SWGADWGEQGYIYLRRGKNTCGVS 343
            SWG  WG++GYI +    NTCGV+
Sbjct:  280 SWGTGWGDKGYINMVIEGNTCGVA 303


>sp|P36185|ACP2_ENTHI CYSTEINE PROTEINASE ACP2 PRECURSOR
          Length = 310

 Score =  145 bits (363), Expect = 1e-34
 Identities = 102/330 (30%), Positives = 160/330 (47%), Gaps = 40/330 (12%)

Query:  20  GIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVN- 78
            GI       F  +  K NK ++  E L R  IF  N   ++  N I        K  V+ 
Sbjct:  3   GIRIASAIDFNTWASKNNKHFTAIEKLRRRAIFNMNAKFVDSFNKIG-----SFKLSVDG 57

Query:  79  KFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVK 138
             FA ++++E++    + +    T++     YL+ +   S+        DWR  G VTP++
Sbjct:  58  PFAAMTNEEYRTLLKSKRT---TEENGQVKYLNIQAPESV--------DWRKEGKVTPLR 106

Query:  139 NQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGL 198
            +Q QCGSC++F +   +EG+  I +       + N +D   E M+   +   + GCNGGL
Sbjct:  107 DQAQCGSCYTFGSLAALEGRLLIEKG-----GDANTLDLSEEHMQCTRDNG-NNGCNGGL 160

Query:  199 QPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAG 258
pattern 237                                       ****
              N Y+YII++G +  ES YPYT    T C  N  +       KI+ +T +P+N      
Sbjct:  161 GSNVYDYIIEHG-VAKESDYPYTGSDST-CKTNVKSF-----RKITGYTKVPRNNEAELK 213

Query:  259 YIVSTGPLAIAAD--AVEWQFYIGGVF-DIPCNPN--SLDHGILIVGYSAKNTIFRKNMP 313
              +S G L ++ D  + ++Q Y  G + D  C  N  +L+H +  VGY   +        
Sbjct:  214 AALSQGLLDVSIDVSSAKFQLYKSGAYTDTKCKNNYFALNHEVCAVGYGVVD-----GKE 268

Query:  314 YWIVKNSWGADWGEQGYIYLRRGKNTCGVS 343
             WIV+NSWG  WG++GYI +    NTCGV+
Sbjct:  269 CWIVRNSWGTSWGDKGYINMVIEGNTCGVA 298


>sp|P25781|CYSP_THEAN CYSTEINE PROTEINASE PRECURSOR
          Length = 441

 Score =  145 bits (362), Expect = 1e-34
 Identities = 107/345 (31%), Positives = 165/345 (47%), Gaps = 58/345 (16%)

Query:  28  QFLEFQDKFNKKY-SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGV--NKFADLS 84
            +F  F +K+ K + S ++ ++RF  F+ N   ++        HK    + +  NKF+DLS
Sbjct:  119 EFDAFVEKYKKVHRSFDQRVQRFLTFRKNYHIVK-------THKPTEPYSLDLNKFSDLS 171

Query:  85  SDEFKNYY--------------------LNNKEAIFTDDLPVADYLDDEFINSIPPEEQT 124
             +EFK  Y                    +++K  I+   L  A  +++    S+   E  
Sbjct:  172 DEEFKALYPVITPPKTYTSLSKHLEFKKMSHKNPIYISKLKKAKGIEEIKDLSLITGEN- 230

Query:  125 AFDWRTRGAVTPVKNQGQ-CGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECME 183
              +W    AV+P K+QG  CGSCW+FS+  +VE  + + +NK   LSEQ LV+CD   M 
Sbjct:  231 -LNWARTDAVSPTKDQGDHCGSCWAFSSIASVESLYRLYKNKSYFLSEQELVNCDKSSM- 288

Query:  184 YEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKI 243
pattern 237                                                      ****
                     GC GGL   A  Y I + G+  ES  PYT    + C  +  N     +  I
Sbjct:  289 ---------GCAGGLPITALEY-IHSKGVSFESEVPYTGIV-SPCKPSIKN-----KVFI 332

Query:  244 SNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSA 303
             + +++  N+ V    ++S   + IA    E + Y GG+F   C    L+H +L+VG   
Sbjct:  333 DSISILKGNDVVNKSLVISPTVVGIAV-TKELKLYSGGIFTGKCG-GELNHAVLLVGEGV 390

Query:  304 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR---GKNTCGVSNF 345
             +      M YWI+KNSWG DWGE G++ L+R   G + CG+  F
Sbjct:  391 DH---ETGMRYWIIKNSWGEDWGENGFLRLQRTKKGLDKCGILTF 432


>sp|P22497|CYSP_THEPA CYSTEINE PROTEINASE PRECURSOR
          Length = 439

 Score =  143 bits (357), Expect = 5e-34
 Identities = 105/351 (29%), Positives = 163/351 (45%), Gaps = 72/351 (20%)

Query:  24  EEQSQFLEFQDKFNKKYS-HEEYLERFEIFKSNLGKIEELNLIAINHKADTKF--GVNKF 80
            E   +F EF  K+N++++  +E L R   F+SN  +++E        K D  +  G+N+F
Sbjct:  119 EVYREFEEFNSKYNRRHATQQERLNRLVTFRSNYLEVKE-------QKGDEPYVKGINRF 171

Query:  81  ADLSSDEF--------------------------KNYYLNNKEAIFTDDLPVADYLDDEF 114
            +DL+  EF                          K Y  N K+A+ TD+        D  
Sbjct:  172 SDLTEREFYKLFPVMKPPKATYSNGYYLLSHMANKTYLKNLKKALNTDE--------DVD 223

Query:  115 INSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNL 174
            +  +  E     DWR   +VT VK+Q  CG CW+FST G+VEG +    +K   LS Q L
Sbjct:  224 LAKLTGEN---LDWRRSSSVTSVKDQSNCGGCWAFSTVGSVEGYYMSHFDKSYELSVQEL 280

Query:  175 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSAN 234
            +DCD          +   GC GGL  +AY Y+ K  G+ +    P+  +   +C+   A 
Sbjct:  281 LDCD----------SFSNGCQGGLLESAYEYVRKY-GLVSAKDLPF-VDKARRCSVPKA- 327

Query:  235 IGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDH 294
pattern 237   ****
                ++  + ++ +  K + VM   + S+      + + E   Y  GVF   C   SL+H
Sbjct:  328 ----KKVSVPSYHVF-KGKEVMTRSLTSSPCSVYLSVSPELAKYKSGVFTGECG-KSLNH 381

Query:  295 GILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR---GKNTCGV 342
             +++VG        ++   YW+V+NSWG DWGE GY+ L R   G + CGV
Sbjct:  382 AVVLVGEGYDEVTKKR---YWVVQNSWGTDWGENGYMRLERTNMGTDKCGV 429


>sp|P25805|CYSP_PLAFA THROPHOZOITE CYSTEINE PROTEINASE PRECURSOR (TCP)
          Length = 569

 Score =  141 bits (351), Expect = 3e-33
 Identities = 107/367 (29%), Positives = 169/367 (45%), Gaps = 62/367 (16%)

Query:  27  SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
            S+F +F  + NK Y + +E + +FEIFK N   I+  N   +N  A  K  VN+F+D S 
Sbjct:  223 SKFFKFMKEHNKVYKNIDEQMRKFEIFKINYISIKNHN--KLNKNAMYKKKVNQFSDYSE 280

Query:  86  DEFKNYYLN----NKEAIFTDDLPVADYLDD-----EFINSIPPEEQTAF-------DWR 129
            +E K Y+          I     P  ++L D     EF  +    E+  F       D+R
Sbjct:  281 EELKEYFKTLLHVPNHMIEKYSKPFENHLKDNILISEFYTNGKRNEKDIFSKVPEILDYR 340

Query:  130 TRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEA 189
             +G V   K+QG CGSCW+F++ GN+E         ++S SEQ +VDC  +         
Sbjct:  341 EKGIVHEPKDQGLCGSCWAFASVGNIESVFAKKNKNILSFSEQEVVDCSKD--------- 391

Query:  190 CDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMI 249
pattern 237                                                ****
             + GC+GG    ++ Y+++N  +     Y Y A+    C     N   + +  +S+   +
Sbjct:  392 -NFGCDGGHPFYSFLYVLQN-ELCLGDEYKYKAKDDMFC----LNYRCKRKVSLSSIGAV 445

Query:  250 PKNETVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGY------- 301
             +N+ ++A  +   GPL++      ++  Y  GV++  C+   L+H +L+VGY       
Sbjct:  446 KENQLILA--LNEVGPLSVNVGVNNDFVAYSEGVYNGTCS-EELNHSVLLVGYGQVEKTK 502

Query:  302 -------SAKNTIFRKNMP------YWIVKNSWGADWGEQGYIYLRRGKN----TCGVSN 344
                      NT    N P      YWI+KNSW   WGE G++ L R KN     CG+  
Sbjct:  503 LNYNNKIQTYNTKENSNQPDDNIIYYWIIKNSWSKKWGENGFMRLSRNKNGDNVFCGIGE 562

Query:  345 FVSTSII 351
             V   I+
Sbjct:  563 EVFYPIL 569


>sp|P14518|BROM_ANACO BROMELAIN, STEM
          Length = 212

 Score =  139 bits (348), Expect = 6e-33
 Identities = 81/224 (36%), Positives = 113/224 (50%), Gaps = 31/224 (13%)

Query:  125 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEY 184
            + DWR  GAVT VKNQ  CG+CW+F+    VE  + I +  L  LSEQ ++DC       
Sbjct:  5   SIDWRDYGAVTSVKNQNPCGACWAFAAIATVESIYKIKKGILEPLSEQQVLDC------- 57

Query:  185 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKIS 244
pattern 237                                                     ****
                A   GC GG +  A+ +II N G+ + + YPY A  GT C  +    G    A I+
Sbjct:  58  ----AKGYGCKGGWEFRAFEFIISNKGVASGAIYPYKAAKGT-CKTD----GVPNSAYIT 108

Query:  245 NFTMIPKNETVMAGYIVSTGPLAIAADA-VEWQFYIGGVFDIPCNPNSLDHGILIVGYSA 303
             +  +P+N      Y VS  P+ +A DA   +Q+Y  GVF+ PC   SL+H +  +GY  
Sbjct:  109 GYARVPRNNESSMMYAVSKQPITVAVDANANFQYYKSGVFNGPCG-TSLNHAVTAIGYGQ 167

Query:  304 KNTIFRKNMPYWIVKNSWGADWGEQGYIYLRR----GKNTCGVS 343
             + I+ K          WGA WGE GYI + R        CG++
Sbjct:  168 DSIIYPK---------KWGAKWGEAGYIRMARDVSSSSGICGIA 202


>sp|P16311|MMAL_DERFA MAJOR MITE FECAL ALLERGEN DER F 1 PRECURSOR (DER F I)
          Length = 321

 Score =  138 bits (345), Expect = 1e-32
 Identities = 115/352 (32%), Positives = 157/352 (43%), Gaps = 52/352 (14%)

Query:  7   FVLAVFTVFVSSRGIP-PEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLI 65
            FVLA+ ++ V S     P     F EF+  FNK Y+    +E  E+ + N   +E L  +
Sbjct:  3   FVLAIASLLVLSTVYARPASIKTFEEFKKAFNKNYAT---VEEEEVARKNF--LESLKYV 57

Query:  66  AINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEF----INSIPPE 121
              N     K  +N  +DLS DEFKN YL + EA   + L     L+ E     INS+   
Sbjct:  58  EAN-----KGAINHLSDLSLDEFKNRYLMSAEAF--EQLKTQFDLNAETSACRINSVNVP 110

Query:  122 EQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHEC 181
             +   D R+   VTP++ QG CGSCW+FS     E  +   +N  + LSEQ LVDC    
Sbjct:  111 SE--LDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDC---- 164

Query:  182 MEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQA 241
pattern 237                                                        ****
                   A   GC+G   P    YI +NG ++ E SYPY A        NS + G     
Sbjct:  165 -------ASQHGCHGDTIPRGIEYIQQNGVVE-ERSYPYVAREQRCRRPNSQHYG----- 211

Query:  242 KISNFTMIPKNETVMAGYIVSTGPLAIAA-----DAVEWQFYIGGVF---DIPCNPNSLD 293
             ISN+  I   +       ++    AIA      D   +Q Y G      D    PN   
Sbjct:  212 -ISNYCQIYPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNY-- 268

Query:  294 HGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNF 345
            H + IVGY +      +   YWIV+NSW   WG+ GY Y + G N   +  +
Sbjct:  269 HAVNIVGYGS-----TQGDDYWIVRNSWDTTWGDSGYGYFQAGNNLMMIEQY 315


>sp|P42666|CYSP_PLAVI CYSTEINE PROTEINASE PRECURSOR
          Length = 583

 Score =  129 bits (320), Expect = 1e-29
 Identities = 100/370 (27%), Positives = 166/370 (44%), Gaps = 84/370 (22%)

Query:  27  SQFLEFQDKFNKKYSH-EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSS 85
            S+F  F +K+ + Y    E +E+++ FK N  KI++ N          K  VN+F+D S 
Sbjct:  235 SKFFNFMNKYKRSYKDINEQMEKYKNFKMNYLKIKKHN----ETNQMYKMKVNQFSDYSK 290

Query:  86  DEFKNYYLNNKEAIFTDDLPVADYLDDEFI--------------------NSIPPEEQTA 125
             +F++Y        F   +P+ D+L  +++                     ++  +    
Sbjct:  291 KDFESY--------FRKLVPIPDHLKKKYVVPFSSMNNGKGKNVVTSSSGANLLADVPEI 342

Query:  126 FDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNK-LVSLSEQNLVDCDHECMEY 184
             D+R +G V   K+QG CGSCW+F++ GNVE  +    NK +++LSEQ +VDC       
Sbjct:  343 LDYREKGIVHEPKDQGLCGSCWAFASVGNVECMYAKEHNKTILTLSEQEVVDC------- 395

Query:  185 EGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKIS 244
pattern 237                                                     ****
                  + GC+GG    ++ Y I+N GI     Y Y A     C     N   + +  +S
Sbjct:  396 ---SKLNFGCDGGHPFYSFIYAIEN-GICMGDDYKYKAMDNLFC----LNYRCKNKVTLS 447

Query:  245 NFTMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYS- 302
            +   + +NE + A  +   GP+++      ++ FY GG+F+  C    L+H +L+VGY  
Sbjct:  448 SVGGVKENELIRA--LNEVGPVSVNVGVTDDFSFYGGGIFNGTCT-EELNHSVLLVGYGQ 504

Query:  303 -AKNTIFRKN-------------------------MPYWIVKNSWGADWGEQGYIYLRRG 336
               + IF++                            YWI+KNSW   WGE G++ + R 
Sbjct:  505 VQSSKIFQEKNAYDDASGVTKKGALSYPSKADDGIQYYWIIKNSWSKFWGENGFMRISRN 564

Query:  337 KN----TCGV 342
            K      CG+
Sbjct:  565 KEGDNVFCGI 574


>sp|P08176|MMAL_DERPT MAJOR MITE FECAL ALLERGEN DER P 1 PRECURSOR (DER P I)
          Length = 320

 Score =  121 bits (300), Expect = 3e-27
 Identities = 111/345 (32%), Positives = 151/345 (43%), Gaps = 57/345 (16%)

Query:  1   MKVILLFVLAVFTVFVSSRGIPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIE 60
            MK++L     +    V +R   P     F E++  FNK Y+     E  E  + N   +E
Sbjct:  1   MKIVLAIASLLALSAVYAR---PSSIKTFEEYKKAFNKSYAT---FEDEEAARKNF--LE 52

Query:  61  ELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEF----IN 116
             +  +  N  A     +N  +DLS DEFKN +L + EA   + L     L+ E     IN
Sbjct:  53  SVKYVQSNGGA-----INHLSDLSLDEFKNRFLMSAEAF--EHLKTQFDLNAETNACSIN 105

Query:  117 SIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 176
               P E    D R    VTP++ QG CGSCW+FS     E  +   +N+ + L+EQ LVD
Sbjct:  106 GNAPAE---IDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVD 162

Query:  177 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 236
            C           A   GC+G   P    YI  NG +Q ES Y Y A   +    N+   G
Sbjct:  163 C-----------ASQHGCHGDTIPRGIEYIQHNGVVQ-ESYYRYVAREQSCRRPNAQRFG 210

Query:  237 PEEQAKISNFTMI-PKNETVMAGYIVSTGPLAIAA-----DAVEWQFYIGGVF---DIPC 287
pattern 237 ****
                  ISN+  I P N   +   +  T   AIA      D   ++ Y G      D   
Sbjct:  211 ------ISNYCQIYPPNVNKIREALAQTHS-AIAVIIGIKDLDAFRHYDGRTIIQRDNGY 263

Query:  288 NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIY 332
             PN   H + IVGYS       + + YWIV+NSW  +WG+ GY Y
Sbjct:  264 QPNY--HAVNIVGYSN-----AQGVDYWIVRNSWDTNWGDNGYGY 301


>sp|P80067|CATC_RAT DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
            (CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
          Length = 462

 Score =  111 bits (274), Expect = 3e-24
 Identities = 83/260 (31%), Positives = 128/260 (48%), Gaps = 34/260 (13%)

Query:  105 PVADYLDDEFINSIPPEEQTAFDWRT-RGA--VTPVKNQGQCGSCWSFSTTGNVEGQHFI 161
            P+ D +  + + S+P     ++DWR  RG   V+PV+NQ  CGSC+SF++ G +E +  I
Sbjct:  218 PITDEIQQQIL-SLPE----SWDWRNVRGINFVSPVRNQESCGSCYSFASIGMLEARIRI 272

Query:  162 SQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYP 219
              N   +  LS Q +V C              +GC+GG          ++ G+  E+ +P
Sbjct:  273 LTNNSQTPILSPQEVVSCSPYA----------QGCDGGFPYLIAGKYAQDFGVVEENCFP 322

Query:  220 YTAETGTQCN--FNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVE-WQ 276
pattern 237                    ****
            YTA T   C    N       E   +  F     NE +M   +V  GP+A+A +  + + 
Sbjct:  323 YTA-TDAPCKPKENCLRYYSSEYYYVGGFYG-GCNEALMKLELVKHGPMAVAFEVHDDFL 380

Query:  277 FYIGGVF-----DIPCNPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGY 330
             Y  G++       P NP  L +H +L+VGY  K+ +    + YWIVKNSWG+ WGE GY
Sbjct:  381 HYHSGIYHHTGLSDPFNPFELTNHAVLLVGYG-KDPV--TGLDYWIVKNSWGSQWGESGY 437

Query:  331 IYLRRGKNTCGVSNFVSTSI 350
              +RRG + C + +    +I
Sbjct:  438 FRIRRGTDECAIESIAMAAI 457


>sp|P97821|CATC_MOUSE DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
            (CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
          Length = 462

 Score =  109 bits (270), Expect = 9e-24
 Identities = 91/335 (27%), Positives = 155/335 (46%), Gaps = 42/335 (12%)

Query:  34  DKFNKKYSH-----EEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEF 88
            +K N   +H     E Y ER  ++  N   ++ +N +    K+ T     ++  +S  + 
Sbjct:  147 EKVNMNAAHLGGLQERYSER--LYTHNHNFVKAINTV---QKSWTATAYKEYEKMSLRDL 201

Query:  89  KNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRT-RGA--VTPVKNQGQCGS 145
                 +++        P+ D +  + +N   PE   ++DWR  +G   V+PV+NQ  CGS
Sbjct:  202 IRRSGHSQRIPRPKPAPMTDEIQQQILNL--PE---SWDWRNVQGVNYVSPVRNQESCGS 256

Query:  146 CWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAY 203
            C+SF++ G +E +  I  N   +  LS Q +V C              +GC+GG      
Sbjct:  257 CYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYA----------QGCDGGFPYLIA 306

Query:  204 NYIIKNGGIQTESSYPYTA-ETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVS 262
pattern 237                                   ****
                ++ G+  ES +PYTA ++  +   N       +   +  F     NE +M   +V 
Sbjct:  307 GKYAQDFGVVEESCFPYTAKDSPCKPRENCLRYYSSDYYYVGGFYG-GCNEALMKLELVK 365

Query:  263 TGPLAIAADAVE-WQFYIGGVF-----DIPCNPNSL-DHGILIVGYSAKNTIFRKNMPYW 315
             GP+A+A +  + +  Y  G++       P NP  L +H +L+VGY          + YW
Sbjct:  366 HGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVT---GIEYW 422

Query:  316 IVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 350
            I+KNSWG++WGE GY  +RRG + C + +    +I
Sbjct:  423 IIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAI 457


>sp|P25773|CATL_FELCA CATHEPSIN L (PROGESTERONE-DEPENDENT PROTEIN) (PDP)
          Length = 139

 Score =  108 bits (267), Expect = 2e-23
 Identities = 55/145 (37%), Positives = 84/145 (57%), Gaps = 9/145 (6%)

Query:  196 GGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETV 255
pattern 237                                          ****
            GGL  +A+ Y+  NGG+ +E SYPY A+ G  C +   N      A ++++  IP  E  
Sbjct:  1   GGLIDDAFQYVKDNGGLDSEESYPYHAQ-GDSCKYRPEN----SVANVTDYWDIPSKENE 55

Query:  256 MAGYIVSTGPLAIAADAV--EWQFYIGGVF-DIPCNPNSLDHGILIVGYSAKNTIFRKNM 312
            +   + + GP++ A DA    ++FY  G++ D  C+   +DHG+L+VGY A  T   +N 
Sbjct:  56  LMITLAAVGPISAAIDASLDTFRFYKEGIYYDPSCSSEDVDHGVLVVGYGADGTE-TENK 114

Query:  313 PYWIVKNSWGADWGEQGYIYLRRGK 337
             YWI+KNSWG DWG  GYI + + +
Sbjct:  115 KYWIIKNSWGTDWGMDGYIKMAKDR 139


>sp|Q26563|CATC_SCHMA CATHEPSIN C PRECURSOR
          Length = 454

 Score =  108 bits (266), Expect = 3e-23
 Identities = 75/238 (31%), Positives = 109/238 (45%), Gaps = 33/238 (13%)

Query:  126 FDWRT-----RGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLVDCD 178
            FDW +     R  VTP++NQG CGSC++  +   +E +  +  N  +   LS Q +VDC 
Sbjct:  222 FDWTSPPDGSRSPVTPIRNQGICGSCYASPSAAALEARIRLVSNFSEQPILSPQTVVDCS 281

Query:  179 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNF--NSANIG 236
                         EGCNGG          ++ G+  +   PYT E   +C    N     
Sbjct:  282 ----------PYSEGCNGGFPFLIAGKYGEDFGLPQKIVIPYTGEDTGKCTVSKNCTRYY 331

Query:  237 PEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPC-------- 287
pattern 237 ****
              + + I  +     NE +M   ++S GP  +  +  E +QFY  G++            
Sbjct:  332 TTDYSYIGGYYGAT-NEKLMQLELISNGPFPVGFEVYEDFQFYKEGIYHHTTVQTDHYNF 390

Query:  288 NPNSL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 344
            NP  L +H +L+VGY           PYW VKNSWG +WGEQGY  + RG + CGV +
Sbjct:  391 NPFELTNHAVLLVGYGVDKL---SGEPYWKVKNSWGVEWGEQGYFRILRGTDECGVES 445


>sp|P53634|CATC_HUMAN DIPEPTIDYL-PEPTIDASE I PRECURSOR (DPP-I) (DPPI) (CATHEPSIN C)
            (CATHEPSIN J) (DIPEPTIDYL TRANSFERASE)
          Length = 463

 Score =  107 bits (265), Expect = 3e-23
 Identities = 75/235 (31%), Positives = 111/235 (46%), Gaps = 29/235 (12%)

Query:  124 TAFDWRTRGA---VTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCD 178
            T++DWR       V+PV+NQ  CGSC+SF++ G +E +  I  N   +  LS Q +V C 
Sbjct:  233 TSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCS 292

Query:  179 HECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSA--NIG 236
                         +GC GG          ++ G+  E+ +PYT  T + C          
Sbjct:  293 QYA----------QGCEGGFPYLIAGKYAQDFGLVEEACFPYTG-TDSPCKMKEDCFRYY 341

Query:  237 PEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDI-----PCNPN 290
pattern 237 ****
              E   +  F     NE +M   +V  GP+A+A +  + +  Y  G++       P NP 
Sbjct:  342 SSEYHYVGGFYG-GCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPF 400

Query:  291 SL-DHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 344
             L +H +L+VGY   +      M YWIVKNSWG  WGE GY  +RRG + C + +
Sbjct:  401 ELTNHAVLLVGYGTDSA---SGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIES 452


>sp|P25780|EUM1_EURMA MITE GROUP I ALLERGEN EUR M 1 (EUR M I)
          Length = 211

 Score = 99.8 bits (245), Expect = 7e-21
 Identities = 73/228 (32%), Positives = 102/228 (44%), Gaps = 33/228 (14%)

Query:  117 SIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVD 176
            S+P E     D R+   VTP++ QG CGSCW+FS   + E  +   +N  + L+EQ LVD
Sbjct:  10  SLPSE----LDLRSLRTVTPIRMQGGCGSCWAFSGVASTESAYLAYRNMSLDLAEQELVD 65

Query:  177 CDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQCNFNSANIG 236
            C           A   GC+G   P    YI +NG +Q E  YPY A   +    N+   G
Sbjct:  66  C-----------ASQNGCHGDTIPRGIEYIQQNGVVQ-EHYYPYVAREQSCHRPNAQRYG 113

Query:  237 PEEQAKISNFTMIPKNETVMAGYIVSTGPLAI---AADAVEWQFYIGGVF---DIPCNPN 290
pattern 237 ****
             +   +IS     P +  +      +   +A+     D   ++ Y G      D    PN
Sbjct:  114 LKNYCQISP----PDSNKIRQALTQTHTAVAVIIGIKDLNAFRHYDGRTIMQHDNGYQPN 169

Query:  291 SLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKN 338
               H + IVGY   NT   + + YWIV+NSW   WG+ GY Y     N
Sbjct:  170 Y--HAVNIVGYG--NT---QGVDYWIVRNSWDTTWGDNGYGYFAANIN 210


>sp|Q23894|CYS3_DICDI CYSTEINE PROTEINASE 3 (CYSTEINE PROTEINASE II)
          Length = 151

 Score = 94.8 bits (232), Expect = 2e-19
 Identities = 60/158 (37%), Positives = 87/158 (54%), Gaps = 15/158 (9%)

Query: 41  SHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIF 100
           +H+E++ R+E FK N+  +   N    +  + T  G+N+ ADLS++E++  YL  +  I 
Sbjct: 1   THKEFMPRYEEFKKNMDYVHNWN----SKGSKTVLGLNQHADLSNEEYRLNYLGTRAHIK 56

Query: 101 TDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHF 160
            +     +      +N    ++    DWR + AVTPVK+QGQCGSC   STTG+VEG   
Sbjct: 57  LNGYHKRNL--GLRLNRPHFKQPLNVDWREKDAVTPVKDQGQCGSC-IISTTGSVEGVTA 113

Query: 161 ISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGL 198
           I   KLVSLSEQN++               +EGCNGGL
Sbjct: 114 IKTGKLVSLSEQNILRL--------SSSFGNEGCNGGL 143


>sp|P43509|CPR5_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 5 PRECURSOR
          Length = 344

 Score = 90.9 bits (222), Expect = 4e-18
 Identities = 69/272 (25%), Positives = 111/272 (40%), Gaps = 47/272 (17%)

Query:  108 DYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLV 167
            D +  E  ++IP        W    ++  +++Q  CGSCW+F+    +  +  I+ N  V
Sbjct:  72  DIVATEVSDAIPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAV 131

Query:  168 S--LSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSY------- 218
            +  LS ++L+ C        G  +C  GC GG    A+ + +K+G + T  SY       
Sbjct:  132 NTLLSSEDLLSC------CTGMFSCGNGCEGGYPIQAWKWWVKHG-LVTGGSYETQFGCK 184

Query:  219 PY-----------------------TAETGTQCNFNSANIGPEEQAKISNFTM--IPKNE 253
pattern 237                                          ****
            PY                       T +    C   +    P  Q K    T   + K  
Sbjct:  185 PYSIAPCGETVNGVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKV 244

Query:  254 TVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNM 312
              +   I++ GP+ +A    E +  Y  GV+      +   H + I+G+   N       
Sbjct:  245 EQIQTEILTNGPIEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDN-----GT 299

Query:  313 PYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 344
            PYW+V NSW   WGE+GY  + RG N CG+ +
Sbjct:  300 PYWLVANSWNVAWGEKGYFRIIRGLNECGIEH 331


>sp|P43508|CPR4_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 4 PRECURSOR
          Length = 335

 Score = 90.5 bits (221), Expect = 5e-18
 Identities = 73/299 (24%), Positives = 124/299 (41%), Gaps = 50/299 (16%)

Query:  82  DLSSDEFKNYYLNNK-EAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQ 140
            D++ ++ K   +  +  A  T D+ V  +  +E  ++IP        W    ++  +++Q
Sbjct:  46  DITIEQVKKRLMRTEFVAPHTPDVEVVKHDINE--DTIPATFDARTQWPNCMSINNIRDQ 103

Query:  141 GQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGL 198
              CGSCW+F+       +  I+ N  V+  LS ++++ C   C        C  GC GG 
Sbjct:  104 SDCGSCWAFAAAEAASDRFCIASNGAVNTLLSAEDVLSC---CSN------CGYGCEGGY 154

Query:  199 QPNAYNYIIKNG---GIQTESSYPYTAETGTQCNFNSANI--------GPEEQAKISNFT 247
pattern 237                                                  ****
              NA+ Y++K+G   G   E+ +     +   C     N+        G +  A ++  T
Sbjct:  155 PINAWKYLVKSGFCTGGSYEAQFGCKPYSLAPCGETVGNVTWPSCPDDGYDTPACVNKCT 214

Query:  248 -------------------MIPKNETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPC 287
                                + K  + +   I++ GP+  A    E +  Y  GV+    
Sbjct:  215 NKNYNVAYTADKHFGSTAYAVGKKVSQIQAEIIAHGPVEAAFTVYEDFYQYKTGVYVHTT 274

Query:  288 NPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFV 346
                  H I I+G+   N       PYW+V NSW  +WGE GY  + RG N CG+ + V
Sbjct:  275 GQELGGHAIRILGWGTDN-----GTPYWLVANSWNVNWGENGYFRIIRGTNECGIEHAV 328


>sp|P05993|PAP5_CARPA CYSTEINE PROTEINASE (CLONE PLBPC13)
          Length = 96

 Score = 90.5 bits (221), Expect = 5e-18
 Identities = 43/87 (49%), Positives = 55/87 (62%), Gaps = 2/87 (2%)

Query: 264 GPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN--TIFRKNMPYWIVKNSW 321
           GPLA+A +A   Q YIGGV         L+HG+L+VGY +     I  K  PYW++KNSW
Sbjct: 1   GPLAVAINAAYMQTYIGGVSCPYICSRRLNHGVLLVGYGSAGYAPIRLKEKPYWVIKNSW 60

Query: 322 GADWGEQGYIYLRRGKNTCGVSNFVST 348
           G +WGE GY  + RG+N CGV + VST
Sbjct: 61  GENWGENGYYKICRGRNICGVDSMVST 87


>sp|P07688|CATB_BOVIN CATHEPSIN B PRECURSOR
          Length = 335

 Score = 88.5 bits (216), Expect = 2e-17
 Identities = 65/259 (25%), Positives = 105/259 (40%), Gaps = 47/259 (18%)

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL---SEQNL 174
            +P        W     +  +++QG CGSCW+F     +  +  I  N  V++   +E  L
Sbjct:  80  LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 139

Query:  175 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ--------------------- 213
              C  EC          +GCNGG    A+N+  K G +                      
Sbjct:  140 TCCGGEC---------GDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHH 190

Query:  214 -TESSYPYTAETGT-QCNFN-----SANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPL 266
pattern 237                               ****
               S  P T E  T +CN       S +   ++    S++++    + +MA  I   GP+
Sbjct:  191 VNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAE-IYKNGPV 249

Query:  267 AIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 325
              A     ++  Y  GV+          H I I+G+  +N       PYW+V NSW  DW
Sbjct:  250 EGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVEN-----GTPYWLVGNSWNTDW 304

Query:  326 GEQGYIYLRRGKNTCGVSN 344
            G+ G+  + RG++ CG+ +
Sbjct:  305 GDNGFFKILRGQDHCGIES 323


>sp|P00787|CATB_RAT CATHEPSIN B PRECURSOR (CATHEPSIN B1) (RSG-2)
          Length = 339

 Score = 87.4 bits (213), Expect = 4e-17
 Identities = 66/265 (24%), Positives = 113/265 (41%), Gaps = 45/265 (16%)

Query:  117 SIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL--SEQNL 174
            ++P        W     +  +++QG CGSCW+F     +  +  I  N  V++  S ++L
Sbjct:  79  NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 138

Query:  175 VDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIK----NGGIQTE--------------- 215
            + C   C        C +GCNGG    A+N+  +    +GG+                  
Sbjct:  139 LTC---C-----GIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHH 190

Query:  216 ---SSYPYTAETGT-QCNFN-----SANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPL 266
pattern 237                               ****
               S  P T E  T +CN       S +   ++    +++++    + +MA  I   GP+
Sbjct:  191 VNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAE-IYKNGPV 249

Query:  267 AIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 325
              A     ++  Y  GV+          H I I+G+  +N +     PYW+V NSW  DW
Sbjct:  250 EGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGV-----PYWLVANSWNVDW 304

Query:  326 GEQGYIYLRRGKNTCGVSNFVSTSI 350
            G+ G+  + RG+N CG+ + +   I
Sbjct:  305 GDNGFFKILRGENHCGIESEIVAGI 329


>sp|P25807|CYS1_CAEEL GUT-SPECIFIC CYSTEINE PROTEINASE PRECURSOR
          Length = 329

 Score = 87.0 bits (212), Expect = 5e-17
 Identities = 66/288 (22%), Positives = 117/288 (39%), Gaps = 38/288 (13%)

Query:  82  DLSSDEFKNYYLNNK-EAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQ 140
            +++ +E K   ++ K  A  +D++   +   +  + S+P    +   W    ++  +++Q
Sbjct:  50  EITEEEMKFKLMDGKYAAAHSDEIRATE--QEVVLASVPATFDSRTQWSECKSIKLIRDQ 107

Query:  141 GQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYEGEEACDEGCNGGL 198
              CGSCW+F     +  +  I         +S  +L+ C   C       +C  GC GG 
Sbjct:  108 ATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLLSC---C-----GSSCGNGCEGGY 159

Query:  199 QPNAYNY-----IIKNGGIQTESSYPYTAETGTQ----------CNFNSANIGPEEQAKI 243
pattern 237                                                      ****
               A  +     ++  G        PY     T           C+ +  +      AK 
Sbjct:  160 PIQALRWWDSKGVVTGGDYHGAGCKPYPIAPCTSGNCPESKTPSCSMSCQSGYSTAYAKD 219

Query:  244 SNFTM----IPKNETVMAGYIVSTGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILI 298
             +F +    +PKN   +   I + GP+  A    E +  Y  GV+          H I I
Sbjct:  220 KHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDFYKYKSGVYKHTAGKYLGGHAIKI 279

Query:  299 VGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFV 346
            +G+  ++       PYW+V NSWG +WGE G+  + RG + CG+ + V
Sbjct:  280 IGWGTES-----GSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESAV 322


>sp|P07858|CATB_HUMAN CATHEPSIN B PRECURSOR (CATHEPSIN B1) (APP SECRETASE)
          Length = 339

 Score = 86.2 bits (210), Expect = 9e-17
 Identities = 68/285 (23%), Positives = 110/285 (37%), Gaps = 55/285 (19%)

Query:  96  KEAIFTDDLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNV 155
            +  +FT+DL             +P        W     +  +++QG CGSCW+F     +
Sbjct:  70  QRVMFTEDL------------KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAI 117

Query:  156 EGQHFISQNKLVSL--SEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ 213
              +  I  N  VS+  S ++L+ C   C        C +GCNGG    A+N+  + G + 
Sbjct:  118 SDRICIHTNAHVSVEVSAEDLLTC---C-----GSMCGDGCNGGYPAEAWNFWTRKGLVS 169

Query:  214 ----------------------TESSYPYTAETGTQ-----CNFNSANIGPEEQAKISNF 246
pattern 237                                                   ****
                                    S  P T E  T      C    +    +++    N 
Sbjct:  170 GGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNS 229

Query:  247 TMIPKNETVMAGYIVSTGPLAIAADAV-EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKN 305
              +  +E  +   I   GP+  A     ++  Y  GV+          H I I+G+  +N
Sbjct:  230 YSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVEN 289

Query:  306 TIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSI 350
                   PYW+V NSW  DWG+ G+  + RG++ CG+ + V   I
Sbjct:  290 -----GTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGI 329


>sp|P43157|CYSP_SCHJA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECURSOR (ANTIGEN SJ31)
          Length = 342

 Score = 85.4 bits (208), Expect = 2e-16
 Identities = 64/271 (23%), Positives = 109/271 (39%), Gaps = 57/271 (21%)

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQ--NKLVSLSEQNLV 175
            IP +  +   W    +++ +++Q +CGSCW+F     +  +  I     +   LS  +L+
Sbjct:  90  IPSQFDSRKKWPHCKSISQIRDQSRCGSCWAFGAVEAMTDRICIQSGGGQSAELSALDLI 149

Query:  176 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGI---------------------QT 214
             C   C +      C +GC GG    A++Y +K G +                      T
Sbjct:  150 SC---CKD------CGDGCQGGFPGVAWDYWVKRGIVTGGSKENHTGCQPYPFPKCEHHT 200

Query:  215 ESSYP-------------YTAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIV 261
pattern 237                                    ****
            +  YP              T + G +  +       +E   + N      NE V+   I+
Sbjct:  201 KGKYPACGTKIYKTPQCKQTCQKGYKTPYEQDKHYGDESYNVQN------NEKVIQRDIM 254

Query:  262 STGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNS 320
              GP+  A D  E +  Y  G++          H I I+G+  +     K  PYW++ NS
Sbjct:  255 MYGPVEAAFDVYEDFLNYKSGIYRHVTGSIVGGHAIRIIGWGVE-----KRTPYWLIANS 309

Query:  321 WGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            W  DWGE+G   + RG++ C + + V   +I
Sbjct:  310 WNEDWGEKGLFRMVRGRDECSIESDVVAGLI 340


>sp|P43233|CATB_CHICK CATHEPSIN B PRECURSOR (CATHEPSIN B1)
          Length = 340

 Score = 85.4 bits (208), Expect = 2e-16
 Identities = 66/265 (24%), Positives = 111/265 (40%), Gaps = 46/265 (17%)

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL--SEQNLV 175
            +P    T   W     ++ +++QG CGSCW+F     +  +  +  N  VS+  S ++L+
Sbjct:  80  LPDTFDTRKQWPNCPTISEIRDQGSCGSCWAFGAVEAISDRICVHTNAKVSVEVSAEDLL 139

Query:  176 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ---------------------- 213
             C   C    G E C  GCNGG    A+ Y  + G +                       
Sbjct:  140 SC---C----GFE-CGMGCNGGYPSGAWRYWTERGLVSGGLYDSHVGCRAYTIPPCEHHV 191

Query:  214 TESSYPYTAETGT--QCNFN-----SANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPL 266
pattern 237                               ****
              S  P T E G   +C+ +     S +   ++   I+++  +P++E  +   I   GP+
Sbjct:  192 NGSRPPCTGEGGETPRCSRHCEPGYSPSYKEDKHYGITSYG-VPRSEKEIMAEIYKNGPV 250

Query:  267 AIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 325
              A    E +  Y  GV+          H I I+G+  +N       PYW+  NSW  DW
Sbjct:  251 EGAFIVYEDFLMYKSGVYQHVSGEQVGGHAIRILGWGVEN-----GTPYWLAANSWNTDW 305

Query:  326 GEQGYIYLRRGKNTCGVSNFVSTSI 350
            G  G+  + RG++ CG+ + +   +
Sbjct:  306 GITGFFKILRGEDHCGIESEIVAGV 330


>sp|P43510|CPR6_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PRECURSOR
          Length = 379

 Score = 85.0 bits (207), Expect = 2e-16
 Identities = 71/265 (26%), Positives = 116/265 (42%), Gaps = 53/265 (20%)

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNK--LVSLSEQNLV 175
            IP    +  +W    ++  +++Q  CGSCW+F     +  +  I+ +    V+LS  +L+
Sbjct:  105 IPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLL 164

Query:  176 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETGTQ------CN 229
             C   C      ++C  GCNGG    A+ Y +K+G I T S+Y  TA  G +      C 
Sbjct:  165 SC---C------KSCGFGCNGGDPLAAWRYWVKDG-IVTGSNY--TANNGCKPYPFPPCE 212

Query:  230 FNSANIGPE------------EQAKISNFTMIPKNETVMAGY---------------IVS 262
pattern 237        **            **
             +S     +            E+  +S++T    +E    G                +++
Sbjct:  213 HHSKKTHFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMT 272

Query:  263 TGPLAIAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSW 321
             GPL IA +  E +  Y GGV+          H + ++G+   + I     PYW V NSW
Sbjct:  273 HGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGI-----PYWTVANSW 327

Query:  322 GADWGEQGYIYLRRGKNTCGVSNFV 346
              DWGE G+  + RG + CG+ + V
Sbjct:  328 NTDWGEDGFFRILRGVDECGIESGV 352


>sp|P25792|CYSP_SCHMA CATHEPSIN B-LIKE CYSTEINE PROTEINASE PRECURSOR (ANTIGEN SM31)
          Length = 340

 Score = 84.6 bits (206), Expect = 3e-16
 Identities = 64/260 (24%), Positives = 107/260 (40%), Gaps = 45/260 (17%)

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLV 175
            IP    +   W    ++  +++Q +CGSCWSF     +  +  I     + V LS  +L+
Sbjct:  89  IPSNFDSRKKWPGCKSIATIRDQSRCGSCWSFGAVEAMSDRSCIQSGGKQNVELSAVDLL 148

Query:  176 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTA---ETGTQCNFNS 232
             C   C      E+C  GC GG+   A++Y +K G +   S   +T        +C  ++
Sbjct:  149 TC---C------ESCGLGCEGGILGPAWDYWVKEGIVTASSKENHTGCEPYPFPKCEHHT 199

Query:  233 ANIGPEEQAKISN---------------FTM----------IPKNETVMAGYIVSTGPLA 267
pattern 237     ****
                P   +KI N               +T           +  +E  +   I+  GP+ 
Sbjct:  200 KGKYPPCGSKIYNTPRCKQTCQRKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVE 259

Query:  268 IAADAVE-WQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWG 326
             +    E +  Y  G++          H I I+G+  +N       PYW++ NSW  DWG
Sbjct:  260 ASFTVYEDFLNYKSGIYKHITGEALGGHAIRIIGWGVEN-----KTPYWLIANSWNEDWG 314

Query:  327 EQGYIYLRRGKNTCGVSNFV 346
            E GY  + RG++ C + + V
Sbjct:  315 ENGYFRIVRGRDECSIESEV 334


>sp|P10605|CATB_MOUSE CATHEPSIN B PRECURSOR (CATHEPSIN B1)
          Length = 339

 Score = 84.6 bits (206), Expect = 3e-16
 Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 43/253 (16%)

Query:  128 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSL--SEQNLVDCDHECMEYE 185
            W     +  +++QG CGSCW+F     +  +  I  N  V++  S ++L+ C   C    
Sbjct:  90  WSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTC---C---- 142

Query:  186 GEEACDEGCNGGLQPNAYNYIIK----NGGIQTE------------------SSYPYTAE 223
                C +GCNGG    A+++  K    +GG+                     S  P T E
Sbjct:  143 -GIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGE 201

Query:  224 TGT-QCNFN-SANIGPE-EQAKISNFTMIPKNETV--MAGYIVSTGPLAIAADAV-EWQF 277
pattern 237                ** **
              T +CN +  A   P  ++ K   +T    + +V  +   I   GP+  A     ++  
Sbjct:  202 GDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLT 261

Query:  278 YIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGK 337
            Y  GV+          H I I+G+  +N +     PYW+  NSW  DWG+ G+  + RG+
Sbjct:  262 YKSGVYKHEAGDMMGGHAIRILGWGVENGV-----PYWLAANSWNLDWGDNGFFKILRGE 316

Query:  338 NTCGVSNFVSTSI 350
            N CG+ + +   I
Sbjct:  317 NHCGIESEIVAGI 329


>sp|P25802|CYS1_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PRECURSOR
          Length = 341

 Score = 79.6 bits (193), Expect = 9e-15
 Identities = 63/270 (23%), Positives = 106/270 (38%), Gaps = 46/270 (17%)

Query:  103 DLPVADYLDDEFINSIPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFIS 162
            D  V D   +E  + IP        W    ++  + +Q  CGSCW+ S+   +  +  I+
Sbjct:  76  DEEVEDEELEENNDDIPESYDPRIQWANCSSLFHIPDQANCGSCWAVSSAAAMSDRICIA 135

Query:  163 QN--KLVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNY-----IIKNGGIQTE 215
                K V +S Q++V C   C        C +GC GG   +A+ +     ++  G   T+
Sbjct:  136 SKGAKQVLISAQDVVSC---CTW------CGDGCEGGWPISAFRFHADEGVVTGGDYNTK 186

Query:  216 SSY-PYTAET----GTQCNFNSANIGPEEQAKISNFTMI------PKNETVMAGYIVSTG 264
pattern 237                           ****
             S  PY        G +  +    +G  +  +     ++      P +      Y +   
Sbjct:  187 GSCRPYEIHPCGHHGNETYYGEC-VGMADTPRCKRRCLLGYPKSYPSDRYYKKAYQLKNS 245

Query:  265 PLAIAADAV-------------EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKN 311
              AI  D +             ++  Y  G++       +  H + ++G+  +     K 
Sbjct:  246 VKAIQKDIMKNGPVVATYTVYEDFAHYRSGIYKHKAGRKTGLHAVKVIGWGEE-----KG 300

Query:  312 MPYWIVKNSWGADWGEQGYIYLRRGKNTCG 341
             PYWIV NSW  DWGE G+  + RG N CG
Sbjct:  301 TPYWIVANSWHDDWGENGFFRMHRGSNDCG 330


>sp|P25793|CYS2_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 2 PRECURSOR
          Length = 342

 Score = 78.4 bits (190), Expect = 2e-14
 Identities = 59/266 (22%), Positives = 110/266 (41%), Gaps = 47/266 (17%)

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLV 175
            IPP       W+       +++Q  CGSCW+ ST   +  +  I+    K V++S  +++
Sbjct:  87  IPPSYDPRDVWKNCTTFY-IRDQANCGSCWAVSTAAAISDRICIASKAEKQVNISATDIM 145

Query:  176 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ------TESSYPY--------- 220
             C   C        C +GC GG    A+ Y I +G +        +   PY         
Sbjct:  146 TC---C-----RPQCGDGCEGGWPIEAWKYFIYDGVVSGGEYLTKDVCRPYPIHPCGHHG 197

Query:  221 -------------TAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLA 267
pattern 237                              ****
                         T     +C      +   ++    +  ++ ++   +   I+  GP+ 
Sbjct:  198 NDTYYGECRGTAPTPPCKRKCRPGVRKMYRIDKRYGKDAYIVKQSVKAIQSEILKNGPV- 256

Query:  268 IAADAV--EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 325
            +A+ AV  +++ Y  G++          H + ++G+  +N     N  +W++ NSW  DW
Sbjct:  257 VASFAVYEDFRHYKSGIYKHTAGELRGYHAVKMIGWGNEN-----NTDFWLIANSWHNDW 311

Query:  326 GEQGYIYLRRGKNTCGVSNFVSTSII 351
            GE+GY  + RG N CG+   ++  I+
Sbjct:  312 GEKGYFRIVRGSNDCGIEGTIAAGIV 337


>sp|P19092|CYS1_HAECO CATHEPSIN B-LIKE CYSTEINE PROTEINASE 1 PRECURSOR
          Length = 342

 Score = 77.6 bits (188), Expect = 4e-14
 Identities = 59/266 (22%), Positives = 110/266 (41%), Gaps = 47/266 (17%)

Query:  118 IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQN--KLVSLSEQNLV 175
            IPP       W+       +++Q  CGSCW+ ST   +  +  I+    K V++S  +++
Sbjct:  87  IPPSYDPRDVWKNCTTFY-IRDQANCGSCWAVSTAAAISDRICIASKAEKQVNISATDIM 145

Query:  176 DCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQ------TESSYPY--------- 220
             C   C        C +GC GG    A+ Y I +G +        +   PY         
Sbjct:  146 TC---C-----RPQCGDGCEGGWPIEAWKYFIYDGVVSGGEYLTKDVCRPYPIHPCGHHG 197

Query:  221 -------------TAETGTQCNFNSANIGPEEQAKISNFTMIPKNETVMAGYIVSTGPLA 267
pattern 237                              ****
                         T     +C      +   ++    +  ++ ++   +   I+  GP+ 
Sbjct:  198 NDTYYGECRGTAPTPPCKRKCRPGVRKMYRIDKRYGKDAYIVKQSVKAIQSEILRNGPV- 256

Query:  268 IAADAV--EWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADW 325
            +A+ AV  +++ Y  G++          H + ++G+  +N     N  +W++ NSW  DW
Sbjct:  257 VASFAVYEDFRHYKSGIYKHTAGELRGYHAVKMIGWGNEN-----NTDFWLIANSWHNDW 311

Query:  326 GEQGYIYLRRGKNTCGVSNFVSTSII 351
            GE+GY  + RG N CG+   ++  I+
Sbjct:  312 GEKGYFRIIRGTNDCGIEGTIAAGIV 337


>sp|P43507|CPR3_CAEEL CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3 PRECURSOR
          Length = 370

 Score = 73.3 bits (177), Expect = 7e-13
 Identities = 56/248 (22%), Positives = 98/248 (38%), Gaps = 39/248 (15%)

Query:  128 WRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS--LSEQNLVDCDHECMEYE 185
            W     +  ++NQ  CGSCW+F     +  +  I  N      +S ++++ C   C    
Sbjct:  102 WPDCNTIKLIRNQATCGSCWAFGAAEVISDRVCIQSNGTQQPVISVEDILSC---C---- 154

Query:  186 GEEACDEGCNGGLQPNAYNYIIKNGGIQ---------------------TESSYPYTAET 224
                C  GC GG    A  +   +G +                       ES+ P + +T
Sbjct:  155 -GTTCGYGCKGGYSIEALRFWASSGAVTGGDYGGHGCMPYSFAPCTKNCPESTTP-SCKT 212

Query:  225 GTQCNFNSANIGPEEQAKISNFTMIP-KNETVMAGYIVSTGPLAIAADAVE-WQFYIGGV 282
pattern 237             ****
              Q ++ +     ++    S + +   K+ T +   I   GP+  +    E +  Y  GV
Sbjct:  213 TCQSSYKTEEYKKDKHYGASAYKVTTTKSVTEIQTEIYHYGPVEASYKVYEDFYHYKSGV 272

Query:  283 FDIPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGV 342
            +          H + I+G+  +N +      YW++ NSWG  +GE+G+  +RRG N C +
Sbjct:  273 YHYTSGKLVGGHAVKIIGWGVENGV-----DYWLIANSWGTSFGEKGFFKIRRGTNECQI 327

Query:  343 SNFVSTSI 350
               V   I
Sbjct:  328 EGNVVAGI 335


>sp|P13823|SERA_PLAFG SERINE-REPEAT ANTIGEN PROTEIN PRECURSOR (P126) (111 KD ANTIGEN)
          Length = 989

 Score = 70.2 bits (169), Expect = 6e-12
 Identities = 63/247 (25%), Positives = 102/247 (40%), Gaps = 46/247 (18%)

Query:  137 VKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGE--EACDEGC 194
            V++QG C + W F++  ++E    +   +   +S   + +C      Y+GE  + CDEG 
Sbjct:  579 VEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANC------YKGEHKDRCDEGS 632

Query:  195 NGGLQPNAYNYIIKNGG-IQTESSYPYT-AETGTQC------------------NFNSAN 234
            +    P  +  II++ G +  ES+YPY   + G QC                  N N  N
Sbjct:  633 S----PMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPN 688

Query:  235 I----------GPEEQAKISNFTMIPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFD 284
pattern 237             ****
                              +  F  I K E +  G +++     I A+ V    + G    
Sbjct:  689 SLDGKGYTAYESERFHDNMDAFVKIIKTEVMNKGSVIAY----IKAENVMGYEFSGKKVQ 744

Query:  285 IPCNPNSLDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSN 344
              C  ++ DH + IVGY        +   YWIV+NSWG  WG++GY  +     T    N
Sbjct:  745 NLCGDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHCHFN 804

Query:  345 FVSTSII 351
            F+ + +I
Sbjct:  805 FIHSVVI 811


>sp|P32956|CC3_CARCN CYSTEINE PROTEINASE III (CC-III)
          Length = 43

 Score = 60.9 bits (145), Expect = 4e-09
 Identities = 24/33 (72%), Positives = 27/33 (81%)

Query: 125 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 157
           + DWR +GAVTPVKNQG CGSCW+FST   VEG
Sbjct: 4   SIDWRKKGAVTPVKNQGSCGSCWAFSTIATVEG 36


>sp|P32957|CC4_CARCN CYSTEINE PROTEINASE IV (CC-IV)
          Length = 43

 Score = 59.7 bits (142), Expect = 9e-09
 Identities = 24/33 (72%), Positives = 27/33 (81%)

Query: 125 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 157
           + DWR +GAVTPVKNQG CGSCW+FST   VEG
Sbjct: 4   SIDWRKKGAVTPVKNQGSCGSCWAFSTIVTVEG 36


>sp|Q06544|CYS3_OSTOS CATHEPSIN B-LIKE CYSTEINE PROTEINASE 3
          Length = 174

 Score = 59.3 bits (141), Expect = 1e-08
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 15/103 (14%)

Query: 249 IPKNETVMAGYIVSTGPLAIAADAVEWQFYIGGVFDIPCNPNSLDHGILIVGYSAKNTIF 308
           I KN  V+AG+IV            ++  Y  G++       +  H + I+G+  +    
Sbjct: 87  IMKNGPVVAGFIVYE----------DFAHYKSGIYKHTAGRMTGGHAVKIIGWGKE---- 132

Query: 309 RKNMPYWIVKNSWGADWGEQGYIYLRRGKNTCGVSNFVSTSII 351
            K  PYW++ NSW  DWGE+G+  + RG N C +   V   I+
Sbjct: 133 -KGTPYWLIANSWHDDWGEKGFYRMIRGINNCRIEEMVFAGIV 174


>sp|P32954|CC1_CARCN CYSTEINE PROTEINASE I (CC-I)
          Length = 43

 Score = 57.8 bits (137), Expect = 3e-08
 Identities = 22/33 (66%), Positives = 27/33 (81%)

Query: 125 AFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 157
           + DWR +GAVTPV+NQG CGSCW+FS+   VEG
Sbjct: 4   SIDWRQKGAVTPVRNQGSCGSCWTFSSVAAVEG 36


>sp|P32955|CC2_CARCN CYSTEINE PROTEINASE II (CC-II)
          Length = 43

 Score = 56.2 bits (133), Expect = 1e-07
 Identities = 22/31 (70%), Positives = 25/31 (79%)

Query: 127 DWRTRGAVTPVKNQGQCGSCWSFSTTGNVEG 157
           DWR +GAVTPVK+Q  CGSCW+FST   VEG
Sbjct: 6   DWRQKGAVTPVKDQNPCGSCWAFSTVATVEG 36


>sp||CATL_CHICK_2 [Segment 2 of 2] CATHEPSIN L
          Length = 42

 Score = 51.9 bits (122), Expect = 2e-06
 Identities = 20/39 (51%), Positives = 28/39 (71%), Gaps = 1/39 (2%)

Query: 314 YWIVKNSWGADWGEQGYIYLRRG-KNTCGVSNFVSTSII 351
           YWIVKNSWG  WG++GYIY+ +  KN CG++   S  ++
Sbjct: 4   YWIVKNSWGEKWGDKGYIYMAKDRKNHCGIATAASYPLV 42


>sp|P12399|CT2A_MOUSE CTLA-2-ALPHA PROTEIN PRECURSOR
          Length = 136

 Score = 41.8 bits (96), Expect = 0.002
 Identities = 31/101 (30%), Positives = 50/101 (48%), Gaps = 4/101 (3%)

Query: 9   LAVFTVFVSSRGIPPEEQ--SQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIA 66
           L +  + + S   PP+    +++ E++ KF K Y+  E   R  +++ N  KIE  N   
Sbjct: 17  LLILCLGMMSAAPPPDPSLDNEWKEWKTKFAKAYNLNEERHRRLVWEENKKKIEAHNADY 76

Query: 67  INHKADTKFGVNKFADLSSDEFK-NYYLNN-KEAIFTDDLP 105
              K     G+N+F+DL+ +EFK N Y N+        DLP
Sbjct: 77  EQGKTSFYMGLNQFSDLTPEEFKTNCYGNSLNRGEMAPDLP 117


>sp|P05689|CATX_BOVIN CATHEPSIN
          Length = 73

 Score = 40.2 bits (92), Expect = 0.006
 Identities = 15/40 (37%), Positives = 24/40 (59%), Gaps = 5/40 (12%)

Query: 292 LDHGILIVGYSAKNTIFRKNMPYWIVKNSWGADWGEQGYI 331
           ++H + + G+   +      M YWIV+NSWG  WGE G++
Sbjct: 9   INHIVSVAGWGVSD-----GMEYWIVRNSWGEPWGEHGWM 43


>sp|P12400|CT2B_MOUSE CTLA-2-BETA PROTEIN PRECURSOR
          Length = 141

 Score = 38.7 bits (88), Expect = 0.019
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)

Query: 6   LFVLAVFTVFVSSRGIP-PEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNL 64
           +F+L +    +S+   P P   +++ E++  F K YS +E   R  +++ N  KIE  N 
Sbjct: 20  VFLLILCLGMMSAAPSPDPSLDNEWKEWKTTFAKAYSLDEERHRRLMWEENKKKIEAHNA 79

Query: 65  IAINHKADTKFGVNKFADLSSDEFK 89
                K     G+N+F+DL+ +EF+
Sbjct: 80  DYERGKTSFYMGLNQFSDLTPEEFR 104


>sp|P23897|HSER_RAT HEAT-STABLE ENTEROTOXIN RECEPTOR PRECURSOR (GC-C) (INTESTINAL
           GUANYLATE CYCLASE) (STA RECEPTOR)
          Length = 1072

 Score = 35.6 bits (80), Expect = 0.16
 Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 19/120 (15%)

Query: 15  FVSSRGIPPEEQSQFLEFQDK----FNKKYSHEEYLERFEIFKSNL-GKIEELNLIAINH 69
           +V   G  PE+   +L   +     F++  S ++ L R E F+  L G+  + N+I +  
Sbjct: 190 YVYKNGSEPEDCFWYLNALEAGVSYFSEVLSFKDVLRRSEQFQEILMGRNRKSNVIVMCG 249

Query: 70  KADTKFGVN---KFAD----LSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEE 122
             +T + V    K AD    +  D F N+Y       F DD    +Y+D+  + ++PPE+
Sbjct: 250 TPETFYNVKGDLKVADDTVVILVDLFSNHY-------FEDDTRAPEYMDNVLVLTLPPEK 302


>sp|P20736|BM86_BOOMI GLYCOPROTEIN ANTIGEN BM86 PRECURSOR (PROTECTIVE ANTIGEN)
          Length = 650

 Score = 35.2 bits (79), Expect = 0.22
 Identities = 24/81 (29%), Positives = 36/81 (43%), Gaps = 5/81 (6%)

Query: 151 TTGNVEGQHFISQNKLVSLSEQNLVDC----DHECMEYEGEEACDEGCNGGLQPNAYNYI 206
           TT N +        KL  + + +  +C    DHEC     +++C E  NG  Q +    +
Sbjct: 533 TTCNPKEIQECQDKKLECVYKNHKAECECPDDHECYREPAKDSCSEEDNGKCQSSGQRCV 592

Query: 207 IKNG-GIQTESSYPYTAETGT 226
           I+NG  +  E S   TA T T
Sbjct: 593 IENGKAVCKEKSEATTAATTT 613


>sp|P46992|YJR1_YEAST HYPOTHETICAL 43.0 KD PROTEIN IN CPS1-FPP1 INTERGENIC REGION
          Length = 396

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 39/191 (20%), Positives = 77/191 (39%), Gaps = 39/191 (20%)

Query: 77  VNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINSIPPEE-------------- 122
           VNKF D++++E     + ++      + P+ADYL   F   +  ++              
Sbjct: 42  VNKFKDITNNESCTCEVGDRVWFSGKNAPLADYLSVHFRGPLKLKQFAFYTSPGFTVNNS 101

Query: 123 QTAFDW----------RTRGAVTPVKNQGQCGSCW-------SFSTTGNVEGQHFISQNK 165
           +++ DW          +T   VT + + G+   C        S + TG+      ++   
Sbjct: 102 RSSSDWNRLAYYESSSKTADNVTFLNHGGEASPCLGNALSYASSNGTGSASEATVLADGT 161

Query: 166 LVSLSEQNLVDCDHECMEYEGEEACDEGCNGGLQPNAYNYIIKNGGIQTESSYPYTAETG 225
           L+S  ++ ++  +  C +   ++ C    +G   P  Y Y    GG  T   + +  E  
Sbjct: 162 LISSDQEYIIYSNVSCPKSGYDKGCGVYRSG--IPAYYGY----GG--TTKMFLFEFEMP 213

Query: 226 TQCNFNSANIG 236
           T+   NS++IG
Sbjct: 214 TETEKNSSSIG 224


>sp|P28493|PR5_ARATH PATHOGENESIS-RELATED PROTEIN 5 PRECURSOR (PR-5)
          Length = 239

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 24/93 (25%), Positives = 36/93 (37%), Gaps = 7/93 (7%)

Query: 137 VKNQGQCGSCWSFSTTGNVEGQHFISQNKLVSLSEQNLVDCDHECMEYEGEEACDEGCNG 196
           ++  G  G C      G V   +    + L  + + N+V C   C  +  ++ C  G N 
Sbjct: 137 IRPSGGSGDC---KYAGCVSDLNAACPDMLKVMDQNNVVACKSACERFNTDQYCCRGAND 193

Query: 197 GLQ---PNAYNYIIKNGGIQTESSYPYTAETGT 226
             +   P  Y+ I KN       SY Y  ET T
Sbjct: 194 KPETCPPTDYSRIFKN-ACPDAYSYAYDDETST 225


>sp|P54634|POLN_LORDV NON-STRUCTURAL POLYPROTEIN [CONTAINS: RNA-DIRECTED RNA POLYMERASE ;
           THIOL PROTEASE 3C ; HELICASE (2C LIKE PROTEIN)]
          Length = 1699

 Score = 31.3 bits (69), Expect = 3.2
 Identities = 13/31 (41%), Positives = 21/31 (66%)

Query: 17  SSRGIPPEEQSQFLEFQDKFNKKYSHEEYLE 47
           SS+G+  EE  ++   +++ N KYS EEYL+
Sbjct: 893 SSKGLSDEEYDEYKRIREERNGKYSIEEYLQ 923


>sp|Q02521|SPP2_YEAST SPLICEOSOME MATURATION PROTEIN SPP2
          Length = 185

 Score = 30.9 bits (68), Expect = 4.2
 Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 6/99 (6%)

Query: 30  LEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKF---GVNKF-ADLSS 85
           L+   K  KK   ++  ++  + K+NL   ++    +++HK  +K     ++KF  D  S
Sbjct: 6   LKLGSKTLKKNISKKTKKKNSLQKANLFDWDDAETASLSHKPQSKIKIQSIDKFDLDEES 65

Query: 86  DEFKNYYLNNKEAIFT--DDLPVADYLDDEFINSIPPEE 122
              K   +   E   T  +D P+ +Y+ ++  N +P EE
Sbjct: 66  SSKKKLVIKLSENADTKKNDAPLVEYVTEKEYNEVPVEE 104


>sp|P41901|SPR3_YEAST SPORULATION-SPECIFIC SEPTIN
          Length = 512

 Score = 30.9 bits (68), Expect = 4.2
 Identities = 17/58 (29%), Positives = 29/58 (49%), Gaps = 9/58 (15%)

Query: 60  EELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNNKEAIFTDDLPVADYLDDEFINS 117
           + +NLI +  K+D          L+ +E KN+    +E I   D+PV  +  DE +N+
Sbjct: 237 KRVNLIPVIAKSDL---------LTKEELKNFKTQVREIIRVQDIPVCFFFGDEVLNA 285


>sp|Q01532|BLH1_YEAST CYSTEINE PROTEINASE 1 (Y3) (BLEOMYCIN HYDROLASE) (BLM HYDROLASE)
          Length = 454

 Score = 30.5 bits (67), Expect = 5.5
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 11/66 (16%)

Query: 111 DDEFINS--IPPEEQTAFDWRTRGAVTPVKNQGQCGSCWSFSTTGNVEGQHFISQNKLVS 168
           DD  +N   +  ++   F+       TPV NQ   G CW F+ T         +Q +L  
Sbjct: 36  DDALLNKTRLQKQDNRVFNTVVSTDSTPVTNQKSSGRCWLFAAT---------NQLRLNV 86

Query: 169 LSEQNL 174
           LSE NL
Sbjct: 87  LSELNL 92


>sp|P24896|NU5M_CAEEL NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5
          Length = 527

 Score = 30.5 bits (67), Expect = 5.5
 Identities = 21/52 (40%), Positives = 26/52 (49%), Gaps = 7/52 (13%)

Query: 44  EYLERFEIFKSNLGKIEELNLIAINHKADTKFGVNKFADLSSDEFKNYYLNN 95
           +YL +  I+K    K  +L L  IN K  T F       LSS  FKNYYL +
Sbjct: 466 DYLAKNSIYKMKNLKFMDLFLNNINSKGYTLF-------LSSGMFKNYYLKS 510


>sp|P25648|SRB8_YEAST SUPPRESSOR OF RNA POLYMERASE B SRB8
          Length = 1427

 Score = 30.1 bits (66), Expect = 7.2
 Identities = 22/89 (24%), Positives = 44/89 (48%), Gaps = 10/89 (11%)

Query: 21   IPPEEQSQFLEFQDKFNKKYSHEEYLERFEIFKSNLGKIEELNLIAINHKADTKFGV--- 77
            +PP + S F++     +  Y  EE  ++ E F  NLG    + ++ I H+ + K+ +   
Sbjct: 1314 LPPFQVSSFVKETKLHSGDYGEEEDADQEESFSLNLG----IGIVEIAHENEQKWLIYDK 1369

Query: 78   --NKFADLSSDEFKNYYLNNKEAIFTDDL 104
              +K+    S E   ++++N    +TDD+
Sbjct: 1370 KDHKYVCTFSME-PYHFISNYNTKYTDDM 1397


>sp|Q04723|PEPC_LACLC AMINOPEPTIDASE C
          Length = 436

 Score = 30.1 bits (66), Expect = 7.2
 Identities = 11/20 (55%), Positives = 14/20 (70%)

Query: 311 NMPYWIVKNSWGADWGEQGY 330
           N   W V+NSWG D G++GY
Sbjct: 370 NSTKWKVENSWGKDAGQKGY 389


>sp|Q13867|BLMH_HUMAN BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)
          Length = 455

 Score = 29.7 bits (65), Expect = 9.4
 Identities = 10/17 (58%), Positives = 13/17 (75%)

Query: 315 WIVKNSWGADWGEQGYI 331
           W V+NSWG D G +GY+
Sbjct: 392 WRVENSWGEDHGHKGYL 408


>sp|P87362|BLMH_CHICK BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH) (AMINOPEPTIDASE H)
          Length = 455

 Score = 29.7 bits (65), Expect = 9.4
 Identities = 10/19 (52%), Positives = 14/19 (73%)

Query: 315 WIVKNSWGADWGEQGYIYL 333
           W V+NSWG D G +GY+ +
Sbjct: 392 WRVENSWGEDRGNKGYLIM 410


>sp|P70645|BLMH_RAT BLEOMYCIN HYDROLASE (BLM HYDROLASE) (BMH)
          Length = 454

 Score = 29.7 bits (65), Expect = 9.4
 Identities = 10/17 (58%), Positives = 13/17 (75%)

Query: 315 WIVKNSWGADWGEQGYI 331
           W V+NSWG D G +GY+
Sbjct: 392 WRVENSWGEDHGHKGYL 408


  Database: /home/peter/blast/data/swissprot
    Posted date:  Oct 10, 2000 10:43 AM
  Number of letters in database: 31,984,247
  Number of sequences in database:  88,780
  
Lambda     K      H
   0.317    0.136    0.414 

Lambda     K      H
   0.270   0.0477    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23348054
Number of Sequences: 88780
Number of extensions: 1039466
Number of successful extensions: 3135
Number of sequences better than 10.0: 162
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2557
Number of HSP's gapped (non-prelim): 148
length of query: 351
length of database: 31,984,247
effective HSP length: 50
effective length of query: 301
effective length of database: 27,545,247
effective search space: 8291119347
effective search space used: 8291119347
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 65 (29.7 bits)
