LOCUS       AF194338                4986 bp    DNA     linear   INV 28-MAY-2003
DEFINITION  Stylonychia lemnae macronuclear DNA polymerase catalytic subunit
            alpha gene, complete cds.
ACCESSION   AF194338
VERSION     AF194338.1  GI:7341069
KEYWORDS    .
SOURCE      Stylonychia lemnae
  ORGANISM  Stylonychia lemnae
            Eukaryota; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
            Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae;
            Stylonychia.
REFERENCE   1  (bases 1 to 4986)
  AUTHORS   Landweber,L.F., Kuo,T.C. and Curtis,E.A.
  TITLE     Evolution and assembly of an extremely scrambled gene
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 97 (7), 3298-3303 (2000)
   PUBMED   10725348
REFERENCE   2  (bases 1 to 4986)
  AUTHORS   Ardell,D.H., Lozupone,C.A. and Landweber,L.F.
  TITLE     Polymorphism, recombination and alternative unscrambling in the DNA
            polymerase alpha gene of the ciliate Stylonychia lemnae
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 4986)
  AUTHORS   Landweber,L.F., Kuo,T.-C. and Curtis,E.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-1999) Ecology and Evolutionary Biology, and
            Molecular Biology, Princeton University, Guyot Hall, Washington
            Road, Princeton, NJ 08544, USA
FEATURES             Location/Qualifiers
     source          1..4986
                     /organism="Stylonychia lemnae"
                     /macronuclear
                     /mol_type="genomic DNA"
                     /db_xref="taxon:5949"
     misc_feature    1..20
                     /note="telomere"
     mRNA            join(21..277,327..515,585..4966)
                     /product="DNA polymerase catalytic subunit alpha"
     misc_feature    21..357
                     /note="macronuclear destined sequence M1; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     5'UTR           21..145
     CDS             join(146..277,327..515,585..4838)
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="similar to Swiss-Prot Accession Number P28040"
                     /codon_start=1
                     /transl_table=6
                     /product="DNA polymerase catalytic subunit alpha"
                     /protein_id="AAO73537.1"
                     /db_xref="GI:29251556"
                     /translation="MSDNYTTQSGXEIKKIGQKSGVKNALAQLRAAREGGDKRTDQYQ
                     VEEAKRIFEEIDADEYERIXDQRKNDDFIVXDDGXGYRDHGGEIWERDDNEEVGGKKK
                     KRKLDPNEQHITBFMMPASTIRKNKGXGNSSNIQIKQKPKVTAEQSMDIMNNLLQELD
                     NKDVDELEDVNASAVMAELNKPIAFXKNEELLNKYGVTLESKQEIQVKRQLEQQQXEQ
                     TIGQHQQNANVFSKKRKLDEIQQPQIKKEHQGLNKSRQTETIIHQSSNTSYFDAKSQL
                     SHDQSMEYQSAVDDSKMSESSSAQKNAMNEGPIAFSKNQTNMSASKNDEWAQIKHQNQ
                     QAHQEFKTMEQKSAMDIQEFALPLNQDGSLSFYWIDAHGENNGADLFIFGKIYQPEIN
                     QYVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGVQLELEDIRKKRFQGI
                     TKWRCKPVTRKYAFEMLIQHGEHLFLKIKYDATFIPLPSTVQGNTFECLFGSNQSMLE
                     LFILKRKIKGPCWMTIKNPKKVTDFKKTWCRQEIEIDNPKNAEVTLDDLNKTDIPPLT
                     SLTFAFKTARSQNNTNEIAMISCLVHNNVNQEGPSQTDKFQTFTLVRKLDGKPMPFDF
                     DQKLRQKKENIQYFTNERQMIDLFVTRIFQIDPDLIVAHNLCGGIFDLLLARIQILKI
                     NHWSRIGRFKKGNIPTKKFDTGGANYGGSQWIPRQVTCGRLLVDTFLSAKELIRETNY
                     DLTHLTKVQLKKDRQDFDDDLLPQFYLASERIFQLIEHSEKDSYYTFMLMPHLSIIPL
                     TKQLTNIAGNLWFRSLQNARAERNEMLLLHEFKKKKFILPDKKPPNAKDLRRGFMGDE
                     YEENDTKGGGKKGGKRKKAKYAGGLVIEPKAGFYDNIILLLDFNSLYPSIIQEYNLCF
                     TTVNRRPTKNYDGSELKNQXKSADNAEGDEVEDVDLPDKNVNIKDAVLPXVLRDLVQK
                     RKAVKEKMKNEXDQXKLQQLEIRQKAIKLTANSMYGCLGFSSSRFHASAIAALITKTG
                     RETLLRTKDIAENKLGFNVVYGXTDSIMINTGTNQLQQSLEMGKKLKVEVNCLYKCLE
                     IEIDGXFKSLLLLKKKKYAXLRYEGVGSNEVKVIQEMKGLDMVRRXWCPLSKSIGNYV
                     LSQILSGKQXEDVVFNLNEYLSDIGEKMKSNRITLDQFIITKQLTRAISEYSDIKGQP
                     HVAVAQRLKNQGKSEADLVNNFIPYVIGAQAFDTAKSNPQLSDKAYHPDELLSSKGKI
                     TLDIDWYIXTQILXPITRLIEHIDGINIEFVAQCLGVDPKKYKYHSEKKNTDEIGDDG
                     GSIQNPILQTETEKSLKHRSIAELKVKCPSCTHNYDFPGIYQEGKDVSGLICTKCNAK
                     IPEKYVMNRVNLFLKQLLALYYQGKYECQEPSCKSMTRQLLYHNKCVNLTCKGKMVPE
                     YSEHQTNXTLRYLQGLFXIKKHLHEDSKNDSLKVETDIPFYNEYNVLQTKVDELMNRS
                     KYTKVDLGSIFGFMRQSNNKMAVSSTATAQ"
     misc_feature    402..449
                     /note="Region: conserved region A"
     misc_feature    1410..1418
                     /note="Region: conserved region E"
     misc_feature    1815..1826
                     /note="Region: conserved region D"
     misc_feature    2166..2291
                     /note="Region: conserved region IV"
     misc_feature    2679..2786
                     /note="Region: conserved region B"
     misc_feature    2892..3014
                     /note="Region: conserved region II"
     misc_feature    3141..3191
                     /note="Region: conserved region VI"
     misc_feature    3240..3365
                     /note="Region: conserved region III"
     misc_feature    3408..3431
                     /note="Region: conserved region I"
     misc_feature    3522..3563
                     /note="Region: conserved region C"
     misc_feature    3570..3584
                     /note="Region: conserved region VII"
     misc_feature    3627..3671
                     /note="Region: conserved region V"
     exon            146..277
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /number=1
     exon            327..515
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /number=2
     misc_recomb     358..359
                     /note="pointer P1-2"
     misc_feature    360..1222
                     /note="macronuclear destined sequence M2; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     exon            585..4838
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /number=3
     misc_recomb     1223..1237
                     /note="pointer P2-3"
     misc_feature    1238..1263
                     /note="macronuclear destined sequence M3; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1264..1270
                     /note="pointer P3-4"
     misc_feature    1271..1283
                     /note="macronuclear destined sequence M4; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1284..1291
                     /note="pointer P4-5"
     misc_feature    1292..1329
                     /note="macronuclear destined sequence M5; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_feature    1330..1341
                     /note="macronuclear destined sequence M6; micronuclear
                     source missing"
     misc_feature    1342..1364
                     /note="macronuclear destined sequence M7; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1365..1374
                     /note="pointer P7-8"
     misc_feature    1375..1384
                     /note="macronuclear destined sequence M8; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1385..1392
                     /note="pointer P8-9"
     misc_feature    1393..1433
                     /note="macronuclear destined sequence M9; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1434..1444
                     /note="pointer P9-10"
     misc_feature    1445..1456
                     /note="macronuclear destined sequence M10; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1457..1469
                     /note="pointer P10-11"
     misc_feature    1470..1497
                     /note="macronuclear destined sequence M11; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1498..1504
                     /note="pointer P11-12"
     misc_feature    1505..1519
                     /note="macronuclear destined sequence M12; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1520..1527
                     /note="pointer P12-13"
     misc_feature    1528..1545
                     /note="macronuclear destined sequence M13; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1546..1555
                     /note="pointer P13-14"
     misc_feature    1556..1666
                     /note="macronuclear destined sequence M14; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1667..1677
                     /note="pointer P14-15"
     misc_feature    1678..1687
                     /note="macronuclear destined sequence M15; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1688..1699
                     /note="pointer P15-16"
     misc_feature    1700..1778
                     /note="macronuclear destined sequence M16; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1779..1790
                     /note="pointer P16-17"
     misc_feature    1791..1862
                     /note="macronuclear destined sequence M17; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1863..1870
                     /note="pointer P17-18"
     misc_feature    1871..1926
                     /note="macronuclear destined sequence M18; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     1927..1934
                     /note="pointer P18-19"
     misc_feature    1935..2005
                     /note="macronuclear destined sequence M19; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2006..2012
                     /note="pointer P19-20"
     misc_feature    2013..2027
                     /note="macronuclear destined sequence M20; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2028..2036
                     /note="pointer P20-21"
     misc_feature    2037..2108
                     /note="macronuclear destined sequence M21; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2109..2118
                     /note="pointer P21-22"
     misc_feature    2119..2161
                     /note="macronuclear destined sequence M22; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2162..2173
                     /note="pointer P22-23"
     misc_feature    2174..2243
                     /note="macronuclear destined sequence M23; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     variation       2202
                     /note="as compared to micronuclear M23 sequence in GenBank
                     Accession Number AF194337; results in reading frame shift"
                     /replace=""
     misc_recomb     2244..2251
                     /note="pointer P23-24"
     misc_feature    2252..2361
                     /note="macronuclear destined sequence M24; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2362..2368
                     /note="pointer P24-25"
     misc_feature    2369..2391
                     /note="macronuclear destined sequence M25; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2392..2398
                     /note="pointer P25-26"
     misc_feature    2399..2407
                     /note="macronuclear destined sequence M26; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2408..2414
                     /note="pointer P26-27"
     misc_feature    2415..2502
                     /note="macronuclear destined sequence M27; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2503..2512
                     /note="pointer P27-28"
     misc_feature    2513..2524
                     /note="macronuclear destined sequence M28; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     2525..2537
                     /note="pointer P28-29"
     misc_feature    2538..2887
                     /note="macronuclear destined sequence M29"
     misc_recomb     2888..2899
                     /note="pointer P29-30"
     misc_feature    2900..3279
                     /note="macronuclear destined sequence M30"
     misc_recomb     3280..3292
                     /note="pointer P30-31"
     misc_feature    3293..3352
                     /note="macronuclear destined sequence M31; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     3353..3361
                     /note="pointer P31-32"
     misc_feature    3362..3378
                     /note="macronuclear destined sequence M32; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     3379..3385
                     /note="pointer P32-33"
     misc_feature    3386..3431
                     /note="macronuclear destined sequence M33; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     3432..3443
                     /note="pointer P33-34"
     misc_feature    3444..3543
                     /note="macronuclear destined sequence M34; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     3544..3555
                     /note="pointer P34-35"
     misc_feature    3556..3611
                     /note="macronuclear destined sequence M35; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     3612..3619
                     /note="pointer P35-36"
     misc_feature    3620..3690
                     /note="macronuclear destined sequence M36; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     3691..3699
                     /note="pointer P36-37"
     misc_feature    3700..3768
                     /note="macronuclear destined sequence M37; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     3769..3778
                     /note="pointer P37-38"
     misc_feature    3779..3807
                     /note="macronuclear destined sequence M38; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     3808..3814
                     /note="pointer P38-39"
     misc_feature    3815..3909
                     /note="macronuclear destined sequence M39; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     3910..3915
                     /note="pointer P39-40"
     misc_feature    3916..3930
                     /note="macronuclear destined sequence M40; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     3931..3940
                     /note="pointer P40-41"
     misc_feature    3941..3958
                     /note="macronuclear destined sequence M41; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     3959..3969
                     /note="pointer P41-42"
     misc_feature    3970..3976
                     /note="macronuclear destined sequence M42; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     3977..3988
                     /note="pointer P42-43"
     misc_feature    3989..4218
                     /note="macronuclear destined sequence M43; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     4219..4227
                     /note="pointer P43-44"
     misc_feature    4228..4235
                     /note="macronuclear destined sequence M44; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     4236..4248
                     /note="pointer P44-45"
     misc_feature    4249..4320
                     /note="macronuclear destined sequence M45; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     4321..4332
                     /note="pointer P45-46"
     misc_feature    4333..4345
                     /note="macronuclear destined sequence M46; may derive from
                     micronuclear minor locus deposited in GenBank Accession
                     Number AF194336"
     misc_recomb     4346..4357
                     /note="pointer P46-47"
     misc_feature    4358..4639
                     /note="macronuclear destined sequence M47; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     misc_recomb     4640..4644
                     /note="pointer P47-48"
     misc_feature    4645..4966
                     /note="macronuclear destined sequence M48; may derive from
                     micronuclear major locus deposited in GenBank Accession
                     Number AF194337"
     3'UTR           4839..4966
     misc_feature    4967..4986
                     /note="telomere"
ORIGIN      
        1 aaaaccccaa aaccccaaaa tcccaaatca aattaatagt tgagraataa raattgaata
       61 atrataccgc gtttaatctw agtgggaatc aaagaatgag tttataattt taaacttagt
      121 ctaaacaaar cttgcawata agaskatgag tgayaattac acaacacaaa gtggcasaga
      181 aatcaagaaa atcggctaaa aatcaggtgt taaaaacgct ctagcttaac tcagagctgc
      241 tagagagggt ggagataaga gaactgatta atattaagtm aggaactaaa tttaaagctt
      301 gcagragatg ctaatctttt acttaggtcg aagaggcaaa gagaattttt gaagagatag
      361 atgcygatga atatgaaaga atttawgatc aaaggaaaaa tgatgatttc attgtkkatg
      421 atgatggyty tggctacaga gatcatggag gtgaaatctg ggaaagagat gacaacgaag
      481 aggttggcgg taaaaagaaa aagagaaagc ttgatgtaag tataaaccaa gtcttagtct
      541 attktatcat ttaaattccg caattyactt acattactct atagccaaat gaacagcaca
      601 ttactractt tatgatgccm gcttcaacwa tcagaaagaa caaaggaavm ggcaattcta
      661 gcaatatata gataaagcaa aarcctaagg ttacwgctga gcaatctatg gacattatga
      721 acaatttgct ataagaacta gataataaag atgtygatga gttggargat gtaaaygcat
      781 cagcagttat ggctgagctt aacaaaccaa tagcctttar caaaaatgaa gaacttttga
      841 acaaatacgg agtaacttta gagtcwaagc aagaaattta agtgaaaaga caacttgaat
      901 agcarcarya tgaacagact attggctaac actaataaaa cgcgaatgta ttttcaaaga
      961 aaagaaagct agatgaaatt taacaacctt aaataaaaaa agagcattaa ggactaaata
     1021 aaagtaggta gactgaaact attattcatt aatcaagtaa cactagttat ttcgatgcta
     1081 aaagttagct atctcatgac taatctatgg aatatcaatc agctgttgat gattctaaga
     1141 tgtcagaaag tagctcagca cagaaaaatg caatgaatga aggtcctata gcattcagta
     1201 aaaattaaac taatatgtct gcatctaaga atgatgaatg ggcttaaatc aaacatcaga
     1261 actaataagc tcattaagag ttcaaaacta tggagtaaaa atcagctatg gatatttaag
     1321 aatttgctct cccgttaaat caagatggct cattatcatt ctactggatt gatgcacatg
     1381 gggaaaataa tggcgctgat ttattcatat tcggaaaaat ctatcaacca gagatcaatt
     1441 aatacgtatc ctgctcaatg aaagtaaatg gaatgtaaag agagatatat gcgcttccta
     1501 aaatgcaaaa gggtaaagct agaggaactt tgacaagaga agaggaaaat caactagtta
     1561 gaggtgtaca actagaacta gaagatatta gaaagaaaag attccagggt attactaaat
     1621 ggagatgcaa gccagttacc aggaaatatg cattcgaaat gcttattcaa catggagagc
     1681 atttgttctt gaaaatcaag tatgatgcaa catttatccc tctaccaagt actgtttaag
     1741 gaaatacatt tgaatgctta tttggctcta actaaagcat gcttgaactc ttcattctta
     1801 aaaggaaaat taaaggtccc tgctggatga cgataaaaaa tccaaagaaa gttactgact
     1861 tcaagaaaac atggtgtaga taagagattg aaattgataa tcctaaaaat gcagaggtta
     1921 cattggatga tcttaacaaa actgatatcc caccactaac ctccttaaca ttcgcattca
     1981 agactgccag atctcagaat aacacaaatg agattgctat gatttcttgc ttggttcata
     2041 acaatgttaa tcaggaagga ccatcttaga ctgacaaatt ttagacattt actttagtca
     2101 ggaagctcga tggcaaacca atgccatttg attttgacta aaagcttaga tagaagaaag
     2161 agaatattta atacttcact aatgaaagat aaatgataga cttatttgta actagaattt
     2221 tctaaattga tccagatctt attgtggctc acaatctatg tgggggaata ttcgatctct
     2281 tactagctag aatttaaata cttaaaatta accactggag cagaattggt agatttaaga
     2341 aaggaaacat tcctactaag aagtttgata ctggtggtgc taattacgga ggatcctaat
     2401 ggattccaag ataagttact tgtggtagat tgttagttga tactttcctc tctgccaagg
     2461 agctgatcag agaaaccaac tatgacctta ctcatttgac aaaagtctag ctcaagaaag
     2521 acagataaga ttttgatgat gatttgctac ctcagttcta tttagcatct gaacgcatat
     2581 tttagctcat cgagcattct gagaaagatt cctactatac ttttatgctt atgcctcatc
     2641 tatcaattat ccccttaacc aaacaactaa ctaacattgc aggtaactta tggtttaggt
     2701 ctctctaaaa cgccagagct gaaagaaacg agatgctttt gttgcatgaa ttcaagaaga
     2761 agaaattcat tttaccagat aaaaagccac ctaatgctaa agaccttaga agaggattta
     2821 tgggagatga atatgaagag aacgatacca aaggaggagg taaaaaggga ggtaagagaa
     2881 agaaggcgaa gtatgctgga ggtctcgtta tagagccaaa agcaggtttc tatgacaaca
     2941 ttatcttgct tttggatttc aacagtttgt atccctcaat tattcaagag tacaacctct
     3001 gctttactac agtaaacaga agaccaacca agaactacga tggcagtgaa ttgaaaaatc
     3061 aatdcaaatc tgctgataac gctgarggag aygaagtcga agatgttgat cttccagata
     3121 agaatgtgaa catcaaggat gctgtacttc caartgtact cagagatttg gtttaaaaga
     3181 gaaaagctgt maaggaaaag atgaagaatg aaraggatca ggygaarctc taacaacttg
     3241 aaatcagata gaaagctatt aagytgactg ctaacagtat gtatggttgc ttrggtttta
     3301 gttcctccag attccacgct tcagctattg cagctctgat tacaaagact ggtagagaaa
     3361 cccttctaag aacaaaagat attgctgaga ataagytagg ctttaacgtt gtgtatggtg
     3421 awactgattc tattatgatc aatactggta ctaaycaact tcagtaatca cttgagatgg
     3481 gcaaaaaact taaagttgaa gttaattgyc tctataaatg ccttgaaatw gaaatwgatg
     3541 gtgktttcaa gagtttactt ttactaaaga aaaagaaata tgctrctttg agrtatgaag
     3601 gtgttggytc yaatgaagtc aaagtaattc aagaaatgaa aggtcttgat atggtyagaa
     3661 gagaktggtg tcctctctcr aagtctattg gaaattatgt tctcagccaa attttatcag
     3721 gcaaryaarg rgargatgta gtattcaacc tgaaygaata cttatctgat attggagaga
     3781 aaatgaagag caatagaatc actctagatc aattcatcat aacaaagcaa cttacwagag
     3841 cyatttcaga gtattctgat atcaaaggat aaccmcatgt ggcagttgct caaagactta
     3901 aaaattaagg aaagagtgag gcagatcttg tcaataattt catcccttat gttattggag
     3961 ctcaagcatt tgatacagct aagtcaaacc cacaattatc agataaggct tatcatccag
     4021 atgagctctt atcctccaag ggtaagatta cycttgatat tgattggtat attrctactc
     4081 agattcttcy tccaattact agacttattg arcacatcga tggkattaat atcgagttcg
     4141 ttgctcaatg ccttggtgtt gacccaaaga agtataaata tcactctgag aaaaagaata
     4201 cagatgaaat aggtgatgat ggtggatcaa tctagaatcc tattctttaa actgaaactg
     4261 aaaaaagtct taaacacaga tcaattgccg agcttaaagt kaaatgccca tcttgcactc
     4321 ataattatga cttcccaggt atttaccaag aaggaaaaga tgtgtctggc ttratttgya
     4381 ctaaatgcaa tgctaagata ccagaaaaat atgtgatgaa cagagtkaat ctatttttga
     4441 agcagctatt agcyctatat tactagggta aatatgagtg ctargagcct tcttgcaaga
     4501 gtatgactcg ttaactcctc tatcataaca aatgtgttaa tctaacttgt aagggyaara
     4561 tggtaccaga atactcagag catcaaacya acgmcacact cagatatctt caaggcctat
     4621 ttamcattaa aaaacacctt catgaagaca gcaaaaatga ttcattraag gttgaaaccg
     4681 acatcccatt ctataatgaa tataatgttt tacagacaaa agtwgatgaa ctaatgaata
     4741 gaagtaaata taccaaggtt gacytaggaa gtatattygg cttcatgagg tagagcaata
     4801 ataaaatggc tgtaagtagt acggcaactg cttaatgaaa agattttcag tcaaattaag
     4861 tacttatatt tatgtgttgm gaaaaaggag tattttttgg aaagatatat gatttattaa
     4921 taataaaaga gtawtttaat ctttgcttgc agggttttag cattttgggg ttttggggtt
     4981 ttgggg
//

